Design, synthesis and in-vitro evaluation of polymer-linked prodrug of methotrexate for the targeted delivery to the colon

Letters in Drug Design and Discovery

Volumn 11, Issue 5, 2014, Pages 601-610

  Singla, Nishu ^a   Sharma, Rajiv ^a   Bhardwaj, T R ^a  

^a ISF COLLEGE OF PHARMACY   (India)

Author keywords

Cancer; Chitosan; Drug conjugate; Polymer; Polyphosphazene; Prodrug

Indexed keywords

CHITOSAN; METHOTREXATE; POLY(ANILINO)[2 [[4 [2,4 BIS(4 HYDROXYPHEN 1YLDIAZO)]PTERIDINE 6 YL]METHYL](METHYL AMINE)BENZOYLGLUTAMIC ACID PHOSPHAZENE; POLY(P HYDROXYACETANILIDE)[2 [[4 [2,4 BIS(4 HYDROXYPHEN 1YLDIAZO)]PTERIDINE 6 YL]METHYL](METHYLAMINE)BENZOYLGLUTAMIC ACID]PHOSPHAZENE; POLY(P HYDROXYPROPYLBENZOATE)[2 [4 [2,4 BIS(4 HYDROXYPHEN 1YLDIAZO)]PTERIDINE 6 YL]METHYL](METHYLAMINE)BENZOYLGLUTAMIC ACID]PHOSPHAZENE; POLY(PHENOXY)[2 [[4 [2,4 BIS(4 HYDROXYPHEN 1YLDIAZO)]PTERIDINE 6 YL]METHYL](METHYL AMINE)BENZOYL GLUTAMIC ACID]PHOSPHAZENE; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; COLON; COMPARATIVE STUDY; CONJUGATE; CONTROLLED STUDY; DRUG DELIVERY SYSTEM; DRUG DESIGN; DRUG RELEASE; DRUG SYNTHESIS; GEL PERMEATION CHROMATOGRAPHY; IN VITRO STUDY; MOLECULAR WEIGHT; NONHUMAN; PH; PHOSPHORUS NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; RAT; SMALL INTESTINE;

EID: 84899847435     PISSN: 15701808     EISSN: 1875628X     Source Type: Journal    
DOI: 10.2174/1570180811666131217002719     Document Type: Article

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