Screening for impaired glucose tolerance in obese children and adolescents: A validation and implementation study

Pediatric Obesity

Volumn 9, Issue 1, 2014, Pages 17-25

  Morandi, A ^a   Maschio, M ^a   Marigliano, M ^a   Miraglia Del Giudice, E ^b   Moro, B ^c   Peverelli, P ^d   Maffeis, C ^a  

^a UNIVERSITY OF VERONA   (Italy)

^b SECOND UNIVERSITY OF NAPLES   (Italy)

^c UNIVERSITY HOSPITAL OF PADOVA   (Italy)

^d SAN MARTINO HOSPITAL   (Italy)

Author keywords

Fasting plasma glucose; impaired glucose tolerance; oral glucose tolerance test; triglycerides

Indexed keywords

GLUCOSE; HEMOGLOBIN A1C; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; LOW DENSITY LIPOPROTEIN CHOLESTEROL; TRIACYLGLYCEROL;

ADOLESCENT; ARTICLE; BLOOD ANALYSIS; BODY HEIGHT; BODY MASS; BODY WEIGHT; CANADA; CHILD; CHILDHOOD OBESITY; CHOLESTEROL BLOOD LEVEL; CLINICAL EXAMINATION; DIAGNOSTIC TEST ACCURACY STUDY; DIASTOLIC BLOOD PRESSURE; FAMILY HISTORY; FEMALE; GLUCOSE BLOOD LEVEL; GLUCOSE METABOLISM; GLUCOSE TOLERANCE; GROWTH CURVE; HUMAN; IMPAIRED GLUCOSE TOLERANCE; INSULIN RELEASE; ITALY; MAJOR CLINICAL STUDY; MALE; MEASUREMENT ACCURACY; ORAL GLUCOSE TOLERANCE TEST; PHYSICAL EXAMINATION; PREDICTIVE VALUE; PREVALENCE; PRIORITY JOURNAL; SCREENING; SENSITIVITY AND SPECIFICITY; SYSTOLIC BLOOD PRESSURE; TRIACYLGLYCEROL BLOOD LEVEL; VALIDATION STUDY; WAIST CIRCUMFERENCE; WAIST TO HEIGHT RATIO;

FASTING PLASMA GLUCOSE; IMPAIRED GLUCOSE TOLERANCE; ORAL GLUCOSE TOLERANCE TEST; TRIGLYCERIDES;

ADOLESCENT; BLOOD GLUCOSE; BODY MASS INDEX; CHILD; DIABETES MELLITUS, TYPE 2; FASTING; FEMALE; GLUCOSE INTOLERANCE; GLUCOSE TOLERANCE TEST; HUMANS; ITALY; MALE; MASS SCREENING; OBESITY; PREVALENCE; RISK ASSESSMENT; TRIGLYCERIDES;

EID: 84900525533     PISSN: 20476302     EISSN: 20476310     Source Type: Journal    
DOI: 10.1111/j.2047-6310.2012.00136.x     Document Type: Article

References (34)

