Novel role for histamine through classical H1 and H2 receptors: Regulation of leydig cell steroidogenesis and its implications for male reproductive function

Biomedical Aspects of Histamine: Current Perspectives

Volumn , Issue , 2011, Pages 383-393

  Mondillo, Carolina ^a   Pignataro, Omar Pedro ^a,b  

^a INST DE BIOL Y MED EXPERIMENTAL   (Argentina)

^b UNIVERSIDAD DE BUENOS AIRES   (Argentina)

Author keywords

Histamine; Histamine H1 receptor; Histamine H2 receptor; Leydig cell; Male reproductive function

Indexed keywords

EID: 84900284486     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1007/978-90-481-9349-3_17     Document Type: Chapter

References (52)

1. Albrecht M, Frungieri MB, Gonzalez-Calvar S, et al (2005) Evidence for a histaminergic system in the human testis. Fertil Steril 83:1060-1063
2. Almeida RG, Massoco CO, Spinosa HS, et al (1996) Perinatal astemizole exposure in the rat throughout gestation: Long-Term behavioral and anatomic effects associated with reproduction. Comp Biochem Physiol C Pharmacol Toxicol Endocrinol 114:123-127
3. Ambrosino A, Russo D, Lamanna C, et al (2003) Isoforms of nitric oxiDe synthase in the pig testis. Acta Vet BRNO 72:493-498
4. Bredt DS, Snyder SH (1994) Nitric oxide: A physiologic messenger molecule. Annu Rev Biochem 63:175-195
5. Cara AM, Lopes-Martins RA, Antunes E, et al (1995) The role of histamine in human penile erection. Br J Urol 75:220-224
6. Davidoff MS, Middendorff R, Mayer B, et al (1995) Nitric oxiDe synthase (NOS-I) in Leydig cells of the human testis. Arch Histol Cytol 58:17-30
7. Del Punta K, Charreau EH, Pignataro OP (1996) Nitric oxiDe inhibits Leydig cell steroidogenesis. Endocrinology 137:5337-5343
8. Diemer T, Allen JA, Hales KH, et al (2003) Reactive oxygen disrupts mitochondria in MA-10 tumor Leydig cells and inhibits steroidogenic acute regulatory (StAR) protein and steroidogenesis. Endocrinology 144:2882-2891
9. Falus A, Darvas S, Grossman N (2004) Histamine: Biology and medical aspects. SpringMed, Budapest
10. Franca LR, Leal MC, Sasso-Cerri E, et al (2000) Cimetidine (Tagamet) is a reproductive toxicant in male rats affecting peritubular cells. Biol Reprod 63:1403-1412
11. Gaytan F, Aceitero J, Lucena C, et al (1992) Simultaneous proliferation and differentiation of mast cells and Leydig cells in the rat testis. Are common regulatory factors involved? J Androl 13:387-397
12. Gaytan F, Carrera G, Pinilla L, et al (1989) Mast cells in the testis, epididymis and accessory glands of the rat: Effects of neonatal steroid treatment. J Androl 10:351-358
13. Herman M, Rivier C (2006) Activation of a neural brain-Testicular pathway rapidly lowers Leydig cell levels of the steroidogenic acute regulatory protein and the peripheral-Type benzodiazepine receptor while increasing levels of neuronal nitric oxiDe synthase. Endocrinology 147:624-633
14. Hough LB (2001) Genomics meets histamine receptors: New subtypes, new receptors. Mol Pharmacol 59:415-419
15. Hussein MR, Abou-Deif ES, Bedaiwy MA, et al (2005) Phenotypic characterization of the immune and mast cell infiltrates in the human testis shows normal and abnormal spermatogenesis. Fertil Steril 83:1447-1453
16. Igaz PHH (2004) Histamine receptors: H1, H2, H3, H4, and the putative Hic (intracellular) receptor. Coding genes and gene products, in silico and experimental data. In: Falus A, Darvas S, Grossman N (eds) Histamine: Biology and medical aspects, SpringMed, Budapest
