-
1
-
-
0029038986
-
Analysis of estrogen receptor function in vitro reveals three distinct classes of antiestrogens
-
D.P. McDonnell, D.L. Clemm, T. Hermann, M.E. Goldman, and J.W. Pike Analysis of estrogen receptor function in vitro reveals three distinct classes of antiestrogens Mol. Endocrinol. 9 1995 659 669
-
(1995)
Mol. Endocrinol.
, vol.9
, pp. 659-669
-
-
McDonnell, D.P.1
Clemm, D.L.2
Hermann, T.3
Goldman, M.E.4
Pike, J.W.5
-
2
-
-
0030946198
-
Coactivator and corepressor regulation of the agonist/antagonist activity of the mixed antiestrogen, 4-hydroxytamoxifen
-
C.L. Smith, Z. Nawaz, and B.W. O'Malley Coactivator and corepressor regulation of the agonist/antagonist activity of the mixed antiestrogen, 4-hydroxytamoxifen Mol. Endocrinol. 11 1997 657 666
-
(1997)
Mol. Endocrinol.
, vol.11
, pp. 657-666
-
-
Smith, C.L.1
Nawaz, Z.2
O'Malley, B.W.3
-
3
-
-
0032446607
-
The structural basis of estrogen receptor/coactivator recognition and the antagonism of this interaction by tamoxifen
-
A.K. Shiau, D. Barstad, P.M. Loria, L. Cheng, P.J. Kushner, D.A. Agard, and G.L. Greene The structural basis of estrogen receptor/coactivator recognition and the antagonism of this interaction by tamoxifen Cell 95 1998 927 937
-
(1998)
Cell
, vol.95
, pp. 927-937
-
-
Shiau, A.K.1
Barstad, D.2
Loria, P.M.3
Cheng, L.4
Kushner, P.J.5
Agard, D.A.6
Greene, G.L.7
-
4
-
-
84876883246
-
The discovery and development of selective estrogen receptor modulators (SERMs) for clinical practice
-
P.Y. Maximov, T.M. Lee, and V.C. Jordan The discovery and development of selective estrogen receptor modulators (SERMs) for clinical practice Curr. Clin. Pharmacol. 8 2013 135 155
-
(2013)
Curr. Clin. Pharmacol.
, vol.8
, pp. 135-155
-
-
Maximov, P.Y.1
Lee, T.M.2
Jordan, V.C.3
-
5
-
-
67149102658
-
New selective estrogen and androgen receptor modulators
-
B.L. Clarke, and S. Khosla New selective estrogen and androgen receptor modulators Curr. Opin. Rheumatol. 21 2009 374 379
-
(2009)
Curr. Opin. Rheumatol.
, vol.21
, pp. 374-379
-
-
Clarke, B.L.1
Khosla, S.2
-
6
-
-
73649084450
-
Molecular mechanism of the inhibition of estradiol-induced endometrial epithelial cell proliferation by clomiphene citrate
-
M. Amita, T. Takahashi, S. Tsutsumi, T. Ohta, K. Takata, N. Henmi, S. Hara, H. Igarashi, K. Takahashi, and H. Kurachi Molecular mechanism of the inhibition of estradiol-induced endometrial epithelial cell proliferation by clomiphene citrate Endocrinology 151 2010 394 405
-
(2010)
Endocrinology
, vol.151
, pp. 394-405
-
-
Amita, M.1
Takahashi, T.2
Tsutsumi, S.3
Ohta, T.4
Takata, K.5
Henmi, N.6
Hara, S.7
Igarashi, H.8
Takahashi, K.9
Kurachi, H.10
-
7
-
-
33646133406
-
The expanding cosmos of nuclear receptor coactivators
-
D.M. Lonard, and B.W. O'Malley The expanding cosmos of nuclear receptor coactivators Cell 125 2006 411 414
-
(2006)
Cell
, vol.125
, pp. 411-414
-
-
Lonard, D.M.1
O'Malley, B.W.2
-
8
-
-
0033775525
-
Molecular mechanisms of selective estrogen receptor modulator (SERM) action
-
M. Dutertre, and C.L. Smith Molecular mechanisms of selective estrogen receptor modulator (SERM) action J. Pharmacol. Exp. Ther. 295 2000 431 437
-
(2000)
J. Pharmacol. Exp. Ther.
, vol.295
, pp. 431-437
-
-
Dutertre, M.1
Smith, C.L.2
-
9
-
-
67649574704
-
Designing the ideal selective estrogen receptor modulator - An achievable goal?
-
H.S. Taylor Designing the ideal selective estrogen receptor modulator - an achievable goal? Menopause 16 2009 609 615
-
(2009)
Menopause
, vol.16
, pp. 609-615
-
-
Taylor, H.S.1
-
10
-
-
1542344018
-
Estradiol and selective estrogen receptor modulators differentially regulate target genes with estrogen receptors alpha and beta
-
M.K. Tee, I. Rogatsky, C. Tzagarakis-Foster, A. Cvoro, J. An, R.J. Christy, K.R. Yamamoto, and D.C. Leitman Estradiol and selective estrogen receptor modulators differentially regulate target genes with estrogen receptors alpha and beta Mol. Biol. Cell 15 2004 1262 1272
-
(2004)
Mol. Biol. Cell
, vol.15
, pp. 1262-1272
-
-
Tee, M.K.1
Rogatsky, I.2
Tzagarakis-Foster, C.3
Cvoro, A.4
An, J.5
Christy, R.J.6
Yamamoto, K.R.7
Leitman, D.C.8
-
11
-
-
4344632533
-
The molecular determinants of estrogen receptor pharmacology
-
D.P. McDonnell The molecular determinants of estrogen receptor pharmacology Maturitas 48 Suppl. 1 2004 S7 S12
-
(2004)
Maturitas
, vol.48
, Issue.SUPPL. 1
-
-
McDonnell, D.P.1
-
12
-
-
0037434618
-
Selective estrogen-receptor modulators - Mechanisms of action and application to clinical practice
-
B.L. Riggs, and L.C. Hartmann Selective estrogen-receptor modulators - mechanisms of action and application to clinical practice N. Engl. J. Med. 348 2003 618 629
-
(2003)
N. Engl. J. Med.
, vol.348
, pp. 618-629
-
-
Riggs, B.L.1
Hartmann, L.C.2
-
13
-
-
30344479480
-
Coregulators in nuclear estrogen receptor action: From concept to therapeutic targeting
-
J.M. Hall, and D.P. McDonnell Coregulators in nuclear estrogen receptor action: from concept to therapeutic targeting Mol. Interv. 5 2005 343 357
-
(2005)
Mol. Interv.
, vol.5
, pp. 343-357
-
-
Hall, J.M.1
McDonnell, D.P.2
-
14
-
-
15444368857
-
Mechanisms of estrogen receptor signaling: Convergence of genomic and nongenomic actions on target genes
-
L. Bjornstrom, and M. Sjoberg Mechanisms of estrogen receptor signaling: convergence of genomic and nongenomic actions on target genes Mol. Endocrinol. 19 2005 833 842
-
(2005)
Mol. Endocrinol.
, vol.19
, pp. 833-842
-
-
Bjornstrom, L.1
Sjoberg, M.2
-
15
-
-
84894615646
-
Clinical effects of selective estrogen receptor modulators on vulvar and vaginal atrophy
-
(Epub ahead of print, June 18)
-
J.V. Pinkerton, and F.Z. Stanczyk Clinical effects of selective estrogen receptor modulators on vulvar and vaginal atrophy Menopause 2013 (Epub ahead of print, June 18)
-
(2013)
Menopause
-
-
Pinkerton, J.V.1
Stanczyk, F.Z.2
-
16
-
-
84866395340
-
Bazedoxifene/conjugated estrogens for menopausal symptom treatment and osteoporosis prevention
-
J.V. Pinkerton, J.H. Pickar, J. Racketa, and S. Mirkin Bazedoxifene/conjugated estrogens for menopausal symptom treatment and osteoporosis prevention Climacteric 15 2012 411 418
-
(2012)
Climacteric
, vol.15
, pp. 411-418
-
-
Pinkerton, J.V.1
Pickar, J.H.2
Racketa, J.3
Mirkin, S.4
-
17
-
-
77952228433
-
Endometrial safety: A key hurdle for selective estrogen receptor modulators in development
-
J.V. Pinkerton, and S.R. Goldstein Endometrial safety: a key hurdle for selective estrogen receptor modulators in development Menopause 17 2010 642 653
-
(2010)
Menopause
, vol.17
, pp. 642-653
-
-
Pinkerton, J.V.1
Goldstein, S.R.2
-
18
-
-
84871489412
-
The molecular mechanisms underlying the pharmacological actions of estrogens, SERMs and oxysterols: Implications for the treatment and prevention of osteoporosis
-
E.R. Nelson, S.E. Wardell, and D.P. McDonnell The molecular mechanisms underlying the pharmacological actions of estrogens, SERMs and oxysterols: implications for the treatment and prevention of osteoporosis Bone 53 2013 42 50
-
(2013)
Bone
, vol.53
, pp. 42-50
-
-
Nelson, E.R.1
Wardell, S.E.2
McDonnell, D.P.3
-
19
-
-
77349090257
-
Lasofoxifene in postmenopausal women with osteoporosis
-
S.R. Cummings, K. Ensrud, P.D. Delmas, A.Z. LaCroix, S. Vukicevic, D.M. Reid, S. Goldstein, U. Sriram, A. Lee, J. Thompson, R.A. Armstrong, D.D. Thompson, T. Powles, J. Zanchetta, D. Kendler, P. Neven, and R. Eastell Lasofoxifene in postmenopausal women with osteoporosis N. Engl. J. Med. 362 2010 686 696
-
(2010)
