Paraquat neurotoxicity is mediated by the dopamine transporter and organic cation transporter-3

Proceedings of the National Academy of Sciences of the United States of America

Volumn 108, Issue 51, 2011, Pages 20766-20771

  Rappold, Phillip M ^a   Cui, Mei ^a,c   Chesser, Adrianne S ^a   Tibbett, Jacqueline ^a   Grima, Jonathan C ^a   Duan, Lihua ^b   Sen, Namita ^b   Javitch, Jonathan A ^b   Tieua, Kim ^a  

^a UNIVERSITY OF ROCHESTER MEDICAL CENTER   (United States)

^b Och Spine at New York Presbyterian Hospitals   (United States)

^c FUDAN UNIVERSITY   (China)

Author keywords

Astrocytes; Extraneuronal monoamine transporter; In vivo microdialysis; Neurodegeneration

Indexed keywords

DOPAMINE TRANSPORTER; MONOVALENT CATION; OCTAMER TRANSCRIPTION FACTOR 4; ORGANIC CATION TRANSPORTER 3; OXIDOREDUCTASE; PARAQUAT; REDUCING AGENT;

ANIMAL CELL; ANIMAL CELL CULTURE; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BIOACCUMULATION; CONTROLLED STUDY; CYTOTOXICITY; DOPAMINERGIC NERVE CELL; MICROGLIA; MOUSE; MOUSE MUTANT; NERVE CELL CULTURE; NEUROMODULATION; NEUROTOXICITY; NIGRONEOSTRIATAL SYSTEM; NONHUMAN; OXIDATIVE STRESS; PARAQUAT POISONING; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION;

ANIMALS; CATIONS; CELL SURVIVAL; DOPAMINE PLASMA MEMBRANE TRANSPORT PROTEINS; DOSE-RESPONSE RELATIONSHIP, DRUG; MICE; MICE, TRANSGENIC; MICRODIALYSIS; NADPH OXIDASE; NEURODEGENERATIVE DISEASES; NEUROTOXICITY SYNDROMES; NEUROTOXINS; ORGANIC ANION TRANSPORTERS, SODIUM-INDEPENDENT; OXIDATION-REDUCTION; OXIDATIVE STRESS; PARAQUAT; SUBSTANTIA NIGRA;

MUS;

EID: 84855515680     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1115141108     Document Type: Article

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