Inhibiting heat shock factor 1 in human cancer cells with a potent RNA aptamer

PLoS ONE

Volumn 9, Issue 5, 2014, Pages

  Salamanca, H Hans ^a,b   Antonyak, Marc A ^a   Cerione, Richard A ^a   Shi, Hua ^c   Lis, John T ^a,d  

^a Department of Obstetrics Gynecology   (United States)

^b State University of New York Upstate Medical University: College of Medicine   (United States)

^c STATE UNIVERSITY OF NEW YORK   (United States)

^d Dongguk University   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; HEAT SHOCK TRANSCRIPTION FACTOR 1; MITOGEN ACTIVATED PROTEIN KINASE; RNA APTAMER; UNCLASSIFIED DRUG; APTAMER; DNA BINDING PROTEIN; HEAT SHOCK TRANSCRIPTION FACTOR; RNA; TRANSCRIPTION FACTOR;

ANTINEOPLASTIC ACTIVITY; ARTICLE; BINDING AFFINITY; BINDING SITE; CANCER CELL LINE; CANCER INHIBITION; CELL LEVEL; CELL TRANSFORMATION; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; DRUG POTENCY; ENZYME INHIBITION; GENE EXPRESSION; GENE FUNCTION; GENE IDENTIFICATION; HUMAN; HUMAN CELL; MOLECULAR DYNAMICS; ONCOGENE; PHENOTYPE; PROMOTER REGION; PROTEIN DETERMINATION; PROTEIN DNA BINDING; PROTEIN EXPRESSION; PROTEIN FUNCTION; SIGNAL TRANSDUCTION; ANTAGONISTS AND INHIBITORS; APOPTOSIS; GENETICS; HEAT; HEAT SHOCK RESPONSE; HEK293 CELL LINE; HELA CELL LINE; MCF 7 CELL LINE; METABOLISM; TUMOR CELL LINE;

APOPTOSIS; APTAMERS, NUCLEOTIDE; CELL LINE, TUMOR; DNA-BINDING PROTEINS; HEAT-SHOCK RESPONSE; HEK293 CELLS; HELA CELLS; HOT TEMPERATURE; HUMANS; MCF-7 CELLS; MITOGEN-ACTIVATED PROTEIN KINASES; PROMOTER REGIONS, GENETIC; RNA; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTORS;

EID: 84900434881     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0096330     Document Type: Article

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