ATP acting through P2Y receptors causes activation of podocyte TRPC6 channels: Role of podocin and reactive oxygen species

American Journal of Physiology - Renal Physiology

Volumn 306, Issue 9, 2014, Pages

  Roshanravan, Hila ^a   Dryer, Stuart E ^a,b  

^a University of Houston   (United States)

^b BAYLOR COLLEGE OF MEDICINE   (United States)

Author keywords

Glomerular filtration; Nadph oxidase; Podocin; Podocyte; Purinergic; Trpc6

Indexed keywords

1 [2 (4 METHOXYPHENYL) 2 [3 (4 METHOXYPHENYL)PROPOXY]ETHYL] 1H IMIDAZOLE; ADENOSINE DIPHOSPHATE; ADENOSINE TRIPHOSPHATE; GUANINE NUCLEOTIDE BINDING PROTEIN; NUCLEOTIDE; PHOSPHOLIPASE A2 INHIBITOR; PODOCIN; PURINERGIC P2Y RECEPTOR; REACTIVE OXYGEN METABOLITE; SCAFFOLD PROTEIN; SURAMIN; TEMPOL; TRANSIENT RECEPTOR POTENTIAL CHANNEL 6; URIDINE DIPHOSPHATE; URIDINE TRIPHOSPHATE;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELL ACTIVATION; CELL FUNCTION; CELL LINE; CONTROLLED STUDY; DIAPHRAGM; ENZYME INHIBITION; ENZYME MECHANISM; EX VIVO STUDY; EXPLANT; FOOT; GENE EXPRESSION; GLOMERULOPATHY; GLOMERULUS BASEMENT MEMBRANE; GLOMERULUS CAPILLARY; GLOMERULUS FILTRATION; KIDNEY FUNCTION; KIDNEY TRANSPLANTATION; MEMBRANE BIOLOGY; MOUSE; NONHUMAN; PODOCYTE; PRIORITY JOURNAL; RAT; SIGNAL TRANSDUCTION; WHOLE CELL PATCH CLAMP;

GLOMERULAR FILTRATION; NADPH OXIDASE; PODOCIN; PODOCYTE; PURINERGIC; TRPC6;

ADENOSINE TRIPHOSPHATE; ANIMALS; ANTIOXIDANTS; CALCIUM SIGNALING; CELL LINE; DOSE-RESPONSE RELATIONSHIP, DRUG; GENE KNOCKDOWN TECHNIQUES; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; ION CHANNEL GATING; MALE; MEMBRANE POTENTIALS; MEMBRANE PROTEINS; MICE; PHOSPHOLIPASE A2 INHIBITORS; PHOSPHOLIPASES A2; PODOCYTES; PURINERGIC P2Y RECEPTOR ANTAGONISTS; RATS; RATS, SPRAGUE-DAWLEY; REACTIVE OXYGEN SPECIES; RECEPTORS, PURINERGIC P2Y; RNA INTERFERENCE; TRANSFECTION; TRPC CATION CHANNELS; TYPE C PHOSPHOLIPASES;

EID: 84900531283     PISSN: 1931857X     EISSN: 15221466     Source Type: Journal    
DOI: 10.1152/ajprenal.00661.2013     Document Type: Article

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