The physiological role of riboflavin transporter and involvement of FMN-riboswitch in its gene expression in Corynebacterium glutamicum

Applied Microbiology and Biotechnology

Volumn 98, Issue 9, 2014, Pages 4159-4168

  Takemoto, Norihiko ^a   Tanaka, Yuya ^a   Inui, Masayuki ^a   Yukawa, Hideaki ^a  

^a RESEARCH INSTITUTE OF INNOVATIVE TECHNOLOGY FOR THE EARTH   (Japan)

Author keywords

Corynebacterium glutamicum; FMN; Riboflavin; Riboswitch

Indexed keywords

ENCODING (SYMBOLS); INDUSTRIAL CHEMICALS; SUBSTRATES;

CORYNEBACTERIUM GLUTAMICUM; FLAVIN ADENINE DINUCLEOTIDE; FLAVIN MONO NUCLEOTIDES (FMN); FMN; INDUSTRIAL PRODUCTION; INTRACELLULAR CONCENTRATION; RIBOFLAVIN; RIBOSWITCHES;

GENE EXPRESSION;

FLAVINE ADENINE NUCLEOTIDE; FLAVINE MONONUCLEOTIDE; GUANOSINE TRIPHOSPHATE CYCLOHYDROLASE II; RIBOFLAVIN; 5' UNTRANSLATED REGION; BACTERIAL PROTEIN; CARRIER PROTEIN; CULTURE MEDIUM; RIBOSWITCH;

5' UNTRANSLATED REGION; ARTICLE; BACTERIAL GROWTH; BIOSYNTHESIS; CELL GROWTH; CORYNEBACTERIUM GLUTAMICUM; ESCHERICHIA COLI; GENE CONTROL; GENE EXPRESSION; GENE MUTATION; GENE SYNTHESIS; NONHUMAN; OPTICAL DENSITY; PROTEIN EXPRESSION; RIBOSWITCH; CHEMISTRY; CULTURE MEDIUM; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENE INACTIVATION; GENETICS; GROWTH, DEVELOPMENT AND AGING; METABOLISM;

CORYNEBACTERIUM GLUTAMICUM;

5' UNTRANSLATED REGIONS; BACTERIAL PROTEINS; CORYNEBACTERIUM GLUTAMICUM; CULTURE MEDIA; FLAVIN MONONUCLEOTIDE; GENE EXPRESSION; GENE EXPRESSION REGULATION, BACTERIAL; GENE KNOCKOUT TECHNIQUES; MEMBRANE TRANSPORT PROTEINS; RIBOFLAVIN; RIBOSWITCH;

EID: 84899968266     PISSN: 01757598     EISSN: 14320614     Source Type: Journal    
DOI: 10.1007/s00253-014-5570-5     Document Type: Article

References (36)

