Endogenous dopamine is involved in the herbicide paraquat-induced dopaminergic cell death

Toxicological Sciences

Volumn 139, Issue 2, 2014, Pages 466-478

  Izumi, Yasuhiko ^a   Ezumi, Masayuki ^a   Takada Takatori, Yuki ^b   Akaike, Akinori ^a,c   Kume, Toshiaki ^a  

^a KYOTO UNIVERSITY   (Japan)

^b DOSHISHA WOMEN'S COLLEGE OF LIBERAL ARTS   (Japan)

^c NAGOYA UNIVERSITY   (Japan)

Author keywords

Dopamine; Paraquat; Parkinson disease; Quinoprotein; Tyrosine hydroxylase

Indexed keywords

ASCORBIC ACID; CYSTEINE; DOPAMINE; PARAQUAT; PROTEIN DERIVATIVE; QUINONE DERIVATIVE; QUINOPROTEIN; TYROSINE 3 MONOOXYGENASE; UNCLASSIFIED DRUG; AMINE OXIDASE (FLAVIN CONTAINING); AROMATIC LEVO AMINO ACID DECARBOXYLASE; CATECHOL METHYLTRANSFERASE; HERBICIDE;

ANIMAL CELL; ARTICLE; CELL LEVEL; CELL VACUOLE; COMPLEX FORMATION; CONJUGATION; CONTROLLED STUDY; CYTOSOL; CYTOTOXICITY; DELAYED NEUROTOXICITY; DISEASE ASSOCIATION; DOPAMINERGIC NERVE CELL; ENZYME ACTIVITY; ENZYME INHIBITION; INTRACELLULAR SPACE; NERVE CELL NECROSIS; NEUROPATHOLOGY; NONHUMAN; PARAQUAT POISONING; PC12 CELL LINE; RAT; ANIMAL; ANTAGONISTS AND INHIBITORS; CELL SURVIVAL; CULTURE TECHNIQUE; CYTOPLASM VESICLE; DRUG EFFECTS; IMMUNOHISTOCHEMISTRY; METABOLISM; TOXICITY; WESTERN BLOTTING;

ANIMALS; AROMATIC-L-AMINO-ACID DECARBOXYLASES; BLOTTING, WESTERN; CATECHOL O-METHYLTRANSFERASE; CELL CULTURE TECHNIQUES; CELL SURVIVAL; CYTOPLASMIC VESICLES; CYTOSOL; DOPAMINE; HERBICIDES; IMMUNOHISTOCHEMISTRY; MONOAMINE OXIDASE; PARAQUAT; PC12 CELLS; RATS; TYROSINE 3-MONOOXYGENASE;

EID: 84899981052     PISSN: 10966080     EISSN: 10960929     Source Type: Journal    
DOI: 10.1093/toxsci/kfu054     Document Type: Article

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