Combination of submicroemulsion and phospholipid complex for novel delivery of ursodeoxycholic acid

Pharmaceutical Development and Technology

Volumn 19, Issue 3, 2014, Pages 363-372

  Ma, Yue Qin ^a   Li, Gang ^a   Xu, Jiang Hong ^a   Zhang, Jing ^a   Zhang, Zeng Zhu ^a   Xiao, Han Yang ^a   Li, Xian Fei ^a  

^a The 94th Hospital of PLA   (China)

Author keywords

Box Behnken design; Pharmacokinetic evaluation; Process optimization; UA SME loaded with UA PS

Indexed keywords

GLYCYRRHETINIC ACID PHOSPHOLIPID COMPLEX; URSODEOXYCHOLIC ACID;

ANIMAL EXPERIMENT; AREA UNDER THE CURVE; ARTICLE; DISPERSION; DRUG BIOAVAILABILITY; DRUG BLOOD LEVEL; DRUG SCREENING; DRUG SYNTHESIS; HYDROPHILICITY; LIPOPHILICITY; MALE; MAXIMUM PLASMA CONCENTRATION; MICROEMULSION; NONHUMAN; PARTICLE SIZE; PRIORITY JOURNAL; RAT; RESPONSE SURFACE METHOD; SINGLE DRUG DOSE; TIME TO MAXIMUM PLASMA CONCENTRATION; VELOCITY;

ADMINISTRATION, ORAL; ANIMALS; BIOLOGICAL AVAILABILITY; CHOLAGOGUES AND CHOLERETICS; EMULSIONS; MALE; PARTICLE SIZE; PHOSPHOLIPIDS; RATS; RATS, WISTAR; URSODEOXYCHOLIC ACID;

EID: 84899853089     PISSN: 10837450     EISSN: 10979867     Source Type: Journal    
DOI: 10.3109/10837450.2013.788517     Document Type: Article

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