17. Jaureguiberry MS, di Nunzio AS, Dattilo MA, et al (2004) Endothelin 1 and 3 enhance neuronal nitric oxiDe synthase activity through ETB receptors involving multiple signaling pathways in the rat anterior hypothalamus. Peptides 25:1133-1138
18. Joshi MS, Ferguson TB Jr, Johnson FK, et al (2007) Receptor-mediated activation of nitric oxiDe synthesis by arginine in endothelial cells. Proc Natl Acad Sci USA 104:9982-9987
19. Khan UW, Rai U (2007) Differential effects of histamine on Leydig cell and testicular macrophage activities in wall lizards: Precise role of H1/H2 receptor subtypes. J Endocrinol 194:441-448
20. Kim YC, Davies MG, Lee TH, et al (1995) Characterization and function of histamine receptors in corpus cavernosum. J Urol 153:506-510
21. Krishna A, Terranova PF (1985) Alterations in mast cell degranulation and ovarian histamine in the proestrous hamster. Biol Reprod 32:1211-1217
22. Leurs R, Smit MJ, Timmerman H (1995) Molecular pharmacological aspects of histamine receptors. Pharmacol Ther 66:413-463
23. Lima AP, Lunardi LO, Rosa ESAA (2000) Effects of castration and testosterone replacement on peritoneal histamine concentration and lung histamine concentration in pubertal male rats. J Endocrinol 167:71-75
24. MacFarland RT, Zelus BD, Beavo JA (1991) High concentrations of a cGMP-stimulated phosphodiesterase mediate ANP-induced decreases in cAMP and steroidogenesis in adrenal glomerulosa cells. J Biol Chem 266:136-142
25. Martinez AC, Garcia-Sacristan A, Rivera L, et al (2000) Biphasic response to histamine in rabbit penile dorsal artery. J Cardiovasc Pharmacol 36:737-743
26. Martinez AC, Hernandez M, Prieto D, et al (2006) Enhanced histamine-mediated contraction of rabbit penile dorsal artery in diet-induced hypercholesterolemia. Vascul Pharmacol 44:34-41
27. Mayerhofer A, Bartke A, Amador AG, et al (1989) Histamine affects testicular steroid production in the golden hamster. Endocrinology 125:2212-2214
28. Meineke V, Frungieri MB, Jessberger B, et al (2000) Human testicular mast cells contain tryptase: Increased mast cell number and altered distribution in the testes of infertile men. Fertil Steril 74:239-244
29. Mikkelsen E, Sakr AM, Jespersen LT (1984) Studies on the effect of histamine in isolated human pulmonary arteries and veins. Acta Pharmacol Toxicol (Copenh) 54:86-93
30. Moncada S, Palmer RM, Higgs EA (1991) Nitric oxide: Physiology, pathophysiology, and pharmacology. Pharmacol Rev 43:109-142
31. Mondillo C, Falus A, Pignataro O, et al (2007) Prolonged histamine deficiency in histidine decarboxylase gene knockout mice affects Leydig cell function. J Androl 28:86-91
32. Mondillo C, Pagotto RM, Piotrkowski B, et al (2009) Involvement of nitric oxiDe synthase in the mechanism of histamine-induced inhibition of Leydig cell steroidogenesis via histamine receptor subtypes in Sprague-Dawley rats. Biol Reprod 80:144-152
33. Mondillo C, Patrignani Z, Reche C, et al (2005) Dual role of histamine in modulation of Leydig cell steroidogenesis via HRH1 and HRH2 receptor subtypes. Biol Reprod 73:899-907
34. Morris SMJr, Billiar TR (1994) New insights into the regulation of inducible nitric oxiDe synthesis. Am J Physiol 266:E829-839
