메뉴 건너뛰기




Volumn 154, Issue 1, 2014, Pages 229-239

Hugan Qingzhi medication ameliorates hepatic steatosis by activating AMPK and PPARα pathways in L02 cells and HepG2 cells

Author keywords

Adiponectin; AMPK; Hepatic steatosis; Hugan Qingzhi tablet; Oxidative stress; PPAR

Indexed keywords

ACETYL COENZYME A OXIDASE 1; ADIPONECTIN; ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; CARNITINE PALMITOYLTRANSFERASE I; CHINESE DRUG; FATTY ACID; FENOFIBRATE; GLUTATHIONE; HERBACEOUS AGENT; HUGAN QINGZHI; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; LACTATE DEHYDROGENASE; MALONALDEHYDE; OXIDOREDUCTASE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; STEROL REGULATORY ELEMENT BINDING PROTEIN 1; SUPEROXIDE DISMUTASE; TRIACYLGLYCEROL; UNCLASSIFIED DRUG; ADIPOQ PROTEIN, HUMAN; ANTIOXIDANT; OLEIC ACID; PALMITIC ACID;

EID: 84900404551     PISSN: 03788741     EISSN: 18727573     Source Type: Journal    
DOI: 10.1016/j.jep.2014.04.011     Document Type: Article
Times cited : (60)