1. Abbas CA, Sibirny AA (2011) Genetic control of biosynthesis and transport of riboflavin and flavin nucleotides and construction of robust biotechnological producers. Microbiol Mol Biol Rev 75(2):321-360. doi:10.1128/MMBR.00030-10
2. Brune I, Brinkrolf K, Kalinowski J, Puhler A, Tauch A (2005) The individual and common repertoire of DNA-binding transcriptional regulators of Corynebacterium glutamicum, Corynebacterium efficiens, Corynebacterium diphtheriae and Corynebacterium jeikeium deduced from the complete genome sequences. BMC Genomics 6:86. doi:10.1186/1471-2164-6-86
3. Burgess CM, Slotboom DJ, Geertsma ER, Duurkens RH, Poolman B, van Sinderen D (2006) The riboflavin transporter RibU in Lactococcus lactis: molecular characterization of gene expression and the transportmechanism. J Bacteriol 188(8):2752-2760. doi:10.1128/JB.188.8.2752-2760.2006
4. Ely F, Nunes JE, Schroeder EK, Frazzon J, PalmaMS, Santos DS, Basso LA (2008) The Mycobacterium tuberculosis Rv2540c DNA sequence encodes a bifunctional chorismate synthase. BMC Biochem 9:13. doi:10.1186/1471-2091-9-13
5. Eschenbrenner M, Chlumsky LJ, Khanna P, Strasser F, Jorns MS (2001) Organization of the multiple coenzymes and subunits and role of the covalent flavin link in the complex heterotetrameric sarcosine oxidase. Biochemistry (Mosc) 40(18):5352-5367 (Pubitemid 32458235)
6. Hermann T (2003) Industrial production of amino acids by coryneform bacteria. J Biotechnol 104(1-3):155-172
7. Hill CM, Pang SS, Duggleby RG (1997) Purification of Escherichia coli acetohydroxyacid synthase isoenzyme II and reconstitution of active enzyme fromits individual pure subunits. BiochemJ 327(Pt 3):891-898 (Pubitemid 27487699)
8. Hollands K, Proshkin S, Sklyarova S, Epshtein V, Mironov A, Nudler E, Groisman EA (2012) Riboswitch control of Rho-dependent transcription termination. Proc Natl Acad Sci U S A 109(14):5376-5381. doi:10.1073/pnas. 1112211109
9. Ikeda M, Nakagawa S (2003) The Corynebacterium glutamicum genome: features and impacts on biotechnological processes. Appl Microbiol Biotechnol 62(2-3):99-109. doi:10.1007/s00253-003-1328-1 (Pubitemid 36995160)
10. Inui M, Kawaguchi H, Murakami S, Vertès AA, Yukawa H (2004a) Metabolic engineering of Corynebacterium glutamicum for fuel ethanol production under oxygen-deprivation conditions. J Mol Microbiol Biotechnol 8(4):243-254. doi:10.1159/000086705 (Pubitemid 41368969)
11. Inui M, Murakami S, Okino S, Kawaguchi H, Vertès AA, Yukawa H (2004b)Metabolic analysis of Corynebacterium glutamicum during lactate and succinate productions under oxygen deprivation conditions. J Mol Microbiol Biotechnol 7(4):182-196. doi:10.1159/000079827 (Pubitemid 39294707)
12. Inui M, Suda M, Okino S, Nonaka H, Puskas LG, Vertès AA, Yukawa H (2007) Transcriptional profiling of Corynebacterium glutamicum metabolism during organic acid production under oxygen deprivation conditions. Microbiology 153(Pt 8):2491-2504. doi:10.1099/mic.0.2006/005587-0 (Pubitemid 47262039)
13. Joo YC, Jeong KW, Yeom SJ, Kim YS, Kim Y, Oh DK (2012) Biochemical characterization and FAD-binding analysis of oleate hydratase from Macrococcus caseolyticus. Biochimie 94(3):907-915. doi:10.1016/j.biochi.2011.12.011
14. Kalinowski J, Bathe B, Bartels D, Bischoff N, Bott M, Burkovski A, Dusch N, Eggeling L, Eikmanns BJ, Gaigalat L, Goesmann A, Hartmann M, Huthmacher K, Kramer R, Linke B, McHardy AC, Meyer F, Mockel B, Pfefferle W, Puhler A, Rey DA, Ruckert C, Rupp O, Sahm H, Wendisch VF, Wiegrabe I, Tauch A (2003) The complete Corynebacterium glutamicum ATCC 13032 genome sequence and its impact on the production of L-aspartate-derived amino acids and vitamins. J Biotechnol 104(1-3):5-25 (Pubitemid 37011345)
15. Kinoshita S, Udaka S, Shimono M (2004) Studies on the amino acid fermentation. Part 1. Production of L-glutamic acid by various microorganisms. J Gen Appl Microbiol 50(6):331-343 (Pubitemid 40667507)
16. Koizumi S, Teshiba S (1998) Riboflavin biosynthetic genes of Corynebacterium ammoniagenes. J Ferment Bioeng 86(1):130-133 (Pubitemid 28381532)
17. Macheroux P, Kappes B, Ealick SE (2011) Flavogenomics-a genomic and structural view of flavin-dependent proteins. FEBS J 278(15):2625-2634. doi:10.1111/j.1742-4658.2011.08202.x
18. Mansjo M, Johansson J (2011) The riboflavin analog roseoflavin targets an FMN-riboswitch and blocks Listeria monocytogenes growth, but also stimulates virulence gene-expression and infection. RNA Biol 8(4):674-680. doi:10.4161/rna.8.4.15586
