Adipose-specific knockout of Seipin/Bscl2 results in progressive lipodystrophy

Diabetes

Volumn 63, Issue 7, 2014, Pages 2320-2331

  Liu, Lu ^a   Jiang, Qingqing ^a   Wang, Xuhong ^b   Zhang, Yuxi ^c   Lin, Ruby C Y ^c   Lam, Sin Man ^d   Shui, Guanghou ^d   Zhou, Linkang ^e   Li, Peng ^e   Wang, Yuhui ^a   Cui, Xin ^a   Gao, Mingming ^a   Zhang, Ling ^a   Lv, Ying ^a   Xu, Guoheng ^a   Liu, George ^a   Zhao, Dong ^b   Yang, Hongyuan ^c  

^a PEKING UNIVERSITY HEALTH SCIENCE CENTER   (China)

^b CAPITAL MEDICAL UNIVERSITY   (China)

^c UNIVERSITY OF NEW SOUTH WALES   (Australia)

^d INSTITUTE OF GENETICS AND DEVELOPMENTAL BIOLOGY   (China)

^e Tsinghua University   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ADIPONECTIN; CERAMIDE; CHOLESTEROL; FAS ANTIGEN; FAT DROPLET; FATTY ACID; GLUCOSE; GLUCOSE TRANSPORTER 4; GLYCEROL; INSULIN; INSULIN RECEPTOR SUBSTRATE 1; LEPTIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PROTEIN KINASE B; RESISTIN; ROSI; ROSIGLITAZONE; TRIACYLGLYCEROL; UNCLASSIFIED DRUG;

ADIPOCYTE; ADIPOSE TISSUE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BERARDINELLI SEIP CONGENITAL LIPODYSTROPHY TYPE 2 GENE; BROWN ADIPOSE TISSUE; CELL DIFFERENTIATION; CELL INFILTRATION; CELL SURVIVAL; CHOLESTEROL BLOOD LEVEL; CONGENITAL GENERALIZED LIPODYSTROPHY; CONTROLLED STUDY; DOWN REGULATION; ENDOPLASMIC RETICULUM STRESS; ENZYME PHOSPHORYLATION; FAS GENE; FAT MASS; FATTY ACID BLOOD LEVEL; FATTY ACID OXIDATION; FATTY LIVER; GENE; GENE EXPRESSION; GENE INACTIVATION; GLUCOSE BLOOD LEVEL; GLUCOSE HOMEOSTASIS; GLUCOSE TOLERANCE; GLUCOSE TOLERANCE TEST; GLUCOSE TRANSPORTER 4 GENE; HYPERTROPHY; INSULIN RECEPTOR SUBSTRATE 1 GENE; INSULIN RESISTANCE; INSULIN SENSITIVITY; INSULIN TOLERANCE TEST; LIPID HOMEOSTASIS; LIPID METABOLISM; LIPID STORAGE; LIPIDOMICS; LIPOLYSIS; LIVER HISTOLOGY; LIVER WEIGHT; LONG TERM SURVIVAL; MACROPHAGE; METABOLIC PARAMETERS; MICROARRAY ANALYSIS; MOUSE; NONHUMAN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA GENE; PRIORITY JOURNAL; PROADIPOCYTE; PROMOTER REGION; PROTEIN KINASE B GENE; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; SCD1 GENE; TRIACYLGLYCEROL BLOOD LEVEL; UPREGULATION; WEIGHT GAIN; WHITE ADIPOSE TISSUE; WILD TYPE;

ADIPOSE TISSUE; ADIPOSE TISSUE, BROWN; ANIMALS; DIET, HIGH-FAT; DISEASE PROGRESSION; GENE KNOCKOUT TECHNIQUES; HETEROTRIMERIC GTP-BINDING PROTEINS; INSULIN RESISTANCE; LIPID METABOLISM; LIPODYSTROPHY; MALE; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; OBESITY; PPAR GAMMA;

EID: 84900468420     PISSN: 00121797     EISSN: 1939327X     Source Type: Journal    
DOI: 10.2337/db13-0729     Document Type: Article

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