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Volumn 5, Issue 3, 2014, Pages 146-160

GPER Mediates Estrogen-Induced Signaling and Proliferation in Human Breast Epithelial Cells and Normal and Malignant Breast

Author keywords

[No Author keywords available]

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR; ESTRADIOL; G PROTEIN COUPLED RECEPTOR 30; HEPARIN; KI 67 ANTIGEN; MATRIX METALLOPROTEINASE; MITOGEN ACTIVATED PROTEIN KINASE; SMALL INTERFERING RNA; ESTROGEN RECEPTOR; G PROTEIN COUPLED RECEPTOR; GPER PROTEIN, HUMAN;

EID: 84900437591     PISSN: 18688497     EISSN: 18688500     Source Type: Journal    
DOI: 10.1007/s12672-014-0174-1     Document Type: Article
Times cited : (88)

References (83)
  • 1
    • 33746668727 scopus 로고    scopus 로고
    • Physiologic estrogen receptor alpha signaling in non-tumorigenic human mammary epithelial cells
    • doi:10.1007/s10549-006-9177-0
    • Abukhdeir AM, Blair BG, Brenner K, Karakas B, Konishi H, Lim J, Sahasranaman V et al (2006) Physiologic estrogen receptor alpha signaling in non-tumorigenic human mammary epithelial cells. Breast Cancer Res Treat 99(1): 23-33. doi: 10. 1007/s10549-006-9177-0.
    • (2006) Breast Cancer Res Treat , vol.99 , Issue.1 , pp. 23-33
    • Abukhdeir, A.M.1    Blair, B.G.2    Brenner, K.3    Karakas, B.4    Konishi, H.5    Lim, J.6    Sahasranaman, V.7
  • 2
    • 33847755409 scopus 로고    scopus 로고
    • G protein-coupled receptor 30 (GPR30) mediates gene expression changes and growth response to 17beta-estradiol and selective GPR30 ligand G-1 in ovarian cancer cells
    • Albanito L, Madeo A, Lappano R, Vivacqua A, Rago V, Carpino A, Oprea TI et al (2007) G protein-coupled receptor 30 (GPR30) mediates gene expression changes and growth response to 17beta-estradiol and selective GPR30 ligand G-1 in ovarian cancer cells. Cancer Res 67(4): 1859-1866.
    • (2007) Cancer Res , vol.67 , Issue.4 , pp. 1859-1866
    • Albanito, L.1    Madeo, A.2    Lappano, R.3    Vivacqua, A.4    Rago, V.5    Carpino, A.6    Oprea, T.I.7
  • 3
    • 77955774697 scopus 로고    scopus 로고
    • GPR30 and estrogen receptor expression: new insights into hormone dependence of inflammatory breast cancer
    • doi:10.1007/s10549-009-0631-7
    • Arias-Pulido H, Royce M, Gong Y, Joste N, Lomo L, Lee SJ, Chaher N et al (2010) GPR30 and estrogen receptor expression: new insights into hormone dependence of inflammatory breast cancer. Breast Cancer Res Treat 123(1): 51-58. doi: 10. 1007/s10549-009-0631-7.
    • (2010) Breast Cancer Res Treat , vol.123 , Issue.1 , pp. 51-58
    • Arias-Pulido, H.1    Royce, M.2    Gong, Y.3    Joste, N.4    Lomo, L.5    Lee, S.J.6    Chaher, N.7
  • 4
    • 76249115409 scopus 로고    scopus 로고
    • The G protein-coupled receptor GPR30 inhibits proliferation of estrogen receptor-positive breast cancer cells
    • Ariazi EA, Brailoiu E, Yerrum S, Shupp HA, Slifker MJ, Cunliffe HE, Black MA et al (2010) The G protein-coupled receptor GPR30 inhibits proliferation of estrogen receptor-positive breast cancer cells. Cancer Res 70(3): 1184-1194.
    • (2010) Cancer Res , vol.70 , Issue.3 , pp. 1184-1194
    • Ariazi, E.A.1    Brailoiu, E.2    Yerrum, S.3    Shupp, H.A.4    Slifker, M.J.5    Cunliffe, H.E.6    Black, M.A.7
  • 5
    • 0035884617 scopus 로고    scopus 로고
    • Differential insulin-like growth factor I receptor signaling and function in estrogen receptor (ER)-positive MCF-7 and ER-negative MDA-MB-231 breast cancer cells
    • Bartucci M, Morelli C, Mauro L, Ando S, Surmacz E (2001) Differential insulin-like growth factor I receptor signaling and function in estrogen receptor (ER)-positive MCF-7 and ER-negative MDA-MB-231 breast cancer cells. Cancer Res 61(18): 6747-6754.
    • (2001) Cancer Res , vol.61 , Issue.18 , pp. 6747-6754
    • Bartucci, M.1    Morelli, C.2    Mauro, L.3    Ando, S.4    Surmacz, E.5
  • 6
    • 0036362083 scopus 로고    scopus 로고
    • Epidemiology of endocrine-related risk factors for breast cancer
    • Bernstein L (2002) Epidemiology of endocrine-related risk factors for breast cancer. J Mammary Gland Biol Neoplasia 7(1): 3-15.
    • (2002) J Mammary Gland Biol Neoplasia , vol.7 , Issue.1 , pp. 3-15
    • Bernstein, L.1
  • 9
    • 0036153461 scopus 로고    scopus 로고
    • Ki67 protein: the immaculate deception?
    • Brown DC, Gatter KC (2002) Ki67 protein: the immaculate deception? Histopathology 40(1): 2-11.
