Comparison of counter-current chromatography and preparative high performance liquid chromatography applied to separating minor impurities in drug preparations

Journal of Chromatography A

Volumn 1344, Issue , 2014, Pages 51-58

  Li, Shucai ^a   Wang, Wenwen ^a   Tang, Huan ^a   Chen, Kai ^a   Yang, Jianhong ^a   He, Linhong ^a   Ye, Haoyu ^a   Peng, Aihua ^a   Chen, Lijuan ^a  

^a SICHUAN UNIVERSITY   (China)

Author keywords

CCC; Honokiol; Impurities; Preparative HPLC; Quercetin

Indexed keywords

CHROMATOGRAPHY; DRUG PRODUCTS; FLAVONOIDS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IMPURITIES; PHENOLS; SEPARATION; THROUGHPUT;

CCC; COUNTERCURRENT CHROMATOGRAPHY; DRUG DISCOVERY PROCESS; HONOKIOL; ISOLATION AND PURIFICATION; PERFORMANCE PARAMETERS; PREPARATIVE HPLC; QUERCETIN;

LOADING;

HONOKIOL; QUERCETIN;

ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; CONTROLLED STUDY; COUNTER CURRENT CHROMATOGRAPHY; DRUG DETERMINATION; DRUG IMPURITY; DRUG SOLUBILITY; DRUG STRUCTURE; FLOW RATE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; INTERMETHOD COMPARISON; PHASE SEPARATION; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; STRUCTURE ANALYSIS;

CCC; HONOKIOL; IMPURITIES; PREPARATIVE HPLC; QUERCETIN;

ANTINEOPLASTIC AGENTS; BIPHENYL COMPOUNDS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; COUNTERCURRENT DISTRIBUTION; DRUG COMPOUNDING; DRUG CONTAMINATION; LIGNANS; QUERCETIN; SOLVENTS;

EID: 84899987371     PISSN: 00219673     EISSN: 18733778     Source Type: Journal    
DOI: 10.1016/j.chroma.2014.04.004     Document Type: Article

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