-
1
-
-
0038784529
-
Are ubiquitination pathways central to Parkinson's disease?
-
DOI 10.1016/S0092-8674(03)00509-9
-
Giasson BI, Lee VM (2003) Are ubiquitination pathways central to Parkinson's disease? Cell 114: 1-8. (Pubitemid 36859837)
-
(2003)
Cell
, vol.114
, Issue.1
, pp. 1-8
-
-
Giasson, B.I.1
Lee, V.M.-Y.2
-
2
-
-
77449124047
-
Nedd4 and Nedd4-2: Closely related ubiquitin-protein ligases with distinct physiological functions
-
Yang B, Kumar S (2010) Nedd4 and Nedd4-2: closely related ubiquitin-protein ligases with distinct physiological functions. Cell Death Differ 17: 68-77.
-
(2010)
Cell Death Differ
, vol.17
, pp. 68-77
-
-
Yang, B.1
Kumar, S.2
-
3
-
-
33746196576
-
Nedd4-WW domain-binding protein 5 (Ndfip1) is associated with neuronal survival after acute cortical brain injury
-
Sang Q, Kim MH, Kumar S, Bye N, Morganti-Kossman MC, et al. (2006) Nedd4-WW domain-binding protein 5 (Ndfip1) is associated with neuronal survival after acute cortical brain injury. J Neurosci 26: 7234-7244.
-
(2006)
J Neurosci
, vol.26
, pp. 7234-7244
-
-
Sang, Q.1
Kim, M.H.2
Kumar, S.3
Bye, N.4
Morganti-Kossman, M.C.5
-
4
-
-
84863012466
-
Ndfip1 regulates nuclear Pten import in vivo to promote neuronal survival following cerebral ischemia
-
Howitt J, Lackovic J, Low LH, Naguib A, Macintyre A, et al. (2012) Ndfip1 regulates nuclear Pten import in vivo to promote neuronal survival following cerebral ischemia. J Cell Biol 196: 29-36.
-
(2012)
J Cell Biol
, vol.196
, pp. 29-36
-
-
Howitt, J.1
Lackovic, J.2
Low, L.H.3
Naguib, A.4
Macintyre, A.5
-
5
-
-
70349342931
-
Divalent metal transporter 1 (DMT1) regulation by Ndfip1 prevents metal toxicity in human neurons
-
Howitt J, Putz U, Lackovic J, Doan A, Dorstyn L, et al. (2009) Divalent metal transporter 1 (DMT1) regulation by Ndfip1 prevents metal toxicity in human neurons. Proc Natl Acad Sci U S A 106: 15489-15494.
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 15489-15494
-
-
Howitt, J.1
Putz, U.2
Lackovic, J.3
Doan, A.4
Dorstyn, L.5
-
6
-
-
84859897775
-
Differential regulation of Nedd4 ubiquitin ligases and their adaptor protein Ndfip1 in a rat model of ischemic stroke
-
Lackovic J, Howitt J, Callaway JK, Silke J, Bartlett P, et al. (2012) Differential regulation of Nedd4 ubiquitin ligases and their adaptor protein Ndfip1 in a rat model of ischemic stroke. Exp Neurol 235: 326-335.
-
(2012)
Exp Neurol
, vol.235
, pp. 326-335
-
-
Lackovic, J.1
Howitt, J.2
Callaway, J.K.3
Silke, J.4
Bartlett, P.5
-
7
-
-
58149158220
-
Regulation of the divalent metal ion transporter DMT1 and iron homeostasis by a ubiquitin-dependent mechanism involving Ndfips and WWP2
-
Foot NJ, Dalton HE, Shearwin-Whyatt LM, Dorstyn L, Tan SS, et al. (2008) Regulation of the divalent metal ion transporter DMT1 and iron homeostasis by a ubiquitin-dependent mechanism involving Ndfips and WWP2. Blood 112: 4268-4275.
-
(2008)
Blood
, vol.112
, pp. 4268-4275
-
-
Foot, N.J.1
Dalton, H.E.2
Shearwin-Whyatt, L.M.3
Dorstyn, L.4
Tan, S.S.5
-
8
-
-
78751542539
-
Ndfip1-deficient mice have impaired DMT1 regulation and iron homeostasis
-
Foot NJ, Leong YA, Dorstyn LE, Dalton HE, Ho K, et al. (2011) Ndfip1-deficient mice have impaired DMT1 regulation and iron homeostasis. Blood 117: 638-646.
-
(2011)
Blood
, vol.117
, pp. 638-646
-
-
Foot, N.J.1
Leong, Y.A.2
Dorstyn, L.E.3
Dalton, H.E.4
Ho, K.5
-
9
-
-
84864916880
-
Isoform specific regulation of divalent metal (ion) transporter (DMT1) by proteasomal degradation
-
Garrick MD, Zhao L, Roth JA, Jiang H, Feng J, et al. (2012) Isoform specific regulation of divalent metal (ion) transporter (DMT1) by proteasomal degradation. Biometals.
-
(2012)
Biometals
-
-
Garrick, M.D.1
Zhao, L.2
Roth, J.A.3
Jiang, H.4
Feng, J.5
-
10
-
-
57449092273
-
Divalent metal transporter 1 (DMT1) contributes to neurodegeneration in animal models of Parkinson's disease
-
Salazar J, Mena N, Hunot S, Prigent A, Alvarez-Fischer D, et al. (2008) Divalent metal transporter 1 (DMT1) contributes to neurodegeneration in animal models of Parkinson's disease. Proc Natl Acad Sci U S A 105: 18578-18583.
