-
1
-
-
84857192718
-
Causes and consequences of aneuploidy in cancer
-
Gordon DJ, Resio B, Pellman D. Causes and consequences of aneuploidy in cancer. Nat Rev Genet 2012;13:189-203.
-
(2012)
Nat Rev Genet
, vol.13
, pp. 189-203
-
-
Gordon, D.J.1
Resio, B.2
Pellman, D.3
-
2
-
-
0029160299
-
The checkpoint delaying anaphase in response to chromosome monoorientation ismediated by an inhibitory signal produced by unattached kinetochores
-
Rieder CL, Cole RW, Khodjakov A, Sluder G. The checkpoint delaying anaphase in response to chromosome monoorientation ismediated by an inhibitory signal produced by unattached kinetochores. J Cell Biol 1995;130:941-8.
-
(1995)
J Cell Biol
, vol.130
, pp. 941-948
-
-
Rieder, C.L.1
Cole, R.W.2
Khodjakov, A.3
Sluder, G.4
-
3
-
-
34247333444
-
The spindle-assembly checkpoint in space and time
-
DOI 10.1038/nrm2163, PII NRM2163
-
Musacchio A, Salmon ED. The spindle-assembly checkpoint in space and time. Nat Rev Mol Cell Biol 2007;8:379-93. (Pubitemid 46643240)
-
(2007)
Nature Reviews Molecular Cell Biology
, vol.8
, Issue.5
, pp. 379-393
-
-
Musacchio, A.1
Salmon, E.D.2
-
5
-
-
68249112645
-
VHL loss causes spindle misorientation and chromosome instability
-
Thoma CR, Toso A, Gutbrodt KL, Reggi SP, Frew IJ, Schraml P, et al. VHL loss causes spindle misorientation and chromosome instability. Nat Cell Biol 2009;11:994-1001.
-
(2009)
Nat Cell Biol
, vol.11
, pp. 994-1001
-
-
Thoma, C.R.1
Toso, A.2
Gutbrodt, K.L.3
Reggi, S.P.4
Frew, I.J.5
Schraml, P.6
-
6
-
-
84857996830
-
Low MAD2 expression levels associate with reduced progression-Free survival in patients with high-Grade serous epithelial ovarian cancer
-
Furlong F, Fitzpatrick P, O'Toole S, Phelan S, McGrogan B, Maguire A, et al. Low MAD2 expression levels associate with reduced progression- free survival in patients with high-grade serous epithelial ovarian cancer. J Pathol 2012;226:746-55.
-
(2012)
J Pathol
, vol.226
, pp. 746-755
-
-
Furlong, F.1
Fitzpatrick, P.2
O'Toole, S.3
Phelan, S.4
McGrogan, B.5
Maguire, A.6
-
7
-
-
80052558778
-
Overexpression of MAD2 predicts clinical outcome in primary lung cancer patients
-
Kato T, Daigo Y, Aragaki M, Ishikawa K, Sato M, Kondo S, et al. Overexpression of MAD2 predicts clinical outcome in primary lung cancer patients. Lung Cancer (Amsterdam, Netherlands) 2011;74:124-31.
-
(2011)
Lung Cancer (Amsterdam, Netherlands)
, vol.74
, pp. 124-131
-
-
Kato, T.1
Daigo, Y.2
Aragaki, M.3
Ishikawa, K.4
Sato, M.5
Kondo, S.6
-
8
-
-
67149136370
-
MAD2 as a key component of mitotic checkpoint: A probable prognostic factor for gastric cancer
-
Wang L, Yin F, Du Y, Du W, Chen B, Zhang Y, et al. MAD2 as a key component of mitotic checkpoint: a probable prognostic factor for gastric cancer. Am J Clin Pathol 2009;131:793-801.