1. Nakamura Y, Saitoh S, Takagi S, et al. Impact of abnormal glucose tolerance, hypertension and other risk factors on coronary artery disease. Circ J 2007; 71: 20-25.
2. Rasmussen SS, Glumer C, Sandbaek A, Lauritzen T, Borch-Johnsen K,. Determinants of progression from impaired fasting glucose and impaired glucose tolerance to diabetes in a high-risk screened population: 3 year follow-up in the ADDITION study, Denmark. Diabetologia 2008; 51: 249-257.
3. Weiss R, Takasali SE, Tamborlane WV, Burgert TS, Savoye M, Caprio S,. Predictors of changes in glucose tolerance status in obese youth. Diabetes Care 2005; 28: 902-909.
4. Goran MI, Shaibi GQ, Weigensberg MJ, Davis JN, Cruz ML,. Deterioration of insulin sensitivity and beta-cell function in overweight Hispanic children during pubertal transition: a longitudinal assessment. Int J Pediatr Obes 2006; 1: 139-145.
5. Invitti C, Guzzaloni G, Gilardini L, Morabito F, Viberti G,. Prevalence and concomitants of glucose intolerance in European obese children and adolescents. Diabetes Care 2003; 26: 118-124.
6. Cambuli VM, Incani M, Pilia S, et al. Oral glucose tolerance test in Italian overweight/obese children and adolescents results in a very high prevalence of impaired fasting glycaemia, but not of diabetes. Diabetes Metab Res Rev 2009; 25: 528-534.
7. Wabitsch M, Hauner H, Hertrampf M, et al. Type II diabetes mellitus and impaired glucose regulation in Caucasian children and adolescents with obesity living in Germany. Int J Obes Relat Metab Disord 2004; 28: 307-313.
8. Baranowski T, Cooper DM, Harrell J, et al. Presence of diabetes risk factors in a large U.S. eighth-grade Cohort. Diabetes Care 2006; 29: 212-217.
9. Li C, Zhao G, Ford ES Mokdad AH,. Prevalence of pre-diabetes and its association with clustering of cardiometabolic risk factors and hyperinsulinemia among U.S. adolescents. Diabetes Care 2009; 32: 342-347.
10. Maffeis C, Pinelli L, Brambilla P, et al. Fasting Plasma Glucose (FPG) and the risk of impaired glucose tolerance in obese children and adolescents. Obesity 2010; 18: 1437-1442.
11. Reinehr T, Wabitsch M, Kleber M, de, Sousa G, Denzer C, Toschke AM,. Parental diabetes, pubertal stage, and extreme obesity are the main risk factors for prediabetes in children and adolescents: a simple risk score to identify children at risk for prediabetes. Pediatr Diabetes 2009; 10: 395-400.
12. Morrison KM, Xu L, Tarnopolsky M, Yusuf Z, Atkinson SA, Yusuf S,. Screening for dysglycemia in overweight youth presenting for weight management. Diabetes Care 2012; 35: 711-716.
13. Goran MI, Bergman RN, Avila Q,. Impaired glucose tolerance and reduced beta-cell function in overweight Latino children with a positive family history for type 2 diabetes. J Clin Endocrinol Metab 2004; 89: 207-212.
14. Sinha R, Fisch G, Teague B, et al. Prevalence of impaired glucose tolerance among children and adolescents with marked obesity. N Engl J Med 2002; 346: 802-810.
15. American Diabetes Association. Diagnosis and classification of diabetes mellitus. Diabetes Care 2012; 35 (Suppl. 1): S64-S71.
16. American Diabetes Association. Type 2 diabetes in children and adolescents. Pediatrics 2000; 105: 671-680.
17. Cole TJ, Bellizzi MC, Flegal KM, Dietz WH,. Establishing a standard definition for child overweight and obesity worldwide: international survey. BMJ 2000; 320: 1240-1243.
18. Maffeis C, Banzato C, Talamini G, Obesity Study Group of the Italian Society of Pediatric Endocrinology and Diabetology. Waist-to-height ratio, a useful index to identify high metabolic risk in overweight children. J Pediatr 2008; 152: 207-213.
19. Zoppi G, Bressan F, Luciano A,. Height and weight reference charts for children aged 2-18 years from Verona, Italy. Eur J Clin Nutr 1996; 50: 462-468.
20. Sacks DB, Bruns DE, Goldstein DE, Maclaren NK, McDonald JM, Parrott M,. Guidelines and recommendations for laboratory analysis in the diagnosis and management of diabetes mellitus. Clin Chem 2002; 48: 436-472.
21. DeLong ER, DeLong DM, Clarke-Pearson DL,. Comparing the areas under two or more correlated receiver operating characteristic curves: a nonparametric approach. Biometrics 1988; 44: 837-845.
22. Pencina MJ, D'Agostino RB Sr, D'Agostino RB Jr, Vasan RS,. Evaluating the added predictive ability of a new marker: from area under the ROC curve to reclassification and beyond. Stat Med 2008; 27: 157-172.
23. Barlow SE, the Expert Committee. Expert Committee recommendations regarding the prevention, assessment, and treatment of child and adolescent overweight and obesity: report. Pediatrics 2007; 120: S164-S192.
24. Meigs JB, Williams K, Sullivan LM, et al. Using metabolic syndrome traits for efficient detection of impaired glucose tolerance. Diabetes Care 2004; 27: 1417-1426.
25. Simental-Mendía LE, Rodríguez-Morán M, Guerrero-Romero F,. The product of fasting glucose and triglycerides as surrogate for identifying insulin resistance in apparently healthy subjects. Metab Syndr Relat Disord 2008; 6: 299-304.
26. Grandone A, Amato A, Luongo C, Santoro N, Perrone L, Miraglia del Giudice E,. High-normal fasting glucose levels are associated with increased prevalence of impaired glucose tolerance in obese children. J Endocrinol Invest 2008; 31: 1098-1102.
27. Nowicka P, Santoro N, Liu H, et al. Utility of hemoglobin A(1c) for diagnosing prediabetes and diabetes in obese children and adolescents. Diabetes Care 2011; 34: 1306-1311.
28. Calì AMG, Bonadonna RC, Trombetta M, Weiss R, Caprio S,. Metabolic abnormalities underlying the different prediabetes phenotypes in obese adolescents. J Clin Endocrinol Metab 2008; 93: 1767-1773.
29. Weiss R, Gillis D,. Patho-physiology and dynamics of altered glucose metabolism in obese children and adolescents. Int J Pediatr Obes 2008; 3 (Suppl. 1): 15-20.
30. Bacha F, Lee S, Gungor N, Arslanian SA,. From pre-diabetes to type 2 diabetes in obese youth. Diabetes Care 2010; 33: 2225-2231.
31. O' Hanesian MA, Rosner B, Bishop LM, Sacks FM,. Effects of inherent responsiveness to diet and day-to-day diet variation on plasma lipoprotein concentrations. Am J Clin Nutr 1996; 64: 53-59.
32. Gilardini L, Girola A, Morabito F, Invitti C,. Fasting glucose is not useful in identifying obese white children with impaired glucose tolerance. J Pediatr 2006; 149: 282.
33. Brufani C, Ciampalini P, Grossi A, et al. Glucose tolerance status in 510 children and adolescents attending an obesity clinic in Central Italy. Pediatr Diabetes 2010; 11: 47-54.
34. Weiss R, Dzjura JD, Burgert TS, Taksali SE, Tamborlane WV, Caprio S,. Ethnic differences in beta cell adaptation to insulin resistance in obese children and adolescents. Diabetologia 2006; 49: 571-579.