Higher levels of advanced glycation endproducts in human carotid atherosclerotic plaques are associated with a rupture-prone phenotype

European Heart Journal

Volumn 35, Issue 17, 2014, Pages 1137-1146

  Hanssen, Nordin M J ^a,b   Wouters, Kristiaan ^a,b   Huijberts, Maya S ^a,b   Gijbels, Marion J ^a,b,c   Sluimer, Judith C ^a,b   Scheijen, Jean L J M ^a   Heeneman, Sylvia ^a,b   Biessen, Erik A L ^a,b   Daemen, Mat J A P ^a,c   Brownlee, Michael ^d   De Kleijn, Dominique P ^e,f   Stehouwer, Coen D A ^a,b   Pasterkamp, Gerard ^e   Schalkwijk, Casper G ^a,b  

^a MAASTRICHT UNIVERSITY   (Netherlands)

^b MAASTRICHT UNIVERSITY MEDICAL CENTER   (Netherlands)

^c ACADEMIC MEDICAL CENTER   (Netherlands)

^d ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

^e UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^f NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

Author keywords

Advanced glycation endproducts; Atherosclerosis; Cell death; Glyoxalase; Macrophage; Plaque rupture

Indexed keywords

5 HYDROXY 5 METHYLIMIDAZOLONE; 6 N CARBOXYMETHYLLYSINE; ADVANCED GLYCATION END PRODUCT; BIOLOGICAL MARKER; CASPASE 3; GELATINASE B; GLYOXALASE; GLYOXALASE 1; INTERLEUKIN 8; MESSENGER RNA; METHYLGLYOXAL; MONOCYTE CHEMOTACTIC PROTEIN 1; UNCLASSIFIED DRUG; TUMOR NECROSIS FACTOR ALPHA;

AGED; ANIMAL CELL; APOPTOSIS; ARTICLE; CAROTID ATHEROSCLEROSIS; CAROTID ENDARTERECTOMY; CONTROLLED STUDY; DISEASE COURSE; FEMALE; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; INFLAMMATION; MACROPHAGE; MAJOR CLINICAL STUDY; MALE; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; TANDEM MASS SPECTROMETRY; ANEURYSM RUPTURE; ANIMAL; ATHEROSCLEROTIC PLAQUE; C57BL MOUSE; CAROTID ARTERY DISEASE; CELL HYPOXIA; DRUG EFFECTS; METABOLISM; MONONUCLEAR CELL; PHYSIOLOGY;

AGED; ANEURYSM, RUPTURED; ANIMALS; APOPTOSIS; CAROTID ARTERY DISEASES; CELL HYPOXIA; GLYCOSYLATION END PRODUCTS, ADVANCED; HUMANS; LEUKOCYTES, MONONUCLEAR; MACROPHAGES; MALE; MICE, INBRED C57BL; PHENOTYPE; PLAQUE, ATHEROSCLEROTIC; RNA, MESSENGER; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84900001245     PISSN: 0195668X     EISSN: 15229645     Source Type: Journal    
DOI: 10.1093/eurheartj/eht402     Document Type: Article

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