메뉴 건너뛰기




Volumn 29, Issue 24, 2013, Pages 3211-3219

GPCR ontology: Development and application of a G protein-coupled receptor pharmacology knowledge framework

Author keywords

[No Author keywords available]

Indexed keywords

DRUG; G PROTEIN COUPLED RECEPTOR; LIGAND;

EID: 84900364388     PISSN: 13674803     EISSN: 14602059     Source Type: Journal    
DOI: 10.1093/bioinformatics/btt565     Document Type: Article
Times cited : (31)

References (37)
  • 1
    • 84870649451 scopus 로고    scopus 로고
    • BAOSearch: A semantic web application for biological screening and drug discovery research
    • Shanghai, China (15 October 2013, date last accessed)
    • Abeyruwan, S. et al. (2010) BAOSearch: a semantic web application for biological screening and drug discovery research. In: Semantic Web Challenge, 9th International Semantic Web Conference (ISWC). Shanghai, China; http://challenge.semanticweb.org/submissions/swc2010-submission-20.pdf (15 October 2013, date last accessed).
    • (2010) Semantic Web Challenge, 9th International Semantic Web Conference (ISWC)
    • Abeyruwan, S.1
  • 2
    • 67449132007 scopus 로고    scopus 로고
    • Biological knowledge management: The emerging role of the semantic web technologies
    • Antezana, E. et al. (2009) Biological knowledge management: the emerging role of the Semantic Web technologies. Brief. Bioinformatics, 10, 392-407.
    • (2009) Brief. Bioinformatics , vol.10 , pp. 392-407
    • Antezana, E.1
  • 3
    • 77955780354 scopus 로고    scopus 로고
    • Web ontology language: OWL
    • Staab, S. and Studer, R. (eds) Springer-Verlag, Berlin Heidelberg
    • Antoniou, G. and Harmelen, F.V. (2009) Web Ontology Language: OWL. In: Staab, S. and Studer, R. (eds) Handbook on Ontologies. Springer-Verlag, Berlin Heidelberg, pp. 91-110.
    • (2009) Handbook on Ontologies , pp. 91-110
    • Antoniou, G.1    Harmelen, F.V.2
  • 4
    • 0034069495 scopus 로고    scopus 로고
    • Gene ontology: Tool for the unification of biology
    • Ashburner, M. et al. (2000) Gene ontology: tool for the unification of biology. The Gene Ontology Consortium. Nat. Genet., 25, 25-29.
    • (2000) The Gene Ontology Consortium. Nat. Genet. , vol.25 , pp. 25-29
    • Ashburner, M.1
  • 5
    • 8444225024 scopus 로고    scopus 로고
    • NIH molecular libraries initiative
    • Austin, C.P. et al. (2004) NIH molecular libraries initiative. Science, 306, 1138-1139.
    • (2004) Science , vol.306 , pp. 1138-1139
    • Austin, C.P.1
  • 6
    • 48249158190 scopus 로고    scopus 로고
    • Bio2RDF: Towards a mashup to build bioinformatics knowledge systems
    • Belleau, F. et al. (2008) Bio2RDF: towards a mashup to build bioinformatics knowledge systems. J. Biomed Inform., 41, 706-716.
    • (2008) J. Biomed Inform. , vol.41 , pp. 706-716
    • Belleau, F.1
  • 8
    • 38549127678 scopus 로고    scopus 로고
    • ChEBI: A database and ontology for chemical entities of biological interest
    • Degtyarenko, K. et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res., 36, D344-D350.
    • (2008) Nucleic Acids Res. , vol.36 , pp. D344-D350
    • Degtyarenko, K.1
  • 9
    • 77954218503 scopus 로고    scopus 로고
    • Therapeutic anti-inflammatory potential of formyl-peptide receptor agonists
    • Dufton, N. and Perretti, M. (2010) Therapeutic anti-inflammatory potential of formyl-peptide receptor agonists. Pharmacol. Ther., 127, 175-188.