-
(2009)
Am J Clin Pathol
, vol.131
, pp. 793-801
-
-
Wang, L.1
Yin, F.2
Du Du, Y.W.3
Chen, B.4
Zhang, Y.5
-
9
-
-
0035905811
-
MAD2 haplo-Insufficiency causes premature anaphase and chromosome instability in mammalian cells
-
DOI 10.1038/35053094
-
Michel LS, Liberal V, Chatterjee A, Kirchwegger R, Pasche B, Gerald W, et al. MAD2 haplo-insufficiency causes premature anaphase and chromosome instability in mammalian cells. Nature 2001;409:355-9. (Pubitemid 32151241)
-
(2001)
Nature
, vol.409
, Issue.6818
, pp. 355-359
-
-
Michel, L.S.1
Liberal, V.2
Chatterjee, A.3
Kirchwegger, R.4
Pasche, B.5
Gerald, W.6
Dobles, M.7
Sorger, P.K.8
Murty, V.V.V.S.9
Benezra, R.10
-
10
-
-
33845986330
-
Mad2 overexpression promotes aneuploidy and tumorigenesis in mice
-
DOI 10.1016/j.ccr.2006.10.019, PII S1535610806003710
-
Sotillo R, Hernando E, Diaz-Rodriguez E, Teruya-Feldstein J, Cordon- Cardo C, Lowe SW, et al. Mad2 overexpression promotes aneuploidy and tumorigenesis in mice. Cancer Cell 2007;11:9-23. (Pubitemid 46054519)
-
(2007)
Cancer Cell
, vol.11
, Issue.1
, pp. 9-23
-
-
Sotillo, R.1
Hernando, E.2
Diaz-Rodriguez, E.3
Teruya-Feldstein, J.4
Cordon-Cardo, C.5
Lowe, S.W.6
Benezra, R.7
-
13
-
-
47049090632
-
PVHL and PTEN tumour suppressor proteins cooperatively suppress kidney cyst formation
-
Frew IJ, Thoma CR, Georgiev S, Minola A, Hitz M, Montani M, et al.pVHL and PTEN tumour suppressor proteins cooperatively suppress kidney cyst formation. EMBO J 2008;27:1747-57.
-
(2008)
EMBO J
, vol.27
, pp. 1747-1757
-
-
Frew, I.J.1
Thoma, C.R.2
Georgiev, S.3
Minola, A.4
Hitz, M.5
Montani, M.6
-
14
-
-
84900011517
-
Tumor suppressor VHL functions in the control of mitotic fidelity
-
Hell MP, Duda M, Weber TC, Moch H, Krek W. Tumor suppressor VHL functions in the control of mitotic fidelity. Cancer Res 2014;74:2422-31.
-
(2014)
Cancer Res
, vol.74
, pp. 2422-2431
-
-
Hell, M.P.1
Duda, M.2
Weber, T.C.3
Moch, H.4
Krek, W.5
-
15
-
-
79954986879
-
An improved technique for chromosomal analysis of human ES and iPS cells
-
Moralli D, Yusuf M, Mandegar MA, Khoja S, Monaco ZL, Volpi EV. An improved technique for chromosomal analysis of human ES and iPS cells. Stem Cell Rev 2011;7:471-7.
-
(2011)
Stem Cell Rev
, vol.7
, pp. 471-477
-
-
Moralli, D.1
Yusuf, M.2
Mandegar, M.A.3
Khoja, S.4
Monaco, Z.L.5
Volpi, E.V.6
-
16
-
-
84872043569
-
Bub1 kinase activity drives error correction and mitotic checkpoint control but not tumor suppression
-
Ricke RM, Jeganathan KB, Malureanu L, Harrison AM, van Deursen JM. Bub1 kinase activity drives error correction and mitotic checkpoint control but not tumor suppression. J Cell Biol 2012;199: 931-49.
-
(2012)
J Cell Biol
, vol.199
, pp. 931-949
-
-
Ricke, R.M.1
Jeganathan, K.B.2
Malureanu, L.3
Harrison, A.M.4
Van Deursen, J.M.5
-
17
-
-
34250805982
-
MicroRNA Targeting Specificity in Mammals: Determinants beyond Seed Pairing
-
DOI 10.1016/j.molcel.2007.06.017, PII S1097276507004078
-
Grimson A, Farh KK, Johnston WK, Garrett-Engele P, Lim LP, Bartel DP. MicroRNA targeting specificity in mammals: determinants beyond seed pairing. Mol Cell 2007;27:91-105. (Pubitemid 46991392)
-
(2007)
Molecular Cell
, vol.27
, Issue.1
, pp. 91-105
-
-
Grimson, A.1
Farh, K.K.-H.2
Johnston, W.K.3
Garrett-Engele, P.4
Lim, L.P.5
Bartel, D.P.6
-
18
-
-
33747849920
-
RNAhybrid: MicroRNA target prediction easy, fast and flexible
-
Kruger J, Rehmsmeier M. RNAhybrid: microRNA target prediction easy, fast and flexible. Nucleic Acids Res 2006;34:W451-4.
