Virus and cystic fibrosis: Rhinoviruses are associated with exacerbations in adult patients

Journal of Clinical Virology

Volumn 60, Issue 2, 2014, Pages 147-153

  Goffard, Anne ^a   Lambert, Valérie ^a   Salleron, Julia ^a   Herwegh, Stéphanie ^a   Engelmann, Ilka ^a,b   Pinel, Claudine ^c   Pin, Isabelle ^c   Perrez, Thierry ^d   Prévotat, Anne ^d   Dewilde, Anny ^a   Delhaes, Laurence ^a,e,f  

^a UNIV LILLE   (France)

^b University Lille   (France)

^c GRENOBLE UNIVERSITY HOSPITAL   (France)

^d LILLE UNIVERSITY HOSPITAL   (France)

^e INSTITUT PASTEUR DE LILLE   (France)

^f INSERM U1019   (France)

Author keywords

Cystic fibrosis; PCR; Pulmonary exacerbation; Rhinovirus

Indexed keywords

NUCLEIC ACID; VIRUS RNA;

5' UNTRANSLATED REGION; ADULT; ARTICLE; CLINICAL ARTICLE; CORONAVIRUS; CYSTIC FIBROSIS; DISEASE EXACERBATION; EXTRACTION; FEMALE; GENETIC VARIABILITY; HUMAN; LUNG; MALE; MICROFLORA; NONHUMAN; PHYLOGENY; PRIORITY JOURNAL; RESPIRATORY VIRUS; RHINOVIRUS; SPUTUM ANALYSIS; VIRUS DETECTION; VIRUS GENOME; VIRUS RECOMBINATION; COMPLICATION; DNA SEQUENCE; GENETICS; ISOLATION AND PURIFICATION; LUNG DISEASE; MOLECULAR GENETICS; PICORNAVIRIDAE INFECTIONS; PREVALENCE; RESPIRATORY TRACT INFECTIONS; SPUTUM; VIROLOGY;

ADULT; CYSTIC FIBROSIS; FEMALE; HUMANS; LUNG DISEASES; MALE; MOLECULAR SEQUENCE DATA; PICORNAVIRIDAE INFECTIONS; PREVALENCE; RESPIRATORY TRACT INFECTIONS; RHINOVIRUS; RNA, VIRAL; SEQUENCE ANALYSIS, DNA; SPUTUM;

EID: 84900310195     PISSN: 13866532     EISSN: 18735967     Source Type: Journal    
DOI: 10.1016/j.jcv.2014.02.005     Document Type: Article

References (39)

