Estrogen receptor, progesterone receptor, and glucocorticoid receptor expression in normal breast tissue, breast in situ carcinoma, and invasive breast cancer

Applied Immunohistochemistry and Molecular Morphology

Volumn 18, Issue 3, 2010, Pages 254-257

  Buxant, Frederic ^a   Engohan Aloghe, Corine ^a   Noël, Jean Christophe ^a  

^a ERASME HOSPITAL   (Belgium)

Author keywords

DIN and invasive carcinoma; ER; PR and GR expression in normal breast

Indexed keywords

ESTROGEN RECEPTOR; GLUCOCORTICOID RECEPTOR; PROGESTERONE RECEPTOR; SULFOTRANSFERASE;

ARTICLE; BREAST CARCINOMA; CANCER GRADING; CANCER INVASION; CONTROLLED STUDY; ENZYME ACTIVITY; HUMAN; INTRADUCTAL CARCINOMA; MAJOR CLINICAL STUDY; PRIORITY JOURNAL; PROTEIN EXPRESSION;

BREAST; BREAST NEOPLASMS; CARCINOMA, DUCTAL; DISEASE PROGRESSION; FEMALE; HUMANS; IMMUNOHISTOCHEMISTRY; NEOPLASM METASTASIS; NEOPLASM STAGING; RECEPTORS, ESTROGEN; RECEPTORS, GLUCOCORTICOID; RECEPTORS, PROGESTERONE;

EID: 77951745890     PISSN: 15412016     EISSN: 15334058     Source Type: Journal    
DOI: 10.1097/PAI.0b013e3181c10180     Document Type: Article

References (29)

1. Warr D. Standard treatment of chemotherapy-induced emesis. Support Care Cancer. 1997;5:12-16.
2. Kofler R. The molecular basis of glucocorticoid-induced apoptosis of lymphoblastic leukemia cells. Histochem Cell Biol. 2000;114:1-7.
3. Evans-Storms RB, Cidlowski JA. Delineation of an antiapoptotic action of glucocorticoids in hepatoma cells: the role of nuclear factor-kB. Endocrinology. 2000;141:1854-1862.
4. Zhang C, Beckermann B, Kallifatidis G, et al. Corticosteroids induce chemotherapy resistance in the majority of tumour cells from bone, brain, breast, cervix, melanoma and neuroblastoma. Int J Oncol. 2006;29:1295-1301.
5. Herr I, Ucur E, Herzer K, et al. Glucocorticoid cotreatment induces apoptosis resistance toward cancer therapy in carcinomas. Cancer Res. 2003;63:3112-3120.
6. Moutsatsou P, Papavassiliou AG. The glucocorticoid receptor signaling in breast cancer. J Cell Mol Med. 2008;12:145-163.
7. Beato M, Herrlich P, Schütz G. Steroid hormone receptors: many actors in search of a plot. Cell. 1995;83:851-857.
8. Galon J, Franchimont D, Hiroi N, et al. Gene profiling reveals unknown enhancing and suppressive actions of glucocorticoids on immune cells. FASEB J. 2002;16:61-71.
9. Kino T, DeMartinoMU, Charmandari E, et al. Tissue glucocorticoid resistance/hypersensitivity syndromes. J Steroid Biochem Mol Biol. 2003;85:457-467.
10. Conde I, Paniagua R, Fraile B, et al. Glucocorticoid receptor changes its cellular location with breast cancer development. Histol Histopathol. 2008;23:77-85.
11. Lien HC, Lu YS, Cheng AL, et al. Differential expression of glucocorticoid receptor in human breast tissues and related neoplasms. J Pathol. 2006;209:317-327.
12. Belova L, Delgado B, Kocherginsky M, et al. Glucocorticoid receptor expression in breast cancer associates with older patient age. Breast Cancer Res Treat. 2009;116:441-447.
13. Wintermantel TM, Bock D, Fleig V, et al. The epithelial glucocorticoid receptor is required for the normal timing of cell proliferation during mammary lobuloalveolar development but is dispensable for milk production. Mol Endocrinol. 2005;19:340-349.
14. Gong H, Jarzynka MJ, Cole TJ, et al. Glucocorticoids antagonize estrogens by glucocorticoid receptor-mediated activation of estrogen sulfotransferase. Cancer Res. 2008;68:7386-7393.
15. Goswami B, Rajappa M, Sharma M, et al. Inflammation: its role and interplay in the development of cancer, with special focus on gynecological malignancies. Int J Gynecol Cancer. 2008;18:591-599.
16. Honorat M, Mesnier A, Di Pietro A, et al. Dexamethasone downregulates ABCG2 expression levels in breast cancer cells. Biochem Biophys Res Commun. 2008;375:308-314.
17. Ouatas T, Halverson D, Steeg PS. Dexamethasone and medroxyprogesterone acetate elevate Nm23-H1 metastasis suppressor gene expression in metastatic human breast carcinoma cells: new uses for old compounds. Clin Cancer Res. 2003;9:3763-3772.
18. Tavassoli FA, Eusebi V. Atlas of Tumor Pathology. Mammary Gland. Washington, DC: The Armed Forces Institute of Pathology (AFIP); 2009. in press.
19. Haid M. Steroid antiemesis may be harmful. N Engl J Med. 1981; 304:1237.
20. Rutz HP. Effects of corticosteroid use on treatment of solid tumours. Lancet. 2002;360:1969-1970.
21. Sherlock P, Hartmann WH. Adrenal steroids and the pattern of metastases of breast cancer. JAMA. 1962;181:313-317.
22. Sapi E, Flick MB, Gilmore-Hebert M, et al. Transcriptional regulation of the c-fms (CSF-1R) proto-oncogene in human breast carcinoma cells by glucocorticoids. Oncogene. 1995;10:529-542.
23. Filderman AE, Bruckner A, Kacinski BM, et al. Macrophage colonystimulating factor (CSF-1) enhances invasiveness in CSF-1 receptorpositive carcinoma cell lines. Cancer Res. 1992;52:3661-3666.
24. Rutz HP, Herr I. Interference of glucocorticoids with apoptosis signaling and host-tumor interactions. Cancer Biol Ther. 2004; 3:715-718.
25. Herr I, Gassler N, Friess H, et al. Regulation of differential proand anti-apoptotic signalling by glucocorticoids. Apoptosis. 2007;12: 271-291.
26. Freije JM, MacDonald NJ, Steeg PS. Nm23 and tumour metastasis: basic and translational advances. Biochem Soc Symp. 1998;63:261-271.
27. Fazekas AG, MacFarlane JK. Macromolecular binding of glucocorticoids in human mammary carcinoma. Cancer Res. 1977;37: 640-645.
28. Ioannidis C, Papamichail M, Agnanti N, et al. The detection of glucocorticoid receptors in breast cancer by immunocytochemical and biochemical methods. Int J Cancer. 1982;29:147-152.
29. Smith RA, Lea RA, Curran JE, et al. Expression of glucocorticoid and progesterone nuclear receptor genes in archival breast cancer tissue. Breast Cancer Res. 2003;5:R9-R12.