N. Engl. J. Med.
, vol.362
, pp. 686-696
-
-
Cummings, S.R.1
Ensrud, K.2
Delmas, P.D.3
Lacroix, A.Z.4
Vukicevic, S.5
Reid, D.M.6
Goldstein, S.7
Sriram, U.8
Lee, A.9
Thompson, J.10
Armstrong, R.A.11
Thompson, D.D.12
Powles, T.13
Zanchetta, J.14
Kendler, D.15
Neven, P.16
Eastell, R.17
-
20
-
-
0032537396
-
Tamoxifen for early breast cancer: An overview of the randomised trials. Early Breast Cancer Trialists' Collaborative Group
-
Tamoxifen for early breast cancer: an overview of the randomised trials. Early Breast Cancer Trialists' Collaborative Group Lancet 351 1998 1451 1467
-
(1998)
Lancet
, vol.351
, pp. 1451-1467
-
-
-
21
-
-
0033575083
-
The effect of raloxifene on risk of breast cancer in postmenopausal women: Results from the MORE randomized trial
-
S.R. Cummings, S. Eckert, K.A. Krueger, D. Grady, T.J. Powles, J.A. Cauley, L. Norton, T. Nickelsen, N.H. Bjarnason, M. Morrow, M.E. Lippman, D. Black, J.E. Glusman, A. Costa, and V.C. Jordan The effect of raloxifene on risk of breast cancer in postmenopausal women: results from the MORE randomized trial JAMA 281 1999 2189 2197
-
(1999)
JAMA
, vol.281
, pp. 2189-2197
-
-
Cummings, S.R.1
Eckert, S.2
Krueger, K.A.3
Grady, D.4
Powles, T.J.5
Cauley, J.A.6
Norton, L.7
Nickelsen, T.8
Bjarnason, N.H.9
Morrow, M.10
Lippman, M.E.11
Black, D.12
Glusman, J.E.13
Costa, A.14
Jordan, V.C.15
-
22
-
-
10644283864
-
Continuing outcomes relevant to Evista: Breast cancer incidence in postmenopausal osteoporotic women in a randomized trial of raloxifene
-
S. Martino, J.A. Cauley, E. Barrett-Connor, T.J. Powles, J. Mershon, D. Disch, R.J. Secrest, S.R. Cummings, and CORE Investigators Continuing outcomes relevant to Evista: breast cancer incidence in postmenopausal osteoporotic women in a randomized trial of raloxifene J. Natl. Cancer Inst. 96 2004 1751 1761
-
(2004)
J. Natl. Cancer Inst.
, vol.96
, pp. 1751-1761
-
-
Martino, S.1
Cauley, J.A.2
Barrett-Connor, E.3
Powles, T.J.4
Mershon, J.5
Disch, D.6
Secrest, R.J.7
Cummings, S.R.8
Investigators, C.9
-
23
-
-
23844531615
-
Bazedoxifene acetate: A selective estrogen receptor modulator with improved selectivity
-
B.S. Komm, Y.P. Kharode, P.V. Bodine, H.A. Harris, C.P. Miller, and C.R. Lyttle Bazedoxifene acetate: a selective estrogen receptor modulator with improved selectivity Endocrinology 146 2005 3999 4008
-
(2005)
Endocrinology
, vol.146
, pp. 3999-4008
-
-
Komm, B.S.1
Kharode, Y.P.2
Bodine, P.V.3
Harris, H.A.4
Miller, C.P.5
Lyttle, C.R.6
-
24
-
-
33745249570
-
Effects of tamoxifen vs raloxifene on the risk of developing invasive breast cancer and other disease outcomes: The NSABP Study of Tamoxifen and Raloxifene (STAR) P-2 trial
-
V.G. Vogel, J.P. Costantino, D.L. Wickerham, W.M. Cronin, R.S. Cecchini, J.N. Atkins, T.B. Bevers, L. Fehrenbacher, E.R. Pajon Jr., J.L. Wade III, A. Robidoux, R.G. Margolese, J. James, S.M. Lippman, C.D. Runowicz, P.A. Ganz, S.E. Reis, W. Caskill-Stevens, L.G. Ford, V.C. Jordan, and N. Wolmark Effects of tamoxifen vs raloxifene on the risk of developing invasive breast cancer and other disease outcomes: the NSABP Study of Tamoxifen and Raloxifene (STAR) P-2 trial JAMA 295 2006 2727 2741
-
(2006)
JAMA
, vol.295
, pp. 2727-2741
-
-
Vogel, V.G.1
Costantino, J.P.2
Wickerham, D.L.3
Cronin, W.M.4
Cecchini, R.S.5
Atkins, J.N.6
Bevers, T.B.7
Fehrenbacher, L.8
Pajon, Jr.E.R.9
Wade III, J.L.10
Robidoux, A.11
Margolese, R.G.12
James, J.13
Lippman, S.M.14
Runowicz, C.D.15
Ganz, P.A.16
Reis, S.E.17
Caskill-Stevens, W.18
Ford, L.G.19
Jordan, V.C.20
Wolmark, N.21
more..
-
25
-
-
84862191487
-
A comparison of survival outcomes and side effects of toremifene or tamoxifen therapy in premenopausal estrogen and progesterone receptor positive breast cancer patients: A retrospective cohort study
-
R. Gu, W. Jia, Y. Zeng, N. Rao, Y. Hu, S. Li, J. Wu, L. Jin, L. Chen, M. Long, K. Chen, L. Chen, Q. Xiao, M. Wu, E. Song, and F. Su A comparison of survival outcomes and side effects of toremifene or tamoxifen therapy in premenopausal estrogen and progesterone receptor positive breast cancer patients: a retrospective cohort study BMC Cancer 12 2012 161
-
(2012)
BMC Cancer
, vol.12
, pp. 161
-
-
Gu, R.1
Jia, W.2
Zeng, Y.3
Rao, N.4
Hu, Y.5
Li, S.6
Wu, J.7
Jin, L.8
Chen, L.9
Long, M.10
Chen, K.11
Chen, L.12
Xiao, Q.13
Wu, M.14
Song, E.15
Su, F.16
-
26
-
-
0034907007
-
In vitro and in vivo biologic effects of Ospemifene (FC-1271a) in breast cancer
-
T.L. Taras, G.T. Wurz, and M.W. DeGregorio In vitro and in vivo biologic effects of Ospemifene (FC-1271a) in breast cancer J. Steroid Biochem. Mol. Biol. 77 2001 271 279
-
(2001)
J. Steroid Biochem. Mol. Biol.
, vol.77
, pp. 271-279
-
-
Taras, T.L.1
Wurz, G.T.2
Degregorio, M.W.3
-
27
-
-
84655163386
-
Ospemifene and 4-hydroxyospemifene effectively prevent and treat breast cancer in the MTag.Tg transgenic mouse model
-
R.A. Burich, N.R. Mehta, G.T. Wurz, J.L. McCall, B.E. Greenberg, K.E. Bell, S.M. Griffey, and M.W. DeGregorio Ospemifene and 4-hydroxyospemifene effectively prevent and treat breast cancer in the MTag.Tg transgenic mouse model Menopause 19 2012 96 103
-
(2012)
Menopause
, vol.19
, pp. 96-103
-
-
Burich, R.A.1
Mehta, N.R.2
Wurz, G.T.3
McCall, J.L.4
Greenberg, B.E.5
Bell, K.E.6
Griffey, S.M.7
Degregorio, M.W.8
-
28
-
-
33745603721
-
Effects of ospemifene and raloxifene on biochemical markers of bone turnover in postmenopausal women
-
J. Komi, K.S. Lankinen, M. DeGregorio, J. Heikkinen, S. Saarikoski, M. Tuppurainen, K. Halonen, R. Lammintausta, K. Vaananen, O. Ylikorkala, and R. Erkkola Effects of ospemifene and raloxifene on biochemical markers of bone turnover in postmenopausal women J. Bone Miner. Metab. 24 2006 314 318
-
(2006)
J. Bone Miner. Metab.
, vol.24
, pp. 314-318
-
-
Komi, J.1
Lankinen, K.S.2
Degregorio, M.3
Heikkinen, J.4
Saarikoski, S.5
Tuppurainen, M.6
Halonen, K.7
Lammintausta, R.8
Vaananen, K.9
Ylikorkala, O.10
Erkkola, R.11
-
29
-
-
41849138667
-
Effects of bazedoxifene on BMD and bone turnover in postmenopausal women: 2-yr results of a randomized, double-blind, placebo-, and active-controlled study
-
P.D. Miller, A.A. Chines, C. Christiansen, H.C. Hoeck, D.L. Kendler, E.M. Lewiecki, G. Woodson, A.B. Levine, G. Constantine, and P.D. Delmas Effects of bazedoxifene on BMD and bone turnover in postmenopausal women: 2-yr results of a randomized, double-blind, placebo-, and active-controlled study J. Bone Miner. Res. 23 2008 525 535
-
(2008)
J. Bone Miner. Res.
, vol.23
, pp. 525-535
-
-
Miller, P.D.1
Chines, A.A.2
Christiansen, C.3
Hoeck, H.C.4
Kendler, D.L.5
Lewiecki, E.M.6
Woodson, G.7
Levine, A.B.8
Constantine, G.9
Delmas, P.D.10
-
30
-
-
84857483773
-
Bazedoxifene: The evolving role of third-generation selective estrogen-receptor modulators in the management of postmenopausal osteoporosis
-
B.S. Komm, and A.A. Chines Bazedoxifene: the evolving role of third-generation selective estrogen-receptor modulators in the management of postmenopausal osteoporosis Ther. Adv. Musculoskelet. Dis. 4 2012 21 34
-
(2012)
Ther. Adv. Musculoskelet. Dis.