1. Sibley C.D., Parkins M.D., Rabin H.R., Duan K., Norgaard J.C., Surette M.G. A polymicrobial perspective of pulmonary infections exposes an enigmatic pathogen in cystic fibrosis patients. Proc Natl Acad Sci U S A 2008, 105:15070-15075.
2. Delhaes L., Monchy S., Fréalle E., Hubans C., Salleron J., Leroy S., et al. The airway microbiota in cystic fibrosis: a complex fungal and bacterial community - implications for therapeutic management. PLoS One 2012, 7:e36313.
3. Gangell C., Gard S., Douglas T., Park J., de Klerk N., Keil T., et al. Inflammatory responses to individual microorganisms in the lungs of children with cystic fibrosis. Clin Infect Dis 2011, 53:425-432.
4. Singanayagam A., Joshi P.V., Mallia P., Johnston S.L. Viruses exacerbating chronic pulmonary disease: the role of immune modulation. BMC Med 2012, 10:27.
5. Contoli M., Marku B., Conti V., Saturni S., Caramori G., Papi A. Viral infections in exacerbations of asthma and chronic obstructive pulmonary disease. Minerva Med 2009, 100:467-478.
6. Wat D., Gelder C., Hibbitts S., Cafferty F., Bowler I., Pierrepoint M., et al. The role of respiratory viruses in cystic fibrosis. J Cyst Fibros 2008, 7:320-328.
7. De Almeida M.B., Zerbinati R.M., Tateno A.F., Oliveira C.M., Romão R.M., Rodrigues J.C., et al. Rhinovirus C and respiratory exacerbations in children with cystic fibrosis. Emerg Infect Dis 2010, 16:996-999.
8. Hoek R.A.S., Paats M.S., Pas S.D., Bakker M., Hoogsteden H.C., Boucher C.A.B., et al. Incidence of viral respiratory pathogens causing exacerbations in adult cystic fibrosis patients. Scand J Infect Dis 2013, 45:65-69.
9. Stelzer-Braid S., Johal H., Skilbeck K., Steller A., Alsubie H., Tovey E., et al. Detection of viral and bacterial respiratory pathogens in patients with cystic fibrosis. J Virol Methods 2012, 186:109-112.
10. Lau S.K.P., Yip C.C.Y., Tsoi H.-W., Lee R.A., So L.-Y., Lau Y-L., et al. Clinical features and complete genome characterization of a distinct human rhinovirus (HRV) genetic cluster, probably representing a previously undetected HRV species, HRV-C, associated with acute respiratory illness in children. J Clin Microbiol 2007, 45:3655-3664.
11. Louie J.K., Yagi S., Nelson F.A., Kiang D., Glaser C.A., Rosenberg J., et al. Rhinovirus outbreak in a long term care facility for elderly persons associated with unusually high mortality. Clin Infect Dis 2005, 41:262-265.
12. Ison M.G., Hayden F.G., Kaiser L., Corey L., Boeckh M. Rhinovirus infections in hematopoietic stem cell transplant recipients with pneumonia. Clin Infect Dis 2003, 36:1139-1143.
13. Bilton D., Canny G., Conway S., Dumcius S., Hjelte L., Proesmans M., et al. Pulmonary exacerbation: towards a definition for use in clinical trials, report from the EuroCareCF Working Group on outcome parameters in clinical trials. J Cyst Fibros 2011, 10(Suppl. 2):S79-S81.
14. Montes-Cano M.A., de la Horra C., Dapena F.J., Mateos I., Friaza V., Respaldiza N., et al. Dynamic colonisation by different Pneumocystis jirovecii genotypes in cystic fibrosis patients. Clin Microbiol Infect 2007, 13:1008-1011.
15. Wisdom A., Leitch E.C.M., Gaunt E., Harvala H., Simmonds P. Screening respiratory samples for detection of human rhinoviruses (HRVs) and enteroviruses: comprehensive VP4-VP2 typing reveals high incidence and genetic diversity of HRV species C. J Clin Microbiol 2009, 47:3958-3967.
16. Tamura K., Peterson D., Peterson N., Stecher G., Nei M., Kumar S. MEGA5: molecular evolutionary genetics analysis using maximum likelihood, evolutionary distance, and maximum parsimony methods. Mol Biol Evol 2011, 28:2731-2739.
17. Blyth C.C., Middleton P.G., Harun A., Sorrell T.C., Meyer W., Chen S.C.-A. Clinical associations and prevalence of Scedosporium spp. in Australian cystic fibrosis patients: identification of novel risk factors?. Med Mycol 2010, 48(Suppl. 1):S37-S44.
18. Stevens D.A., Moss R.B., Kurup V.P., Knutsen A.P., Greenberger P., Judson M.A., et al. Allergic bronchopulmonary aspergillosis in cystic fibrosis - state of the art: Cystic Fibrosis Foundation Consensus Conference. Clin Infect Dis 2003, 37(Suppl. 3):S225-S264.
19. Huang T., Wang W., Bessaud M., Ren P., Sheng J., Yan H., et al. Evidence of recombination and genetic diversity in human rhinoviruses in children with acute respiratory infection. PLoS One 2009, 4:e6355.
