Effects of tamoxifen on the sex determination gene and the activation of sex reversal in the developing gonad of mice

Toxicology

Volumn 321, Issue 1, 2014, Pages 89-95

  Yu, Mingxi ^a   Wang, Jingyun ^a   Liu, Wei ^a   Qin, Junwen ^b   Zhou, Quan ^c   Wang, Yongan ^a   Huang, Huihui ^b   Chen, Wenli ^d   Ma, Chao ^d  

^a DALIAN UNIVERSITY OF TECHNOLOGY   (China)

^b JINAN UNIVERSITY   (China)

^c THE FIRST AFFILIATED HOSPITAL OF JINAN UNIVERSITY   (China)

^d SOUTH CHINA NORMAL UNIVERSITY   (China)

Author keywords

Endocrine disrupting chemicals; Sex determination; Sex reversal; Tamoxifen

Indexed keywords

ESTRADIOL; FOXL2 PROTEIN; JAGGED1; MESSENGER RNA; PLATELET DERIVED GROWTH FACTOR ALPHA RECEPTOR; PROGESTERONE; PROTEIN; TAMOXIFEN; TESTOSTERONE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; GENE ACTIVATION; GENE EXPRESSION; GONAD DEVELOPMENT; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; LEYDIG CELL; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SERTOLI CELL; SEX DETERMINATION; SEX TRANSFORMATION; TESTIS; TESTIS DEVELOPMENT; TESTOSTERONE RELEASE; UPREGULATION;

ENDOCRINE-DISRUPTING CHEMICALS; SEX DETERMINATION; SEX REVERSAL; TAMOXIFEN;

ANALYSIS OF VARIANCE; ANIMALS; ANTI-MULLERIAN HORMONE; ANTINEOPLASTIC AGENTS, HORMONAL; ENDOCRINE DISRUPTORS; FEMALE; FORKHEAD TRANSCRIPTION FACTORS; GONADAL STEROID HORMONES; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; MALE; MICE; MICE, INBRED ICR; ORGAN CULTURE TECHNIQUES; OVARY; REAL-TIME POLYMERASE CHAIN REACTION; RECEPTOR, PLATELET-DERIVED GROWTH FACTOR BETA; RNA, MESSENGER; SEX DETERMINATION PROCESSES; SEX DIFFERENTIATION; SOX9 TRANSCRIPTION FACTOR; TAMOXIFEN; TESTIS;

EID: 84899868406     PISSN: 0300483X     EISSN: 18793185     Source Type: Journal    
DOI: 10.1016/j.tox.2014.04.006     Document Type: Article

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