Noncompetitive inhibition of indolethylamine-N-methyltransferase by N, N-dimethyltryptamine and N, N-dimethylaminopropyltryptamine

Biochemistry

Volumn 53, Issue 18, 2014, Pages 2956-2965

  Chu, Uyen B ^a   Vorperian, Sevahn K ^a,b   Satyshur, Kenneth ^c   Eickstaedt, Kelsey ^a   Cozzi, Nicholas V ^a   Mavlyutov, Timur ^a   Hajipour, Abdol R ^d   Ruoho, Arnold E ^a  

^a UNIVERSITY OF WISCONSIN SCHOOL OF MEDICINE AND PUBLIC HEALTH   (United States)

^b Madison West High School   (United States)

^c UNIVERSITY OF WISCONSIN   (United States)

^d ISFAHAN UNIVERSITY OF TECHNOLOGY   (Iran)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS;

ALLOSTERIC CONTROL; BIOCHEMICAL PATHWAY; COMPUTER MODELING; KINETIC MECHANISM; METHYLTRANSFERASES; NONCOMPETITIVE INHIBITIONS; S ADENOSYL L METHIONINES; TRYPTAMINE DERIVATIVES;

ENZYMES;

INDOLE DERIVATIVE; INDOLETHYLAMINE N METHYLTRANSFERASE; METHYLTRANSFERASE; N,N DIMETHYLAMINOPROPYLTRYPTAMINE; N,N DIMETHYLTRYPTAMINE; NICOTINAMIDE METHYLTRANSFERASE; PHENYLETHANOLAMINE N METHYLTRANSFERASE; UNCLASSIFIED DRUG;

ALLOSTERISM; ANIMAL TISSUE; ARTICLE; BINDING SITE; COMPETITIVE INHIBITION; CONTROLLED STUDY; CRYSTAL STRUCTURE; ENZYME ACTIVITY; ENZYME INHIBITION; HUMAN; HYDROGEN BOND; IC 50; KINETICS; LUNG HOMOGENATE; MOLECULAR INTERACTION; NONHUMAN; PRIORITY JOURNAL; RABBIT;

ANIMALS; ENZYME INHIBITORS; KINETICS; LUNG; METHYLTRANSFERASES; MODELS, MOLECULAR; MOLECULAR DOCKING SIMULATION; N,N-DIMETHYLTRYPTAMINE; RABBITS; TRYPTAMINES;

EID: 84900533818     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi500175p     Document Type: Article

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