    • (2010) Pharmacol. Ther. , vol.127 , pp. 175-188
    • Dufton, N.1    Perretti, M.2
  • 11
    • 80052686988 scopus 로고    scopus 로고
    • Refining efficacy: Exploiting functional selectivity for drug discovery
    • Gesty-Palmer, D. and Luttrell, L.M. (2011) Refining efficacy: exploiting functional selectivity for drug discovery. Adv. Pharmacol., 62, 79-107.
    • (2011) Adv. Pharmacol. , vol.62 , pp. 79-107
    • Gesty-Palmer, D.1    Luttrell, L.M.2
  • 12
    • 84861075468 scopus 로고    scopus 로고
    • Structure of the δ5-opioid receptor bound to naltrindole
    • Granier, S. et al. (2012) Structure of the δ5-opioid receptor bound to naltrindole. Nature, 485, 400-404.
    • (2012) Nature , vol.485 , pp. 400-404
    • Granier, S.1
  • 13
    • 0037252680 scopus 로고    scopus 로고
    • GPCRDB information system for G protein-coupled receptors
    • Horn, F. et al. (2003) GPCRDB information system for G protein-coupled receptors. Nucleic Acids Res., 31, 294-297.
    • (2003) Nucleic Acids Res. , vol.31 , pp. 294-297
    • Horn, F.1
  • 14
    • 77953235731 scopus 로고    scopus 로고
    • A novel chemogenomics analysis of G protein coupled receptors (GPCRs) and their ligands: A potential strategy for receptor de-orphanization
    • Van der Horst, E. et al. (2010) A novel chemogenomics analysis of G protein coupled receptors (GPCRs) and their ligands: a potential strategy for receptor de-orphanization. BMC Bioinformatics, 11, 316.
    • (2010) BMC Bioinformatics , vol.11 , pp. 316
    • Van Der Horst, E.1
  • 15
    • 79952784761 scopus 로고    scopus 로고
    • Recognition in the face of diversity: Interactions of heterotrimeric G proteins and G protein-coupled receptor (GPCR) kinases with activated GPCRs
    • Huang, C.C. and Tesmer, J.G. (2011) Recognition in the face of diversity: interactions of heterotrimeric G proteins and G protein-coupled receptor (GPCR) kinases with activated GPCRs. J. Biol. Chem., 286, 7715-7721.
    • (2011) J. Biol. Chem. , vol.286 , pp. 7715-7721
    • Huang, C.C.1    Tesmer, J.G.2
  • 16
    • 70349473057 scopus 로고    scopus 로고
    • Regulator of G-protein signaling (RGS) proteins in cancer biology
    • Hurst, J.H. and Hooks, S.B. (2009) Regulator of G-protein signaling (RGS) proteins in cancer biology. Biochem. Pharmacol., 78, 1289-1297.
    • (2009) Biochem. Pharmacol. , vol.78 , pp. 1289-1297
    • Hurst, J.H.1    Hooks, S.B.2
  • 17
    • 77954528981 scopus 로고    scopus 로고
    • GPCR-OKB: The G protein coupled receptor oligomer knowledge base
    • Khelashvili, G et al. (2010) GPCR-OKB: the G protein coupled receptor oligomer knowledge base. Bioinformatics, 26, 1804-1805.
    • (2010) Bioinformatics , vol.26 , pp. 1804-1805
    • Khelashvili, G.1
  • 18
    • 42149181885 scopus 로고    scopus 로고
    • Structural diversity of G protein-coupled receptors and significance for drug discovery
    • Lagerstrom, M.C. and Schioth, H.B. (2008) Structural diversity of G protein-coupled receptors and significance for drug discovery. Nature. Rev. Drug Discov., 7, 339-357.
    • (2008) Nature. Rev. Drug Discov. , vol.7 , pp. 339-357
    • Lagerstrom, M.C.1    Schioth, H.B.2
  • 19
    • 84861096654 scopus 로고    scopus 로고
    • Crystal structure of the μ-opioid receptor bound to a morphinan antagonist