, vol.4
, pp. 21-34
-
-
Komm, B.S.1
Chines, A.A.2
-
31
-
-
77956652851
-
SERMs: Progress and future perspectives
-
J.H. Pickar, T. MacNeil, and K. Ohleth SERMs: progress and future perspectives Maturitas 67 2010 129 138
-
(2010)
Maturitas
, vol.67
, pp. 129-138
-
-
Pickar, J.H.1
Macneil, T.2
Ohleth, K.3
-
32
-
-
0033870635
-
Prevention and treatment of osteoporosis in women with breast cancer
-
B.A. Mincey, T.J. Moraghan, and E.A. Perez Prevention and treatment of osteoporosis in women with breast cancer Mayo Clin. Proc. 75 2000 821 829
-
(2000)
Mayo Clin. Proc.
, vol.75
, pp. 821-829
-
-
Mincey, B.A.1
Moraghan, T.J.2
Perez, E.A.3
-
33
-
-
0036133366
-
Bone turnover matters: The raloxifene treatment paradox of dramatic decreases in vertebral fractures without commensurate increases in bone density
-
B.L. Riggs, and L.J. Melton III Bone turnover matters: the raloxifene treatment paradox of dramatic decreases in vertebral fractures without commensurate increases in bone density J. Bone Miner. Res. 17 2002 11 14
-
(2002)
J. Bone Miner. Res.
, vol.17
, pp. 11-14
-
-
Riggs, B.L.1
Melton III, L.J.2
-
34
-
-
0344233260
-
Meta-analysis of vascular and neoplastic events associated with tamoxifen
-
R.S. Braithwaite, R.T. Chlebowski, J. Lau, S. George, R. Hess, and N.F. Col Meta-analysis of vascular and neoplastic events associated with tamoxifen J. Gen. Intern. Med. 18 2003 937 947
-
(2003)
J. Gen. Intern. Med.
, vol.18
, pp. 937-947
-
-
Braithwaite, R.S.1
Chlebowski, R.T.2
Lau, J.3
George, S.4
Hess, R.5
Col, N.F.6
-
35
-
-
84877348066
-
Long-term cardiac and vascular disease outcomes following adjuvant tamoxifen therapy: Current understanding of impact on physiology and overall survival
-
A.A. Onitilo, P. Kar, J.M. Engel, and I. Glurich Long-term cardiac and vascular disease outcomes following adjuvant tamoxifen therapy: current understanding of impact on physiology and overall survival Minerva Med. 104 2013 141 153
-
(2013)
Minerva Med.
, vol.104
, pp. 141-153
-
-
Onitilo, A.A.1
Kar, P.2
Engel, J.M.3
Glurich, I.4
-
36
-
-
0037016060
-
Influence of tamoxifen on carotid intima-media thickness in postmenopausal women
-
T. Simon, P. Boutouyrie, J.M. Simon, B. Laloux, C. Tournigand, A.I. Tropeano, S. Laurent, and P. Jaillon Influence of tamoxifen on carotid intima-media thickness in postmenopausal women Circulation 106 2002 2925 2929
-
(2002)
Circulation
, vol.106
, pp. 2925-2929
-
-
Simon, T.1
Boutouyrie, P.2
Simon, J.M.3
Laloux, B.4
Tournigand, C.5
Tropeano, A.I.6
Laurent, S.7
Jaillon, P.8
-
37
-
-
61849168916
-
Effects of the selective estrogen receptor modulator raloxifene on coronary outcomes in the Raloxifene Use for the Heart trial: Results of subgroup analyses by age and other factors
-
P. Collins, L. Mosca, M.J. Geiger, D. Grady, M. Kornitzer, M.G. mewou-Atisso, M.B. Effron, S.A. Dowsett, E. Barrett-Connor, and N.K. Wenger Effects of the selective estrogen receptor modulator raloxifene on coronary outcomes in the Raloxifene Use for The Heart trial: results of subgroup analyses by age and other factors Circulation 119 2009 922 930
-
(2009)
Circulation
, vol.119
, pp. 922-930
-
-
Collins, P.1
Mosca, L.2
Geiger, M.J.3
Grady, D.4
Kornitzer, M.5
Mewou-Atisso, M.G.6
Effron, M.B.7
Dowsett, S.A.8
Barrett-Connor, E.9
Wenger, N.K.10
-
38
-
-
33745876266
-
Effects of raloxifene on cardiovascular events and breast cancer in postmenopausal women
-
E. Barrett-Connor, L. Mosca, P. Collins, M.J. Geiger, D. Grady, M. Kornitzer, M.A. McNabb, and N.K. Wenger Effects of raloxifene on cardiovascular events and breast cancer in postmenopausal women N. Engl. J. Med. 355 2006 125 137
-
(2006)
N. Engl. J. Med.
, vol.355
, pp. 125-137
-
-
Barrett-Connor, E.1
Mosca, L.2
Collins, P.3
Geiger, M.J.4
Grady, D.5
Kornitzer, M.6
McNabb, M.A.7
Wenger, N.K.8
-
39
-
-
78149283316
-
Lasofoxifene and cardiovascular events in postmenopausal women with osteoporosis: Five-year results from the Postmenopausal Evaluation and Risk Reduction with Lasofoxifene (PEARL) trial
-
K. Ensrud, A. LaCroix, J.R. Thompson, D.D. Thompson, R. Eastell, D.M. Reid, S. Vukicevic, J. Cauley, E. Barrett-Connor, R. Armstrong, F. Welty, and S. Cummings Lasofoxifene and cardiovascular events in postmenopausal women with osteoporosis: five-year results from the Postmenopausal Evaluation and Risk Reduction with Lasofoxifene (PEARL) trial Circulation 122 2010 1716 1724
-
(2010)
Circulation
, vol.122
, pp. 1716-1724
-
-
Ensrud, K.1
Lacroix, A.2
Thompson, J.R.3
Thompson, D.D.4
Eastell, R.5
Reid, D.M.6
Vukicevic, S.7
Cauley, J.8
Barrett-Connor, E.9
Armstrong, R.10
Welty, F.11
Cummings, S.12
-
40
-
-
85028098042
-
One-year long-term safety extension study of ospemifene for the treatment of vulvar and vaginal atrophy in postmenopausal women with a uterus
-
Ospemifene Study Group
-
J.A. Simon, V.H. Lin, C. Radovich, G.A. Bachmann Ospemifene Study Group One-year long-term safety extension study of ospemifene for the treatment of vulvar and vaginal atrophy in postmenopausal women with a uterus Menopause 20 2012 418 427
-
(2012)
Menopause
, vol.20
, pp. 418-427
-
-
Simon, J.A.1
Lin, V.H.2
Radovich, C.3
Bachmann, G.A.4
-
41
-
-
73949097340
-
Clinical issues regarding cardiovascular disease and selective estrogen receptor modulators in postmenopausal women
-
T.J. De Villiers Clinical issues regarding cardiovascular disease and selective estrogen receptor modulators in postmenopausal women Climacteric 12 Suppl. 1 2009 108 111
-
(2009)
Climacteric
, vol.12
, Issue.SUPPL. 1
, pp. 108-111
-
-
De Villiers, T.J.1
-
42
-
-
13444294235
-
Effect of tamoxifen on venous thromboembolic events in a breast cancer prevention trial
-
A. Decensi, P. Maisonneuve, N. Rotmensz, D. Bettega, A. Costa, V. Sacchini, A. Salvioni, R. Travaglini, P. Oliviero, G. D'Aiuto, M. Gulisano, G. Gucciardo, M.R. del Turco, M.A. Pizzichetta, S. Conforti, B. Bonanni, P. Boyle, and U. Veronesi Effect of tamoxifen on venous thromboembolic events in a breast cancer prevention trial Circulation 111 2005 650 656
-
(2005)
Circulation
, vol.111
, pp. 650-656
-
-
Decensi, A.1
Maisonneuve, P.2
Rotmensz, N.3
Bettega, D.4
Costa, A.5
Sacchini, V.6
Salvioni, A.7
Travaglini, R.8
Oliviero, P.9
D'Aiuto, G.10
Gulisano, M.11
Gucciardo, G.12
Del Turco, M.R.13
Pizzichetta, M.A.14
Conforti, S.15
Bonanni, B.16
Boyle, P.17
Veronesi, U.18
-
43
-
-
56549092475
-
Efficacy of bazedoxifene in reducing new vertebral fracture risk in postmenopausal women with osteoporosis: Results from a 3-year, randomized, placebo- and active-controlled clinical trial
-
S.L. Silverman, C. Christiansen, H.K. Genant, S. Vukicevic, J.R. Zanchetta, T.J. De Villiers, G.D. Constantine, and A.A. Chines Efficacy of bazedoxifene in reducing new vertebral fracture risk in postmenopausal women with osteoporosis: results from a 3-year, randomized, placebo- and active-controlled clinical trial J. Bone Miner. Res. 23 2008 1923 1934
-
(2008)
