Impact of urine concentration adjustment method on associations between urine metals and estimated glomerular filtration rates (eGFR) in adolescents

Environmental Research

Volumn 132, Issue , 2014, Pages 226-232

  Weaver, Virginia M ^a,b,c   Vargas, Gonzalo García ^d,e   Silbergeld, Ellen K ^a   Rothenberg, Stephen J ^f   Fadrowski, Jeffrey J ^b,c   Rubio Andrade, Marisela ^d   Parsons, Patrick J ^g,h   Steuerwald, Amy J ^g   Navas Acien, Ana ^a,c,i   Guallar, Eliseo ^b,c,i  

^a JOHNS HOPKINS UNIVERSITY   (United States)

^b JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c JOHNS HOPKINS UNIVERSITY   (United States)

^d UNIVERSIDAD JUÁREZ DEL ESTADO DE DURANGO   (Mexico)

^e Secretaría de Salud del Estado de Coahuila   (Mexico)

^f INSTITUTO NACIONAL DE SALUD PÚBLICA   (Mexico)

^g WADSWORTH CENTER   (United States)

^h STATE UNIVERSITY OF NEW YORK   (United States)

ⁱ JOHNS HOPKINS BLOOMBERG SCHOOL OF PUBLIC HEALTH   (United States)

Author keywords

Cadmium; Creatinine; Osmolality; Uranium; Urine concentration

Indexed keywords

CADMIUM; CREATININE; CYSTATIN C; LEAD; METAL DERIVATIVE; THALLIUM; URANIUM;

ADULT; CONCENTRATION (COMPOSITION); FILTRATION; HEALTH MONITORING; HEAVY METAL; SERUM; URINE;

ADOLESCENT; ARTICLE; CHILD; CLINICAL ASSESSMENT; CREATININE BLOOD LEVEL; CREATININE URINE LEVEL; CROSS-SECTIONAL STUDY; ENVIRONMENTAL EXPOSURE; ESTIMATED GLOMERULAR FILTRATION RATE; FEMALE; GLOMERULUS FILTRATION RATE; HUMAN; KIDNEY CONCENTRATING CAPACITY; KIDNEY FUNCTION; LABORATORY TEST; LEAD BLOOD LEVEL; MALE; MULTIPLE LINEAR REGRESSION ANALYSIS; NEPHROTOXICITY; PRIORITY JOURNAL; SERUM; URINALYSIS; URINE OSMOLALITY;

CADMIUM; CREATININE; OSMOLALITY; URANIUM; URINE CONCENTRATION;

ADOLESCENT; CHILD; CROSS-SECTIONAL STUDIES; ENVIRONMENTAL MONITORING; EXTRACTION AND PROCESSING INDUSTRY; FEMALE; GLOMERULAR FILTRATION RATE; HUMANS; MALE; METALS, HEAVY;

EID: 84899840047     PISSN: 00139351     EISSN: 10960953     Source Type: Journal    
DOI: 10.1016/j.envres.2014.04.013     Document Type: Article

References (35)