    • (2002) Histopathology , vol.40 , Issue.1 , pp. 2-11
    • Brown, D.C.1    Gatter, K.C.2
  • 10
    • 77951745890 scopus 로고    scopus 로고
    • Estrogen receptor, progesterone receptor, and glucocorticoid receptor expression in normal breast tissue, breast in situ carcinoma, and invasive breast cancer
    • doi:10.1097/PAI.0b013e3181c10180
    • Buxant F, Engohan-Aloghe C, Noel JC (2010) Estrogen receptor, progesterone receptor, and glucocorticoid receptor expression in normal breast tissue, breast in situ carcinoma, and invasive breast cancer. Appl Immunohistochem Mol Morphol 18(3): 254-257. doi: 10. 1097/PAI. 0b013e3181c10180.
    • (2010) Appl Immunohistochem Mol Morphol , vol.18 , Issue.3 , pp. 254-257
    • Buxant, F.1    Engohan-Aloghe, C.2    Noel, J.C.3
  • 11
    • 33748743807 scopus 로고    scopus 로고
    • Impact of estrogen receptor beta on gene networks regulated by estrogen receptor alpha in breast cancer cells
    • Chang EC, Frasor J, Komm B, Katzenellenbogen BS (2006) Impact of estrogen receptor beta on gene networks regulated by estrogen receptor alpha in breast cancer cells. Endocrinology 147(10): 4831-4842.
    • (2006) Endocrinology , vol.147 , Issue.10 , pp. 4831-4842
    • Chang, E.C.1    Frasor, J.2    Komm, B.3    Katzenellenbogen, B.S.4
  • 13
    • 0032867174 scopus 로고    scopus 로고
    • Constitutive overexpression of cyclin D1 in human breast epithelial cells does not prevent G1 arrest induced by deprivation of epidermal growth factor
    • Chou JL, Fan Z, DeBlasio T, Koff A, Rosen N, Mendelsohn J (1999) Constitutive overexpression of cyclin D1 in human breast epithelial cells does not prevent G1 arrest induced by deprivation of epidermal growth factor. Breast Cancer Res Treat 55(3): 267-283.
    • (1999) Breast Cancer Res Treat , vol.55 , Issue.3 , pp. 267-283
    • Chou, J.L.1    Fan, Z.2    DeBlasio, T.3    Koff, A.4    Rosen, N.5    Mendelsohn, J.6
  • 14
    • 0030670385 scopus 로고    scopus 로고
    • Dissociation between steroid receptor expression and cell proliferation in the human breast
    • Clarke RB, Howell A, Potten CS, Anderson E (1997) Dissociation between steroid receptor expression and cell proliferation in the human breast. Cancer Res 57(22): 4987-4991.
    • (1997) Cancer Res , vol.57 , Issue.22 , pp. 4987-4991
    • Clarke, R.B.1    Howell, A.2    Potten, C.S.3    Anderson, E.4
  • 15
    • 0035945656 scopus 로고    scopus 로고
    • Estrogen and the risk of breast cancer
    • doi:10.1056/NEJM200101253440407
    • Clemons M, Goss P (2001) Estrogen and the risk of breast cancer. N Engl J Med 344(4): 276-285. doi: 10. 1056/NEJM200101253440407.
    • (2001) N Engl J Med , vol.344 , Issue.4 , pp. 276-285
    • Clemons, M.1    Goss, P.2
  • 16
    • 0033305438 scopus 로고    scopus 로고
    • Estrogen receptor null mice: what have we learned and where will they lead us?
    • Couse JF, Korach KS (1999) Estrogen receptor null mice: what have we learned and where will they lead us? Endocr Rev 20(3): 358-417.
    • (1999) Endocr Rev , vol.20 , Issue.3 , pp. 358-417
    • Couse, J.F.1    Korach, K.S.2
  • 17
    • 84864387137 scopus 로고    scopus 로고
    • Therapeutic response to CDK4/6 inhibition in breast cancer defined by ex vivo analyses of human tumors
    • doi:10.4161/cc.21195
    • Dean JL, McClendon AK, Hickey TE, Butler LM, Tilley WD, Witkiewicz AK, Knudsen ES (2012) Therapeutic response to CDK4/6 inhibition in breast cancer defined by ex vivo analyses of human tumors. Cell Cycle 11(14): 2756-2761. doi: 10. 4161/cc. 21195.
    • (2012) Cell Cycle , vol.11 , Issue.14 , pp. 2756-2761
    • Dean, J.L.1    McClendon, A.K.2    Hickey, T.E.3    Butler, L.M.4    Tilley, W.D.5    Witkiewicz, A.K.6    Knudsen, E.S.7
  • 18
    • 0037603113 scopus 로고    scopus 로고
    • Morphogenesis and oncogenesis of MCF-10A mammary epithelial acini grown in three-dimensional basement membrane cultures
    • Debnath J, Muthuswamy SK, Brugge JS (2003) Morphogenesis and oncogenesis of MCF-10A mammary epithelial acini grown in three-dimensional basement membrane cultures. Methods 30(3): 256-268.
    • (2003) Methods , vol.30 , Issue.3 , pp. 256-268
    • Debnath, J.1    Muthuswamy, S.K.2    Brugge, J.S.3
  • 21
    • 19644373566 scopus 로고    scopus 로고
    • The membrane-anchoring domain of epidermal growth factor receptor ligands dictates their ability to operate in juxtacrine mode
    • Dong J, Opresko LK, Chrisler W, Orr G, Quesenberry RD, Lauffenburger DA, Wiley HS (2005) The membrane-anchoring domain of epidermal growth factor receptor ligands dictates their ability to operate in juxtacrine mode. Mol Biol Cell 16(6): 2984-2998.
    • (2005) Mol Biol Cell , vol.16 , Issue.6 , pp. 2984-2998
    • Dong, J.1    Opresko, L.K.2    Chrisler, W.3    Orr, G.4    Quesenberry, R.D.5    Lauffenburger, D.A.6    Wiley, H.S.7
  • 22
    • 33750697301 scopus 로고    scopus 로고
    • Effects of estradiol and medroxyprogesterone acetate on morphology, proliferation and apoptosis of human breast tissue in organ cultures
    • Eigeliene N, Harkonen P, Erkkola R (2006) Effects of estradiol and medroxyprogesterone acetate on morphology, proliferation and apoptosis of human breast tissue in organ cultures. BMC Cancer 6: 246.