J. Bone Miner. Res.
, vol.23
, pp. 1923-1934
-
-
Silverman, S.L.1
Christiansen, C.2
Genant, H.K.3
Vukicevic, S.4
Zanchetta, J.R.5
De Villiers, T.J.6
Constantine, G.D.7
Chines, A.A.8
-
44
-
-
77952270259
-
Ospemifene effectively treats vulvovaginal atrophy in postmenopausal women: Results from a pivotal phase 3 study
-
G.A. Bachmann, and J.O. Komi Ospemifene effectively treats vulvovaginal atrophy in postmenopausal women: results from a pivotal phase 3 study Menopause 17 2010 480 486
-
(2010)
Menopause
, vol.17
, pp. 480-486
-
-
Bachmann, G.A.1
Komi, J.O.2
-
46
-
-
27544454121
-
Selective estrogen receptor modulators (SERMs) for the brain: Current status and remaining challenges for developing NeuroSERMs
-
L. Zhao, K. O'Neill, and B.R. Diaz Selective estrogen receptor modulators (SERMs) for the brain: current status and remaining challenges for developing NeuroSERMs Brain Res. Brain Res. Rev. 49 2005 472 493
-
(2005)
Brain Res. Brain Res. Rev.
, vol.49
, pp. 472-493
-
-
Zhao, L.1
O'Neill, K.2
Diaz, B.R.3
-
48
-
-
79551718178
-
Selective estrogen receptor modulators as brain therapeutic agents
-
M.A. Arevalo, M. Santos-Galindo, N. Lagunas, I. Azcoitia, and L.M. Garcia-Segura Selective estrogen receptor modulators as brain therapeutic agents J. Mol. Endocrinol. 46 2011 R1 R9
-
(2011)
J. Mol. Endocrinol.
, vol.46
-
-
Arevalo, M.A.1
Santos-Galindo, M.2
Lagunas, N.3
Azcoitia, I.4
Garcia-Segura, L.M.5
-
49
-
-
84879172530
-
Ospemifene, a novel selective estrogen receptor modulator for treating dyspareunia associated with postmenopausal vulvar and vaginal atrophy
-
D.J. Portman, G.A. Bachmann, and J.A. Simon Ospemifene, a novel selective estrogen receptor modulator for treating dyspareunia associated with postmenopausal vulvar and vaginal atrophy Menopause 20 2013 623 630
-
(2013)
Menopause
, vol.20
, pp. 623-630
-
-
Portman, D.J.1
Bachmann, G.A.2
Simon, J.A.3
-
50
-
-
68949097428
-
Lasofoxifene, a new selective estrogen receptor modulator for the treatment of osteoporosis and vaginal atrophy
-
L. Gennari Lasofoxifene, a new selective estrogen receptor modulator for the treatment of osteoporosis and vaginal atrophy Expert Opin. Pharmacother. 10 2009 2209 2220
-
(2009)
Expert Opin. Pharmacother.
, vol.10
, pp. 2209-2220
-
-
Gennari, L.1
-
51
-
-
0034650419
-
Characterization of hot flashes reported by healthy postmenopausal women receiving raloxifene or placebo during osteoporosis prevention trials
-
F.J. Cohen, and Y. Lu Characterization of hot flashes reported by healthy postmenopausal women receiving raloxifene or placebo during osteoporosis prevention trials Maturitas 34 2000 65 73
-
(2000)
Maturitas
, vol.34
, pp. 65-73
-
-
Cohen, F.J.1
Lu, Y.2
-
52
-
-
85027926708
-
Selective estrogen receptor modulators and their effects on hot flashes: A dilemma
-
C. Bouchard Selective estrogen receptor modulators and their effects on hot flashes: a dilemma Menopause 18 2011 477 479
-
(2011)
Menopause
, vol.18
, pp. 477-479
-
-
Bouchard, C.1
-
53
-
-
63849087262
-
RAD-1901, a novel SERM, has efficacy in an animal model of vasomotor symptoms
-
Toronto, Canada
-
D.G. Hattersley, S. Paquin, and S. Ho RAD-1901, a novel SERM, has efficacy in an animal model of vasomotor symptoms Presented at the 89th Annual Meeting of the Endocrine Society, June 2-5 Toronto, Canada 2007
-
(2007)
Presented at the 89th Annual Meeting of the Endocrine Society, June 2-5
-
-
Hattersley, D.G.1
Paquin, S.2
Ho, S.3
-
54
-
-
34447266932
-
The effects of combined raloxifene and oral estrogen on vasomotor symptoms and endometrial safety
-
D.W. Stovall, W. Utian, M. Gass, Y. Qu, D. Muram, M. Wong, and L. Plouffe Jr. The effects of combined raloxifene and oral estrogen on vasomotor symptoms and endometrial safety Menopause 14 2007 510 517
-
(2007)
Menopause
, vol.14
, pp. 510-517
-
-
Stovall, D.W.1
Utian, W.2
Gass, M.3
Qu, Y.4
Muram, D.5
Wong, M.6
Plouffe, Jr.L.7
-
55
-
-
68949108335
-
Pharmacology and clinical applications of selective estrogen receptor modulators
-
A. Nath, and R. Sitruk-Ware Pharmacology and clinical applications of selective estrogen receptor modulators Climacteric 12 2009 188 205
-
(2009)
Climacteric
, vol.12
, pp. 188-205
-
-
Nath, A.1
Sitruk-Ware, R.2
-
57
-
-
27944492407
-
Tamoxifen for the prevention of breast cancer: Current status of the National Surgical Adjuvant Breast and Bowel Project P-1 study
-
B. Fisher, J.P. Costantino, D.L. Wickerham, R.S. Cecchini, W.M. Cronin, A. Robidoux, T.B. Bevers, M.T. Kavanah, J.N. Atkins, R.G. Margolese, C.D. Runowicz, J.M. James, L.G. Ford, and N. Wolmark Tamoxifen for the prevention of breast cancer: current status of the National Surgical Adjuvant Breast and Bowel Project P-1 study J. Natl. Cancer Inst. 97 2005 1652 1662
-
(2005)
J. Natl. Cancer Inst.
, vol.97
, pp. 1652-1662
-
-
Fisher, B.1
Costantino, J.P.2
Wickerham, D.L.3
Cecchini, R.S.4
Cronin, W.M.5
Robidoux, A.6
Bevers, T.B.7
Kavanah, M.T.8
Atkins, J.N.9
Margolese, R.G.10
Runowicz, C.D.11
James, J.M.12
Ford, L.G.13
Wolmark, N.14
-
58
-
-
0032569831
-
Tamoxifen in the treatment of breast cancer
-
C.K. Osborne Tamoxifen in the treatment of breast cancer N. Engl. J. Med. 339 1998 1609 1618
-
(1998)