References (44)
  • 1
    • 21344470150 scopus 로고    scopus 로고
    • Primary study on the application of Serum Pharmacology in Chinese traditional medicine
    • W. Bochu, Z. Liancai, and C. Qi Primary study on the application of Serum Pharmacology in Chinese traditional medicine Colloids and Surfaces B: Biointerfaces 43 2005 194 197
    • (2005) Colloids and Surfaces B: Biointerfaces , vol.43 , pp. 194-197
    • Bochu, W.1    Liancai, Z.2    Qi, C.3
  • 2
    • 0030941803 scopus 로고    scopus 로고
    • The SREBP pathway: Regulation of cholesterol metabolism by proteolysis of a membrane-bound transcription factor
    • M.S. Brown, and J.L. Goldstein The SREBP pathway: regulation of cholesterol metabolism by proteolysis of a membrane-bound transcription factor Cell 89 1997 331 340
    • (1997) Cell , vol.89 , pp. 331-340
    • Brown, M.S.1    Goldstein, J.L.2
  • 4
    • 79954417113 scopus 로고    scopus 로고
    • Lipid-lowering and antioxidant activities of Jiang-Zhi-Ning in Traditional Chinese Medicine
    • J. Chen, H. Zhao, Y. Yang, B. Liu, J. Ni, and W. Wang Lipid-lowering and antioxidant activities of Jiang-Zhi-Ning in Traditional Chinese Medicine Journal of Ethnopharmacology 134 2011 919 930
    • (2011) Journal of Ethnopharmacology , vol.134 , pp. 919-930
    • Chen, J.1    Zhao, H.2    Yang, Y.3    Liu, B.4    Ni, J.5    Wang, W.6
  • 6
    • 79960741184 scopus 로고    scopus 로고
    • Hypolipidemic effects of Alismatis rhizome on lipid profile in mice fed high-fat diet
    • H. Dan, J. Wu, M. Peng, X. Hu, C. Song, Z. Zhou, S. Yu, and N. Fang Hypolipidemic effects of Alismatis rhizome on lipid profile in mice fed high-fat diet Saudi Medical Journal 32 2011 701 707
    • (2011) Saudi Medical Journal , vol.32 , pp. 701-707
    • Dan, H.1    Wu, J.2    Peng, M.3    Hu, X.4    Song, C.5    Zhou, Z.6    Yu, S.7    Fang, N.8
  • 10
    • 73349119128 scopus 로고    scopus 로고
    • Nonalcoholic fatty liver disease in children living in the obeseogenic society
    • A.H. Hesham Nonalcoholic fatty liver disease in children living in the obeseogenic society World Journal of Pediatrics 5 2009 245 254
    • (2009) World Journal of Pediatrics , vol.5 , pp. 245-254
    • Hesham, A.H.1
  • 13
    • 64549117757 scopus 로고    scopus 로고
    • HDMCP uncouples yeast mitochondrial respiration and alleviates steatosis in L02 and hepG2 cells by decreasing ATP and H2O2 levels: A novel mechanism for NAFLD
    • X. Jin, Y.D. Yang, K. Chen, Z.Y. Lv, L. Zheng, Y.P. Liu, S.H. Chen, C.H. Yu, X.Y. Jiang, C.Y. Zhang, and Y.M. Li HDMCP uncouples yeast mitochondrial respiration and alleviates steatosis in L02 and hepG2 cells by decreasing ATP and H2O2 levels: a novel mechanism for NAFLD Journal of Hepatology 50 2009 1019 1028
    • (2009) Journal of Hepatology , vol.50 , pp. 1019-1028
    • Jin, X.1    Yang, Y.D.2    Chen, K.3    Lv, Z.Y.4    Zheng, L.5    Liu, Y.P.6    Chen, S.H.7    Yu, C.H.8    Jiang, X.Y.9    Zhang, C.Y.10    Li, Y.M.11
  • 15
    • 33745834319 scopus 로고    scopus 로고
    • Adiponectin and adiponectin receptors in insulin resistance, diabetes, and the metabolic syndrome
    • T. Kadowaki, T. Yamauchi, N. Kubota, K. Hara, K. Ueki, and K. Tobe Adiponectin and adiponectin receptors in insulin resistance, diabetes, and the metabolic syndrome Journal of Clinical Investigation 116 2006 1784 1792
    • (2006) Journal of Clinical Investigation , vol.116 , pp. 1784-1792
    • Kadowaki, T.1    Yamauchi, T.2    Kubota, N.3    Hara, K.4    Ueki, K.5    Tobe, K.6
  • 16
    • 77957654223 scopus 로고    scopus 로고
    • Nordihydroguaiaretic acid protects against high-fat diet-induced fatty liver by activating AMP-activated protein kinase in obese mice
    • M.S. Lee, D. Kim, K. Jo, and J.K. Hwang Nordihydroguaiaretic acid protects against high-fat diet-induced fatty liver by activating AMP-activated protein kinase in obese mice Biochemical and Biophysical Research Communications 401 2010 92 97
    • (2010) Biochemical and Biophysical Research Communications , vol.401 , pp. 92-97
    • Lee, M.S.1    Kim, D.2    Jo, K.3    Hwang, J.K.4
  • 18
    • 33745815985 scopus 로고    scopus 로고
    • AMP-activated protein kinase signaling in metabolic regulation