    • (2006) BMC Cancer , vol.6 , pp. 246
    • Eigeliene, N.1    Harkonen, P.2    Erkkola, R.3
  • 23
    • 0035884620 scopus 로고    scopus 로고
    • Letrozole is more effective neoadjuvant endocrine therapy than tamoxifen for ErbB-1- and/or ErbB-2-positive, estrogen receptor-positive primary breast cancer: evidence from a phase III randomized trial
    • Ellis MJ, Coop A, Singh B, Mauriac L, Llombert-Cussac A, Janicke F, Miller WR et al (2001) Letrozole is more effective neoadjuvant endocrine therapy than tamoxifen for ErbB-1- and/or ErbB-2-positive, estrogen receptor-positive primary breast cancer: evidence from a phase III randomized trial. J Clin Oncol 19(18): 3808-3816.
    • (2001) J Clin Oncol , vol.19 , Issue.18 , pp. 3808-3816
    • Ellis, M.J.1    Coop, A.2    Singh, B.3    Mauriac, L.4    Llombert-Cussac, A.5    Janicke, F.6    Miller, W.R.7
  • 24
    • 73349129405 scopus 로고    scopus 로고
    • Differential induction of apoptosis in HER2 and EGFR addicted cancers following PI3K inhibition
    • Faber AC, Li D, Song Y, Liang MC, Yeap BY, Bronson RT, Lifshits E et al (2009) Differential induction of apoptosis in HER2 and EGFR addicted cancers following PI3K inhibition. Proc Natl Acad Sci U S A 106(46): 19503-19508.
    • (2009) Proc Natl Acad Sci U S A , vol.106 , Issue.46 , pp. 19503-19508
    • Faber, A.C.1    Li, D.2    Song, Y.3    Liang, M.C.4    Yeap, B.Y.5    Bronson, R.T.6    Lifshits, E.7
  • 25
    • 33751272253 scopus 로고    scopus 로고
    • Distribution of GPR30, a seven membrane-spanning estrogen receptor, in primary breast cancer and its association with clinicopathologic determinants of tumor progression
    • Filardo EJ, Graeber CT, Quinn JA, Resnick MB, Giri D, DeLellis RA, Steinhoff MM, Sabo E (2006) Distribution of GPR30, a seven membrane-spanning estrogen receptor, in primary breast cancer and its association with clinicopathologic determinants of tumor progression. Clin Cancer Res 12(21): 6359-6366.
    • (2006) Clin Cancer Res , vol.12 , Issue.21 , pp. 6359-6366
    • Filardo, E.J.1    Graeber, C.T.2    Quinn, J.A.3    Resnick, M.B.4    Giri, D.5    DeLellis, R.A.6    Steinhoff, M.M.7    Sabo, E.8
  • 26
    • 0033780783 scopus 로고    scopus 로고
    • Estrogen-induced activation of Erk-1 and Erk-2 requires the G protein-coupled receptor homolog, GPR30, and occurs via trans-activation of the epidermal growth factor receptor through release of HB-EGF
    • Filardo EJ, Quinn JA, Bland KI, Frackelton AR Jr (2000) Estrogen-induced activation of Erk-1 and Erk-2 requires the G protein-coupled receptor homolog, GPR30, and occurs via trans-activation of the epidermal growth factor receptor through release of HB-EGF. Mol Endocrinol 14(10): 1649-1660.
    • (2000) Mol Endocrinol , vol.14 , Issue.10 , pp. 1649-1660
    • Filardo, E.J.1    Quinn, J.A.2    Bland, K.I.3    Frackelton Jr., A.R.4
  • 28
    • 0345382876 scopus 로고    scopus 로고
    • Involvement of estrogen receptor beta in terminal differentiation of mammary gland epithelium
    • doi:10.1073/pnas.192561299
    • Forster C, Makela S, Warri A, Kietz S, Becker D, Hultenby K, Warner M, Gustafsson JA (2002) Involvement of estrogen receptor beta in terminal differentiation of mammary gland epithelium. Proc Natl Acad Sci U S A 99(24): 15578-15583. doi: 10. 1073/pnas. 192561299.
    • (2002) Proc Natl Acad Sci U S A , vol.99 , Issue.24 , pp. 15578-15583
    • Forster, C.1    Makela, S.2    Warri, A.3    Kietz, S.4    Becker, D.5    Hultenby, K.6    Warner, M.7    Gustafsson, J.A.8
  • 29
    • 46749108373 scopus 로고    scopus 로고
    • ERbeta in breast cancer-onlooker, passive player, or active protector?
    • Fox EM, Davis RJ, Shupnik MA (2008) ERbeta in breast cancer-onlooker, passive player, or active protector? Steroids 73(11): 1039-1051.
    • (2008) Steroids , vol.73 , Issue.11 , pp. 1039-1051
    • Fox, E.M.1    Davis, R.J.2    Shupnik, M.A.3
  • 30
    • 0037150728 scopus 로고    scopus 로고
    • Src in cancer: deregulation and consequences for cell behaviour
    • Frame MC (2002) Src in cancer: deregulation and consequences for cell behaviour. Biochim Biophys Acta 1602(2): 114-130.
    • (2002) Biochim Biophys Acta , vol.1602 , Issue.2 , pp. 114-130
    • Frame, M.C.1
  • 31
    • 0242659957 scopus 로고    scopus 로고
    • Breast cancer tissue estrogens and their manipulation with aromatase inhibitors and inactivators
    • Geisler J (2003) Breast cancer tissue estrogens and their manipulation with aromatase inhibitors and inactivators. J Steroid Biochem Mol Biol 86(3-5): 245-253.