-
(2006)
Nucleic Acids Res
, vol.34
-
-
Kruger, J.1
Rehmsmeier, M.2
-
19
-
-
35948984173
-
PennCNV: An integrated hidden Markov model designed for high-resolution copy number variation detection in whole-genome SNP genotyping data
-
DOI 10.1101/gr.6861907
-
Wang K, Li M, Hadley D, Liu R, Glessner J, Grant SF, et al. PennCNV: an integrated hidden Markov model designed for high-resolution copy number variation detection in whole-genome SNP genotyping data. Genome Res 2007;17:1665-74. (Pubitemid 350074862)
-
(2007)
Genome Research
, vol.17
, Issue.11
, pp. 1665-1674
-
-
Wang, K.1
Li, M.2
Hadley, D.3
Liu, R.4
Glessner, J.5
Grant, S.F.A.6
Hakonarson, H.7
Bucan, M.8
-
20
-
-
84879890360
-
Comprehensive molecular characterization of clear cell renal cell carcinoma. Nature 2013;499:43-9. 21. Mood AM. on the asymptotic efficiency of certain nonparametric twosample tests
-
Creighton CJ, Morgan M, Gunaratne PH, Wheeler DA, Gibbs RA, Robertson A, et al. Comprehensive molecular characterization of clear cell renal cell carcinoma. Nature 2013;499:43-9. 21. Mood AM. On the asymptotic efficiency of certain nonparametric twosample tests. Ann Math Stat 1954;25:514-22.
-
(1954)
Ann Math Stat
, vol.25
, pp. 514-522
-
-
Creighton, C.J.1
Morgan, M.2
Gunaratne, P.H.3
Wheeler, D.A.4
Gibbs, R.A.5
Robertson, A.6
-
21
-
-
0035912725
-
Molecular mechanisms of translation initiation in eukaryotes
-
DOI 10.1073/pnas.111145798
-
Pestova TV, Kolupaeva VG, Lomakin IB, Pilipenko EV, Shatsky IN, Agol VI, et al. Molecular mechanisms of translation initiation in eukaryotes. Proc Natl Acad Sci U S A 2001;98:7029-36. (Pubitemid 32567898)
-
(2001)
Proceedings of the National Academy of Sciences of the United States of America
, vol.98
, Issue.13
, pp. 7029-7036
-
-
Pestova, T.V.1
Kolupaeva, V.G.2
Lomakin, I.B.3
Pilipenko, E.V.4
Shatsky, I.N.5
Agol, V.I.6
Hellen, C.U.T.7
-
22
-
-
78751477191
-
Gene silencing by microRNAs: Contributions of translational repression and mRNA decay
-
Huntzinger E, Izaurralde E. Gene silencing by microRNAs: contributions of translational repression and mRNA decay. Nat Rev Genet 2011;12:99-110.
-
(2011)
Nat Rev Genet
, vol.12
, pp. 99-110
-
-
Huntzinger, E.1
Izaurralde, E.2
-
23
-
-
84861866572
-
The mechanics of miRNA-mediated gene silencing: A look under the hood of miRISC
-
Fabian MR, Sonenberg N. The mechanics of miRNA-mediated gene silencing: a look under the hood of miRISC. Nat Struct Mol Biol 2012;19:586-93.
-
(2012)
Nat Struct Mol Biol
, vol.19
, pp. 586-593
-
-
Fabian, M.R.1
Sonenberg, N.2
-
24
-
-
81755162750
-
P31(comet) acts to ensure timely spindle checkpoint silencing subsequent to kinetochore attachment
-
Hagan RS, Manak MS, Buch HK, Meier MG, Meraldi P, Shah JV, et al. p31(comet) acts to ensure timely spindle checkpoint silencing subsequent to kinetochore attachment. Mol Biol Cell 2011;22:4236-46.
