HDMCP uncouples yeast mitochondrial respiration and alleviates steatosis in L02 and hepG2 cells by decreasing ATP and H2O2 levels: A novel mechanism for NAFLD

Journal of Hepatology

Volumn 50, Issue 5, 2009, Pages 1019-1028

  Jin, Xi ^a   Yang, Yi da ^a   Chen, Kun ^b   Lv, Zhi yuan ^b   Zheng, Lin ^a   Liu, Ya ping ^b   Chen, Shao hua ^a   Yu, Chao hui ^a   Jiang, Xue yuan ^b   Zhang, Cheng yu ^b   Li, You ming ^a  

^a ZHEJIANG UNIVERSITY SCHOOL OF MEDICINE   (China)

^b NANJING UNIVERSITY   (China)

Author keywords

HDMCP; hepG2 cells; L02 cells; Non alcoholic fatty liver disease; Steatosis; Uncoupling protein

Indexed keywords

ADENOSINE TRIPHOSPHATE; GUANOSINE DIPHOSPHATE; HEPATOCELLUAR DOWNREGULATED MITOCHONDRIAL CARRIER PROTEIN; HYDROGEN PEROXIDE; PROTON TRANSPORTING ADENOSINE TRIPHOSPHATE SYNTHASE; UNCLASSIFIED DRUG; UNCOUPLING PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL CULTURE; CELL STRAIN HEPG2; CONTROLLED STUDY; CYTOPATHOLOGY; HUMAN; HUMAN CELL; HUMAN TISSUE; MITOCHONDRIAL RESPIRATION; MOLECULAR CLONING; MOUSE; NONALCOHOLIC FATTY LIVER; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN DEPLETION; PROTEIN EXPRESSION; PROTEIN FUNCTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA INTERFERENCE; STAINING; WESTERN BLOTTING; YEAST;

ADENOSINE TRIPHOSPHATE; AMINO ACID SEQUENCE; ANIMALS; CARCINOMA, HEPATOCELLULAR; CELL LINE; CELL LINE, TUMOR; DISEASE MODELS, ANIMAL; FATTY LIVER; HEPATOCYTES; HUMANS; HYDROGEN PEROXIDE; ION CHANNELS; LIVER NEOPLASMS; MEMBRANE TRANSPORT PROTEINS; MITOCHONDRIAL PROTEINS; MOLECULAR SEQUENCE DATA; RATS; RATS, SPRAGUE-DAWLEY;

EID: 64549117757     PISSN: 01688278     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jhep.2008.10.034     Document Type: Article

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