N. Engl. J. Med.
, vol.339
, pp. 1609-1618
-
-
Osborne, C.K.1
-
59
-
-
85203363507
-
Relevance of breast cancer hormone receptors and other factors to the efficacy of adjuvant tamoxifen: Patient-level meta-analysis of randomised trials
-
Early Breast Cancer Trialists' Collaborative Group (EBCTCG)
-
C. Davies, J. Godwin, R. Gray, M. Clarke, D. Cutter, S. Darby, P. McGale, H.C. Pan, C. Taylor, Y.C. Wang, M. Dowsett, J. Ingle, R. Peto Early Breast Cancer Trialists' Collaborative Group (EBCTCG) Relevance of breast cancer hormone receptors and other factors to the efficacy of adjuvant tamoxifen: patient-level meta-analysis of randomised trials Lancet 378 2011 771 784
-
(2011)
Lancet
, vol.378
, pp. 771-784
-
-
Davies, C.1
Godwin, J.2
Gray, R.3
Clarke, M.4
Cutter, D.5
Darby, S.6
McGale, P.7
Pan, H.C.8
Taylor, C.9
Wang, Y.C.10
Dowsett, M.11
Ingle, J.12
Peto, R.13
-
60
-
-
0037464769
-
Overview of the main outcomes in breast-cancer prevention trials
-
J. Cuzick, T. Powles, U. Veronesi, J. Forbes, R. Edwards, S. Ashley, and P. Boyle Overview of the main outcomes in breast-cancer prevention trials Lancet 361 2003 296 300
-
(2003)
Lancet
, vol.361
, pp. 296-300
-
-
Cuzick, J.1
Powles, T.2
Veronesi, U.3
Forbes, J.4
Edwards, R.5
Ashley, S.6
Boyle, P.7
-
61
-
-
84874745627
-
Long-term effects of continuing adjuvant tamoxifen to 10 years versus stopping at 5 years after diagnosis of oestrogen receptor-positive breast cancer: ATLAS, a randomised trial
-
C. Davies, H. Pan, J. Godwin, R. Gray, R. Arriagada, V. Raina, M. Abraham, V.H. Alencar, A. Badran, X. Bonfill, J. Bradbury, M. Clarke, R. Collins, S.R. Davis, A. Delmestri, J.F. Forbes, P. Haddad, M.F. Hou, M. Inbar, H. Khaled, J. Kielanowska, W.H. Kwan, B.S. Mathew, I. Mittra, B. Muller, A. Nicolucci, O. Peralta, F. Pernas, L. Petruzelka, T. Pienkowski, R. Radhika, B. Rajan, M.T. Rubach, S. Tort, G. Urrutia, M. Valentini, Y. Wang, and R. Peto Long-term effects of continuing adjuvant tamoxifen to 10 years versus stopping at 5 years after diagnosis of oestrogen receptor-positive breast cancer: ATLAS, a randomised trial Lancet 381 2013 805 816
-
(2013)
Lancet
, vol.381
, pp. 805-816
-
-
Davies, C.1
Pan, H.2
Godwin, J.3
Gray, R.4
Arriagada, R.5
Raina, V.6
Abraham, M.7
Alencar, V.H.8
Badran, A.9
Bonfill, X.10
Bradbury, J.11
Clarke, M.12
Collins, R.13
Davis, S.R.14
Delmestri, A.15
Forbes, J.F.16
Haddad, P.17
Hou, M.F.18
Inbar, M.19
Khaled, H.20
Kielanowska, J.21
Kwan, W.H.22
Mathew, B.S.23
Mittra, I.24
Muller, B.25
Nicolucci, A.26
Peralta, O.27
Pernas, F.28
Petruzelka, L.29
Pienkowski, T.30
Radhika, R.31
Rajan, B.32
Rubach, M.T.33
Tort, S.34
Urrutia, G.35
Valentini, M.36
Wang, Y.37
Peto, R.38
more..
-
62
-
-
0030070093
-
Effect of tamoxifen on bone mineral density measured by dual-energy X-ray absorptiometry in healthy premenopausal and postmenopausal women
-
T.J. Powles, T. Hickish, J.A. Kanis, A. Tidy, and S. Ashley Effect of tamoxifen on bone mineral density measured by dual-energy X-ray absorptiometry in healthy premenopausal and postmenopausal women J. Clin. Oncol. 14 1996 78 84
-
(1996)
J. Clin. Oncol.
, vol.14
, pp. 78-84
-
-
Powles, T.J.1
Hickish, T.2
Kanis, J.A.3
Tidy, A.4
Ashley, S.5
-
63
-
-
0026585852
-
Effects of tamoxifen on bone mineral density in postmenopausal women with breast cancer
-
R.R. Love, R.B. Mazess, H.S. Barden, S. Epstein, P.A. Newcomb, V.C. Jordan, P.P. Carbone, and D.L. DeMets Effects of tamoxifen on bone mineral density in postmenopausal women with breast cancer N. Engl. J. Med. 326 1992 852 856
-
(1992)
N. Engl. J. Med.
, vol.326
, pp. 852-856
-
-
Love, R.R.1
Mazess, R.B.2
Barden, H.S.3
Epstein, S.4
Newcomb, P.A.5
Jordan, V.C.6
Carbone, P.P.7
Demets, D.L.8
-
64
-
-
33644842287
-
Tamoxifen treatment after adjuvant chemotherapy has opposite effects on bone mineral density in premenopausal patients depending on menstrual status
-
L. Vehmanen, I. Elomaa, C. Blomqvist, and T. Saarto Tamoxifen treatment after adjuvant chemotherapy has opposite effects on bone mineral density in premenopausal patients depending on menstrual status J. Clin. Oncol. 24 2006 675 680
-
(2006)
J. Clin. Oncol.
, vol.24
, pp. 675-680
-
-
Vehmanen, L.1
Elomaa, I.2
Blomqvist, C.3
Saarto, T.4
-
65
-
-
4644297698
-
Bone mineral density among premenopausal women with early breast cancer in a randomized trial of adjuvant endocrine therapy
-
A. Sverrisdottir, T. Fornander, H. Jacobsson, S.E. von, and L.E. Rutqvist Bone mineral density among premenopausal women with early breast cancer in a randomized trial of adjuvant endocrine therapy J. Clin. Oncol. 22 2004 3694 3699
-
(2004)
J. Clin. Oncol.
, vol.22
, pp. 3694-3699
-
-
Sverrisdottir, A.1
Fornander, T.2
Jacobsson, H.3
Von, S.E.4
Rutqvist, L.E.5
-
66
-
-
0028208456
-
Endometrial cancer in tamoxifen-treated breast cancer patients: Findings from the National Surgical Adjuvant Breast and Bowel Project (NSABP) B-14
-
B. Fisher, J.P. Costantino, C.K. Redmond, E.R. Fisher, D.L. Wickerham, and W.M. Cronin Endometrial cancer in tamoxifen-treated breast cancer patients: findings from the National Surgical Adjuvant Breast and Bowel Project (NSABP) B-14 J. Natl. Cancer Inst. 86 1994 527 537
-
(1994)
J. Natl. Cancer Inst.
, vol.86
, pp. 527-537
-
-
Fisher, B.1
Costantino, J.P.2
Redmond, C.K.3
Fisher, E.R.4
Wickerham, D.L.5
Cronin, W.M.6
-
68
-
-
34250874481
-
Outcomes in patients with primary breast cancer and a subsequent diagnosis of endometrial cancer: Comparison of cohorts treated with and without tamoxifen
-
M. Saadat, P.T. Truong, H.A. Kader, C.H. Speers, E. Berthelet, E. McMurtrie, and I.A. Olivotto Outcomes in patients with primary breast cancer and a subsequent diagnosis of endometrial cancer: comparison of cohorts treated with and without tamoxifen Cancer 110 2007 31 37
-
(2007)
Cancer
, vol.110
, pp. 31-37
-
-
Saadat, M.1
Truong, P.T.2
Kader, H.A.3
Speers, C.H.4
Berthelet, E.5
McMurtrie, E.6
Olivotto, I.A.7
-
69
-
-
57649108536
-
Relationship between tamoxifen use and high risk endometrial cancer histologic types
-
A.E. Bland, B. Calingaert, A.A. Secord, P.S. Lee, F.A. Valea, A. Berchuck, J.T. Soper, and L. Havrilesky Relationship between tamoxifen use and high risk endometrial cancer histologic types Gynecol. Oncol. 112 2009 150 154
-
(2009)
Gynecol. Oncol.
, vol.112
, pp. 150-154
-
-
Bland, A.E.1
Calingaert, B.2
Secord, A.A.3
Lee, P.S.4
Valea, F.A.5
Berchuck, A.6
Soper, J.T.7
Havrilesky, L.8
-
70
-
-
52949137964
-
Prognosis of uterine corpus cancer after tamoxifen treatment for breast cancer
-
W.E. Hoogendoorn, H. Hollema, H.H. van Boven, E. Bergman, G. de Leeuw-Mantel, I. Platteel, R. Fles, P.M. Nederlof, M.J. Mourits, and F.E. Van Leeuwen Prognosis of uterine corpus cancer after tamoxifen treatment for breast cancer Breast Cancer Res. Treat. 112 2008 99 108
-
(2008)
Breast Cancer Res. Treat.