35. Nemetallah BR, Howell RE, Ellis LC (1983) Histamine H1 receptors and prostaglandin-histamine interactions modulating contractility of rabbit and rat testicular capsules in vitro. Biol Reprod 28:632-635
36. Nguyen T, Shapiro DA, George SR, et al (2001) Discovery of a novel member of the histamine receptor family. Mol Pharmacol 59:427-433
37. Nimmegeers S, Decaluwe K, Van De VoorDe J (2008) Characterization of the effect of histamine on mouse corpus cavernosum. Inflamm Res 57(Suppl 1):S59-S60
38. Nistal M, Santamaria L, Paniagua R (1984) Mast cells in the human testis and epididymis from birth to adulthood. Acta Anat (Basel) 119:155-160
39. Nussler AK, Billiar TR, Liu ZZ, et al (1994) Coinduction of nitric oxiDe synthase and argininosuccinate synthetase in a murine macrophage cell line. Implications for regulation of nitric oxiDe production. J Biol Chem 269:1257-1261
40. Pap E, Racz K, Kovacs JK, et al (2002) Histidine decarboxylase deficiency in gene knockout mice elevates male sex steroid production. J Endocrinol 175:193-199
41. Pár G, Szekeres-Bartho J, Buzas E, et al (2003) Impaired reproduction of histamine deficient (histidine-Decarboxylase knockout) mice is caused predominantly by a decreased male mating behavior. Am J Reprod Immunol 50:152-158
42. Paria BC, Das N, Das SK, et al (1998) Histidine decarboxylase gene in the mouse uterus is regulated by progesterone and correlates with uterine differentiation for blastocyst implantation. Endocrinology 139:3958-3966
43. Reche C, Mondillo C, Patrignani Z, et al (2003) Effects of nitric oxiDe on steroidogenesis and expression of nitric oxiDe synthase isoforms in rat Leydig cells. In: The Endocrine Society's 85th meeting. Program and abstracts: 515 The Endocrine Society, Philadelphia, PA
44. Rosselli M, Keller PJ, Dubey RK (1998) Role of nitric oxiDe in the biology, physiology and pathophysiology of reproduction. Hum Reprod Update 4:3-24
45. Safina F, Tanaka S, Inagaki M, et al (2002) Expression of L-histidine decarboxylase in mouse male germ cells. J Biol Chem 277:14211-14215
46. Schell C, Albrecht M, Mayer C, et al (2008) Exploring human testicular peritubular cells: Identification of secretory products and regulation by tumor necrosis factor-Alpha. Endocrinology 149:1678-1686
47. Schmidt G, Ahren K, Brannstrom M, et al (1987) Histamine stimulates progesterone synthesis and cyclic adenosine 3-,5-monophosphate accumulation in isolated preovulatory rat follicles. Neuroendocrinology 46:69-74
48. Tuncel N, Aydin Y, Kosar M, et al (1997) The effect of vasoactive intestinal peptiDe (VIP) on the testicular tissue histamine level of immobilized + cold stressed rats. Peptides 18:913-915
49. Tuncel N, Gurer F, Aral E, et al (1996) The effect of vasoactive intestinal peptiDe (VIP) on mast cell invasion/degranulation in testicular interstitium of immobilized + cold stressed and betaendorphin-Treated rats. Peptides 17:817-824
50. Wagner W, Ichikawa A, Tanaka S, et al (2003) Mouse mammary epithelial histamine system. J Physiol Pharmacol 54:211-223
51. Zieher LM, Debeljuk L, Iturriza F, et al (1971) Biogenic amine concentration in testes of rats at different ages. Endocrinology 88:351-354
52. Zini A, O'Bryan MK, Magid MS, et al (1996) Immunohistochemical localization of endothelial nitric oxiDe synthase in human testis, epididymis, and vas deferens suggests a possible role for nitric oxiDe in spermatogenesis, sperm maturation, and programmed cell death. Biol Reprod 55:935-941