Differences in urine cadmium associations with kidney outcomes based on serum creatinine and cystatin C

Environmental Research

Volumn 111, Issue 8, 2011, Pages 1236-1242

  Weaver, Virginia M ^a,b,c   Kim, Nam Soo ^d   Lee, Byung Kook ^d   Parsons, Patrick J ^e,f   Spector, June ^g   Fadrowski, Jeffrey ^b,c   Jaar, Bernard G ^a,b,c   Steuerwald, Amy J ^e,f   Todd, Andrew C ^h   Simon, David ⁱ   Schwartz, Brian S ^a,b  

^a JOHNS HOPKINS BLOOMBERG SCHOOL OF PUBLIC HEALTH   (United States)

^b JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c JOHNS HOPKINS UNIVERSITY   (United States)

^d Soonchunhyang University   (South Korea)

^e WADSWORTH CENTER   (United States)

^f STATE UNIVERSITY OF NEW YORK   (United States)

^g UNIVERSITY OF WASHINGTON   (United States)

^h MOUNT SINAI SCHOOL OF MEDICINE   (United States)

ⁱ Biostatistical Consulting   (United States)

Author keywords

Cadmium; Cystatin C; Kidney function; Serum creatinine; Urine creatinine

Indexed keywords

BIOLOGICAL MARKER; CADMIUM; CREATININE; CYSTATIN C;

ABNORMALITY; BIOACCUMULATION; BIOCHEMISTRY; BIOMARKER; CADMIUM; DIET; FILTRATION; FUNCTIONAL ROLE; OCCUPATIONAL EXPOSURE; PHYSIOLOGY; POLLUTION EXPOSURE; SERUM; TOXIC MATERIAL; URINE;

ADULT; AGED; ARTICLE; CONTROLLED STUDY; CORRELATION ANALYSIS; CREATININE BLOOD LEVEL; CREATININE URINE LEVEL; FEMALE; GLOMERULUS FILTRATION RATE; HUMAN; KIDNEY FUNCTION; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL;

ADULT; CADMIUM; CREATININE; CROSS-SECTIONAL STUDIES; CYSTATIN C; FEMALE; GLOMERULAR FILTRATION RATE; HUMANS; KIDNEY; MALE; MIDDLE AGED;

EID: 80755163512     PISSN: 00139351     EISSN: 10960953     Source Type: Journal    
DOI: 10.1016/j.envres.2011.07.012     Document Type: Article

References (35)