, vol.112
, pp. 99-108
-
-
Hoogendoorn, W.E.1
Hollema, H.2
Van Boven, H.H.3
Bergman, E.4
De Leeuw-Mantel, G.5
Platteel, I.6
Fles, R.7
Nederlof, P.M.8
Mourits, M.J.9
Van Leeuwen, F.E.10
-
71
-
-
14544270313
-
Tamoxifen treatment for breast cancer and risk of endometrial cancer: A case-control study
-
A.J. Swerdlow, and M.E. Jones Tamoxifen treatment for breast cancer and risk of endometrial cancer: a case-control study J. Natl. Cancer Inst. 97 2005 375 384
-
(2005)
J. Natl. Cancer Inst.
, vol.97
, pp. 375-384
-
-
Swerdlow, A.J.1
Jones, M.E.2
-
72
-
-
3242773754
-
The risk of venous thromboembolic disease associated with adjuvant hormone therapy for breast carcinoma: A systematic review
-
S.R. Deitcher, and M.P. Gomes The risk of venous thromboembolic disease associated with adjuvant hormone therapy for breast carcinoma: a systematic review Cancer 101 2004 439 449
-
(2004)
Cancer
, vol.101
, pp. 439-449
-
-
Deitcher, S.R.1
Gomes, M.P.2
-
73
-
-
33746310357
-
Toremifene: An evaluation of its safety profile
-
H.A. Harvey, M. Kimura, and A. Hajba Toremifene: an evaluation of its safety profile Breast 15 2006 142 157
-
(2006)
Breast
, vol.15
, pp. 142-157
-
-
Harvey, H.A.1
Kimura, M.2
Hajba, A.3
-
74
-
-
9844266794
-
A phase III comparison of two toremifene doses to tamoxifen in postmenopausal women with advanced breast cancer. Eastern European Study Group
-
M. Gershanovich, A. Garin, D. Baltina, A. Kurvet, L. Kangas, and J. Ellmen A phase III comparison of two toremifene doses to tamoxifen in postmenopausal women with advanced breast cancer. Eastern European Study Group Breast Cancer Res. Treat. 45 1997 251 262
-
(1997)
Breast Cancer Res. Treat.
, vol.45
, pp. 251-262
-
-
Gershanovich, M.1
Garin, A.2
Baltina, D.3
Kurvet, A.4
Kangas, L.5
Ellmen, J.6
-
75
-
-
0029084658
-
Randomized comparison of tamoxifen and two separate doses of toremifene in postmenopausal patients with metastatic breast cancer
-
D.F. Hayes, J.A. Van Zyl, A. Hacking, L. Goedhals, W.R. Bezwoda, J.A. Mailliard, S.E. Jones, C.L. Vogel, R.F. Berris, and I. Shemano Randomized comparison of tamoxifen and two separate doses of toremifene in postmenopausal patients with metastatic breast cancer J. Clin. Oncol. 13 1995 2556 2566
-
(1995)
J. Clin. Oncol.
, vol.13
, pp. 2556-2566
-
-
Hayes, D.F.1
Van Zyl, J.A.2
Hacking, A.3
Goedhals, L.4
Bezwoda, W.R.5
Mailliard, J.A.6
Jones, S.E.7
Vogel, C.L.8
Berris, R.F.9
Shemano, I.10
-
76
-
-
2642657654
-
Comparison of toremifene and tamoxifen in post-menopausal patients with advanced breast cancer: A randomized double-blind, the 'nordic' phase III study
-
S. Pyrhonen, R. Valavaara, H. Modig, M. Pawlicki, T. Pienkowski, S. Gundersen, J. Bauer, G. Westman, S. Lundgren, G. Blanco, O. Mella, I. Nilsson, T. Hietanen, I. Hindy, J. Vuorinen, and A. Hajba Comparison of toremifene and tamoxifen in post-menopausal patients with advanced breast cancer: a randomized double-blind, the 'nordic' phase III study Br. J. Cancer 76 1997 270 277
-
(1997)
Br. J. Cancer
, vol.76
, pp. 270-277
-
-
Pyrhonen, S.1
Valavaara, R.2
Modig, H.3
Pawlicki, M.4
Pienkowski, T.5
Gundersen, S.6
Bauer, J.7
Westman, G.8
Lundgren, S.9
Blanco, G.10
Mella, O.11
Nilsson, I.12
Hietanen, T.13
Hindy, I.14
Vuorinen, J.15
Hajba, A.16
-
77
-
-
84899957713
-
-
US Preventative Services Task Force Available at: (accessed 25.11.13)
-
Medications for Risk Reduction of Primary Breast Cancer in Women 2013 US Preventative Services Task Force Available at: www. uspreventiveservicestaskforce.org/uspstf/uspsbrpv.htm (accessed 25.11.13)
-
(2013)
Medications for Risk Reduction of Primary Breast Cancer in Women
-
-
-
78
-
-
0033581212
-
Reduction of vertebral fracture risk in postmenopausal women with osteoporosis treated with raloxifene: Results from a 3-year randomized clinical trial. Multiple Outcomes of Raloxifene Evaluation (MORE) Investigators
-
B. Ettinger, D.M. Black, B.H. Mitlak, R.K. Knickerbocker, T. Nickelsen, H.K. Genant, C. Christiansen, P.D. Delmas, J.R. Zanchetta, J. Stakkestad, C.C. Gluer, K. Krueger, F.J. Cohen, S. Eckert, K.E. Ensrud, L.V. Avioli, P. Lips, and S.R. Cummings Reduction of vertebral fracture risk in postmenopausal women with osteoporosis treated with raloxifene: results from a 3-year randomized clinical trial. Multiple Outcomes of Raloxifene Evaluation (MORE) Investigators JAMA 282 1999 637 645
-
(1999)
JAMA
, vol.282
, pp. 637-645
-
-
Ettinger, B.1
Black, D.M.2
Mitlak, B.H.3
Knickerbocker, R.K.4
Nickelsen, T.5
Genant, H.K.6
Christiansen, C.7
Delmas, P.D.8
Zanchetta, J.R.9
Stakkestad, J.10
Gluer, C.C.11
Krueger, K.12
Cohen, F.J.13
Eckert, S.14
Ensrud, K.E.15
Avioli, L.V.16
Lips, P.17
Cummings, S.R.18
-
79
-
-
0037182042
-
Early effects of raloxifene on clinical vertebral fractures at 12 months in postmenopausal women with osteoporosis
-
M. Maricic, J.D. Adachi, S. Sarkar, W. Wu, M. Wong, and K.D. Harper Early effects of raloxifene on clinical vertebral fractures at 12 months in postmenopausal women with osteoporosis Arch. Intern. Med. 162 2002 1140 1143
-
(2002)
Arch. Intern. Med.
, vol.162
, pp. 1140-1143
-
-
Maricic, M.1
Adachi, J.D.2
Sarkar, S.3
Wu, W.4
Wong, M.5
Harper, K.D.6
-
80
-
-
0041762479
-
Effect of raloxifene on the risk of new vertebral fracture in postmenopausal women with osteopenia or osteoporosis: A reanalysis of the Multiple Outcomes of Raloxifene Evaluation trial
-
J.A. Kanis, O. Johnell, D.M. Black, R.W. Downs Jr., S. Sarkar, T. Fuerst, R.J. Secrest, and I. Pavo Effect of raloxifene on the risk of new vertebral fracture in postmenopausal women with osteopenia or osteoporosis: a reanalysis of the Multiple Outcomes of Raloxifene Evaluation trial Bone 33 2003 293 300
-
(2003)
Bone
, vol.33
, pp. 293-300
-
-
Kanis, J.A.1
Johnell, O.2
Black, D.M.3
Downs, Jr.R.W.4
Sarkar, S.5
Fuerst, T.6
Secrest, R.J.7
Pavo, I.8
-
81
-
-
0141750678
-
Severity of prevalent vertebral fractures and the risk of subsequent vertebral and nonvertebral fractures: Results from the MORE trial
-
P.D. Delmas, H.K. Genant, G.G. Crans, J.L. Stock, M. Wong, E. Siris, and J.D. Adachi Severity of prevalent vertebral fractures and the risk of subsequent vertebral and nonvertebral fractures: results from the MORE trial Bone 33 2003 522 532
-
(2003)
Bone
, vol.33
, pp. 522-532
-
-
Delmas, P.D.1
Genant, H.K.2
Crans, G.G.3
Stock, J.L.4
Wong, M.5
Siris, E.6
Adachi, J.D.7
-
82
-
-
84875147170
-
Fractures in women treated with raloxifene or alendronate: A retrospective database analysis
-
S.A. Foster, N. Shi, S. Curkendall, J. Stock, B.C. Chu, R. Burge, D.R. Diakun, and J.H. Krege Fractures in women treated with raloxifene or alendronate: a retrospective database analysis BMC Womens Health 13 2013 15
-
(2013)
BMC Womens Health
, vol.13
, pp. 15
-
-
Foster, S.A.1
Shi, N.2
Curkendall, S.3
Stock, J.4
Chu, B.C.5
Burge, R.6
Diakun, D.R.7
Krege, J.H.8
-
83
-
-
51649084822
-
Impact of raloxifene or tamoxifen use on endometrial cancer risk: A population-based case-control study
-
A. DeMichele, A.B. Troxel, J.A. Berlin, A.L. Weber, G.R. Bunin, E. Turzo, R. Schinnar, D. Burgh, M. Berlin, S.C. Rubin, T.R. Rebbeck, and B.L. Strom Impact of raloxifene or tamoxifen use on endometrial cancer risk: a population-based case-control study J. Clin. Oncol. 26 2008 4151 4159
-
(2008)
J. Clin. Oncol.
, vol.26
, pp. 4151-4159
-
-
Demichele, A.1
Troxel, A.B.2
Berlin, J.A.3
Weber, A.L.4
Bunin, G.R.5
Turzo, E.6
Schinnar, R.7
Burgh, D.8
Berlin, M.9
Rubin, S.C.10
Rebbeck, T.R.11
Strom, B.L.12
-
84
-
-
0037308677
-
Effect of raloxifene on the response to conjugated estrogen vaginal cream or nonhormonal moisturizers in postmenopausal vaginal atrophy
-
A. Parsons, D. Merritt, A. Rosen, H. Heath III, S. Siddhanti, and L. Plouffe Jr. Effect of raloxifene on the response to conjugated estrogen vaginal cream or nonhormonal moisturizers in postmenopausal vaginal atrophy Obstet. Gynecol. 101 2003 346 352
-
(2003)
Obstet. Gynecol.
