Isoenzyme-specific regulation of cardiac Kv1.5/Kvβ1.2 ion channel complex by protein kinase C: Central role of PKCβII

Naunyn-Schmiedeberg's Archives of Pharmacology

Volumn 387, Issue 5, 2014, Pages 469-476

  Fischer, Fathima ^a   Vonderlin, Nadine ^a   Seyler, Claudia ^a   Zitron, Edgar ^a,b   Korkmaz, Sevil ^a   Szabó, Gábor ^a   Thomas, Dierk ^a   Katus, Hugo A ^a,b   Scholz, Eberhard P ^a  

^a UNIVERSITY HOSPITAL HEIDELBERG   (Germany)

^b DZHK GERMAN CENTRE FOR CARDIOVASCULAR RESEARCH   (Germany)

Author keywords

Adrenergic regulation; Isoenzymes; Kv1.5; Protein kinase C; Repolarization; Ultrarapid delayed rectifier current

Indexed keywords

2 [1 (3 AMIDINOTHIOPROPYL) 1H INDOL 3 YL] 3 (1 METHYL 1H INDOL 3 YL)MALEIMIDE; INGENOL; ISOENZYME; PHORBOL 13 ACETATE 12 MYRISTATE; POTASSIUM CHANNEL KV1.2; POTASSIUM CHANNEL KV1.2 BETA; POTASSIUM CHANNEL KV1.5; PROTEIN KINASE C; PROTEIN KINASE C ALPHA; PROTEIN KINASE C ALPHA INHIBITOR; PROTEIN KINASE C BETA; PROTEIN KINASE C BETA INHIBITOR; STAUROSPORINE; UNCLASSIFIED DRUG; PROTEIN BINDING;

ANIMAL CELL; ARTICLE; COMPLEX FORMATION; CONTROLLED STUDY; ELECTRODE; ENZYME ACTIVATION; ENZYME INHIBITION; FEMALE; HETEROLOGOUS EXPRESSION; ION CURRENT; NONHUMAN; OOCYTE; REGULATORY MECHANISM; VOLTAGE CLAMP TECHNIQUE; XENOPUS; ANIMAL; HEART MUSCLE; HUMAN; METABOLISM; PHYSIOLOGY;

ANIMALS; HUMANS; ISOENZYMES; KV1.2 POTASSIUM CHANNEL; KV1.5 POTASSIUM CHANNEL; MYOCARDIUM; PROTEIN BINDING; PROTEIN KINASE C BETA; TETRADECANOYLPHORBOL ACETATE; XENOPUS;

EID: 84899973346     PISSN: 00281298     EISSN: 14321912     Source Type: Journal    
DOI: 10.1007/s00210-014-0965-5     Document Type: Article

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