Silica nanoparticle-crosslinked thermosensitive hybrid hydrogels as potential drug-release carriers

Polymer Journal

Volumn 46, Issue 5, 2014, Pages 293-300

  Alam, Md Ashraful ^a,b   Takafuji, Makoto ^a   Ihara, Hirotaka ^a,c  

^a KUMAMOTO UNIVERSITY   (Japan)

^b NOAKHALI SCIENCE AND TECHNOLOGY UNIVERSITY   (Bangladesh)

^c Kumamoto Institute for Photo electro Organics (PHOENICS)   (Japan)

Author keywords

colloidal silica; controlled release; drug delivery; multiple cross linking point; polymer network; swelling; thermosensitive hydrogels

Indexed keywords

ACRYLIC MONOMERS; CAFFEINE; CHAINS; COPOLYMERS; CROSSLINKING; DRUG DELIVERY; MIXING; SWELLING;

COLLOIDAL SILICA; CONTROLLED RELEASE; MULTIPLE CROSS-LINKING POINT; POLYMER NETWORKS; THERMO-SENSITIVE HYDROGEL;

HYDROGELS;

EID: 84900002900     PISSN: 00323896     EISSN: 13490540     Source Type: Journal    
DOI: 10.1038/pj.2014.2     Document Type: Article

References (46)