-
(2011)
Mol Biol Cell
, vol.22
, pp. 4236-4246
-
-
Hagan, R.S.1
Manak, M.S.2
Buch, H.K.3
Meier, M.G.4
Meraldi, P.5
Shah, J.V.6
-
25
-
-
0036291255
-
Epithelial-specific Cre/lox recombination in the developing kidney and genitourinary tract
-
DOI 10.1097/01.ASN.0000016444.90348.50
-
Shao X, Somlo S, Igarashi P. Epithelial-specific Cre/lox recombination in the developing kidney and genitourinary tract. J Am Soc Nephrol 2002;13:1837-46. (Pubitemid 34700608)
-
(2002)
Journal of the American Society of Nephrology
, vol.13
, Issue.7
, pp. 1837-1846
-
-
Shao, X.1
Somlo, S.2
Igarashi, P.3
-
26
-
-
66349100709
-
Patterns of gene expression and copy-number alterations in vonhippel lindau disease-associated and sporadic clear cell carcinoma of the kidney
-
Beroukhim R, Brunet JP, Di Napoli A, Mertz KD, Seeley A, Pires MM, et al. Patterns of gene expression and copy-number alterations in vonhippel lindau disease-associated and sporadic clear cell carcinoma of the kidney. Cancer Res 2009;69:4674-81.
-
(2009)
Cancer Res
, vol.69
, pp. 4674-4681
-
-
Beroukhim, R.1
Brunet, J.P.2
Di Napoli, A.3
Mertz, K.D.4
Seeley, A.5
Pires, M.M.6
-
27
-
-
77950502115
-
A hierarchy of self-renewing tumor-initiating cell types in glioblastoma
-
Chen R, Nishimura MC, Bumbaca SM, Kharbanda S, Forrest WF, Kasman IM, et al. A hierarchy of self-renewing tumor-initiating cell types in glioblastoma. Cancer Cell 2010;17:362-75.
-
(2010)
Cancer Cell
, vol.17
, pp. 362-375
-
-
Chen, R.1
Nishimura, M.C.2
Bumbaca, S.M.3
Kharbanda, S.4
Forrest, W.F.5
Kasman, I.M.6
-
29
-
-
84862701358
-
Genome-Wide microRNA expression analysis of clear cell renal cell carcinoma by next generation deep sequencing
-
Osanto S, Qin Y, Buermans HP, Berkers J, Lerut E, Goeman JJ, et al. Genome-wide microRNA expression analysis of clear cell renal cell carcinoma by next generation deep sequencing. PLoS ONE 2012;7: e38298.
-
(2012)
PLoS ONE
, vol.7
-
-
Osanto, S.1
Qin, Y.2
Buermans, H.P.3
Berkers, J.4
Lerut, E.5
Goeman, J.J.6
-
30
-
-
84868371027
-
Integrative genome-Wide expression profiling identifies three distinct molecular subgroups of renal cell carcinoma with different patient outcome
-
Beleut M, Zimmermann P, Baudis M, Bruni N, Buhlmann P, Laule O, et al. Integrative genome-wide expression profiling identifies three distinct molecular subgroups of renal cell carcinoma with different patient outcome. BMC Cancer 2012;12:310.
-
(2012)
BMC Cancer
, vol.12
, pp. 310
-
-
Beleut, M.1
Zimmermann, P.2
Baudis, M.3
Bruni, N.4
Buhlmann, P.5
Laule, O.6
-
31
-
-
42749092812
-
No somatic mutations detected in the Mad2 gene in 658 human tumors
-
Ruddy DA, Gorbatcheva B, Yarbrough G, Schlegel R, Monahan JE. No somatic mutations detected in the Mad2 gene in 658 human tumors. Mutat Res 2008;641:61-3.
-
(2008)
Mutat Res
, vol.641
, pp. 61-63
-
-
Ruddy, D.A.1
Gorbatcheva, B.2
Yarbrough, G.3
Schlegel, R.4
Monahan, J.E.5
-
32
-
-
77949773695
-
Mad2-Inducedchromosome instability leads to lung tumour relapse after oncogene withdrawal
-
Sotillo R, Schvartzman JM, Socci ND, Benezra R. Mad2-inducedchromosome instability leads to lung tumour relapse after oncogene withdrawal. Nature 2010;464:436-40.
