Natural tetraponerines: A general synthesis and antiproliferative activity

Journal of Organic Chemistry

Volumn 79, Issue 9, 2014, Pages 3982-3991

  Bosque, Irene ^a   Gonzalez Gomez, Jose C ^a   Loza, María Isabel ^b   Brea, José ^b  

^a UNIVERSITY OF ALICANTE   (Spain)

^b UNIVERSITY OF SANTIAGO DE COMPOSTELA   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

CELL CULTURE; SYNTHESIS (CHEMICAL);

ANTI-PROLIFERATIVE ACTIVITIES; ANTICANCER ACTIVITIES; BREAST CARCINOMA CELLS; CROSS METATHESIS; CYTOTOXIC ACTIVITIES; GENERAL METHODOLOGIES; HUMAN CELL LINES; THERMODYNAMIC CONTROL;

CYTOTOXICITY;

ANTINEOPLASTIC AGENT; INDIUM; NATURAL PRODUCT; SULFINAMIDE; TETRAPONERINE; TETRAPONERINE T1; TETRAPONERINE T2; TETRAPONERINE T3; TETRAPONERINE T4; TETRAPONERINE T5; TETRAPONERINE T6; TETRAPONERINE T7; TETRAPONERINE T8; UNCLASSIFIED DRUG; BIOLOGICAL PRODUCT; FUSED HETEROCYCLIC RINGS;

ALLYLATION; AMINATION; AMINOALLYLATION; ANTINEOPLASTIC ACTIVITY; ANTIPROLIFERATIVE ACTIVITY; ARTICLE; CARCINOMA CELL; CHEMICAL MODIFICATION; CHIRALITY; CIS ISOMER; CONTROLLED STUDY; CYCLIZATION; CYTOTOXICITY; DENSITY FUNCTIONAL THEORY; DRUG SYNTHESIS; ENANTIOMER; HUMAN; HUMAN CELL; INFRARED SPECTROSCOPY; MCF 7 CELL LINE; RING CLOSING METATHESIS; STEREOCHEMISTRY; CELL PROLIFERATION; CHEMISTRY; CONFORMATION; DOSE RESPONSE; DRUG EFFECTS; DRUG SCREENING; STEREOISOMERISM; STRUCTURE ACTIVITY RELATION; SYNTHESIS;

ANTINEOPLASTIC AGENTS; BIOLOGICAL PRODUCTS; CELL PROLIFERATION; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG SCREENING ASSAYS, ANTITUMOR; HETEROCYCLIC COMPOUNDS, 3-RING; HUMANS; MCF-7 CELLS; MOLECULAR CONFORMATION; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84899867021     PISSN: 00223263     EISSN: 15206904     Source Type: Journal    
DOI: 10.1021/jo500446f     Document Type: Article

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