    • (2003) J Steroid Biochem Mol Biol , vol.86 , Issue.3-5 , pp. 245-253
    • Geisler, J.1
  • 32
    • 4544367117 scopus 로고    scopus 로고
    • Towards an integrated model for breast cancer etiology: the lifelong interplay of genes, lifestyle, and hormones
    • doi:10.1186/bcr921
    • Hankinson SE, Colditz GA, Willett WC (2004) Towards an integrated model for breast cancer etiology: the lifelong interplay of genes, lifestyle, and hormones. Breast Cancer Res 6(5): 213-218. doi: 10. 1186/bcr921.
    • (2004) Breast Cancer Res , vol.6 , Issue.5 , pp. 213-218
    • Hankinson, S.E.1    Colditz, G.A.2    Willett, W.C.3
  • 33
    • 27144524273 scopus 로고    scopus 로고
    • Estrogen receptors alfa (ERalpha) and beta (ERbeta) differentially regulate proliferation and apoptosis of the normal murine mammary epithelial cell line HC11
    • Helguero LA, Faulds MH, Gustafsson JA, Haldosen LA (2005) Estrogen receptors alfa (ERalpha) and beta (ERbeta) differentially regulate proliferation and apoptosis of the normal murine mammary epithelial cell line HC11. Oncogene 24(44): 6605-6616.
    • (2005) Oncogene , vol.24 , Issue.44 , pp. 6605-6616
    • Helguero, L.A.1    Faulds, M.H.2    Gustafsson, J.A.3    Haldosen, L.A.4
  • 34
    • 84873468978 scopus 로고    scopus 로고
    • Enhanced expression of G-protein coupled estrogen receptor (GPER/GPR30) in lung cancer
    • doi: 10. 1186/1471-2407-12-624
    • Jala VR, Radde BN, Haribabu B, Klinge CM (2012) Enhanced expression of G-protein coupled estrogen receptor (GPER/GPR30) in lung cancer. BMC Cancer 12: 624. doi: 10. 1186/1471-2407-12-624.
    • (2012) BMC Cancer , vol.12 , pp. 624
    • Jala, V.R.1    Radde, B.N.2    Haribabu, B.3    Klinge, C.M.4
  • 35
    • 28244493099 scopus 로고    scopus 로고
    • Distinct mRNA, protein expression patterns and distribution of oestrogen receptors alpha and beta in human primary breast cancer: correlation with proliferation marker Ki-67 and clinicopathological factors
    • doi:10.1016/j.ejca.2005.09.010
    • Jarzabek K, Koda M, Kozlowski L, Mittre H, Sulkowski S, Kottler ML, Wolczynski S (2005) Distinct mRNA, protein expression patterns and distribution of oestrogen receptors alpha and beta in human primary breast cancer: correlation with proliferation marker Ki-67 and clinicopathological factors. Eur J Cancer 41(18): 2924-2934. doi: 10. 1016/j. ejca. 2005. 09. 010.
    • (2005) Eur J Cancer , vol.41 , Issue.18 , pp. 2924-2934
    • Jarzabek, K.1    Koda, M.2    Kozlowski, L.3    Mittre, H.4    Sulkowski, S.5    Kottler, M.L.6    Wolczynski, S.7
  • 37
    • 77956793023 scopus 로고    scopus 로고
    • G protein-coupled estrogen receptor 1 (GPER, GPR 30) in normal human endometrium and early pregnancy decidua
    • doi:10.1093/molehr/gaq043
    • Kolkova Z, Noskova V, Ehinger A, Hansson S, Casslen B (2010) G protein-coupled estrogen receptor 1 (GPER, GPR 30) in normal human endometrium and early pregnancy decidua. Mol Hum Reprod 16(10): 743-751. doi: 10. 1093/molehr/gaq043.
    • (2010) Mol Hum Reprod , vol.16 , Issue.10 , pp. 743-751
    • Kolkova, Z.1    Noskova, V.2    Ehinger, A.3    Hansson, S.4    Casslen, B.5
  • 38
    • 0028625491 scopus 로고
    • Insights from the study of animals lacking functional estrogen receptor
    • Korach KS (1994) Insights from the study of animals lacking functional estrogen receptor. Science 266(5190): 1524-1527.
    • (1994) Science , vol.266 , Issue.5190 , pp. 1524-1527
    • Korach, K.S.1
  • 39
    • 33646357488 scopus 로고    scopus 로고
    • Src oncogene activates MMP-2 expression via the ERK/Sp1 pathway
    • doi:10.1002/jcp.20616
    • Kuo L, Chang HC, Leu TH, Maa MC, Hung WC (2006) Src oncogene activates MMP-2 expression via the ERK/Sp1 pathway. J Cell Physiol 207(3): 729-734. doi: 10. 1002/jcp. 20616.
    • (2006) J Cell Physiol , vol.207 , Issue.3 , pp. 729-734
    • Kuo, L.1    Chang, H.C.2    Leu, T.H.3    Maa, M.C.4    Hung, W.C.5
  • 40
    • 34547789280 scopus 로고    scopus 로고
    • The interactions between GPR30 and the major biomarkers in infiltrating ductal carcinoma of the breast in an Asian population
    • Kuo WH, Chang LY, Liu DL, Hwa HL, Lin JJ, Lee PH, Chen CN et al (2007) The interactions between GPR30 and the major biomarkers in infiltrating ductal carcinoma of the breast in an Asian population. Taiwan J Obstet Gynecol 46: 135-145.
    • (2007) Taiwan J Obstet Gynecol , vol.46 , pp. 135-145
    • Kuo, W.H.1    Chang, L.Y.2    Liu, D.L.3    Hwa, H.L.4    Lin, J.J.5    Lee, P.H.6    Chen, C.N.7
  • 41
    • 0034868904 scopus 로고    scopus 로고
    • ER beta inhibits proliferation and invasion of breast cancer cells
    • Lazennec G, Bresson D, Lucas A, Chauveau C, Vignon F (2001) ER beta inhibits proliferation and invasion of breast cancer cells. Endocrinology 142(9): 4120-4130.