1. Akesson A., Lundh T., Vahter M., Bjellerup P., Lidfeldt J., Nerbrand C., Samsioe G., Stromberg U., Skerfving S. Tubular and glomerular kidney effects in Swedish women with low environmental cadmium exposure. Environ. Health Perspect. 2005, 113:1627-1631.
2. Barr D.B., Wilder L.C., Caudill S.P., Gonzalez A.J., Needham L.L., Pirkle J.L. Urinary creatinine concentrations in the U.S. population: implications for urinary biologic monitoring measurements. Environ. Health Perspect. 2005, 113:192-200.
3. de Burbure C., Buchet J.P., Leroyer A., Nisse C., Haguenoer J.M., Mutti A., Smerhovsky Z., Cikrt M., Trzcinka-Ochocka M., Razniewska G., Jakubowski M., Bernard A. Renal and neurologic effects of cadmium, lead, mercury, and arsenic in children: evidence of early effects and multiple interactions at environmental exposure levels. Environ. Health Perspect. 2006, 114:584-590.
4. Dharnidharka V.R., Kwon C., Stevens G. Serum cystatin C is superior to serum creatinine as a marker of kidney function: a meta-analysis. Am. J. Kidney Dis. 2002, 40:221-226.
5. Eisner C., Faulhaber-Walter R., Wang Y., Leelahavanichkul A., Yuen P.S., Mizel D., Star R.A., Briggs J.P., Levine M., Schnermann J. Major contribution of tubular secretion to creatinine clearance in mice. Kidney Int. 2010, 77:519-526.
6. Fernandez F.J. Micromethod for lead determination in whole blood by atomic absorption, with use of the graphite furnace. Clin. Chem. 1975, 21:558-561.
7. Fried L.F. Creatinine and cystatin C: what are the values?. Kidney Int. 2009, 75:578-580.
8. Gena P., Calamita G., Guggino W.B. Cadmium impairs albumin reabsorption by downregulating megalin and ClC5 channels in renal proximal tubule cells. Environ. Health Perspect 2010.
9. Hellstrom L., Elinder C.G., Dahlberg B., Lundberg M., Jarup L., Persson B., Axelson O. Cadmium exposure and end-stage renal disease. Am. J. Kidney Dis. 2001, 38:1001-1008.
10. Jarrett J.M., Xiao G., Caldwell K.L., Henahan D., Shakirova G., Jones R.L. Eliminating molybdenum oxide interference in urine cadmium biomonitoring using ICP-DRC-MS. J. Anal. Atomic Spect. 2008, 23:962-967.
11. Kaseda R., Iino N., Hosojima M., Takeda T., Hosaka K., Kobayashi A., Yamamoto K., Suzuki A., Kasai A., Suzuki Y., Gejyo F., Saito A. Megalin-mediated endocytosis of cystatin C in proximal tubule cells. Biochem. Biophys. Res. Commun. 2007, 357:1130-1134.
12. Kido T., Nordberg G.F., Roels H.A. Cadmium-induced renal effects. Clinical Nephrotoxins: Renal Injury from Drugs and Chemicals 2003, 507-530. Kluwer Academic Publishers, Dordrecht. M.E. De Broe (Ed.).
13. Levey A.S., Bosch J.P., Lewis J.B., Greene T., Rogers N., Roth D. A more accurate method to estimate glomerular filtration rate from serum creatinine: a new prediction equation. modification of diet in renal disease study group. Ann. Intern. Med. 1999, 130:461-470.
14. Levey A.S., Greene T., Kusek J.W., Beck G.J., Group M.S. A simplified equation to predict glomerular filtration rate from serum creatinine. J. Am. Soc. Nephrol. 2000, 11:A0828.
15. Madero M., Sarnak M.J., Stevens L.A. Serum cystatin C as a marker of glomerular filtration rate. Curr. Opin. Nephrol. Hypertens. 2006, 15:610-616.
16. Manetti L., Pardini E., Genovesi M., Campomori A., Grasso L., Morselli L.L., Lupi I., Pellegrini G., Bartalena L., Bogazzi F., Martino E. Thyroid function differently affects serum cystatin C and creatinine concentrations. J. Endocrinol. Invest. 2005, 28:346-349.
17. Minnich M.G., Miller D.C., Parsons P.J. Determination of As, Cd, Pb, and Hg in urine using inductively coupled plasma mass spectrometry with the direct injection high efficiency nebulizer. Spectrochim. Acta Part B: Atomic Spectrosc. 2008, 63:389-395.
18. Navas-Acien A., Tellez-Plaza M., Guallar E., Muntner P., Silbergeld E., Jaar B., Weaver V. Blood Cadmium and Lead and Chronic Kidney Disease in US Adults: A Joint Analysis. Am. J. Epidemiol. 2009, 170:1156-1164.
19. Reinsch C.H. Smoothing by spline functions. Numerische Mathematik 1967, 10:177-183.
20. Roos J.F., Doust J., Tett S.E., Kirkpatrick C.M. Diagnostic accuracy of cystatin C compared to serum creatinine for the estimation of renal dysfunction in adults and children-a meta-analysis. Clin. Biochem. 2007, 40:383-391.
21. Rose B., Post T. Secretory Pathways in Proximal Tubule. UpToDate 2010, Waltham, MA.
22. Schwartz B.S., Lee B.K., Lee G.S., Stewart W.F., Lee S.S., Hwang K.Y., Ahn K.D., Kim Y.B., Bolla K.I., Simon D., Parsons P.J., Todd A.C. Associations of blood lead, dimercaptosuccinic acid-chelatable lead, and tibia lead with neurobehavioral test scores in South Korean lead workers. Am. J. Epidemiol. 2001, 153:453-464.
23. Staessen J.A., Nawrot T., Hond E.D., Thijs L., Fagard R., Hoppenbrouwers K., Koppen G., Nelen V., Schoeters G., Vanderschueren D., Van Hecke E., Verschaeve L., Vlietinck R., Roels H.A. Renal function, cytogenetic measurements, and sexual development in adolescents in relation to environmental pollutants: a feasibility study of biomarkers. Lancet 2001, 357:1660-1669.
24. Stevens L., Perrone R.D. Drugs that Elevate the Serum Creatinine Concentration. UpToDate 2010, Waltham, MA.
25. Stevens L.A., Coresh J., Schmid C.H., Feldman H.I., Froissart M., Kusek J., Rossert J., Van Lente F., Bruce R.D., Zhang Y.L., Greene T., Levey A.S. Estimating GFR using serum cystatin C alone and in combination with serum creatinine: a pooled analysis of 3418 individuals with CKD. Am. J. Kidney Dis. 2008, 51:395-406.
26. Stevens L.A., Schmid C.H., Greene T., Li L., Beck G.J., Joffe M.M., Froissart M., Kusek J.W., Zhang Y.L., Coresh J., Levey A.S. Factors other than glomerular filtration rate affect serum cystatin C levels. Kidney Int. 2009, 75:652-660.
27. Tidman M., Sjostrom P., Jones I. A Comparison of GFR estimating formulae based upon s-cystatin C and s-creatinine and a combination of the two. Nephrol. Dial. Transplant. 2008, 23:154-160.
28. Todd A.C. Contamination of in vivo bone-lead measurements. Phys. Med. Biol. 2000, 45:229-240.
29. Todd A.C., Chettle D.R. Calculating the uncertainty in lead concentration for in vivo bone lead x-ray fluorescence. Phys. Med. Biol. 2003, 48:2033-2039.
30. Todd A.C., Parsons P.J., Carroll S., Geraghty C., Khan F.A., Tang S., Moshier E.L. Measurements of lead in human tibiae. A comparison between K-shell X-ray fluorescence and electrothermal atomic absorption spectrometry. Phys. Med. Biol. 2002, 47:673-687.
31. Urakami Y., Kimura N., Okuda M., Inui K. Creatinine transport by basolateral organic cation transporter hOCT2 in the human kidney. Pharm. Res. 2004, 21:976-981.
32. Van Kerkhove E., Pennemans V., Swennen Q. Cadmium and transport of ions and substances across cell membranes and epithelia. Biometals. 2010, 23:823-855.
33. Weaver V.M., Kim N.S., Jaar B.G., Schwartz B.S., Parsons P.J., Steuerwald A.J., Todd A.C., Simon D., Lee B.K. Associations of low-level urine cadmium with kidney function in lead workers. Occup. Environ. Med. 2011, 68:250-256.
34. Weaver V.M., Lee B.K., Ahn K.D., Lee G.S., Todd A.C., Stewart W.F., Wen J., Simon D.J., Parsons P.J., Schwartz B.S. Associations of lead biomarkers with renal function in Korean lead workers. Occup. Environ. Med. 2003, 60:551-562.
35. Weisberg S. Applied Linear Regression 1985, John Wiley & Sons, New York.