Pyk2 contributes to reepithelialization by promoting MMP expression. Focus on "Delayed skin wound repair in proline-rich protein tyrosine kinase 2 knockout mice"

American Journal of Physiology - Cell Physiology

Volumn 306, Issue 10, 2014, Pages

  Graves, Dana T ^a   Wu, Yingying ^a,b   Badadani, Mallikarjun ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b SICHUAN UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

FOCAL ADHESION KINASE 2; MATRIX METALLOPROTEINASE; TISSUE INHIBITOR OF METALLOPROTEINASE;

CELL MIGRATION; CELL PROLIFERATION; CELL TYPE; EDITORIAL; EPITHELIZATION; KERATINOCYTE; KNOCKOUT MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SKIN INJURY; WOUND CLOSURE; WOUND HEALING IMPAIRMENT;

ANIMALS; FOCAL ADHESION KINASE 2; HUMANS; KERATINOCYTES; MALE; PROTEIN KINASE C-DELTA; RE-EPITHELIALIZATION; SKIN;

EID: 84900562609     PISSN: 03636143     EISSN: 15221563     Source Type: Journal    
DOI: 10.1152/ajpcell.00098.2014     Document Type: Editorial

References (9)

1. Campbell L, Williams H, Crompton RA, Cruickshank SM, Hardman MJ. Nod2 deficiency impairs inflammatory and epithelial aspects of the cutaneous wound-healing response. J Pathol 229: 121-131, 2013.
2. Jiang XP, Zhang DX, Teng M, Zhang Q, Zhang JP, Huang YS. Downregulation of CD9 in keratinocyte contributes to cell migration via upregulation of matrix metalloproteinase-9. PLos One 8: e77806, 2013.
3. Koppel AC, Kiss A, Hindes A, Burns CJ, Marmer BL, Goldberg G, Blumenberg M, Efimova T. Delayed skin wound repair in proline-rich protein tyrosine kinase 2 knockout mice. Am J Physiol Cell Physiol (March 5, 2014). doi:10.1152/ajpcell.00331.2013.
4. Kyriakides TR, Wulsin D, Skokos EA, Fleckman P, Pirrone A, Shipley JM, Senior RM, Bornstein P. Mice that lack matrix metalloproteinase-9 display delayed wound healing associated with delayed reepithelialization and disordered collagen fibrillogenesis. Matrix Biol 28: 65-73, 2009.
5. Martins VL, Caley M, O'Toole EA. Matrix metalloproteinases and epidermal wound repair. Cell Tissue Res 351: 255-268, 2013.
6. Peplow PV, Chatterjee MP. A review of the influence of growth factors and cytokines in in vitro human keratinocyte migration. Cytokine 62: 1-21, 2013.
7. Ponugoti B, Xu F, Zhang C, Tian C, Pacios S, Graves DT. FOXO1 promotes wound healing through the up-regulation of TGF-β1 and prevention of oxidative stress. J Cell Biol 203: 327-343, 2013.
8. Salonurmi T, Parikka M, Kontusaari S, Pirila E, Munaut C, Salo T, Tryggvason K. Overexpression of TIMP-1 under the MMP-9 promoter interferes with wound healing in transgenic mice. Cell Tissue Res 315: 27-37, 2004.
9. White DP, Caswell PT, Norman JC. αvβ3-and α5β1-integrin recycling pathways dictate downstream Rho kinase signaling to regulate persistent cell migration. J Cell Biol 177: 515-525, 2007.