-
(2010)
Nature
, vol.464
, pp. 436-440
-
-
Sotillo, R.1
Schvartzman, J.M.2
Socci, N.D.3
Benezra, R.4
-
33
-
-
80052266532
-
MicroRNAs can generate thresholds in target gene expression
-
Mukherji S, Ebert MS, Zheng GX, Tsang JS, Sharp PA, van Oudenaarden A. MicroRNAs can generate thresholds in target gene expression. Nat Genet 2011;43:854-9.
-
(2011)
Nat Genet
, vol.43
, pp. 854-859
-
-
Mukherji, S.1
Ebert, M.S.2
Zheng, G.X.3
Tsang, J.S.4
Sharp, P.A.5
Van Oudenaarden, A.6
-
34
-
-
84887255409
-
The spindle assembly checkpoint works like a rheostat rather than a toggle switch
-
Collin P, Nashchekina O, Walker R, Pines J. The spindle assembly checkpoint works like a rheostat rather than a toggle switch. Nat Cell Biol 2013;15:1378-85.
-
(2013)
Nat Cell Biol
, vol.15
, pp. 1378-1385
-
-
Collin, P.1
Nashchekina, O.2
Walker, R.3
Pines, J.4
-
35
-
-
84887260003
-
Determinants of robustness in spindle assembly checkpoint signalling
-
Heinrich S, Geissen EM, Kamenz J, Trautmann S, Widmer C, Drewe P, et al. Determinants of robustness in spindle assembly checkpoint signalling. Nat Cell Biol 2013;15:1328-39.
-
(2013)
Nat Cell Biol
, vol.15
, pp. 1328-1339
-
-
Heinrich, S.1
Geissen, E.M.2
Kamenz, J.3
Trautmann, S.4
Widmer, C.5
Drewe, P.6
-
36
-
-
84887235321
-
Kinetic framework of spindle assembly checkpoint signalling
-
Dick AE, Gerlich DW. Kinetic framework of spindle assembly checkpoint signalling. Nat Cell Biol 2013;15:1370-7.
-
(2013)
Nat Cell Biol
, vol.15
, pp. 1370-1377
-
-
Dick, A.E.1
Gerlich, D.W.2
-
37
-
-
78649806686
-
MicroRNA (miRNA)-Mediated interaction between leukemia/lymphoma-Related factor (LRF) and alternative splicing factor/splicing factor 2 (ASF/SF2) affects mouse embryonic fibroblast senescence and apoptosis
-
Verduci L, Simili M, Rizzo M, Mercatanti A, Evangelista M, Mariani L, et al. MicroRNA (miRNA)-mediated interaction between leukemia/lymphoma-related factor (LRF) and alternative splicing factor/splicing factor 2 (ASF/SF2) affects mouse embryonic fibroblast senescence and apoptosis. J Biol Chem 2010;285: 39551-63.
-
(2010)
J Biol Chem
, vol.285
, pp. 39551-39563
-
-
Verduci, L.1
Simili, M.2
Rizzo, M.3
Mercatanti, A.4
Evangelista, M.5
Mariani, L.6
-
38
-
-
57749113609
-
Protooncogene FBI-1 (Pokemon/ZBTB7A) represses transcription of the tumor suppressor Rb gene via binding competition with Sp1 and recruitment of co-Repressors
-
Jeon BN, Yoo JY, Choi WI, Lee CE, Yoon HG, Hur MW. Protooncogene FBI-1 (Pokemon/ZBTB7A) represses transcription of the tumor suppressor Rb gene via binding competition with Sp1 and recruitment of co-repressors. J Biol Chem 2008;283: 33199-210.
-
(2008)
J Biol Chem
, vol.283
, pp. 33199-33210
-
-
Jeon, B.N.1
Yoo, J.Y.2
Choi, W.I.3
Lee, C.E.4
Yoon, H.G.5
Hur, M.W.6
-
39
-
-
33947528891
-
Von Hippel-Lindau disease
-
Kaelin WG. Von Hippel-Lindau disease. Annu Rev Pathol 2007;2: 145-73.
