Effect of hypoxic stress on migration and characteristics of monocytes in uveal melanoma

JAMA Ophthalmology

Volumn 132, Issue 5, 2014, Pages 614-621

  Bronkhorst, Inge H G ^a   Jehs, Tina M L ^b   Dijkgraaf, Eveline M ^a   Luyten, Gregorius P M ^a   Van Der Velden, Pieter A ^a   Van Der Burg, Sjoerd H ^a   Jager, Martine J ^a  

^a LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^b UNIVERSITY OF COPENHAGEN   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 6; MACROPHAGE DERIVED CHEMOKINE; PROSTAGLANDIN E2; TRANSFORMING GROWTH FACTOR BETA;

ARTICLE; CANCER CELL CULTURE; CELL DIFFERENTIATION ASSAY; CELL MIGRATION; CELL MIGRATION ASSAY; CHEMOTAXIS; ENZYME LINKED IMMUNOSORBENT ASSAY; HYPOXIA; IMMUNE RESPONSE GENE; IN VITRO STUDY; MACROPHAGE; MELANOMA CELL; MONOCYTE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; SUPERNATANT; TUMOR SUPERNATANT; UVEA MELANOMA;

ANOXIA; CELL MOVEMENT; CYTOKINES; DNA, NEOPLASM; ENZYME-LINKED IMMUNOSORBENT ASSAY; FLOW CYTOMETRY; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; MELANOMA; MONOCYTES; OXIDATIVE STRESS; POLYMERASE CHAIN REACTION; TUMOR CELLS, CULTURED; UVEAL NEOPLASMS;

EID: 84900422335     PISSN: 21686165     EISSN: None     Source Type: Journal    
DOI: 10.1001/jamaophthalmol.2014.43     Document Type: Article

References (32)