, vol.101
, pp. 346-352
-
-
Parsons, A.1
Merritt, D.2
Rosen, A.3
Heath III, H.4
Siddhanti, S.5
Plouffe, Jr.L.6
-
85
-
-
0038182702
-
Influence of raloxifene on the efficacy of an estradiol-releasing ring for treating vaginal atrophy in postmenopausal women
-
J.V. Pinkerton, J.L. Shifren, V.J. La, A. Rosen, M. Roesinger, and S. Siddhanti Influence of raloxifene on the efficacy of an estradiol-releasing ring for treating vaginal atrophy in postmenopausal women Menopause 10 2003 45 52
-
(2003)
Menopause
, vol.10
, pp. 45-52
-
-
Pinkerton, J.V.1
Shifren, J.L.2
La, V.J.3
Rosen, A.4
Roesinger, M.5
Siddhanti, S.6
-
86
-
-
20144388972
-
Effects of ospemifene and raloxifene on hormonal status, lipids, genital tract, and tolerability in postmenopausal women
-
J. Komi, K.S. Lankinen, P. Harkonen, M.W. DeGregorio, S. Voipio, S. Kivinen, R. Tuimala, T. Vihtamaki, K. Vihko, O. Ylikorkala, and R. Erkkola Effects of ospemifene and raloxifene on hormonal status, lipids, genital tract, and tolerability in postmenopausal women Menopause 12 2005 202 209
-
(2005)
Menopause
, vol.12
, pp. 202-209
-
-
Komi, J.1
Lankinen, K.S.2
Harkonen, P.3
Degregorio, M.W.4
Voipio, S.5
Kivinen, S.6
Tuimala, R.7
Vihtamaki, T.8
Vihko, K.9
Ylikorkala, O.10
Erkkola, R.11
-
87
-
-
0030664688
-
Effects of raloxifene on bone mineral density, serum cholesterol concentrations, and uterine endometrium in postmenopausal women
-
P.D. Delmas, N.H. Bjarnason, B.H. Mitlak, A.C. Ravoux, A.S. Shah, W.J. Huster, M. Draper, and C. Christiansen Effects of raloxifene on bone mineral density, serum cholesterol concentrations, and uterine endometrium in postmenopausal women N. Engl. J. Med. 337 1997 1641 1647
-
(1997)
N. Engl. J. Med.
, vol.337
, pp. 1641-1647
-
-
Delmas, P.D.1
Bjarnason, N.H.2
Mitlak, B.H.3
Ravoux, A.C.4
Shah, A.S.5
Huster, W.J.6
Draper, M.7
Christiansen, C.8
-
88
-
-
0037138787
-
Raloxifene and cardiovascular events in osteoporotic postmenopausal women: Four-year results from the MORE (Multiple Outcomes of Raloxifene Evaluation) randomized trial
-
E. Barrett-Connor, D. Grady, A. Sashegyi, P.W. Anderson, D.A. Cox, K. Hoszowski, P. Rautaharju, and K.D. Harper Raloxifene and cardiovascular events in osteoporotic postmenopausal women: four-year results from the MORE (Multiple Outcomes of Raloxifene Evaluation) randomized trial JAMA 287 2002 847 857
-
(2002)
JAMA
, vol.287
, pp. 847-857
-
-
Barrett-Connor, E.1
Grady, D.2
Sashegyi, A.3
Anderson, P.W.4
Cox, D.A.5
Hoszowski, K.6
Rautaharju, P.7
Harper, K.D.8
-
89
-
-
16844368852
-
Effect of raloxifene on prevention of dementia and cognitive impairment in older women: The Multiple Outcomes of Raloxifene Evaluation (MORE) randomized trial
-
K. Yaffe, K. Krueger, S.R. Cummings, T. Blackwell, V.W. Henderson, S. Sarkar, K. Ensrud, and D. Grady Effect of raloxifene on prevention of dementia and cognitive impairment in older women: the Multiple Outcomes of Raloxifene Evaluation (MORE) randomized trial Am. J. Psychiatry 162 2005 683 690
-
(2005)
Am. J. Psychiatry
, vol.162
, pp. 683-690
-
-
Yaffe, K.1
Krueger, K.2
Cummings, S.R.3
Blackwell, T.4
Henderson, V.W.5
Sarkar, S.6
Ensrud, K.7
Grady, D.8
-
90
-
-
77950236952
-
Relative effects of tamoxifen, raloxifene, and conjugated equine estrogens on cognition
-
M.A. Espeland, S.A. Shumaker, M. Limacher, S.R. Rapp, T.B. Bevers, D.H. Barad, L.H. Coker, S.A. Gaussoin, M.L. Stefanick, D.S. Lane, P.M. Maki, and S.M. Resnick Relative effects of tamoxifen, raloxifene, and conjugated equine estrogens on cognition J. Womens Health (Larchmt) 19 2010 371 379
-
(2010)
J. Womens Health (Larchmt)
, vol.19
, pp. 371-379
-
-
Espeland, M.A.1
Shumaker, S.A.2
Limacher, M.3
Rapp, S.R.4
Bevers, T.B.5
Barad, D.H.6
Coker, L.H.7
Gaussoin, S.A.8
Stefanick, M.L.9
Lane, D.S.10
Maki, P.M.11
Resnick, S.M.12
-
91
-
-
84857366519
-
Sustained efficacy and safety of bazedoxifene in preventing fractures in postmenopausal women with osteoporosis: Results of a 5-year, randomized, placebo-controlled study
-
S.L. Silverman, A.A. Chines, D.L. Kendler, A.W. Kung, C.S. Teglbjaerg, D. Felsenberg, N. Mairon, G.D. Constantine, and J.D. Adachi Sustained efficacy and safety of bazedoxifene in preventing fractures in postmenopausal women with osteoporosis: results of a 5-year, randomized, placebo-controlled study Osteoporos. Int. 23 2012 351 363
-
(2012)
Osteoporos. Int.
, vol.23
, pp. 351-363
-
-
Silverman, S.L.1
Chines, A.A.2
Kendler, D.L.3
Kung, A.W.4
Teglbjaerg, C.S.5
Felsenberg, D.6
Mairon, N.7
Constantine, G.D.8
Adachi, J.D.9
-
92
-
-
77949370016
-
A randomized, placebo- and active-controlled trial of bazedoxifene/conjugated estrogens (BZA/CE) for treatment of moderate to severe vulvar/vaginal atrophy in postmenopausal women
-
R. Kagan, R.S. Williams, K. Pan, S. Mirkin, and J.H. Pickar A randomized, placebo- and active-controlled trial of bazedoxifene/conjugated estrogens (BZA/CE) for treatment of moderate to severe vulvar/vaginal atrophy in postmenopausal women Menopause 17 2010 281 289
-
(2010)
Menopause
, vol.17
, pp. 281-289
-
-
Kagan, R.1
Williams, R.S.2
Pan, K.3
Mirkin, S.4
Pickar, J.H.5
-
93
-
-
84885050196
-
Tissue selectivity of ospemifene: Pharmacologic profile and clinical implications
-
L. Kangas, and M. Unkila Tissue selectivity of ospemifene: pharmacologic profile and clinical implications Steroids 78 2013 1273 1280
-
(2013)
Steroids
, vol.78
, pp. 1273-1280
-
-
Kangas, L.1
Unkila, M.2
-
94
-
-
0642306447
-
Effects of ospemifene, a novel SERM, on vascular markers and function in healthy, postmenopausal women
-
O. Ylikorkala, B. Cacciatore, K. Halonen, R. Lassila, R. Lammintausta, E.M. Rutanen, J. Heikkinen, and J. Komi Effects of ospemifene, a novel SERM, on vascular markers and function in healthy, postmenopausal women Menopause 10 2003 440 447
-
(2003)
Menopause
, vol.10
, pp. 440-447
-
-
Ylikorkala, O.1
Cacciatore, B.2
Halonen, K.3
Lassila, R.4
Lammintausta, R.5
Rutanen, E.M.6
Heikkinen, J.7
Komi, J.8
-
95
-
-
0035991549
-
Phase III randomized trial of droloxifene and tamoxifen as first-line endocrine treatment of ER/PgR-positive advanced breast cancer
-
A. Buzdar, D. Hayes, A. El-Khoudary, S. Yan, P. Lonning, M. Lichinitser, R. Gopal, G. Falkson, K. Pritchard, A. Lipton, K. Wolter, A. Lee, K. Fly, R. Chew, M. Alderdice, K. Burke, and P. Eisenber Phase III randomized trial of droloxifene and tamoxifen as first-line endocrine treatment of ER/PgR-positive advanced breast cancer Breast Cancer Res. Treat. 73 2002 161 175
-
(2002)
Breast Cancer Res. Treat.
