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Angewandte Chemie - International Edition

Volumn 53, Issue 19, 2014, Pages 4840-4844

Mechanistic insights into polycycle formation by reductive cyclization in ikarugamycin biosynthesis

(11) Zhang, Guangtao a Zhang, Wenjun a Zhang, Qingbo a Shi, Ting b Ma, Liang a Zhu, Yiguang a Li, Sumei a Zhang, Haibo a Zhao, Yi Lei b Shi, Rong c Zhang, Changsheng a

a SOUTH CHINA SEA INSTITUTE OF OCEANOLOGY (China)

b Shanghai Jiao Tong University (China)

c UNIVERSITÉ LAVAL (Canada)

Author keywords

biosynthesis; heterologous expression; ikarugamycin; polycyclic tetramate macrolactams; reductive cyclization

Indexed keywords

ADDITION REACTIONS; BIOCHEMISTRY; BIOSYNTHESIS;

BIOCHEMICAL MECHANISMS; ENZYMATIC MECHANISMS; FIVE-MEMBERED RINGS; HETEROLOGOUS EXPRESSION; IKARUGAMYCIN; POLYCYCLIC RING SYSTEMS; POLYCYCLIC TETRAMATE MACROLACTAMS; REDUCTIVE CYCLIZATION;

CYCLIZATION;

IKARUGAMYCIN; LACTAM;

CYCLIZATION; METABOLISM; OXIDATION REDUCTION REACTION;

CYCLIZATION; LACTAMS; OXIDATION-REDUCTION;

EID: 84899911031 PISSN: 14337851 EISSN: 15213773 Source Type: Journal
DOI: 10.1002/anie.201402078 Document Type: Article

Times cited : (82)

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