Platelet microparticle generation assay for detection of HIT antibodies: Advance, retreat, or too soon to tell?

Thrombosis Research

Volumn 133, Issue 6, 2014, Pages 957-958

  Warkentin, Theodore E ^a  

^a MCMASTER UNIVERSITY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE DIPHOSPHATE; APYRASE; CARBON 14; CITRIC ACID; DIVALENT CATION; FLUORESCEIN; GLYCOPROTEIN IIB; HEPARIN; HEPARIN PLATELET FACTOR 4 ANTIBODY; IMMUNOGLOBULIN G; LIPOCORTIN 5; PHYCOERYTHRIN; THROMBIN; THROMBOCYTE FACTOR 4; AUTOANTIBODY;

ANTIBODY BLOOD LEVEL; ANTIBODY DETECTION; ANTICOAGULATION; ANTIGEN ANTIBODY COMPLEX; BLOOD SAMPLING; C SEROTONIN RELEASE ASSAY; CLINICAL TRIAL (TOPIC); DIAGNOSTIC PROCEDURE; DISSEMINATED INTRAVASCULAR CLOTTING; EDITORIAL; ENZYME IMMUNOASSAY; FLOW CYTOMETRY; HEMODILUTION; HEPARIN INDUCED THROMBOCYTOPENIA; HUMAN; IMMUNIZATION; IMMUNOASSAY; IN VITRO STUDY; OPTICAL DENSITY; PLATELET MICROPARTICLE; PLATELET MICROPARTICLE GENERATION ASSAY; PLATELET REACTIVITY; PRIORITY JOURNAL; QUALITY CONTROL; RADIOACTIVITY; SEPSIS; SEROTONIN RELEASE; THROMBOCYTE ACTIVATION; THROMBOCYTE COUNT; THROMBOCYTOPENIA; ANTIBODY AFFINITY; BLOOD; CHEMICALLY INDUCED; IMMUNOLOGY; MEMBRANE MICROPARTICLE; THROMBOCYTE; ULTRASTRUCTURE;

ANTIBODY AFFINITY; AUTOANTIBODIES; BLOOD PLATELETS; CELL-DERIVED MICROPARTICLES; HEPARIN; HUMANS; THROMBOCYTOPENIA;

EID: 84900465171     PISSN: 00493848     EISSN: 18792472     Source Type: Journal    
DOI: 10.1016/j.thromres.2013.12.040     Document Type: Editorial

References (18)

1. T.E. Warkentin, A. Greinacher, Y. Gruel, R.H. Aster, and B.H. Chong Scientific and Standardization Committee of the International Society on Thrombosis and Haemostasis. Laboratory testing for heparin-induced thrombocytopenia: a conceptual framework and implications for diagnosis J Thromb Haemost 9 2011 2498 2500
2. T.E. Warkentin Heparin-induced thrombocytopenia: pathogenesis and management Br J Haematol 121 2003 535 555
3. T.E. Warkentin Pseudo-heparin-induced thrombocytopenia T.E. Warkentin, A. Greinacher, Heparin-Induced Thrombocytopenia 4th ed. 2007 Informa Healthcare USA, Inc. New York 261 282
4. A. Greinacher, D. Juhl, U. Strobel, A. Wessel, N. Lubenow, and K. Selleng et al. Heparin-induced thrombocytopenia: a prospective study on the incidence, platelet-activating capacity and clinical significance of anti-PF4/heparin antibodies of the IgG, IgM, and IgA classes J Thromb Haemost 5 2007 1666 1673
5. T.E. Warkentin, J.I. Sheppard, J.C. Moore, C.S. Sigouin, and J.G. Kelton Quantitative interpretation of optical density measurements using PF4-dependent enzyme-immunoassays J Thromb Haemost 6 2008 1304 1312
6. T.E. Warkentin How I diagnose and manage HIT Hematology Am Soc Hematol Educ Program 2011 2011 143 149
7. T.E. Warkentin, J.I. Sheppard, J.C. Moore, R.J. Cook, and J.G. Kelton Studies of the immune response in heparin-induced thrombocytopenia Blood 113 2009 4963 4969
8. A. Greinacher, K. Krauel, and I. Jensch HIT-antibodies promote their own antigen Blood 120 2012 930 931
9. B.S. Sachais, R.I. Litvinov, S.V. Yarovoi, L. Rauova, J.L. Hinds, and A.H. Rux et al. Dynamic antibody-binding properties in pathogenesis of HIT Blood 120 2012 1137 1142
10. G.K. Lo, C.S. Sigouin, and T.E. Warkentin What is the potential for overdiagnosis of heparin-induced thrombocytopenia? Am J Hematol 82 2007 1037 1043
11. J. Polgár, P. Eichler, A. Greinacher, and K.J. Clemetson Adenosine diphosphate (ADP) and ADP receptor play a major role in platelet activation/aggregation induced by sera from heparin-induced thrombocytopenia patients Blood 91 1998 549 554
12. A. Greinacher, U. Liebenhoff, V. Kiefel, P. Presek, and C. Mueller-Eckhard Heparin-associated thrombocytopenia: the effects of various intravenous IgG preparations on antibody mediated platelet activation - a possible new indication for high dose i.v. IgG Thromb Haemost 71 1994 641 645
13. K. Krauel, P. Valentin, B. Fürll, E. Hammer, S. Brandt, and I. Jensch et al. Fibronectin inhibits anti-PF4/heparin antibody induced platelet activation and low fibronectin levels are a potential risk factor for developing clinical HIT. ePoster PB 2.40-2 XXIV Congress of the International Society on Thrombosis and Haemostasis, Amsterdam, Netherlands, 2 Jul 2013 Jul 2 2013 [abstract]
14. F. Mullier, V. Minet, N. Bailly, B. Devalet, J. Douxfils, C. Chatelain, I. Elalamy, J.M. Dogné, and B. Chatelain Platelet microparticle generation assay: a valuable test for immune heparin-induced thrombocytopenia diagnosis Thromb Res 133 2014 1068 1073
15. D. Sheridan, C. Carter, and J.G. Kelton A diagnostic test for heparin-induced thrombocytopenia Blood 67 1986 27 30
16. B. Tardy, E. Presles, M. Akrour, E. de Maistre, T. Lecompte, and B. Tardy-Poncet Experts' opinion or the serotonin release assay as the gold standard for the diagnosis of heparin-induced thrombocytopenia (HIT)? J Thromb Haemost 9 2011 1667 1669
17. A. Cuker, P.A. Gimotty, M.A. Crowther, and T.E. Warkentin Predictive value of the 4Ts scoring system for heparin-induced thrombocytopenia: a systematic review and meta-analysis Blood 120 2012 4160 4167
18. T.E. Warkentin, C.P.M. Hayward, C.A. Smith, P.M. Kelly, and J.G. Kelton Determinants of donor platelet variability when testing for heparin-induced thrombocytopenia J Lab Clin Med 120 1992 371 379