    • Y.C. Long, and J.R. Zierath AMP-activated protein kinase signaling in metabolic regulation Journal of Clinical Investigation 116 2006 1776 1783
    • (2006) Journal of Clinical Investigation , vol.116 , pp. 1776-1783
    • Long, Y.C.1    Zierath, J.R.2
  • 19
    • 84863286738 scopus 로고    scopus 로고
    • Xiaoyaosan decoction, a traditional chinese medicine, inhibits oxidative-stress-induced hippocampus neuron apoptosis in vitro
    • Z.Z. Meng, J.H. Hu, J.X. Chen, and G.X. Yue Xiaoyaosan decoction, a traditional chinese medicine, inhibits oxidative-stress-induced hippocampus neuron apoptosis in vitro Evidence-Based Complementary and Alternative Medicine 2012 2012 489254
    • (2012) Evidence-Based Complementary and Alternative Medicine , vol.2012 , pp. 489254
    • Meng, Z.Z.1    Hu, J.H.2    Chen, J.X.3    Yue, G.X.4
  • 20
    • 80051800721 scopus 로고    scopus 로고
    • Decrease of blood lipids induced by Shan-Zha (fruit of Crataegus pinnatifida) is mainly related to an increase of PPARalpha in liver of mice fed high-fat diet
    • C. Niu, C. Chen, L. Chen, K. Cheng, C. Yeh, and J. Cheng Decrease of blood lipids induced by Shan-Zha (fruit of Crataegus pinnatifida) is mainly related to an increase of PPARalpha in liver of mice fed high-fat diet Hormone and Metabolic Research 43 2011 625 630
    • (2011) Hormone and Metabolic Research , vol.43 , pp. 625-630
    • Niu, C.1    Chen, C.2    Chen, L.3    Cheng, K.4    Yeh, C.5    Cheng, J.6
  • 21
    • 84863550183 scopus 로고    scopus 로고
    • Quercetin ameliorates cardiovascular, hepatic, and metabolic changes in diet-induced metabolic syndrome in rats
    • S.K. Panchal, H. Poudyal, and L. Brown Quercetin ameliorates cardiovascular, hepatic, and metabolic changes in diet-induced metabolic syndrome in rats Journal of Nutrition 142 2012 1026 1032
    • (2012) Journal of Nutrition , vol.142 , pp. 1026-1032
    • Panchal, S.K.1    Poudyal, H.2    Brown, L.3
  • 28
    • 67349205050 scopus 로고    scopus 로고
    • Protective effects of serum containing Ginkgo biloba extract on glomerulosclerosis in rat mesangial cells
    • D. Tang, Z. Zhang, Y. Gao, Y. Wei, and L. Han Protective effects of serum containing Ginkgo biloba extract on glomerulosclerosis in rat mesangial cells Journal of Ethnopharmacology 124 2009 26 33
    • (2009) Journal of Ethnopharmacology , vol.124 , pp. 26-33
    • Tang, D.1    Zhang, Z.2    Gao, Y.3    Wei, Y.4    Han, L.5
  • 29
    • 84900418130 scopus 로고    scopus 로고
    • Pharmacodynamics research of Huganqingzhi tablet on rats with non-alcoholic fatty liver model
    • W.J. Tang, B.J. Zhou, and H. Zhou Pharmacodynamics research of Huganqingzhi tablet on rats with non-alcoholic fatty liver model Pharmacology and Clinics of Chinese Materia Medica 29 2013 169 172
    • (2013) Pharmacology and Clinics of Chinese Materia Medica , vol.29 , pp. 169-172
    • Tang, W.J.1    Zhou, B.J.2    Zhou, H.3
  • 32
    • 84873696060 scopus 로고    scopus 로고
    • Quercetin ameliorate insulin resistance and up-regulates cellular antioxidants during oleic acid induced hepatic steatosis in HepG2 cells
    • S. Vidyashankar, V.R. Sandeep, and P.S. Patki Quercetin ameliorate insulin resistance and up-regulates cellular antioxidants during oleic acid induced hepatic steatosis in HepG2 cells Toxicology in vitro 27 2013 945 953
    • (2013) Toxicology in Vitro , vol.27 , pp. 945-953
    • Vidyashankar, S.1    Sandeep, V.R.2    Patki, P.S.3
  • 33
    • 63849206613 scopus 로고    scopus 로고
    • AMP-activated protein kinase in the regulation of hepatic energy metabolism: From physiology to therapeutic perspectives
    • B. Viollet, B. Guigas, J. Leclerc, S. Hebrard, L. Lantier, R. Mounier, F. Andreelli, and M. Foretz AMP-activated protein kinase in the regulation of hepatic energy metabolism: from physiology to therapeutic perspectives Acta Physiologica 196 2009 81 98
    • (2009) Acta Physiologica , vol.196 , pp. 81-98
    • Viollet, B.1    Guigas, B.2    Leclerc, J.3    Hebrard, S.4    Lantier, L.5    Mounier, R.6    Andreelli, F.7    Foretz, M.8
  • 34
    • 83555166208 scopus 로고    scopus 로고
    • Lipid regulation effects of Polygoni Multiflori Radix, its processed products and its major substances on steatosis human liver cell line L02