1. Peppas, N. A., Bures, P., Leobandung, W. & Ichikawa, H. Hydrogels in pharmaceutical formulations. Eur. J. Pharm. Biopharm. 50, 27-46 (2000). (Pubitemid 30326687)
2. Liu, X. M., Wang, L. S., Wang, L., Huang, J. C. & He, C. B. The effect of salt and pH on the phase-transition behaviors of temperature-sensitive copolymers based on N-isopropylacrylamide. Biomaterials 25, 5659-5666 (2004). (Pubitemid 38680494)
3. Hirokawa, Y. & Tanaka, T. Volume phase transition in a non-ionic gel. J. Chem. Phys. 81, 6379-6380 (1984).
4. Kim, S. J., Shin, S. R., Lee, J. H., Lee, S. H. & Kim, S. I. Electrical response characterization of chitosan/polyacrylonitrile hydrogel in NaCl solutions. J. Appl. Polym. Sci. 90, 91-96 (2003). (Pubitemid 37025007)
5. Khare, A. R. & Peppas, N. A. Swelling/deswelling of anionic copolymer gels. Biomaterials 16, 559-567 (1995).
6. Zhang, X. Z., Zhuo, R. X., Cui, J. Z. & Zhang, J. T. A novel thermo-responsive drug delivery system with positive controlled release. Int. J. Pharm. 235, 43-50 (2002).
7. Zhang, X. Z., Wu, D. Q. & Chu, C. C. Synthesis, characterization and controlled drug release of thermosensitive IPN?PNIPAAm hydrogels. Biomaterials 25, 3793-3805 (2004).
8. Deng, K., Tian, H., Zhang, P., Zhong, H., Ren, X. & Wang, H. pH-temperature responsive poly(HPA-Co-AMHS) hydrogel as a potential drug-release carrier. J. Appl. Polym. Sci. 114, 176-184 (2009).
9. Wang, K., Fu, Q., Chen, X., Gao, Y. & Dong, K. Preparation and characterization of pH-sensitive hydrogel for drug delivery system. RSC Adv 2, 7772-7780 (2012).
10. Osada, Y., Okuzaki, H. & Hori, H. A polymer gel with electrically driven motility. Nature 355, 242-244 (1992).
11. Kurisawa, M., Yokoyama, M. & Okano, T. Gene expression control by temperature with thermo-responsive polymeric gene carriers. J. Controlled Release 69, 127-137 (2000).
12. Okano, T., Bae, Y. H., Jacobs, H. & Kim, S. W. Thermally on-off switching polymers for drug permeation and release. J. Controlled Release 11, 255-265 (1990). (Pubitemid 20070103)
13. Zhang, N., Liu, M., Shen, Y., Chen, J., Dai, L. & Gao, C. Preparation, properties, and drug release of thermo- and pH-sensitive poly((2-dimethylamino)ethyl methacrylate)/poly(N, N-dimethylacrylamide) semi-IPN hydrogels. J. Mater. Sci. 46, 1523-1534 (2011).
14. Okahata, Y., Noguchi, H. & Seki, T. Thermoselective permeation from a polymer-grafted capsule membrane. Macromolecules 19, 493-494 (1986).
15. Tanaka, Y., Kagamin, Y., Matsuda, A. & Osada, Y. Thermoreversible transition of tensile modulus of hydrogel with ordered aggregates. Macromolecules 28, 2574-2576 (1995).
16. Zhang, J. & Peppas, N. A. Morphology of poly(methacrylic acid)/poly(N-isopropyl acrylamide) interpenetrating polymeric networks. J. Biomater. Sci. Polym. Ed. 5, 511-525 (2002). (Pubitemid 34846120)
17. de Sousa, A., Maria, D. A., de Sousa, R. G. & de Sousa, E. M. B. Synthesis and characterization of mesoporous silica/poly(N-isopropylacrylamide) functional hybrid useful for drug delivery. J. Mater. Sci. 45, 1478-1486 (2010).
18. Geever, L. M., Nugent, M. J. D. & Higginbotham, C. L. The effect of salts and pH buffer solutions on the phase transition temperature and swelling of thermoresponsive pseudogels based on N-isopropylacrylamide. J. Mater. Sci 42, 9845-9854 (2007). (Pubitemid 47476490)
19. Anseth, K. S., Metters, A. T., Bryant, S. J., Martens, P. J., Elisseeff, J. H. & Bowman, C. N. In situ forming degradable networks and their application in tissue engineering and drug delivery. J. Controlled Release 78, 199-209 (2002). (Pubitemid 34081865)
20. Bravo, S. A., Lamas, M. C. & Salomon, C. J. In-vitro studies of diclofenac sodium controlled-release from biopolymeric hydrophilic matrices. J. Pharm. Sci. 5, 213-219 (2002). (Pubitemid 37207247)
21. Kim, S. W., Bae, Y. H. & Okano, T. Hydrogels: swelling, drug loading and release. Pharm. Res. 9, 283-290 (1992).
22. Zhang, J. T., Keller, T. F., Bhat, R., Garipcan, B. & Jandt, K. D. A novel two-level microstructured poly(N-isopropylacrylamide) hydrogel for controlled release. Acta. Biomater. 6, 3890-3898 (2010).
23. Ng, L. T. & Swami, S. IPNs based on chitosan with NVP and NVP/HEMA synthesised through photoinitiator-free photopolymerisation technique for biomedical applications. Carbohydr. Polym 60, 523-528 (2005). (Pubitemid 40744094)
24. Mathews, A. S., Cho, W. J., Kim, I. & Ha, C. S. Thermally responsive poly[Nisopropylacrylamide-co-2-hydroxyethylacrylate] colloidal crystals included in β-cyclodextrin for controlled drug delivery. J. Appl. Polym. Sci. 113, 1680-1689 (2009).
