Bacteriophages and diffusion of genes encoding antimicrobial resistance in cystic fibrosis sputum microbiota

Journal of Antimicrobial Chemotherapy

Volumn 66, Issue 11, 2011, Pages 2448-2454

  Fancello, Laura ^a   Desnues, Christelle ^a   Raoult, Didier ^a   Rolain, Jean Marc ^a  

^a CNRS   (France)

Author keywords

Microbiota; Mobilome; Multidrug resistance; Phage induction; Transduction

Indexed keywords

BETA LACTAMASE; QUINOLINE DERIVED ANTIINFECTIVE AGENT; RIBOSOME DNA;

ANTIBIOTIC RESISTANCE; ARTICLE; BACTERIOPHAGE; BACTEROIDETES; CYANOBACTERIUM; CYSTIC FIBROSIS; DATA BASE; DIFFUSION; DNA SEQUENCE; ESCHERICHIA; GENE IDENTIFICATION; HUMAN; METAGENOMICS; MICROFLORA; NONHUMAN; NUCLEOTIDE SEQUENCE; PARSIMONY ANALYSIS; PHYLOGENETIC TREE; SPUTUM;

ANTI-BACTERIAL AGENTS; BACTERIOPHAGES; BACTEROIDETES; BETA-LACTAMASES; CYANOBACTERIA; CYSTIC FIBROSIS; DNA, RIBOSOMAL; DRUG RESISTANCE, MULTIPLE, BACTERIAL; ESCHERICHIA; FLUOROQUINOLONES; GENE TRANSFER, HORIZONTAL; METAGENOME; PHYLOGENY; RNA, RIBOSOMAL, 16S; SPUTUM;

EID: 80054690786     PISSN: 03057453     EISSN: 14602091     Source Type: Journal    
DOI: 10.1093/jac/dkr315     Document Type: Article

References (27)

1. Ratjen F, Doring G. Cystic fibrosis. Lancet 2003; 361: 681-9.
2. Waters V, Ratjen F. Multidrug-resistant organisms in cystic fibrosis: management and infection-control issues. Expert Rev Anti Infect Ther 2006; 4: 807-19.
3. Rolain JM, Francois P, Hernandez D et al. Genomic analysis of an emerging multiresistant Staphylococcus aureus strain rapidly spreadingin cystic fibrosis patients revealed the presence of an antibiotic inducible bacteriophage. Biol Direct 2009; 4: 1.
4. Winstanley C, Langille MG, Fothergill JL et al. Newly introduced genomic prophage islands are critical determinants of in vivo competitiveness in the Liverpool Epidemic Strain of Pseudomonas aeruginosa. Genome Res 2009; 19: 12-23.
5. Fothergill JL, Mowat E, Ledson MJ et al. Fluctuations in phenotypes and genotypes within populations of Pseudomonas aeruginosa in the cystic fibrosis lung during pulmonary exacerbations. J Med Microbiol 2010; 59: 472-81.
6. Holden MT, Seth-Smith HM, Crossman LC et al. The genome of Burkholderia cenocepacia J2315, an epidemic pathogen of cystic fibrosis patients. J Bacteriol 2008; 191: 261-77.
7. Smith EE, Buckley DG, Wu Z et al. Genetic adaptation by Pseudomonas aeruginosa to the airways of cystic fibrosis patients. Proc Natl Acad Sci USA 2006; 103: 8487-92.
8. Brockhurst MA, Buckling A, Rainey PB. The effect of a bacteriophage on diversification of the opportunistic bacterial pathogen, Pseudomonas aeruginosa. Proc Biol Sci 2005; 272: 1385-91.
9. Finnan S, Morrissey JP, O'Gara F et al. Genome diversity of Pseudomonas aeruginosa isolates from cystic fibrosis patients and the hospital environment. J Clin Microbiol 2004; 42: 5783-92.
10. Goerke C, Wirtz C, Fluckiger U et al. Extensive phage dynamics in Staphylococcus aureus contributes to adaptation to the human host during infection. Mol Microbiol 2006; 61: 1673-85.
11. Colomer-Lluch M, Jofre J, Muniesa M. Antibiotic resistance genes in the bacteriophage DNA fraction of environmental samples. PLoS ONE 2011; 6: e17549.
12. Goodman AL, Kallstrom G, Faith JJ et al. Extensive personal human gut microbiota culture collections characterized and manipulated in gnotobiotic mice. Proc Natl Acad Sci USA 2011; 108: 6252-7.
13. Goerke C, Koller J, Wolz C. Ciprofloxacin and trimethoprim cause phage induction and virulence modulation in Staphylococcus aureus. Antimicrob Agents Chemother 2006; 50: 171-7.
14. Fothergill JL, Mowat E, Walshaw MJ et al. Effect of antibiotic treatment on bacteriophage production by a cystic fibrosis epidemic strain of Pseudomonas aeruginosa. Antimicrob Agents Chemother 2011; 55: 426-8.
15. Willner D, Furlan M, Haynes M et al. Metagenomic analysis of respiratory tract DNA viral communities in cystic fibrosis and non-cystic fibrosis individuals. PLoS ONE 2009; 4: e7370.
16. Willner D, Furlan M. Deciphering the role of phage in the cystic fibrosis airway. Virulence 2010; 1: 309-13.
17. Hyatt D, Chen GL, Locascio PF et al. Prodigal: prokaryotic gene recognition and translation initiation site identification. BMC Bioinformatics 2010; 11: 119.
18. Edgar RC. MUSCLE: multiple sequence alignment with high accuracy and high throughput. Nucleic Acids Res 2004; 32: 1792-7.
19. Castresana J. Selection of conserved blocks from multiple alignments for their use in phylogenetic analysis. Mol Biol Evol 2000; 17: 540-52.
20. Guindon S, Gascuel O. A simple, fast, and accurate algorithm to estimate large phylogenies by maximum likelihood. Syst Biol 2003; 52: 696-704.
21. Tamura K, Dudley J, Nei M et al. MEGA4: Molecular Evolutionary Genetics Analysis (MEGA) software version 4.0. Mol Biol Evol 2007; 24: 1596-9.
22. Wagner PL, Waldor MK. Bacteriophage control of bacterial virulence. Infect Immun 2002; 70: 3985-93.
23. Zhang X, McDaniel AD, Wolf LE et al. Quinolone antibiotics induce Shiga toxin-encoding bacteriophages, toxin production, and death in mice. J Infect Dis 2000; 181: 664-70.
24. Matsushiro A, Sato K, Miyamoto H et al. Induction of prophages of enterohemorrhagic Escherichia coli O157:H7 with norfloxacin. J Bacteriol 1999; 181: 2257-60.
25. Bittar F, Richet H, Dubus JC et al. Molecular detection of multiple emerging pathogens in sputa from cystic fibrosis patients. PLoS ONE 2008; 3: e2908.
26. Harris JK, De Groote MA, Sagel SD et al. Molecular identification of bacteria in bronchoalveolar lavage fluid from children with cystic fibrosis. Proc Natl Acad Sci USA 2007; 104: 20529-33.
27. Ghosh D, Roy K, Williamson KE et al. Acyl-homoserine lactones can induce virus production in lysogenic bacteria: an alternative paradigm for prophage induction. Appl Environ Microbiol 2009; 75: 7142-52.