    • Manglik, A. et al. (2012) Crystal structure of the μ-opioid receptor bound to a morphinan antagonist. Nature, 485, 321-326.
    • (2012) Nature , vol.485 , pp. 321-326
    • Manglik, A.1
  • 20
    • 84870244777 scopus 로고    scopus 로고
    • Ontologies versus relational databases: Are they so different? A comparison
    • Martinez-Cruz, C. et al. (2012) Ontologies versus relational databases: are they so different? A comparison. Artif Intell. Rev., 38, 271-290.
    • (2012) Artif Intell. Rev. , vol.38 , pp. 271-290
    • Martinez-Cruz, C.1
  • 21
    • 78651286167 scopus 로고    scopus 로고
    • The protein ontology: A structured representation of protein forms and complexes
    • Natale, D.A. et al. (2011) The Protein Ontology: a structured representation of protein forms and complexes. Nucleic Acids Res., 39, D539-D545.
    • (2011) Nucleic Acids Res. , vol.39 , pp. D539-D545
    • Natale, D.A.1
  • 22
    • 33644875256 scopus 로고    scopus 로고
    • GLIDA: GPCR-ligand database for chemical genomic drug discovery
    • Okuno, Y. et al. (2006) GLIDA: GPCR-ligand database for chemical genomic drug discovery. Nucleic Acids Res., 34, D673-D677.
    • (2006) Nucleic Acids Res. , vol.34 , pp. D673-D677
    • Okuno, Y.1
  • 23
    • 41149160103 scopus 로고    scopus 로고
    • Biological data integration using semantic web technologies
    • Pasquier, C. (2008) Biological data integration using Semantic Web technologies. Biochimie, 90, 584-594.
    • (2008) Biochimie , vol.90 , pp. 584-594
    • Pasquier, C.1
  • 24
    • 33748040760 scopus 로고    scopus 로고
    • National center for biomedical ontology: Advancing biomedicine through structured organization of scientific knowledge
    • Rubin et al. (2006) National Center for Biomedical Ontology: advancing biomedicine through structured organization of scientific knowledge. Omics, 10, 185-198.
    • (2006) Omics , vol.10 , pp. 185-198
    • Rubin1
  • 25
    • 79955406950 scopus 로고    scopus 로고
    • BioAssay ontology annotations facilitate cross-analysis of diverse high-throughput screening data sets
    • Schurer et al. (2011) BioAssay ontology annotations facilitate cross-analysis of diverse high-throughput screening data sets. J. Biomol. Screening, 16, 415-426.
    • (2011) J. Biomol. Screening , vol.16 , pp. 415-426
    • Schurer1
  • 26
    • 78651303897 scopus 로고    scopus 로고
    • IUPHAR-DB: New receptors and tools for easy searching and visualization of pharmacological data
    • Sharman, J.L. et al. (2011) IUPHAR-DB: new receptors and tools for easy searching and visualization of pharmacological data. Nucleic Acids Res., 39, D534-D538.
    • (2011) Nucleic Acids Res. , vol.39 , pp. D534-D538
    • Sharman, J.L.1
  • 27
    • 22044433259 scopus 로고    scopus 로고
    • Relations in biomedical ontologies
    • Smith, B. et al. (2005) Relations in biomedical ontologies. Genome Biol., 6, R46.
    • (2005) Genome Biol. , vol.6 , pp. R46
    • Smith, B.1
  • 28
    • 35948989284 scopus 로고    scopus 로고
    • The OBO foundry: Coordinated evolution of ontologies to support biomedical data integration
    • Smith, B. et al. (2007) The OBO Foundry: coordinated evolution of ontologies to support biomedical data integration. Nat. Biotechnol., 25, 1251-1255.
    • (2007) Nat. Biotechnol. , vol.25 , pp. 1251-1255
    • Smith, B.1
  • 29
    • 84861019261 scopus 로고    scopus 로고