    • (2001) Endocrinology , vol.142 , Issue.9 , pp. 4120-4130
    • Lazennec, G.1    Bresson, D.2    Lucas, A.3    Chauveau, C.4    Vignon, F.5
  • 42
    • 0036224417 scopus 로고    scopus 로고
    • Cellular functions of plasma membrane estrogen receptors
    • Levin ER (2002) Cellular functions of plasma membrane estrogen receptors. Steroids 67(6): 471-475.
    • (2002) Steroids , vol.67 , Issue.6 , pp. 471-475
    • Levin, E.R.1
  • 43
    • 0037338707 scopus 로고    scopus 로고
    • Bidirectional signaling between the estrogen receptor and the epidermal growth factor receptor
    • doi:10.1210/me.2002-0368
    • Levin ER (2003) Bidirectional signaling between the estrogen receptor and the epidermal growth factor receptor. Mol Endocrinol 17(3): 309-317. doi: 10. 1210/me. 2002-0368.
    • (2003) Mol Endocrinol , vol.17 , Issue.3 , pp. 309-317
    • Levin, E.R.1
  • 44
    • 34250164212 scopus 로고    scopus 로고
    • Inhibitory effects of estrogen receptor beta on specific hormone-responsive gene expression and association with disease outcome in primary breast cancer
    • Lin CY, Strom A, Li Kong S, Kietz S, Thomsen JS, Tee JB, Vega VB et al (2007) Inhibitory effects of estrogen receptor beta on specific hormone-responsive gene expression and association with disease outcome in primary breast cancer. Breast Cancer Res 9(2): R25.
    • (2007) Breast Cancer Res , vol.9 , Issue.2
    • Lin, C.Y.1    Strom, A.2    Li Kong, S.3    Kietz, S.4    Thomsen, J.S.5    Tee, J.B.6    Vega, V.B.7
  • 46
    • 29244446256 scopus 로고    scopus 로고
    • Flow cytometry: a new approach for the molecular profiling of breast cancer
    • Lostumbo A, Mehta D, Setty S, Nunez R (2006) Flow cytometry: a new approach for the molecular profiling of breast cancer. Exp Mol Pathol 80(1): 46-53.
    • (2006) Exp Mol Pathol , vol.80 , Issue.1 , pp. 46-53
    • Lostumbo, A.1    Mehta, D.2    Setty, S.3    Nunez, R.4
  • 47
    • 80054739275 scopus 로고    scopus 로고
    • G-protein coupled estrogen receptor 1 expression in primary breast cancers and its correlation with clinicopathological variables
    • doi:10.4048/jbc.2011.14.3.185
    • Luo HJ, Luo P, Yang GL, Peng QL, Liu MR, Tu G (2011) G-protein coupled estrogen receptor 1 expression in primary breast cancers and its correlation with clinicopathological variables. J Breast Cancer 14(3): 185-190. doi: 10. 4048/jbc. 2011. 14. 3. 185.
    • (2011) J Breast Cancer , vol.14 , Issue.3 , pp. 185-190
    • Luo, H.J.1    Luo, P.2    Yang, G.L.3    Peng, Q.L.4    Liu, M.R.5    Tu, G.6
  • 48
    • 3042547161 scopus 로고    scopus 로고
    • The G protein-coupled receptor GPR30 mediates c-fos up-regulation by 17beta-estradiol and phytoestrogens in breast cancer cells
    • doi:10.1074/jbc.M403588200
    • Maggiolini M, Vivacqua A, Fasanella G, Recchia AG, Sisci D, Pezzi V, Montanaro D, Musti AM, Picard D, Ando S (2004) The G protein-coupled receptor GPR30 mediates c-fos up-regulation by 17beta-estradiol and phytoestrogens in breast cancer cells. J Biol Chem 279(26): 27008-27016. doi: 10. 1074/jbc. M403588200.
    • (2004) J Biol Chem , vol.279 , Issue.26 , pp. 27008-27016
    • Maggiolini, M.1    Vivacqua, A.2    Fasanella, G.3    Recchia, A.G.4    Sisci, D.5    Pezzi, V.6    Montanaro, D.7    Musti, A.M.8    Picard, D.9    Ando, S.10
  • 49
    • 44149084193 scopus 로고    scopus 로고
    • Amphiregulin: role in mammary gland development and breast cancer
    • doi:10.1007/s10911-008-9075-7
    • McBryan J, Howlin J, Napoletano S, Martin F (2008) Amphiregulin: role in mammary gland development and breast cancer. J Mammary Gland Biol Neoplasia 13(2): 159-169. doi: 10. 1007/s10911-008-9075-7.
    • (2008) J Mammary Gland Biol Neoplasia , vol.13 , Issue.2 , pp. 159-169
    • McBryan, J.1    Howlin, J.2    Napoletano, S.3    Martin, F.4
  • 52
    • 34250169073 scopus 로고    scopus 로고
    • Fluorescent substrates for the proteinases ADAM17, ADAM10, ADAM8, and ADAM12 useful for high-throughput inhibitor screening
    • Moss ML, Rasmussen FH (2007) Fluorescent substrates for the proteinases ADAM17, ADAM10, ADAM8, and ADAM12 useful for high-throughput inhibitor screening. Anal Biochem 366(2): 144-148.
    • (2007) Anal Biochem , vol.366 , Issue.2 , pp. 144-148
    • Moss, M.L.1    Rasmussen, F.H.2
  • 53
    • 0026747170 scopus 로고
    • Expression cloning of a diphtheria toxin receptor: identity with a heparin-binding EGF-like growth factor precursor
    • Naglich JG, Metherall JE, Russell DW, Eidels L (1992) Expression cloning of a diphtheria toxin receptor: identity with a heparin-binding EGF-like growth factor precursor. Cell 69(6): 1051-1061.