    • M. Wang, R. Zhao, W. Wang, X. Mao, and J. Yu Lipid regulation effects of Polygoni Multiflori Radix, its processed products and its major substances on steatosis human liver cell line L02 Journal of Ethnopharmacology 139 2012 287 293
    • (2012) Journal of Ethnopharmacology , vol.139 , pp. 287-293
    • Wang, M.1    Zhao, R.2    Wang, W.3    Mao, X.4    Yu, J.5
  • 35
    • 84862801973 scopus 로고    scopus 로고
    • Emerging approaches of traditional Chinese medicine formulas for the treatment of hyperlipidemia
    • W. Xie, Y. Zhao, and L. Du Emerging approaches of traditional Chinese medicine formulas for the treatment of hyperlipidemia Journal of Ethnopharmacology 140 2012 345 367
    • (2012) Journal of Ethnopharmacology , vol.140 , pp. 345-367
    • Xie, W.1    Zhao, Y.2    Du, L.3
  • 36
    • 0041302377 scopus 로고    scopus 로고
    • The fat-derived hormone adiponectin alleviates alcoholic and nonalcoholic fatty liver diseases in mice
    • A. Xu, Y. Wang, H. Keshaw, L.Y. Xu, K.S. Lam, and G.J. Cooper The fat-derived hormone adiponectin alleviates alcoholic and nonalcoholic fatty liver diseases in mice Journal of Clinical Investigation 112 2003 91 100
    • (2003) Journal of Clinical Investigation , vol.112 , pp. 91-100
    • Xu, A.1    Wang, Y.2    Keshaw, H.3    Xu, L.Y.4    Lam, K.S.5    Cooper, G.J.6
  • 37
    • 67349248083 scopus 로고    scopus 로고
    • Pomegranate flower ameliorates fatty liver in an animal model of type 2 diabetes and obesity
    • K.Z. Xu, C. Zhu, M.S. Kim, J. Yamahara, and Y. Li Pomegranate flower ameliorates fatty liver in an animal model of type 2 diabetes and obesity Journal of Ethnopharmacology 123 2009 280 287
    • (2009) Journal of Ethnopharmacology , vol.123 , pp. 280-287
    • Xu, K.Z.1    Zhu, C.2    Kim, M.S.3    Yamahara, J.4    Li, Y.5
  • 39
    • 84878723669 scopus 로고    scopus 로고
    • Serum containing Tao-Hong-Si-Wu decoction induces human endothelial cell VEGF production via PI3K/Akt-eNOS signaling
    • D. Yin, Z. Liu, D. Peng, Y. Yang, X. Gao, F. Xu, and L. Han Serum containing Tao-Hong-Si-Wu decoction induces human endothelial cell VEGF production via PI3K/Akt-eNOS signaling Evidence-Based Complementary and Alternative Medicine 2013 2013 195158
    • (2013) Evidence-Based Complementary and Alternative Medicine , vol.2013 , pp. 195158
    • Yin, D.1    Liu, Z.2    Peng, D.3    Yang, Y.4    Gao, X.5    Xu, F.6    Han, L.7
  • 40
    • 9644290860 scopus 로고    scopus 로고
    • The role of AMP-activated protein kinase in the action of ethanol in the liver
    • M. You, M. Matsumoto, C.M. Pacold, W.K. Cho, and D.W. Crabb The role of AMP-activated protein kinase in the action of ethanol in the liver Gastroenterology 127 2004 1798 1808
    • (2004) Gastroenterology , vol.127 , pp. 1798-1808
    • You, M.1    Matsumoto, M.2    Pacold, C.M.3    Cho, W.K.4    Crabb, D.W.5
  • 41
    • 34248578966 scopus 로고    scopus 로고
    • In vitro inhibition of proliferation of vascular smooth muscle cells by serum of rats treated with Dahuang Zhechong pill
    • Y.H. Zhang, J.T. Liu, B.Y. Wen, and X.H. Xiao in vitro inhibition of proliferation of vascular smooth muscle cells by serum of rats treated with Dahuang Zhechong pill Journal of Ethnopharmacology 112 2007 375 379
    • (2007) Journal of Ethnopharmacology , vol.112 , pp. 375-379
    • Zhang, Y.H.1    Liu, J.T.2    Wen, B.Y.3    Xiao, X.H.4
  • 42
    • 79955939296 scopus 로고    scopus 로고
    • A novel agonist of PPAR-gamma based on barbituric acid alleviates the development of non-alcoholic fatty liver disease by regulating adipocytokine expression and preventing insulin resistance
    • H. Zheng, S. Li, L. Ma, L. Cheng, C. Deng, Z. Chen, C. Xie, M. Xiang, W. Jiang, and L. Chen A novel agonist of PPAR-gamma based on barbituric acid alleviates the development of non-alcoholic fatty liver disease by regulating adipocytokine expression and preventing insulin resistance European Journal of Pharmacology 659 2011 244 251
    • (2011) European Journal of Pharmacology , vol.659 , pp. 244-251
    • Zheng, H.1    Li, S.2    Ma, L.3    Cheng, L.4    Deng, C.5    Chen, Z.6    Xie, C.7    Xiang, M.8    Jiang, W.9    Chen, L.10


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.