    • Structure of the nociceptin/orphanin FQ receptor in complex with a peptide mimetic
    • Thompson, A.A. et al. (2012) Structure of the nociceptin/orphanin FQ receptor in complex with a peptide mimetic. Nature, 485, 395-399.
    • (2012) Nature , vol.485 , pp. 395-399
    • Thompson, A.A.1
  • 30
    • 70450171097 scopus 로고    scopus 로고
    • Signaling through G protein coupled receptors
    • Tuteja, N. (2009) Signaling through G protein coupled receptors. Plant Signal. Behav., 4, 942-947.
    • (2009) Plant Signal. Behav. , vol.4 , pp. 942-947
    • Tuteja, N.1
  • 31
    • 84869127262 scopus 로고    scopus 로고
    • Formalization, annotation and analysis of diverse drug and probe screening assay datasets using the BioAssay ontology (BAO)
    • Vempati, U.D. et al. (2012) Formalization, annotation and analysis of diverse drug and probe screening assay datasets using the BioAssay Ontology (BAO). PLoS One, 7, e49198.
    • (2012) PLoS One , vol.7
    • Vempati, U.D.1
  • 32
    • 79959471969 scopus 로고    scopus 로고
    • BioAssay ontology (BAO): A semantic description of bioassays and high-throughput screening results
    • Visser, U. et al. (2011) BioAssay Ontology (BAO): a semantic description of bioassays and high-throughput screening results. BMC Bioinformatics, 12, 257.
    • (2011) BMC Bioinformatics , vol.12 , pp. 257
    • Visser, U.1
  • 33
    • 67849104638 scopus 로고    scopus 로고
    • PubChem: A public information system for analyzing bioactivities of small molecules
    • Wang, Y. et al. (2009) PubChem: a public information system for analyzing bioactivities of small molecules. Nucleic Acids Res, 37, W623-W633.
    • (2009) Nucleic Acids Res , vol.37 , pp. W623-W633
    • Wang, Y.1
  • 34
    • 84860674656 scopus 로고    scopus 로고
    • Systems chemical biology and the semantic web: What they mean for the future of drug discovery research
    • Wild, D. et al. (2012) Systems chemical biology and the Semantic Web: what they mean for the future of drug discovery research. Drug Discov. Today, 17, 469-474.
    • (2012) Drug Discov. Today , vol.17 , pp. 469-474
    • Wild, D.1
  • 35
    • 70449578266 scopus 로고    scopus 로고
    • The crystal structure of sphingosine-1-phosphate in complex with a fab fragment reveals metal bridging of an antibody and its antigen
    • Wojciak, J.M. et al. (2009) The crystal structure of sphingosine-1-phosphate in complex with a Fab fragment reveals metal bridging of an antibody and its antigen. Proc. Natl Acad. Sci. USA, 106, 17717-17722.
    • (2009) Proc. Natl Acad. Sci. USA , vol.106 , pp. 17717-17722
    • Wojciak, J.M.1
  • 36
    • 84862777742 scopus 로고    scopus 로고
    • Structure of the human k-opioid receptor in complex with JDTic
    • Wu et al. (2012) Structure of the human k-opioid receptor in complex with JDTic. Nature, 485, 327-332.
    • (2012) Nature , vol.485 , pp. 327-332
    • Wu1
  • 37
    • 0035013840 scopus 로고    scopus 로고
    • Regulator of G protein signaling proteins: Novel multifunctional drug targets
    • Zhong, H. and Neubig, R.R. (2001) Regulator of G protein signaling proteins: novel multifunctional drug targets. J. Pharmacol. Exp. Ther., 297, 837-845.
    • (2001) J. Pharmacol. Exp. Ther. , vol.297 , pp. 837-845
    • Zhong, H.1    Neubig, R.R.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.