1. Agresti A. Categorical Data Analysis 2002, Wiley-Interscience, Hoboken, NJ, USA.
2. Akerstrom M., et al. The relationship between cadmium in kidney and cadmium in urine and blood in an environmentally exposed population. Toxicol. Appl. Pharmacol. 2013, 268:286-293.
3. Akerstrom M., et al. Associations between urinary excretion of cadmium and proteins in a nonsmoking population: renal toxicity or normal physiology?. Environ. Health Perspect. 2013, 121:187-191.
4. Akesson A., et al. Tubular and glomerular kidney effects in Swedish women with low environmental cadmium exposure. Environ. Health Perspect. 2005, 113:1627-1631.
5. Barr D.B., et al. Urinary creatinine concentrations in the U.S. population: implications for urinary biologic monitoring measurements. Environ. Health Perspect. 2005, 113:192-200.
6. Benin A.L., et al. High concentrations of heavy metals in neighborhoods near ore smelters in northern Mexico. Environ. Health Perspect. 1999, 107:279-284.
7. Boeniger M.F., et al. Interpretation of urine results used to assess chemical exposure with emphasis on creatinine adjustments: a review. Am. Ind. Hyg. Assoc. J. 1993, 54:615-627.
8. Chaumont A., et al. Associations between proteins and heavy metals in urine at low environmental exposures: evidence of reverse causality. Toxicol. Lett. 2012, 210:345-352.
9. Chen, X., et al., 2003. Regression with Stata. Stata Web Book. (Chapter 2). Available: http://www.ats.ucla.edu/stat/stata/webbooks/reg/default.htm.
10. Ciarimboli G., et al. Proximal tubular secretion of creatinine by organic cation transporter OCT2 in cancer patients. Clin. Cancer Res. 2012, 18:1101-1108.
11. de Burbure C., et al. Renal and neurologic effects of cadmium, lead, mercury, and arsenic in children: evidence of early effects and multiple interactions at environmental exposure levels. Environ. Health Perspect. 2006, 114:584-590.
12. Eisner C., et al. Major contribution of tubular secretion to creatinine clearance in mice. Kidney Int. 2010, 77:519-526.
13. Ferraro P.M., et al. Low level exposure to cadmium increases the risk of chronic kidney disease: analysis of the NHANES 1999-2006. BMC Public Health 2010, 10:304.
14. Filler G., Lepage N. Should the Schwartz formula for estimation of GFR be replaced by cystatin C formula?. Pediatr. Nephrol. 2003, 18:981-985.
15. Garcia Vargas G.G., et al. Lead exposure in children living in a smelter community in region Lagunera, Mexico. J. Toxicol. Environ. Health A 2001, 62:417-429.
16. Khalil-Manesh F., et al. Experimental model of lead nephropathy. I. Continuous high-dose lead administration. Kidney Int. 1992, 41:1192-1203.
17. Kurttio P., et al. Kidney toxicity of ingested uranium from drinking water. Am. J. Kidney Dis. 2006, 47:972-982.
18. Miller D.T., et al. Determination of lead in blood using electrothermal atomisation atomic absorption spectrometry with a L[U+05F3]vov platform and matrix modifier. Analyst 1987, 112:1701-1704.
19. Minnich M.G., et al. Determination of As, Cd, Pb, and Hg in urine using inductively coupled plasma mass spectrometry with the direct injection high efficiency nebulizer. Spectrochim. Acta Part B: At. Spectrosc. 2008, 63:389-395.
20. Moriguchi J., et al. Comparative evaluation of four urinary tubular dysfunction markers, with special references to the effects of aging and correction for creatinine concentration. Toxicol. Lett. 2003, 143:279-290.
21. Muscat J.E., et al. A comparison of creatinine vs. specific gravity to correct for urinary dilution of cotinine. Biomarkers 2011, 16:206-211.
22. Recio-Vega R., et al. Surveillance of elevated blood lead levels in children in Torreon, Coahuila, Mexico, 1998-2010. Int. J. Hyg. Environ. Health 2012, 215:507-513.
23. Schwartz G.J., et al. New equations to estimate GFR in children with CKD. J. Am. Soc. Nephrol. 2009, 20:629-637.
24. Shelley R., et al. Associations of multiple metals with kidney outcomes in lead workers. Occup. Environ. Med. 2012, 69:727-735.
25. Shelley R. Uranium associations with kidney outcomes vary by the urine concentration adjustment method. J. Expo. Sci. Environ. Epidemiol. 2014, 24(1):58-64.
26. Soodvilai S., et al. Renal organic cation transporters mediated cadmium-induced nephrotoxicity. Toxicol. Lett. 2011, 204:38-42.
27. Soto-Jimenez M.F., Flegal A.R. Childhood lead poisoning from the smelter in Torreon, Mexico. Environ. Res. 2011, 111:590-596.
28. Suwazono Y., et al. Creatinine versus specific gravity-adjusted urinary cadmium concentrations. Biomarkers 2005, 10:117-126.
29. Tanigawara Y., et al. Moment analysis of drug disposition in kidney. III: transport of p-aminohippurate and tetraethylammonium in the perfused kidney isolated from uranyl nitrate-induced acute renal failure rats. J. Pharm. Sci. 1990, 79:249-256.
30. Urakami Y., et al. Creatinine transport by basolateral organic cation transporter hOCT2 in the human kidney. Pharm. Res. 2004, 21:976-981.
31. Van Kerkhove E., et al. Cadmium and transport of ions and substances across cell membranes and epithelia. Biometals 2010, 23:823-855.
32. Weaver V.M., et al. Associations of low-level urine cadmium with kidney function in lead workers. Occup. Environ. Med. 2011, 68:250-256.
33. Weaver V.M., et al. Differences in urine cadmium associations with kidney outcomes based on serum creatinine and cystatin C. Environ. Res. 2011, 111:1236-1242.
34. Weisberg S. Applied Linear Regression 1985, John Wiley & Sons, New York.
35. You L., et al. Renal function, bisphenol A, and alkylphenols: results from the National Health and Nutrition Examination Survey (NHANES 2003-2006). Environ. Health Perspect. 2011, 119:527-533.