    • (1992) Cell , vol.69 , Issue.6 , pp. 1051-1061
    • Naglich, J.G.1    Metherall, J.E.2    Russell, D.W.3    Eidels, L.4
  • 54
    • 66749105045 scopus 로고    scopus 로고
    • Nuclear receptors: genomic and non-genomic effects converge
    • Ordonez-Moran P, Munoz A (2009) Nuclear receptors: genomic and non-genomic effects converge. Cell Cycle 8(11): 1675-1680.
    • (2009) Cell Cycle , vol.8 , Issue.11 , pp. 1675-1680
    • Ordonez-Moran, P.1    Munoz, A.2
  • 56
    • 53249107839 scopus 로고    scopus 로고
    • G protein-coupled receptor 30 localizes to the endoplasmic reticulum and is not activated by estradiol
    • Otto C, Rohde-Schulz B, Schwarz G, Fuchs I, Klewer M, Brittain D, Langer G et al (2008) G protein-coupled receptor 30 localizes to the endoplasmic reticulum and is not activated by estradiol. Endocrinology 149(10): 4846-4856.
    • (2008) Endocrinology , vol.149 , Issue.10 , pp. 4846-4856
    • Otto, C.1    Rohde-Schulz, B.2    Schwarz, G.3    Fuchs, I.4    Klewer, M.5    Brittain, D.6    Langer, G.7
  • 57
    • 62049084027 scopus 로고    scopus 로고
    • Estrogenic GPR30 signalling induces proliferation and migration of breast cancer cells through CTGF
    • Pandey DP, Lappano R, Albanito L, Madeo A, Maggiolini M, Picard D (2009) Estrogenic GPR30 signalling induces proliferation and migration of breast cancer cells through CTGF. EMBO J 28(5): 523-532.
    • (2009) EMBO J , vol.28 , Issue.5 , pp. 523-532
    • Pandey, D.P.1    Lappano, R.2    Albanito, L.3    Madeo, A.4    Maggiolini, M.5    Picard, D.6
  • 58
    • 1642535535 scopus 로고    scopus 로고
    • Estrogen receptor beta inhibits human breast cancer cell proliferation and tumor formation by causing a G2 cell cycle arrest
    • Paruthiyil S, Parmar H, Kerekatte V, Cunha GR, Firestone GL, Leitman DC (2004) Estrogen receptor beta inhibits human breast cancer cell proliferation and tumor formation by causing a G2 cell cycle arrest. Cancer Res 64(1): 423-428.
    • (2004) Cancer Res , vol.64 , Issue.1 , pp. 423-428
    • Paruthiyil, S.1    Parmar, H.2    Kerekatte, V.3    Cunha, G.R.4    Firestone, G.L.5    Leitman, D.C.6
  • 59
    • 33747841976 scopus 로고    scopus 로고
    • Nature of functional estrogen receptors at the plasma membrane
    • Pedram A, Razandi M, Levin ER (2006) Nature of functional estrogen receptors at the plasma membrane. Mol Endocrinol 20(9): 1996-2009.
    • (2006) Mol Endocrinol , vol.20 , Issue.9 , pp. 1996-2009
    • Pedram, A.1    Razandi, M.2    Levin, E.R.3
  • 60
    • 0027304028 scopus 로고
    • Estrogens, progestogens, normal breast cell proliferation, and breast cancer risk
    • Pike MC, Spicer DV, Dahmoush L, Press MF (1993) Estrogens, progestogens, normal breast cell proliferation, and breast cancer risk. Epidemiol Rev 15(1): 17-35.
    • (1993) Epidemiol Rev , vol.15 , Issue.1 , pp. 17-35
    • Pike, M.C.1    Spicer, D.V.2    Dahmoush, L.3    Press, M.F.4
  • 61
    • 0030031578 scopus 로고    scopus 로고
    • Characterization of the estrogen receptor transfected MCF10A breast cell line 139B6
    • Pilat MJ, Christman JK, Brooks SC (1996) Characterization of the estrogen receptor transfected MCF10A breast cell line 139B6. Breast Cancer Res Treat 37(3): 253-266.
    • (1996) Breast Cancer Res Treat , vol.37 , Issue.3 , pp. 253-266
    • Pilat, M.J.1    Christman, J.K.2    Brooks, S.C.3
  • 62
    • 0037462733 scopus 로고    scopus 로고
    • Proximal events in signaling by plasma membrane estrogen receptors
    • doi:10.1074/jbc.M205692200
    • Razandi M, Pedram A, Park ST, Levin ER (2003) Proximal events in signaling by plasma membrane estrogen receptors. J Biol Chem 278(4): 2701-2712. doi: 10. 1074/jbc. M205692200.
    • (2003) J Biol Chem , vol.278 , Issue.4 , pp. 2701-2712
    • Razandi, M.1    Pedram, A.2    Park, S.T.3    Levin, E.R.4
  • 63
    • 14844343093 scopus 로고    scopus 로고
    • A transmembrane intracellular estrogen receptor mediates rapid cell signaling
    • Revankar CM, Cimino DF, Sklar LA, Arterburn JB, Prossnitz ER (2005) A transmembrane intracellular estrogen receptor mediates rapid cell signaling. Science 307(5715): 1625-1630.
    • (2005) Science , vol.307 , Issue.5715 , pp. 1625-1630
    • Revankar, C.M.1    Cimino, D.F.2    Sklar, L.A.3    Arterburn, J.B.4    Prossnitz, E.R.5
  • 64
    • 0035726693 scopus 로고    scopus 로고
    • G-protein-coupled receptor dimerization: modulation of receptor function
    • Rios CD, Jordan BA, Gomes I, Devi LA (2001) G-protein-coupled receptor dimerization: modulation of receptor function. Pharmacol Ther 92(2-3): 71-87.
