Preparation, characterization, and bioavailability of ursodeoxycholic acid-phospholipid complex in vivo

Drug Development and Industrial Pharmacy

Volumn 34, Issue 7, 2008, Pages 708-718

  Yue, Peng Fei ^a,b   Yuan, Hai Long ^a   Xie, Huan ^a   Xiao, Xiao He ^a   Yang, Ming ^b   Liao, Mei Xiang ^b   Zhu, Wei Feng ^b   Cai, Pei Lie ^c  

^a BEIJING 302 HOSPITAL   (China)

^b BEIJING UNIVERSITY OF POSTS AND TELECOMMUNICATIONS   (China)

^c Huiren Group   (China)

Author keywords

Bioavailability; Derivatization; Phospholipid complex; Physicochemical properties; Ursodeoxycholic acid

Indexed keywords

OCTANOL; PHOSPHOLIPID; TETRAHYDROFURAN; URSODEOXYCHOLIC ACID; WATER;

ANIMAL EXPERIMENT; AREA UNDER THE CURVE; ARTICLE; COMPUTER PROGRAM; CONTROLLED STUDY; COVALENT BOND; DIFFERENTIAL SCANNING CALORIMETRY; DRUG BIOAVAILABILITY; DRUG BLOOD LEVEL; DRUG DOSAGE FORM COMPARISON; DRUG SYNTHESIS; EVAPORATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IN VIVO STUDY; MALE; NONHUMAN; PARTICLE SIZE; PARTITION COEFFICIENT; PHYSICAL CHEMISTRY; RAT; SCANNING ELECTRON MICROSCOPY; TABLET FORMULATION; TRANSMISSION ELECTRON MICROSCOPY; X RAY DIFFRACTION;

ADMINISTRATION, ORAL; ANIMALS; AREA UNDER CURVE; BIOLOGICAL AVAILABILITY; CALORIMETRY, DIFFERENTIAL SCANNING; CHEMISTRY, PHARMACEUTICAL; CHOLAGOGUES AND CHOLERETICS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DRUG CARRIERS; MALE; MICROSCOPY, ELECTRON, SCANNING; MICROSCOPY, ELECTRON, TRANSMISSION; PARTICLE SIZE; PHOSPHOLIPIDS; RATS; RATS, WISTAR; TABLETS; URSODEOXYCHOLIC ACID; X-RAY DIFFRACTION;

EID: 47049110188     PISSN: 03639045     EISSN: 15205762     Source Type: Journal    
DOI: 10.1080/03639040701842477     Document Type: Article

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