, vol.73
, pp. 161-175
-
-
Buzdar, A.1
Hayes, D.2
El-Khoudary, A.3
Yan, S.4
Lonning, P.5
Lichinitser, M.6
Gopal, R.7
Falkson, G.8
Pritchard, K.9
Lipton, A.10
Wolter, K.11
Lee, A.12
Fly, K.13
Chew, R.14
Alderdice, M.15
Burke, K.16
Eisenber, P.17
-
96
-
-
32244444374
-
Emerging selective estrogen receptor modulators: Special focus on effects on coronary heart disease in postmenopausal women
-
T.E. Vogelvang, M.J. van der Mooren, V. Mijatovic, and P. Kenemans Emerging selective estrogen receptor modulators: special focus on effects on coronary heart disease in postmenopausal women Drugs 66 2006 191 221
-
(2006)
Drugs
, vol.66
, pp. 191-221
-
-
Vogelvang, T.E.1
Van Der Mooren, M.J.2
Mijatovic, V.3
Kenemans, P.4
-
97
-
-
42449158652
-
Selective estrogen receptor modulators: An update on recent clinical findings
-
W. Shelly, M.W. Draper, V. Krishnan, M. Wong, and R.B. Jaffe Selective estrogen receptor modulators: an update on recent clinical findings Obstet. Gynecol. Surv. 63 2008 163 181
-
(2008)
Obstet. Gynecol. Surv.
, vol.63
, pp. 163-181
-
-
Shelly, W.1
Draper, M.W.2
Krishnan, V.3
Wong, M.4
Jaffe, R.B.5
-
98
-
-
0036738995
-
Adverse events that are associated with the selective estrogen receptor modulator levormeloxifene in an aborted phase III osteoporosis treatment study
-
S.R. Goldstein, and N. Nanavati Adverse events that are associated with the selective estrogen receptor modulator levormeloxifene in an aborted phase III osteoporosis treatment study Am. J. Obstet. Gynecol. 187 2002 521 527
-
(2002)
Am. J. Obstet. Gynecol.
, vol.187
, pp. 521-527
-
-
Goldstein, S.R.1
Nanavati, N.2
-
99
-
-
33644775813
-
Arzoxifene: The development and clinical outcome of an ideal SERM
-
P.N. Munster Arzoxifene: the development and clinical outcome of an ideal SERM Expert Opin. Investig. Drugs 15 2006 317 326
-
(2006)
Expert Opin. Investig. Drugs
, vol.15
, pp. 317-326
-
-
Munster, P.N.1
-
100
-
-
84655166912
-
Gynecologic effects of arzoxifene in postmenopausal women with osteoporosis or low bone mass
-
S.R. Goldstein, H.P. Bhattoa, P. Neven, D.A. Cox, S.A. Dowsett, J. Alam, A. Sipos, and D. Muram Gynecologic effects of arzoxifene in postmenopausal women with osteoporosis or low bone mass Menopause 19 2012 41 47
-
(2012)
Menopause
, vol.19
, pp. 41-47
-
-
Goldstein, S.R.1
Bhattoa, H.P.2
Neven, P.3
Cox, D.A.4
Dowsett, S.A.5
Alam, J.6
Sipos, A.7
Muram, D.8
-
101
-
-
84875503848
-
Effects of bazedoxifene/conjugated estrogens on endometrial safety and bone in postmenopausal women
-
S. Mirkin, B.S. Komm, K. Pan, and A.A. Chines Effects of bazedoxifene/conjugated estrogens on endometrial safety and bone in postmenopausal women Climacteric 16 2013 338 346
-
(2013)
Climacteric
, vol.16
, pp. 338-346
-
-
Mirkin, S.1
Komm, B.S.2
Pan, K.3
Chines, A.A.4
-
102
-
-
68349129906
-
Relief of vasomotor symptoms with the tissue-selective estrogen complex containing bazedoxifene/conjugated estrogens: A randomized, controlled trial
-
J.V. Pinkerton, W.H. Utian, G.D. Constantine, S. Olivier, and J.H. Pickar Relief of vasomotor symptoms with the tissue-selective estrogen complex containing bazedoxifene/conjugated estrogens: a randomized, controlled trial Menopause 16 2009 1116 1124
-
(2009)
Menopause
, vol.16
, pp. 1116-1124
-
-
Pinkerton, J.V.1
Utian, W.H.2
Constantine, G.D.3
Olivier, S.4
Pickar, J.H.5
-
103
-
-
69049120132
-
Evaluation of bazedoxifene/conjugated estrogens for the treatment of menopausal symptoms and effects on metabolic bone parameters and overall safety profile
-
R.A. Lobo, J.V. Pinkerton, M.L.S. Gass, M.H. Dorin, S. Ronkin, J.H. Pickar, and G. Constantine Evaluation of bazedoxifene/conjugated estrogens for the treatment of menopausal symptoms and effects on metabolic bone parameters and overall safety profile Fertil. Steril. 92 2009 1025 1038
-
(2009)
Fertil. Steril.
, vol.92
, pp. 1025-1038
-
-
Lobo, R.A.1
Pinkerton, J.V.2
Gass, M.L.S.3
Dorin, M.H.4
Ronkin, S.5
Pickar, J.H.6
Constantine, G.7
-
104
-
-
69049085452
-
Endometrial effects of a tissue selective estrogen complex (TSEC) containing bazedoxifene/conjugated estrogens as a menopausal therapy
-
J.H. Pickar, I.-T. Yeh, G. Bachmann, and L. Speroff Endometrial effects of a tissue selective estrogen complex (TSEC) containing bazedoxifene/conjugated estrogens as a menopausal therapy Fertil. Steril. 92 2009 1018 1024
-
(2009)
Fertil. Steril.
, vol.92
, pp. 1018-1024
-
-
Pickar, J.H.1
Yeh, I.-T.2
Bachmann, G.3
Speroff, L.4
-
105
-
-
69049083661
-
Efficacy of tissue-selective estrogen complex (TSEC) of bazedoxifene/conjugated estrogens (BZA/CE) for osteoporosis prevention in at-risk postmenopausal women
-
R. Lindsay, J.C. Gallagher, R. Kagan, J.H. Pickar, and G. Constantine Efficacy of tissue-selective estrogen complex (TSEC) of bazedoxifene/conjugated estrogens (BZA/CE) for osteoporosis prevention in at-risk postmenopausal women Fertil. Steril. 92 2009 1045 1052
-
(2009)
Fertil. Steril.
, vol.92
, pp. 1045-1052
-
-
Lindsay, R.1
Gallagher, J.C.2
Kagan, R.3
Pickar, J.H.4
Constantine, G.5
-
106
-
-
84873407467
-
Breast density changes in a randomized controlled trial evaluating bazedoxifene/conjugated estrogens
-
J.A. Harvey, J.V. Pinkerton, E.C. Baracat, H. Shi, A.A. Chines, and S. Mirkin Breast density changes in a randomized controlled trial evaluating bazedoxifene/conjugated estrogens Menopause 20 2013 138 145
-
(2013)
Menopause
, vol.20
, pp. 138-145
-
-
Harvey, J.A.1
Pinkerton, J.V.2
Baracat, E.C.3
Shi, H.4
Chines, A.A.5
Mirkin, S.6
-
107
-
-
84879078406
-
Breast effects of bazedoxifene-conjugated estrogens: A randomized controlled trial
-
J.V. Pinkerton, J.A. Harvey, K. Pan, J.R. Thompson, K.A. Ryan, A.A. Chines, and S. Mirkin Breast effects of bazedoxifene-conjugated estrogens: a randomized controlled trial Obstet. Gynecol. 121 2013 959 968
-
(2013)
Obstet. Gynecol.
, vol.121
, pp. 959-968
-
-
Pinkerton, J.V.1
Harvey, J.A.2
Pan, K.3
Thompson, J.R.4
Ryan, K.A.5
Chines, A.A.6
Mirkin, S.7
-
108
-
-
69049112720
-
Bazedoxifene/conjugated estrogens (BZA/CE): Incidence of uterine bleeding in postmenopausal women
-
D.F. Archer, V. Lewis, B.R. Carr, S. Olivier, and J.H. Pickar Bazedoxifene/conjugated estrogens (BZA/CE): incidence of uterine bleeding in postmenopausal women Fertil. Steril. 92 2009 1039 1044
-
(2009)
Fertil. Steril.
, vol.92
, pp. 1039-1044
-
-
Archer, D.F.1
Lewis, V.2
Carr, B.R.3
Olivier, S.4
Pickar, J.H.5
-
109
-
-
84887446224
-
Tissue selective estrogen complex combinations with bazedoxifene/ conjugated estrogens as a model
-
J.V. Pinkerton, B.S. Komm, and S. Mirkin Tissue selective estrogen complex combinations with bazedoxifene/conjugated estrogens as a model Climacteric 16 2013 618 628
-
(2013)
Climacteric
, vol.16
, pp. 618-628
-
-
Pinkerton, J.V.1
Komm, B.S.2
Mirkin, S.3
|