Placotylene A, an inhibitor of the receptor activator of nuclear factor-κB ligand-induced osteoclast differentiation, from a Korean Sponge Placospongia sp.

Marine Drugs

Volumn 12, Issue 4, 2014, Pages 2054-2065

  Kim, Hiyoung ^a   Kim, Kwang Jin ^b   Yeon, Jeong Tae ^b   Kim, Seong Hwan ^c   Won, Dong Hwan ^a   Choi, Hyukjae ^d   Nam, Sang Jip ^e   Son, Young Jin ^b   Kang, Heonjoong ^a  

^a Seoul National University   (South Korea)

^b Sunchon National University   (South Korea)

^c Korea Research Institute of Chemical Technology   (South Korea)

^d Yeungnam University   (South Korea)

^e Ewha Womans University   (South Korea)

Author keywords

Osteoclasts; Placospongia; RANKL; Sponge

Indexed keywords

ANTIMITOTIC AGENT; NATURAL PRODUCT; OSTEOCLAST DIFFERENTIATION FACTOR; PLACOTYLENE A; PLACOTYLENE B; RETROVIRUS VECTOR; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR NFATC1; UNCLASSIFIED DRUG; 14-IODOTETRADECA-13-EN-3,5-DIYN-1-OL; ALKYNE DERIVATIVE; FATTY ALCOHOL;

ANIMAL CELL; ARTICLE; CIS TRANS ISOMERISM; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG ISOLATION; DRUG RESEARCH; DRUG STRUCTURE; GROWTH INHIBITION; IODINATION; ISOMERIZATION; MASS SPECTROMETRY; MOUSE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; OSTEOCLASTOGENESIS; OSTEOPOROSIS; PHYSICAL CHEMISTRY; PLACOSPONGIA; REAL TIME POLYMERASE CHAIN REACTION; SOUTH KOREA; SPONGE (PORIFERA); WESTERN BLOTTING; ANIMAL; CELL DIFFERENTIATION; CHEMISTRY; COMPARATIVE STUDY; DOSE RESPONSE; DRUG EFFECTS; INSTITUTE FOR CANCER RESEARCH MOUSE; ISOLATION AND PURIFICATION; METABOLISM; OSTEOCLAST; STEREOISOMERISM;

ANIMALS; CELL DIFFERENTIATION; DIYNES; DOSE-RESPONSE RELATIONSHIP, DRUG; FATTY ALCOHOLS; MAGNETIC RESONANCE SPECTROSCOPY; MASS SPECTROMETRY; MICE; MICE, INBRED ICR; OSTEOCLASTS; PORIFERA; RANK LIGAND; REPUBLIC OF KOREA; STEREOISOMERISM;

EID: 84900411352     PISSN: None     EISSN: 16603397     Source Type: Journal    
DOI: 10.3390/md12042054     Document Type: Article

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