A paracrine mechanism involving renal tubular cells, adipocytes and macrophages promotes kidney stone formation in a simulated metabolic syndrome environment

Journal of Urology

Volumn 191, Issue 6, 2014, Pages 1906-1912

  Zuo, Li ^a,b   Tozawa, Keiichi ^a   Okada, Atsushi ^a   Yasui, Takahiro ^a   Taguchi, Kazumi ^a   Ito, Yasuhiko ^a   Hirose, Yasuhiko ^a   Fujii, Yasuhiro ^a   Niimi, Kazuhiro ^a   Hamamoto, Shuzo ^a   Ando, Ryosuke ^a   Itoh, Yasunori ^a   Zou, Jiangang ^b   Kohri, Kenjiro ^a  

^a NAGOYA CITY UNIVERSITY GRADUATE SCHOOL OF MEDICAL SCIENCES   (Japan)

^b NANJING MEDICAL UNIVERSITY   (China)

Author keywords

inflammation; kidney; metabolic syndrome X; obesity; urolithiasis

Indexed keywords

MONOCYTE CHEMOTACTIC PROTEIN 1; OSTEOPONTIN; TUMOR NECROSIS FACTOR ALPHA; WHEWELLITE; CALCIUM OXALATE; CYTOKINE;

ADIPOCYTE; ANIMAL CELL; ARTICLE; CELL STRUCTURE; COCULTURE; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; IN VITRO STUDY; INFLAMMATION; KIDNEY TUBULE CELL; MACROPHAGE; METABOLIC SYNDROME X; NEPHROLITHIASIS; NONHUMAN; PARACRINE SIGNALING; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STONE FORMATION; UPREGULATION; 3T3 CELL LINE; ANIMAL; DISEASE MODEL; KIDNEY TUBULE; METABOLISM; MOUSE; PATHOLOGY; EPITHELIUM CELL; POLYMERASE CHAIN REACTION; QUANTITATIVE STUDY;

3T3-L1 CELLS; ADIPOCYTES; ANIMALS; CALCIUM OXALATE; CYTOKINES; DISEASE MODELS, ANIMAL; ENZYME-LINKED IMMUNOSORBENT ASSAY; KIDNEY CALCULI; KIDNEY TUBULES; MACROPHAGES; METABOLIC SYNDROME X; MICE;

EID: 84900405525     PISSN: 00225347     EISSN: 15273792     Source Type: Journal    
DOI: 10.1016/j.juro.2014.01.013     Document Type: Article

References (28)