20. McIntyre C.L., McWilliam Leitch E.C., Savolainen-Kopra C., Hovi T., Simmonds P. Analysis of genetic diversity and sites of recombination in human rhinovirus species C. J Virol 2010, 84:10297-10310.
21. Wisdom A., Kutkowska A.E., McWilliam Leitch E.C., Gaunt E., Templeton K., Harvala H., et al. Genetics, recombination and clinical features of human rhinovirus species C (HRV-C) infections; interactions of HRV-C with other respiratory viruses. PLoS One 2009, 4:e8518.
22. Lysholm F., Wetterbom A., Lindau C., Darban H., Bjerkner A., Fahlander K., et al. Characterization of the viral microbiome in patients with severe lower respiratory tract infections, using metagenomic sequencing. PLoS One 2012, 7:e30875.
23. Armstrong D., Grimwood K., Carlin J.B., Carzino R., Hull J., Olinsky A., et al. Severe viral respiratory infections in infants with cystic fibrosis. Pediatr Pulmonol 1998, 26:371-379.
24. Olesen H.V., Nielsen L.P., Schiotz P.O. Viral and atypical bacterial infections in the outpatient pediatric cystic fibrosis clinic. Pediatr Pulmonol 2006, 41:1197-1204.
25. Asner S., Waters V., Solomon M., Yau Y., Richardson S.E., Grasemann H., et al. Role of respiratory viruses in pulmonary exacerbations in children with cystic fibrosis. J Cyst Fibros 2012, 11(September (5)):433-439.
26. Burns J.L., Emerson J., Kuypers J., Campbell A.P., Gibson R.L., McNamara S., et al. Respiratory viruses in children with cystic fibrosis: viral detection and clinical findings. Influenza Other Respir Viruses 2012, 6:218-223.
27. Lim Y.W., Schmieder R., Haynes M., Willner D., Furlan M., Youle M., et al. Metagenomics and metatranscriptomics: Windows on CF-associated viral and microbial communities. J Cyst Fibros 2012, 12(March (2)):154-164.
28. Wang E.E., Prober C.G., Manson B., Corey M., Levison H. Association of respiratory viral infections with pulmonary deterioration in patients with cystic fibrosis. N Engl J Med 1984, 311:1653-1658.
29. Ortiz J.R., Neuzil K.M., Victor J.C., Wald A., Aitken M.L., Goss C.H. Influenza-associated cystic fibrosis pulmonary exacerbations. Chest 2010, 137:852-860.
30. Da Silva Filho L.V.R.F., Zerbinati R.M., Tateno A.F., Boas L.V., de Almeida M.B., Levi J.E., et al. The differential clinical impact of human coronavirus species in children with cystic fibrosis. J Infect Dis 2012, 206:384-388.
31. Chiu S.S., Chan K.H., Chu K.W., Kwan S.W., Guan Y., Poon L.L.M., et al. Human coronavirus NL63 infection and other coronavirus infections in children hospitalized with acute respiratory disease in Hong Kong, China. Clin Infect Dis 2005, 40:1721-1729.
32. Savolainen-Kopra C., Al-Hello H., Paananen A., Blomqvist S., Klemola P., Sobotova Z., et al. Molecular epidemiology and dual serotype specificity detection of echovirus 11 strains in Finland. Virus Res 2009, 139:32-38.
33. Tan C.Y.Q., Ninove L., Gaudart J., Nougairede A., Zandotti C., Thirion-Perrier L., et al. A retrospective overview of enterovirus infection diagnosis and molecular epidemiology in the public hospitals of Marseille, France (1985-2005). PLoS One 2011, 6:e18022.
34. Kieninger E., Singer F., Tapparel C., Alves1 M.P., Latzin1 P., Tan H-L., et al. High rhinovirus burden in lower airways of children with cystic fibrosis. Chest 2013, 143(3):782-790.
35. Brennan S., Sly P.D., Gangell C.L., Sturges N., Winfield K., Wikstrom M., et al. Alveolar macrophages and CC chemokines are increased in children with cystic fibrosis. Eur Respir J 2009, 34:655-661.
36. Willner D., Furlan M., Haynes M., Schmieder R., Angly F.E., Silva J., et al. Metagenomic analysis of respiratory tract DNA viral communities in cystic fibrosis and non-cystic fibrosis individuals. PLoS One 2009, 4:e7370.
37. Briese T., Renwick N., Venter M., Jarman R.G., Ghosh D., Köndgen S., et al. Global distribution of novel rhinovirus genotype. Emerg Infect Dis 2008, 14:944-947.
38. Gern J.E. The ABCs of rhinoviruses, wheezing, and asthma. J Virol 2010, 84:7418-7426.
39. Fancello L., Desnues C., Raoult D., Rolain J.M. Bacteriophages and diffusion of genes encoding antimicrobial resistance in cystic fibrosis sputum microbiota. J Antimicrob Chemother 2011, 66:2448-2454.