Lithium chloride inhibits TGF-β1-induced myofibroblast transdifferentiation via PI3K/Akt pathway in cultured fibroblasts from Tenon's capsule of the human eye

Biotechnology Letters

Volumn 36, Issue 6, 2014, Pages 1217-1224

  Chung, Eun Jee ^a   Sohn, Yong Ho ^b   Kwon, So Hyun ^b   Jung, Sun Ah ^b   Lee, Joon H ^a,b  

^a Konyang University College of Medicine   (South Korea)

^b National Health Insurance Corporation   (South Korea)

Author keywords

Fibroblasts; Lithium chloride; Myofibroblasts; Post operative scarring; Tenon's capsule; Transdifferentiation; Transforming growth factors (TGF 1)

Indexed keywords

CELL CULTURE; FIBROBLASTS;

MYOFIBROBLASTS; POST-OPERATIVE SCARRING; TENON'S CAPSULE; TRANS DIFFERENTIATIONS; TRANSFORMING GROWTH FACTORS;

LITHIUM CHLORIDE;

LITHIUM CHLORIDE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; TRANSFORMING GROWTH FACTOR BETA;

CELL DIFFERENTIATION; DRUG EFFECTS; FIBROBLAST; GLAUCOMA; HUMAN; METABOLISM; MYOFIBROBLAST; PHYSIOLOGY; SCAR; SIGNAL TRANSDUCTION; TENON CAPSULE;

CELL DIFFERENTIATION; CICATRIX; FIBROBLASTS; GLAUCOMA; HUMANS; LITHIUM CHLORIDE; MYOFIBROBLASTS; PHOSPHATIDYLINOSITOL 3-KINASES; PROTO-ONCOGENE PROTEINS C-AKT; SIGNAL TRANSDUCTION; TENON CAPSULE; TRANSFORMING GROWTH FACTOR BETA;

EID: 84899988690     PISSN: 01415492     EISSN: 15736776     Source Type: Journal    
DOI: 10.1007/s10529-014-1487-4     Document Type: Article

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