1. O.W. Moe Kidney stones: pathophysiology and medical management Lancet 367 2006 333
2. G.C. Curhan Epidemiology of stone disease Urol Clin North Am 34 2007 287
3. E.N. Taylor, M.J. Stampfer, and G.C. Curhan Diabetes mellitus and the risk of nephrolithiasis Kidney Int 68 2005 1230
4. E.N. Taylor, M.J. Stampfer, and G.C. Curhan Obesity, weight gain, and the risk of kidney stones JAMA 293 2005 455
5. B.K. Surmi, and A.H. Hasty Macrophage infiltration into adipose tissue: initiation, propagation and remodeling Future Lipidol 3 2008 545
6. Y. Fujii, A. Okada, and T. Yasui et al. Effect of adiponectin on kidney crystal formation in metabolic syndrome model mice via inhibition of inflammation and apoptosis PLoS One 8 2013 e61343
7. R. Cancello, and K. Clement Is obesity an inflammatory illness? Role of low-grade inflammation and macrophage infiltration in human white adipose tissue BJOG 113 2006 1141
8. L.K. Heilbronn, and L.V. Campbell Adipose tissue macrophages, low grade inflammation and insulin resistance in human obesity Curr Pharm Des 14 2008 1225
9. M. Okamoto, Y. Kohjimoto, and A. Iba et al. Calcium oxalate crystal deposition in metabolic syndrome model rat kidneys Int J Urol 17 2010 996
10. K. Kohri, S. Nomura, and Y. Kitamura et al. Structure and expression of the mRNA encoding urinary stone protein (osteopontin) J Biol Chem 268 1993 15180
11. A. Okada, S. Nomura, and Y. Saeki et al. Morphological conversion of calcium oxalate crystals into stones is regulated by osteopontin in mouse kidney J Bone Miner Res 23 2008 1629
12. G. Farell, E. Huang, and S.Y. Kim et al. Modulation of proliferating renal epithelial cell affinity for calcium oxalate monohydrate crystals J Am Soc Nephrol 15 2004 3052
13. J.C. Lieske, R. Leonard, and H. Swift Adhesion of calcium oxalate monohydrate crystals to anionic sites on the surface of renal epithelial cells Am J Physiol 270 1996 F192
14. Y.C. Chien, D.L. Masica, and J.J. Gray et al. Modulation of calcium oxalate dihydrate growth by selective crystal-face binding of phosphorylated osteopontin and polyaspartate peptide showing occlusion by sectoral (compositional) zoning J Biol Chem 284 2009 23491
15. D.J. Samuvel, K.P. Sundararaj, and Y. Li et al. Adipocyte-mononuclear cell interaction, Toll-like receptor 4 activation, and high glucose synergistically up-regulate osteopontin expression via an interleukin 6-mediated mechanism J Biol Chem 285 2010 3916
16. S.R. Khan Role of renal epithelial cells in the initiation of calcium oxalate stones Nephron Exp Nephrol 98 2004 e55
17. T. Umekawa, N. Chegini, and S.R. Khan Increased expression of monocyte chemoattractant protein-1 (MCP-1) by renal epithelial cells in culture on exposure to calcium oxalate, phosphate and uric acid crystals Nephrol Dial Transplant 18 2003 664
18. T. Umekawa, N. Chegini, and S.R. Khan Oxalate ions and calcium oxalate crystals stimulate MCP-1 expression by renal epithelial cells Kidney Int 61 2002 105
19. B.H. Rovin, T. Yoshiumura, and L. Tan Cytokine-induced production of monocyte chemoattractant protein-1 by cultured human mesangial cells J Immunol 148 1992 2148
20. B.H. Rovin, M. Rumancik, and L. Tan et al. Glomerular expression of monocyte chemoattractant protein-1 in experimental and human glomerulonephritis Lab Invest 71 1994 536
21. A. Okada, T. Yasui, and Y. Fujii et al. Renal macrophage migration and crystal phagocytosis via inflammatory-related gene expression during kidney stone formation and elimination in mice: Detection by association analysis of stone-related gene expression and microstructural observation J Bone Miner Res 25 2010 2701
22. M. Halle, A. Berg, and H. Northoff et al. Importance of TNF-alpha and leptin in obesity and insulin resistance: a hypothesis on the impact of physical exercise Exerc Immunol Rev 4 1998 77
23. S.P. Weisberg, D. McCann, and M. Desai et al. Obesity is associated with macrophage accumulation in adipose tissue J Clin Invest 112 2003 1796
24. D.L. Clark, B.A. Connors, and A.P. Evan et al. Localization of renal oxidative stress and inflammatory response after lithotripsy BJU Int 103 2009 1562
25. T. Suganami, J. Nishida, and Y. Ogawa A paracrine loop between adipocytes and macrophages aggravates inflammatory changes: role of free fatty acids and tumor necrosis factor alpha Arterioscler Thromb Vasc Biol 25 2005 2062
26. E. Rhee, L. Santiago, and E. Park et al. Urinary IL-6 is elevated in patients with urolithiasis J Urol 160 1998 2284
27. M.Y. Huang, L.S. Chaturvedi, and S. Koul et al. Oxalate stimulates IL-6 production in HK-2 cells, a line of human renal proximal tubular epithelial cells Kidney Int 68 2005 497
28. T. Hirano Interleukin-6 A.W. Thomson, The Cytokine Handbook 1994 Academic Press San Diego 145 168