25. Geever, L., Cooney, C., Devine, D., Devery, S., Nugent, M. & Higginbotham, C. Negative temperature sensitive hydrogels in controlled drug delivery. Macromol. Symp. 266, 53-58 (2008).
26. Takafuji, M., Yamada, S. & Ihara, H. Strategy for preparation of hybrid polymer hydrogels using silica nanoparticles as multifunctional crosslinking points. Chem. Commun 47, 1024-1026 (2011).
27. Alam, M. A., Takafuji, M. & Ihara, H. Thermosensitive hybrid hydrogels with silica nanoparticle-cross-linked polymer networks. J. Colloid Interface Sci. 405, 109-117 (2013).
28. Makino, K., Hiyoshi, J. & Ohshima, H. Kinetics of swelling and shrinking of poly (N-isopropylacrylamide) hydrogels at different temperatures. Colloids Surf. B 19, 197-204 (2000). (Pubitemid 30658007)
29. Zhang, X. Z., Yang, Y. Y., Chung, T. S. & Ma, K. X. Preparation and characterization of fast response macroporous poly(N-isopropylacrylamide) hydrogels. Langmuir. 17, 6094-6099 (2001).
30. Ham, M. J. & Kim, Y. H. Property modulation of Poly(N- isopropylacrylamide) Hydrogels by Incorporation of Modified Silica. Polym. Eng. Sci. 48, 2439-2445 (2008).
31. Huang, W. J. & Lee, W. F. Effect of silane coupling agent on swelling behaviors and mechanical properties of thermosensitive hybrid gels. J. Appl. Polym. Sci. 111, 2025-2034 (2009).
32. Ngadaonye, J. I., Geever, L. M., Cloonan, M. O. & Higginbotham, C. L. Photopolymerised thermo-responsive poly(N, N-diethylacrylamide)-based copolymer hydrogels for potential drug delivery applications. J. Polym. Res. 19, 9822-9836 (2012).
33. Mohapatra, R., Ray, D., Swain, A. K., Pal, T. K. & Sahoo, P. K. Release study of alfuzosin hydrochloride loaded to novel hydrogel P(HEMA-co-AA). J. Appl. Polym. Sci. 108, 380-386 (2008). (Pubitemid 351363303)
34. Hoffman, A. S. Hydrogels for biomedical applications. Adv. Drug Deliv. Rev. 54, 3-12 (2002). (Pubitemid 34081178)
35. Lee, W. F. & Lin, Y. H. Thermoreversible hydrogels. XIX. Synthesis and swelling behavior and drug release behavior for the N-isopropylacrylamide/ poly(ethylene glycol) methylether acrylate copolymeric hydrogels. J. Appl. Polym. Sci 90, 1683-1691 (2003).
36. Brazel, C. S. & Peppas, N. A. Mechanisms of solute and drug transport in relaxing, swellable, hydrophilic glassy polymers. Polymer (Guildf). 40, 3383-3398 (1999). (Pubitemid 30122557)
37. Shi, J., Alves, N. M. & Mano, J. F. Drug release of pH/temperature-responsive calcium alginate/poly(N-isopropylacrylamide) semi-IPN beads. Macromol. Biosci. 6, 358-363 (2006). (Pubitemid 43829064)
38. Guo, B.-L. & Gao, Q.-Y. Preparation and properties of a pH/temperature-responsive carboxymethyl chitosan/poly(N-isopropylacrylamide) semi-IPN hydrogel for oral delivery of drugs. Carbohydr. Res. 342, 2416-2422 (2007). (Pubitemid 47525506)
39. Peppas, N. A. & Franson, N. M. The swelling interphase number as a criterion for prediction of diffusional solute release mechanisms in swellable polymers. J. Polym. Sci. Phys. Ed. 21, 983-997 (1983).
40. Haraguchi, K., Takehisa, T. & Fan, S. Effects of clay content on the properties of nanocomposite hydrogels composed of poly(N-isopropylacrylamide) and clay. Macromolecules 35, 10162-10171 (2002).
41. Zhang, X. Z. & Zhuo, R. X. Dynamic properties of temperature- sensitive poly(N-isopropylacrylamide) gel cross-linked through siloxane linkage. Langmuir 17, 12-16 (2001).
42. Kaneko, Y., Sakai, K., Kikuchi, A., Yoshida, R., Sakurai, Y. & Okano, T. Influence of freely mobile grafted chain length on dynamic properties of comb-type grafted poly(N-isopropylacrylamide) hydrogels. Macromolecules 28, 7717-7723 (1995).
43. Zhang, J. T., Xue, Y. N., Gao, F. Z., Huang, S. W. & Zhuo, R. X. Preparation of temperature-sensitive poly(N-isopropylacrylamide)/?-cyclodextrin- grafted polyethylenimine hydrogels for drug delivery. J. Appl. Polym. Sci. 108, 3031-3037 (2008).
44. Zhao, S., Cao, M., Li, H., Li, L. & Xu, W. Synthesis and characterization of thermosensitive semi-IPN hydrogels based on poly(ethylene glycol)-co-poly(e-caprolactone) macromer, N-isopropylacrylamide, and sodium alginate. Carbohydr. Res. 345, 425-431 (2010).
45. Ritger, P. L. & Peppas, N. A. A simple equation for description of solute release I. Fickian and non-Fickian release from non-swellable devices in the form of slabs, spheres, cylinders or discs. J. Controlled Release 5, 23-26 (1987).
46. Miao, Z. M., Cheng, S. X., Zhang, X. Z. & Zhuo, R. X. Study on drug release behaviors of poly-?,?-[N-(2-hydroxyethyl)-L-aspartamide]-g-poly(3- caprolactone) nano- and microparticles. Biomacromolecules 7, 2020-2026 (2006).