-
(2007)
Annu Rev Pathol
, vol.2
, pp. 145-173
-
-
Kaelin, W.G.1
-
40
-
-
84862988411
-
BAP1 loss defines a new class of renal cell carcinoma
-
Pena-Llopis S, Vega-Rubin-De-Celis S, Liao A, Leng N, Pavia-Jimenez A, Wang S, et al. BAP1 loss defines a new class of renal cell carcinoma. Nat Genet 2012;44:751-9.
-
(2012)
Nat Genet
, vol.44
, pp. 751-759
-
-
Pena-Llopis, S.1
Vega-Rubin-De-Celis, S.2
Liao, A.3
Leng, N.4
Pavia-Jimenez, A.5
Wang, S.6
-
41
-
-
79251635938
-
Exome sequencing identifies frequent mutation of the SWI/SNF complex gene PBRM1 in renal carcinoma
-
Varela I, Tarpey P, Raine K, Huang D,Ong CK, Stephens P, et al. Exome sequencing identifies frequent mutation of the SWI/SNF complex gene PBRM1 in renal carcinoma. Nature 2011;469:539-42.
-
(2011)
Nature
, vol.469
, pp. 539-542
-
-
Varela, I.1
Tarpey, P.2
Raine, K.3
Huang, D.4
Ong, C.K.5
Stephens, P.6
-
42
-
-
0034625268
-
Chromosome missegregation and apoptosis in mice lacking the mitotic checkpoint protein Mad2
-
Dobles M, Liberal V, Scott ML, Benezra R, Sorger PK. Chromosome missegregation and apoptosis in mice lacking the mitotic checkpoint protein Mad2. Cell 2000;101:635-45.
-
(2000)
Cell
, vol.101
, pp. 635-645
-
-
Dobles, M.1
Liberal, V.2
Scott, M.L.3
Benezra, R.4
Sorger, P.K.5
-
43
-
-
84871945452
-
Altered microRNA expression associated withchromosomal changes contributes to cervical carcinogenesis
-
Wilting SM, Snijders PJ, Verlaat W, Jaspers A, van de Wiel MA, van Wieringen WN, et al. Altered microRNA expression associated withchromosomal changes contributes to cervical carcinogenesis. Oncogene 2013;32:106-16.
-
(2013)
Oncogene
, vol.32
, pp. 106-116
-
-
Wilting, S.M.1
Snijders, P.J.2
Verlaat, W.3
Jaspers, A.4
Van De Wiel, M.A.5
Van Wieringen, W.N.6
-
44
-
-
77950824571
-
Identification and functional characterization of microRNAs involved in the malignant progression of gliomas
-
(Zurich, Switzerland)
-
Malzkorn B, Wolter M, Liesenberg F, Grzendowski M, Stuhler K, Meyer HE, et al. Identification and functional characterization of microRNAs involved in the malignant progression of gliomas. Brain Pathol (Zurich, Switzerland) 2010;20:539-50.
-
(2010)
Brain Pathol
, vol.20
, pp. 539-550
-
-
Malzkorn, B.1
Wolter, M.2
Liesenberg, F.3
Grzendowski, M.4
Stuhler, K.5
Meyer, H.E.6
-
45
-
-
84855222216
-
MicroRNA expression profiles inhuman colorectal cancers with brain metastases
-
Li Z, Gu X, Fang Y, Xiang J, Chen Z. microRNA expression profiles inhuman colorectal cancers with brain metastases. Oncol Lett 2012;3: 346-50.
-
(2012)
Oncol Lett
, vol.3
, pp. 346-350
-
-
Li, Z.1
Gu, X.2
Fang, Y.3
Xiang, J.4
Chen, Z.5
-
46
-
-
84862831034
-
Strand-Specific mir-28-5p and mir-28-3p have distinct effects in colorectal cancer cells
-
Almeida MI, Nicoloso MS, Zeng L, Ivan C, Spizzo R, Gafa R, et al. Strand-specific miR-28-5p and miR-28-3p have distinct effects in colorectal cancer cells. Gastroenterology 2012;142:886-96 e9.
-
(2012)
Gastroenterology
, vol.142
-
-
Almeida, M.I.1
Nicoloso, M.S.2
Zeng, L.3
Ivan, C.4
Spizzo, R.5
Gafa, R.6
|