Ethanol extract of Astragali Radix and Salviae Miltiorrhizae Radix, Myelophil, exerts anti-amnesic effect in a mouse model of scopolamine-induced memory deficits

Journal of Ethnopharmacology

Volumn 153, Issue 3, 2014, Pages 782-792

  Lee, Jin Seok ^a   Kim, Hyeong Geug ^a   Han, Jong Min ^a   Kim, Dong Woon ^b   Yi, Min Hee ^b   Son, Seung Wan ^c   Kim, Young Ae ^a   Lee, Jong Suk ^d   Choi, Min Kyeong ^a   Son, Chang Gue ^a  

^a Daejeon University   (South Korea)

^b Chungnam National University   (South Korea)

^c Korea University   (South Korea)

^d Gyeonggi Institute of Science and Technology Promotion   (South Korea)

Author keywords

Acetylcholinesterase; Antioxidant; Extracellular signal regulated kinase; Memory; Oxidative stress; Scopolamine

Indexed keywords

ACETYLCHOLINESTERASE; ASTRAGALUS EXTRACT; CATALASE; CHINESE DRUG; CHOLINESTERASE INHIBITOR; GLUTATHIONE; GLUTATHIONE TRANSFERASE; HERBACEOUS AGENT; MALONALDEHYDE; MITOGEN ACTIVATED PROTEIN KINASE; MUSCARINIC M1 RECEPTOR; MYELOPHIL; NEUROPROTECTIVE AGENT; NOOTROPIC AGENT; REACTIVE OXYGEN METABOLITE; SALVIA MILTIORRHIZA EXTRACT; SCOPOLAMINE; TACRINE; UNCLASSIFIED DRUG; ALCOHOL; MUSCARINIC RECEPTOR; NITRIC OXIDE; SCOPOLAMINE BROMIDE; SOLVENT; SUPEROXIDE DISMUTASE;

ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTICHOLINERGIC EFFECT; ANTIOXIDANT ACTIVITY; ARTICLE; ASTRAGALUS MEMBRANACEUS; BRAIN DYSFUNCTION; BRAIN LEVEL; BRAIN TISSUE; CHINESE MEDICINE; CONTROLLED STUDY; DISEASE MODEL; DRUG EFFECT; ENZYME ACTIVITY; GENE EXPRESSION; INFANT; LATENT PERIOD; MALE; MORRIS WATER MAZE TEST; MOUSE; MOUSE MODEL; NEUROPROTECTION; NONHUMAN; NUCLEOTIDE SEQUENCE; OXIDATIVE STRESS; PLANT ROOT; PROTEIN EXPRESSION; RESPONSE TIME; SALVIA; SALVIA MILTIORRHIZA; SCOPOLAMINE-INDUCED AMNESIA; SPATIAL MEMORY; ANIMAL; ASTRAGALUS (PLANT); BRAIN; C57BL MOUSE; CELL CULTURE; CHEMICALLY INDUCED; CHEMISTRY; DRUG EFFECTS; GENETICS; MAZE TEST; MEMORY DISORDERS; METABOLISM; MICROGLIA; PHYTOTHERAPY; SIGNAL TRANSDUCTION; SPRAGUE DAWLEY RAT;

ANIMALIA; MUS;

ACETYLCHOLINESTERASE; ANIMALS; ASTRAGALUS PLANT; BRAIN; CATALASE; CELLS, CULTURED; DISEASE MODELS, ANIMAL; DRUGS, CHINESE HERBAL; ETHANOL; GLUTATHIONE; GLUTATHIONE TRANSFERASE; MALE; MALONDIALDEHYDE; MAP KINASE SIGNALING SYSTEM; MAZE LEARNING; MEMORY DISORDERS; MICE, INBRED C57BL; MICROGLIA; NEUROPROTECTIVE AGENTS; NITRIC OXIDE; PHYTOTHERAPY; PLANT ROOTS; RATS, SPRAGUE-DAWLEY; REACTIVE OXYGEN SPECIES; RECEPTORS, MUSCARINIC; SALVIA MILTIORRHIZA; SCOPOLAMINE HYDROBROMIDE; SOLVENTS; SUPEROXIDE DISMUTASE;

EID: 84900343157     PISSN: 03788741     EISSN: 18727573     Source Type: Journal    
DOI: 10.1016/j.jep.2014.03.048     Document Type: Article

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