1. Carreau A, El Hafny-Rahbi B, Matejuk A, Grillon C, Kieda C. Why is the partial oxygen pressure of human tissues a crucial parameter? small molecules and hypoxia. J Cell Mol Med. 2011;15(6):1239-1253.
2. Ke Q, Costa M. Hypoxia-inducible factor-1 (HIF-1). Mol Pharmacol. 2006;70(5):1469-1480.
3. Zimmerman LE, McLean IW, FosterWD. Does enucleation of the eye containing a malignant melanoma prevent or accelerate the dissemination of tumour cells? Br J Ophthalmol. 1978;62(6):420-425.
4. Gass JD. Comparison of uveal melanoma growth rates with mitotic index and mortality. Arch Ophthalmol. 1985;103(7):924-931.
5. Burnier MN, McLean IW, Zimmerman LE, Rosenberg SH. Retinoblastoma: the relationship of proliferating cells to blood vessels. Invest Ophthalmol Vis Sci. 1990;31(10):2037-2040.
6. Victor N, Ivy A, Jiang BH, Agani FH. Involvement of HIF-1 in invasion of Mum2B uveal melanoma cells. Clin ExpMetastasis. 2006;23(1):87-96.
7. Chang SH,Worley LA, Onken MD, Harbour JW. Prognostic biomarkers in uveal melanoma: evidence for a stem cell-like phenotype associated with metastasis. Melanoma Res. 2008;18(3): 191-200.
8. Chan DA, Giaccia AJ. Hypoxia, gene expression, and metastasis. Cancer Metastasis Rev. 2007;26(2):333-339.
9. Chen PW, Ksander BR. Influence of immune surveillance and immune privilege on formation of intraocular tumors. Chem Immunol Allergy. 2007;92:276-289.
10. Niederkorn JY,Wang S. Immunology of intraocular tumors. Ocul Immunol Inflamm. 2005;13(1):105-110.
11. Landreville S, Agapova OA, Harbour JW. Emerging insights into the molecular pathogenesis of uveal melanoma. Future Oncol. 2008;4(5):629-636.
12. Giatromanolaki A, Sivridis E, Bechrakis NE, et al. Phosphorylated pVEGFR2/KDR receptor expression in uveal melanomas: relation with HIF2a and survival. Clin ExpMetastasis. 2012;29(1):11-17.
13. Talmadge JE. Immune cell infiltration of primary and metastatic lesions: mechanisms and clinical impact. Semin Cancer Biol. 2011;21(2):131-138.
14. Mantovani A, Allavena P, Sozzani S, Vecchi A, LocatiM, Sica A. Chemokines in the recruitment and shaping of the leukocyte infiltrate of tumors. Semin Cancer Biol. 2004;14(3):155-160.
15. Mantovani A, Schioppa T, Porta C, Allavena P, Sica A. Role of tumor-Associated macrophages in tumor progression and invasion. Cancer Metastasis Rev. 2006;25(3):315-322.
16. Hiscox S, Barrett-Lee P, Nicholson RI. Therapeutic targeting of tumor-stroma interactions. Expert Opin Ther Targets. 2011;15(5):609-621.
17. Makitie T, Summanen P, Tarkkanen A, Kivela T. Tumor-infiltrating macrophages (CD68(+) cells) and prognosis in malignant uveal melanoma. Invest Ophthalmol Vis Sci. 2001;42(7):1414-1421.
18. Bronkhorst IH, Ly LV, Jordanova ES, et al. Detection ofM2-macrophages in uveal melanoma and relation with survival. Invest Ophthalmol Vis Sci. 2011;52(2):643-650.
19. Murdoch C, Muthana M, Coffelt SB, Lewis CE. The role ofmyeloid cells in the promotion of tumour angiogenesis. Nat Rev Cancer. 2008;8(8):618-631.
20. Singh AD, Shields CL, Shields JA. Prognostic factors in uveal melanoma. Melanoma Res. 2001;11(3):255-263.
21. el Filali M, Missotten GS, MaatW, et al. Regulation of VEGF-A in uveal melanoma. Invest Ophthalmol Vis Sci. 2010;51(5):2329-2337.
22. El Filali M, Homminga I, MaatW, van der Velden PA, Jager MJ. Triamcinolone acetonide and anecortave acetate do not stimulate uveal melanoma cell growth. Mol Vis. 2008;14:1752-1759.
23. Goossens K, Van PouckeM, Van Soom A, Vandesompele J, Van Zeveren A, Peelman LJ. Selection of reference genes for quantitative real-time PCR in bovine preimplantation embryos. BMC Dev Biol. 2005;5:27.
24. Vandesompele J, De Preter K, Pattyn F, et al Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes. Genome Biol. 2002;3(7):research0034. doi:10.1186/gb-2002-3-7- research0034.
25. HeusinkveldM, de Vos van Steenwijk PJ, Goedemans R, et al.M2 macrophages induced by prostaglandin E2 and IL-6 from cervical carcinoma are switched to activated M1 macrophages by CD4+ Th1 cells. J Immunol. 2011;187(3):1157-1165.
26. Wilczynski J, Duechler M, CzyzM. Targeting NF-B and HIF-1 pathways for the treatment of cancer: part I. Arch Immunol Ther Exp (Warsz). 2011;59(4):289-299.
27. Eltzschig HK, Carmeliet P. Hypoxia and inflammation. N Engl J Med. 2011;364(7):656-665.
28. Finger EC, Giaccia AJ. Hypoxia, inflammation, and the tumor microenvironment in metastatic disease. Cancer Metastasis Rev. 2010;29(2): 285-293.
29. Movahedi K, Laoui D, Gysemans C, et al. Different tumor microenvironments contain functionally distinct subsets of macrophages derived from Ly6C(high) monocytes. Cancer Res. 2010;70(14):5728-5739.
30. Caras I, Tucureanu C, Lerescu L, et al. Influence of tumor cell culture supernatants on macrophage functional polarization: in vitro models of macrophage-tumor environment interaction. Tumori. 2011;97(5):647-654.
31. Cools-Lartigue J, Marshall JC, Caissie AL, Saraiva VS, Burnier MN Jr. Secretion of interleukin-6 and prostaglandin E2 during uveal melanoma-monocyte in vitro interactions. Exp Eye Res. 2004;79(4):451-454.
32. Muller-Quernheim UC, Potthast L, Muller-Quernheim J, Zissel G. Tumor-cell co-culture induced alternative activation of macrophages is modulated by interferons in vitro. J Interferon Cytokine Res. 2012;32(4):169-177.