Exposure to rosiglitazone, a PPAR-γ agonist, in late gestation reduces the abundance of factors regulating cardiac metabolism and cardiomyocyte size in the sheep fetus

American Journal of Physiology - Regulatory Integrative and Comparative Physiology

Volumn 306, Issue 6, 2014, Pages

  Lie, Shervi ^a   Hui, Melisa ^a   McMillen, I Caroline ^a   Muhlhausler, Beverly S ^a   Posterino, Giuseppe S ^b   Dunn, Stacey L ^a   Wang, Kimberley C ^a   Botting, Kimberley J ^a   Morrison, Janna L ^a  

^a UNIVERSITY OF SOUTH AUSTRALIA   (Australia)

^b LA TROBE UNIVERSITY   (Australia)

Author keywords

Adiponectin; Binucleated; Contractility; Fatty acid; Fetus; Glucose transporter; Insulin; Mononucleated; Pregnancy; Programming

Indexed keywords

ADIPONECTIN RECEPTOR 1; CALCIUM ION; CARNITINE PALMITOYLTRANSFERASE I; GLUCOSE; INSULIN; INSULIN RECEPTOR; INSULIN RECEPTOR SUBSTRATE 1; MESSENGER RNA; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHOINOSITIDE DEPENDENT PROTEIN KINASE 1; PROTEIN KINASE B; PROTEIN P110; PROTEIN P85; ROSIGLITAZONE; 2,4 THIAZOLIDINEDIONE DERIVATIVE; ADIPONECTIN; ANTIDIABETIC AGENT; FATTY ACID; GLUCOSE TRANSPORTER; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PROTEIN KINASE;

ADULT; ANIMAL CELL; ARTICLE; BIRTH; CELL MATURATION; CELL SIZE; CONTROLLED STUDY; DRUG EXPOSURE; ENZYME ACTIVE SITE; EXPERIMENTAL SHEEP; FATTY ACID OXIDATION; FEMALE; FETUS; GENE EXPRESSION; GLUCOSE TRANSPORT; HEART DEVELOPMENT; HEART FUNCTION; HEART MUSCLE; HEART MUSCLE CELL; HEART MUSCLE CONTRACTILITY; HEART MUSCLE METABOLISM; HEART VENTRICLE HYPERTROPHY; MALE; NONHUMAN; PREGNANCY; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING; ANIMAL; BINUCLEATED; CYTOLOGY; DOMESTIC SHEEP; DRUG EFFECT; DRUG POTENTIATION; GENE EXPRESSION REGULATION; GENETICS; GESTATIONAL AGE; HEART; HEART CONTRACTION; METABOLISM; MONONUCLEATED; MUSCLE CONTRACTILITY; PHYSIOLOGY; PRENATAL DEVELOPMENT; PROGRAMMING;

ADIPONECTIN; BINUCLEATED; CONTRACTILITY; FATTY ACID; FETUS; GLUCOSE TRANSPORTER; INSULIN; MONONUCLEATED; PREGNANCY; PROGRAMMING;

ANIMALS; CELL SIZE; FATTY ACIDS; FEMALE; FETUS; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GESTATIONAL AGE; HEART; HYPOGLYCEMIC AGENTS; INSULIN; MYOCARDIAL CONTRACTION; MYOCARDIUM; MYOCYTES, CARDIAC; PPAR GAMMA; PREGNANCY; PROTEIN KINASES; RECEPTOR, INSULIN; SHEEP, DOMESTIC; THIAZOLIDINEDIONES;

EID: 84900546369     PISSN: 03636119     EISSN: 15221490     Source Type: Journal    
DOI: 10.1152/ajpregu.00431.2013     Document Type: Article

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