    • (2001) Pharmacol Ther , vol.92 , Issue.2-3 , pp. 71-87
    • Rios, C.D.1    Jordan, B.A.2    Gomes, I.3    Devi, L.A.4
  • 65
    • 79951987933 scopus 로고    scopus 로고
    • G protein-coupled estrogen receptor 1/G protein-coupled receptor 30 localizes in the plasma membrane and traffics intracellularly on cytokeratin intermediate filaments
    • Sanden C, Broselid S, Cornmark L, Andersson K, Daszkiewicz-Nilsson J, Martensson UE, Olde B, Leeb-Lundberg LM (2011) G protein-coupled estrogen receptor 1/G protein-coupled receptor 30 localizes in the plasma membrane and traffics intracellularly on cytokeratin intermediate filaments. Mol Pharmacol 79(3): 400-410.
    • (2011) Mol Pharmacol , vol.79 , Issue.3 , pp. 400-410
    • Sanden, C.1    Broselid, S.2    Cornmark, L.3    Andersson, K.4    Daszkiewicz-Nilsson, J.5    Martensson, U.E.6    Olde, B.7    Leeb-Lundberg, L.M.8
  • 66
    • 79960705272 scopus 로고    scopus 로고
    • Mechanisms of estradiol-induced insulin secretion by the G protein-coupled estrogen receptor GPR30/GPER in pancreatic beta-cells
    • Sharma G, Prossnitz ER (2011) Mechanisms of estradiol-induced insulin secretion by the G protein-coupled estrogen receptor GPR30/GPER in pancreatic beta-cells. Endocrinology 152(8): 3030-3039.
    • (2011) Endocrinology , vol.152 , Issue.8 , pp. 3030-3039
    • Sharma, G.1    Prossnitz, E.R.2
  • 68
    • 0031727149 scopus 로고    scopus 로고
    • The activation of ProMMP-2 (gelatinase A) by HT1080 fibrosarcoma cells is promoted by culture on a fibronectin substrate and is concomitant with an increase in processing of MT1-MMP (MMP-14) to a 45 kDa form
    • Stanton H, Gavrilovic J, Atkinson SJ, d'Ortho MP, Yamada KM, Zardi L, Murphy G (1998) The activation of ProMMP-2 (gelatinase A) by HT1080 fibrosarcoma cells is promoted by culture on a fibronectin substrate and is concomitant with an increase in processing of MT1-MMP (MMP-14) to a 45 kDa form. J Cell Sci 111(Pt 18): 2789-2798.
    • (1998) J Cell Sci , vol.111 , Issue.Pt 18 , pp. 2789-2798
    • Stanton, H.1    Gavrilovic, J.2    Atkinson, S.J.3    d'Ortho, M.P.4    Yamada, K.M.5    Zardi, L.6    Murphy, G.7
  • 70
    • 0030712331 scopus 로고    scopus 로고
    • The membrane-bound form of heparin-binding epidermal growth factor-like growth factor promotes survival of cultured renal epithelial cells
    • Takemura T, Kondo S, Homma T, Sakai M, Harris RC (1997) The membrane-bound form of heparin-binding epidermal growth factor-like growth factor promotes survival of cultured renal epithelial cells. J Biol Chem 272(49): 31036-31042.
    • (1997) J Biol Chem , vol.272 , Issue.49 , pp. 31036-31042
    • Takemura, T.1    Kondo, S.2    Homma, T.3    Sakai, M.4    Harris, R.C.5
  • 71
    • 60549117173 scopus 로고    scopus 로고
    • Autocrine regulation of cell proliferation by estrogen receptor-alpha in estrogen receptor-alpha-positive breast cancer cell lines
    • Tan H, Zhong Y, Pan Z (2009) Autocrine regulation of cell proliferation by estrogen receptor-alpha in estrogen receptor-alpha-positive breast cancer cell lines. BMC Cancer 9: 31.
    • (2009) BMC Cancer , vol.9 , pp. 31
    • Tan, H.1    Zhong, Y.2    Pan, Z.3
  • 72
    • 12344307170 scopus 로고    scopus 로고
    • Identity of an estrogen membrane receptor coupled to a G protein in human breast cancer cells
    • Thomas P, Pang Y, Filardo EJ, Dong J (2005) Identity of an estrogen membrane receptor coupled to a G protein in human breast cancer cells. Endocrinology 146(2): 624-632.
    • (2005) Endocrinology , vol.146 , Issue.2 , pp. 624-632
    • Thomas, P.1    Pang, Y.2    Filardo, E.J.3    Dong, J.4
  • 73
    • 77950858531 scopus 로고    scopus 로고
    • Estrogen receptor beta exerts growth-inhibitory effects on human mammary epithelial cells
    • doi: 10. 1007/s10549-009-0413-2
    • Treeck O, Lattrich C, Springwald A, Ortmann O (2010) Estrogen receptor beta exerts growth-inhibitory effects on human mammary epithelial cells. Breast Cancer Res Treat 120(3): 557-565. doi: 10. 1007/s10549-009-0413-2.
    • (2010) Breast Cancer Res Treat , vol.120 , Issue.3 , pp. 557-565
    • Treeck, O.1    Lattrich, C.2    Springwald, A.3    Ortmann, O.4
  • 74
    • 33344461590 scopus 로고    scopus 로고
    • The G protein-coupled receptor GPR30 mediates the proliferative effects induced by 17beta-estradiol and hydroxytamoxifen in endometrial cancer cells
    • Vivacqua A, Bonofiglio D, Recchia AG, Musti AM, Picard D, Ando S, Maggiolini M (2006) The G protein-coupled receptor GPR30 mediates the proliferative effects induced by 17beta-estradiol and hydroxytamoxifen in endometrial cancer cells. Mol Endocrinol 20(3): 631-646.
    • (2006) Mol Endocrinol , vol.20 , Issue.3 , pp. 631-646
    • Vivacqua, A.1    Bonofiglio, D.2    Recchia, A.G.3    Musti, A.M.4    Picard, D.5    Ando, S.6    Maggiolini, M.7
  • 75
    • 33745160700 scopus 로고    scopus 로고
    • A variant of estrogen receptor-{alpha}, hER-{alpha}36: transduction of estrogen- and antiestrogen-dependent membrane-initiated mitogenic signaling
    • doi:10.1073/pnas.0603339103
    • Wang Z, Zhang X, Shen P, Loggie BW, Chang Y, Deuel TF (2006) A variant of estrogen receptor-{alpha}, hER-{alpha}36: transduction of estrogen- and antiestrogen-dependent membrane-initiated mitogenic signaling. Proc Natl Acad Sci U S A 103(24): 9063-9068. doi: 10. 1073/pnas. 0603339103.
