Role for high-glucose-induced protein O-GlcNAcylation in stimulating cardiac fibroblast collagen synthesis

American Journal of Physiology - Cell Physiology

Volumn 306, Issue 9, 2014, Pages

  Aguilar, Hugo ^b   Fricovsky, Eduardo ^b,c   Ihm, Sang ^e   Schimke, Magdalena ^d   Maya Ramos, Lisandro ^b   Aroonsakool, Nakon ^b   Ceballos, Guillermo ^a   Dillmann, Wolfgang ^b   Villarreal, Francisco ^b   Ramirez Sanchez, Israel ^a  

^a INSTITUTO POLITÉCNICO NACIONAL   (Mexico)

^b UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^c UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^d UNIVERSITY OF INNSBRUCK   (Austria)

^e The Catholic University of Korea   (South Korea)

Author keywords

Cardiomyopathy; Diabetes; Fibroblast; Fibrosis; Glycosylation

Indexed keywords

ACETYLGLUCOSAMINIDASE; ARGINASE; ARGINASE 1; ARGINASE II; COLLAGEN TYPE 1; COLLAGEN TYPE 3; GLUCOSE; SMAD2 PROTEIN; SMAD3 PROTEIN; SMAD7 PROTEIN; TRANSCRIPTION FACTOR SP1; TRANSFORMING GROWTH FACTOR BETA1; UNCLASSIFIED DRUG;

ACYLATION; ADENOVIRUS; ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL CULTURE; CELL LYSATE; CHROMATIN IMMUNOPRECIPITATION; COLLAGEN SYNTHESIS; CONTROLLED STUDY; ENZYME ACTIVITY; FIBROBLAST; GENE OVEREXPRESSION; GLUCOSE INTAKE; HEART MUSCLE CELL; HEART MUSCLE FIBROSIS; MALE; NONHUMAN; O GLCNACYLATION; PRIORITY JOURNAL; RAT; SIGNAL TRANSDUCTION; UREA CYCLE; WESTERN BLOTTING;

CARDIOMYOPATHY; DIABETES; FIBROBLAST; FIBROSIS; GLYCOSYLATION;

ACETYLGLUCOSAMINIDASE; ANIMALS; ARGINASE; CELLS, CULTURED; COLLAGEN; DIABETIC CARDIOMYOPATHIES; FIBROBLASTS; GLUCOSE; GLYCOSYLATION; MALE; MYOCARDIUM; PROTEIN PROCESSING, POST-TRANSLATIONAL; RATS; RATS, SPRAGUE-DAWLEY; SIGNAL TRANSDUCTION; SMAD PROTEINS; SP1 TRANSCRIPTION FACTOR; TIME FACTORS; TRANSFECTION; TRANSFORMING GROWTH FACTOR BETA1; UP-REGULATION;

EID: 84900540044     PISSN: 03636143     EISSN: 15221563     Source Type: Journal    
DOI: 10.1152/ajpcell.00251.2013     Document Type: Article

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