19. Mironov VN, Kraev AS, Chikindas ML, Chernov BK, Stepanov AI, Skryabin KG (1994) Functional organization of the riboflavin biosynthesis operon from Bacillus subtilis SHgw. Mol Gen Genet 242(2):201-208 (Pubitemid 24043221)
20. Molenaar D, van der Rest ME, Petrovic S (1998) Biochemical and genetic characterization of the membrane-associated malate dehydrogenase (acceptor) from Corynebacterium glutamicum. Eur J Biochem 254(2):395-403 (Pubitemid 28289397)
21. Mörtl S, Fischer M, Richter G, Tack J, Weinkauf S, Bacher A (1996) Biosynthesis of riboflavin. Lumazine synthase of Escherichia coli. J Biol Chem 271(52):33201-33207 (Pubitemid 27010126)
22. Nantapong N, Otofuji A,Migita CT, Adachi O, Toyama H,Matsushita K (2005) Electron transfer ability from NADH to menaquinone and from NADPH to oxygen of type II NADH dehydrogenase of Corynebacterium glutamicum. Biosci Biotechnol Biochem 69(1):149-159 (Pubitemid 40383495)
23. Okino S, Inui M, Yukawa H (2005) Production of organic acids by Corynebacterium glutamicum under oxygen deprivation. Appl Microbiol Biotechnol 68(4):475-480. doi:10.1007/s00253-005-1900-y (Pubitemid 41549991)
24. Okino S, Noburyu R, Suda M, Jojima T, Inui M, Yukawa H (2008a) An efficient succinic acid production process in a metabolically engineered Corynebacterium glutamicum strain. Appl Microbiol Biotechnol 81(3):459-464. doi:10.1007/s00253-008-1668-y
25. Okino S, Suda M, Fujikura K, Inui M, Yukawa H (2008b) Production of D-lactic acid by Corynebacterium glutamicum under oxygen deprivation. Appl Microbiol Biotechnol 78(3):449-454. doi:10.1007/s00253-007-1336-7
26. Pedrolli DB, Matern A,Wang J, Ester M, Siedler K, Breaker R, Mack M (2012) A highly specialized flavin mononucleotide riboswitch responds differently to similar ligands and confers roseoflavin resistance to Streptomyces davawensis. Nucleic Acids Res 40(17):8662-8673. doi:10.1093/nar/gks616
27. Richter G, Volk R, Krieger C, Lahm HW, Rothlisberger U, Bacher A (1992) Biosynthesis of riboflavin: cloning, sequencing, and expression of the gene coding for 3,4-dihydroxy-2-butanone 4-phosphate synthase of Escherichia coli. J Bacteriol 174(12):4050-4056
28. Richter G, Ritz H, Katzenmeier G, Volk R, Kohnle A, Lottspeich F, Allendorf D, Bacher A (1993) Biosynthesis of riboflavin: cloning, sequencing, mapping, and expression of the gene coding for GTP cyclohydrolase II in Escherichia coli. J Bacteriol 175(13):4045-4051 (Pubitemid 23206898)
29. Richter G, Fischer M, Krieger C, Eberhardt S, Luttgen H, Gerstenschlager I, Bacher A (1997) Biosynthesis of riboflavin: characterization of the bifunctional deaminase-reductase of Escherichia coli and Bacillus subtilis. J Bacteriol 179(6):2022-2028 (Pubitemid 27123087)
30. Tanaka Y, Ehira S, Teramoto H, Inui M, Yukawa H (2012) Coordinated regulation of gnd, which encodes 6-phosphogluconate dehydrogenase, by the two transcriptional regulators GntR1 and RamA in Corynebacterium glutamicum. J Bacteriol 194(23):6527-6536. doi:10.1128/jb.01635-12
31. Teramoto H, Suda M, Inui M, Yukawa H (2010) Regulation of the expression of genes involved in NAD de novo biosynthesis in Corynebacterium glutamicum. Appl Environ Microbiol 76(16):5488-5495. doi:10.1128/AEM.00906-10
32. Vitreschak AG, Rodionov DA, Mironov AA, Gelfand MS (2002) Regulation of riboflavin biosynthesis and transport genes in bacteria by transcriptional and translational attenuation. Nucleic Acids Res 30(14):3141-3151 (Pubitemid 34846178)
33. Vogl C, Grill S, Schilling O, Stulke J, Mack M, Stolz J (2007) Characterization of riboflavin (vitamin B2) transport proteins from Bacillus subtilis and Corynebacterium glutamicum. J Bacteriol 189(20):7367-7375. doi:10.1128/JB.00590-07 (Pubitemid 47557352)
34. von Canstein H, Ogawa J, Shimizu S, Lloyd JR (2008) Secretion of flavins by Shewanella species and their role in extracellular electron transfer. Appl Environ Microbiol 74(3):615-623. doi:10.1128/AEM.01387-07 (Pubitemid 351225711)
35. Winkler WC, Cohen-Chalamish S, Breaker RR (2002) An mRNA structure that controls gene expression by binding FMN. Proc Natl Acad Sci U S A 99(25):15908-15913. doi:10.1073/pnas.212628899 (Pubitemid 35462722)
36. Yukawa H, Omumasaba CA, Nonaka H, Kos P, Okai N, Suzuki N, Suda M, Tsuge Y, Watanabe J, Ikeda Y, Vertès AA, Inui M (2007) Comparative analysis of the Corynebacterium glutamicum group and complete genome sequence of strain R.Microbiology 153(Pt 4):1042-1058. doi:10.1099/mic.0.2006/003657-0 (Pubitemid 46605802)