    • (2006) Proc Natl Acad Sci U S A , vol.103 , Issue.24 , pp. 9063-9068
    • Wang, Z.1    Zhang, X.2    Shen, P.3    Loggie, B.W.4    Chang, Y.5    Deuel, T.F.6
  • 76
    • 0032560517 scopus 로고    scopus 로고
    • Phosphorylation of histone H3 at serine 10 is correlated with chromosome condensation during mitosis and meiosis in Tetrahymena
    • Wei Y, Mizzen CA, Cook RG, Gorovsky MA, Allis CD (1998) Phosphorylation of histone H3 at serine 10 is correlated with chromosome condensation during mitosis and meiosis in Tetrahymena. Proc Natl Acad Sci U S A 95(13): 7480-7484.
    • (1998) Proc Natl Acad Sci U S A , vol.95 , Issue.13 , pp. 7480-7484
    • Wei, Y.1    Mizzen, C.A.2    Cook, R.G.3    Gorovsky, M.A.4    Allis, C.D.5
  • 77
    • 38949182981 scopus 로고    scopus 로고
    • A genome-wide study of the repressive effects of estrogen receptor beta on estrogen receptor alpha signaling in breast cancer cells
    • Williams C, Edvardsson K, Lewandowski SA, Strom A, Gustafsson JA (2008) A genome-wide study of the repressive effects of estrogen receptor beta on estrogen receptor alpha signaling in breast cancer cells. Oncogene 27(7): 1019-1032.
    • (2008) Oncogene , vol.27 , Issue.7 , pp. 1019-1032
    • Williams, C.1    Edvardsson, K.2    Lewandowski, S.A.3    Strom, A.4    Gustafsson, J.A.5
  • 78
    • 33845978786 scopus 로고    scopus 로고
    • Autocrine and juxtacrine effects of amphiregulin on the proliferative, invasive, and migratory properties of normal and neoplastic human mammary epithelial cells
    • Willmarth NE, Ethier SP (2006) Autocrine and juxtacrine effects of amphiregulin on the proliferative, invasive, and migratory properties of normal and neoplastic human mammary epithelial cells. J Biol Chem 281(49): 37728-37737.
    • (2006) J Biol Chem , vol.281 , Issue.49 , pp. 37728-37737
    • Willmarth, N.E.1    Ethier, S.P.2
  • 79
    • 30944469849 scopus 로고    scopus 로고
    • Estrogen carcinogenesis in breast cancer
    • Yager JD, Davidson NE (2006) Estrogen carcinogenesis in breast cancer. N Engl J Med 354(3): 270-282.
    • (2006) N Engl J Med , vol.354 , Issue.3 , pp. 270-282
    • Yager, J.D.1    Davidson, N.E.2
  • 80
    • 0034066141 scopus 로고    scopus 로고
    • Antitumor action of physiological estradiol on tamoxifen-stimulated breast tumors grown in athymic mice
    • Yao K, Lee ES, Bentrem DJ, England G, Schafer JI, O'Regan RM, Jordan VC (2000) Antitumor action of physiological estradiol on tamoxifen-stimulated breast tumors grown in athymic mice. Clin Cancer Res 6(5): 2028-2036.
    • (2000) Clin Cancer Res , vol.6 , Issue.5 , pp. 2028-2036
    • Yao, K.1    Lee, E.S.2    Bentrem, D.J.3    England, G.4    Schafer, J.I.5    O'Regan, R.M.6    Jordan, V.C.7
  • 81
    • 0347997608 scopus 로고    scopus 로고
    • MAPK signal pathways in the regulation of cell proliferation in mammalian cells
    • doi:10.1038/sj.cr.7290105
    • Zhang W, Liu HT (2002) MAPK signal pathways in the regulation of cell proliferation in mammalian cells. Cell Res 12(1): 9-18. doi: 10. 1038/sj. cr. 7290105.
    • (2002) Cell Res , vol.12 , Issue.1 , pp. 9-18
    • Zhang, W.1    Liu, H.T.2
  • 82
    • 84856024073 scopus 로고    scopus 로고
    • Estrogen receptor-alpha 36 mediates mitogenic antiestrogen signaling in ER-negative breast cancer cells
    • doi:10.1371/journal.pone.0030174
    • Zhang X, Ding L, Kang L, Wang ZY (2012) Estrogen receptor-alpha 36 mediates mitogenic antiestrogen signaling in ER-negative breast cancer cells. PLoS One 7(1): e30174. doi: 10. 1371/journal. pone. 0030174.
    • (2012) PLoS One , vol.7 , Issue.1
    • Zhang, X.1    Ding, L.2    Kang, L.3    Wang, Z.Y.4
  • 83
    • 33845950849 scopus 로고    scopus 로고
    • Inhibition of EGFR/PI3K/AKT cell survival pathway promotes TSA's effect on cell death and migration in human ovarian cancer cells
    • Zhou C, Qiu L, Sun Y, Healey S, Wanebo H, Kouttab N, Di W, Yan B, Wan Y (2006) Inhibition of EGFR/PI3K/AKT cell survival pathway promotes TSA's effect on cell death and migration in human ovarian cancer cells. Int J Oncol 29(1): 269-278.
    • (2006) Int J Oncol , vol.29 , Issue.1 , pp. 269-278
    • Zhou, C.1    Qiu, L.2    Sun, Y.3    Healey, S.4    Wanebo, H.5    Kouttab, N.6    Di, W.7    Yan, B.8    Wan, Y.9


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