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, pp. 18578-18583
-
-
Salazar, J.1
Mena, N.2
Hunot, S.3
Prigent, A.4
Alvarez-Fischer, D.5
-
11
-
-
0009588941
-
-
Lewandowski M, editor. Berlin: Springer
-
Lewy FH (1912) In: Lewandowski M, editor. Handbuch der Neurologie Band III Berlin: Springer.
-
(1912)
Handbuch der Neurologie
, vol.III
-
-
Lewy, F.H.1
-
12
-
-
0030744876
-
Mutation in the alpha-synuclein gene identified in families with Parkinson's disease
-
DOI 10.1126/science.276.5321.2045
-
Polymeropoulos MH, Lavedan C, Leroy E, Ide SE, Dehejia A, et al. (1997) Mutation in the alpha-synuclein gene identified in families with Parkinson's disease. Science 276: 2045-2047. (Pubitemid 27443610)
-
(1997)
Science
, vol.276
, Issue.5321
, pp. 2045-2047
-
-
Polymeropoulos, M.H.1
Lavedan, C.2
Leroy, E.3
Ide, S.E.4
Dehejia, A.5
Dutra, A.6
Pike, B.7
Root, H.8
Rubenstein, J.9
Boyer, R.10
Stenroos, E.S.11
Chandrasekharappa, S.12
Athanassiadou, A.13
Papapetropoulos, T.14
Johnson, W.G.15
Lazzarini, A.M.16
Duvoisin, R.C.17
Di, I.G.18
Golbe, L.I.19
Nussbaum, R.L.20
more..
-
13
-
-
0030882856
-
Alpha-synuclein in Lewy bodies
-
Spillantini MG, Schmidt ML, Lee VM, Trojanowski JQ, Jakes R, et al. (1997) Alpha-synuclein in Lewy bodies. Nature 388: 839-840.
-
(1997)
Nature
, vol.388
, pp. 839-840
-
-
Spillantini, M.G.1
Schmidt, M.L.2
Lee, V.M.3
Trojanowski, J.Q.4
Jakes, R.5
-
14
-
-
34147107527
-
Assessment of brain iron and neuronal integrity in patients with Parkinson's disease using novel MRI contrasts
-
DOI 10.1002/mds.21227
-
Michaeli S, Oz G, Sorce DJ, Garwood M, Ugurbil K, et al. (2007) Assessment of brain iron and neuronal integrity in patients with Parkinson's disease using novel MRI contrasts. Mov Disord 22: 334-340. (Pubitemid 46569686)
-
(2007)
Movement Disorders
, vol.22
, Issue.3
, pp. 334-340
-
-
Michaeli, S.1
Oz, G.2
Sorce, D.J.3
Garwood, M.4
Ugurbil, K.5
Majestic, S.6
Tuite, P.7
-
15
-
-
11144353557
-
The relevance of iron in the pathogenesis of Parkinson's disease
-
DOI 10.1196/annals.1306.017
-
Gotz ME, Double K, Gerlach M, Youdim MB, Riederer P (2004) The relevance of iron in the pathogenesis of Parkinson's disease. Ann N Y Acad Sci 1012: 193-208. (Pubitemid 38455479)
-
(2004)
Annals of the New York Academy of Sciences
, vol.1012
, pp. 193-208
-
-
Gotz, M.E.1
Double, K.2
Gerlach, M.3
Youdim, M.B.H.4
Riederer, P.5
-
16
-
-
0030005267
-
Basal ganglia iron content in Parkinson's disease measured with magnetic resonance
-
DOI 10.1002/mds.870110305
-
Ye FQ, Allen PS, Martin WR (1996) Basal ganglia iron content in Parkinson's disease measured with magnetic resonance. Mov Disord 11: 243-249. (Pubitemid 26138821)
-
(1996)
Movement Disorders
, vol.11
, Issue.3
, pp. 243-249
-
-
Ye, F.Q.1
Allen, P.S.2
Martin, W.R.W.3
-
17
-
-
77949261597
-
Up-regulation of divalent metal transporter 1 in 6-hydroxydopamine intoxication is IRE/IRP dependent
-
Jiang H, Song N, Xu H, Zhang S, Wang J, et al. (2010) Up-regulation of divalent metal transporter 1 in 6-hydroxydopamine intoxication is IRE/IRP dependent. Cell Res 20: 345-356.
-
(2010)
Cell Res
, vol.20
, pp. 345-356
-
-
Jiang, H.1
Song, N.2
Xu, H.3
Zhang, S.4
Wang, J.5
-
18
-
-
0037354265
-
DMT1: A mammalian transporter for multiple metals
-
DOI 10.1023/A:1020702213099
-
Garrick MD, Dolan KG, Horbinski C, Ghio AJ, Higgins D, et al. (2003) DMT1: a mammalian transporter for multiple metals. Biometals 16: 41-54. (Pubitemid 36140214)
-
(2003)
BioMetals
, vol.16
, Issue.1
, pp. 41-54
-
-
Garrick, M.D.1
Dolan, K.G.2
Horbinski, C.3
Ghio, A.J.4
Higgins, D.5
Porubcin, M.6
Moore, E.G.7
Hainsworth, L.N.8
Umbreit, J.N.9
Conrad, M.E.10
Feng, L.11
Lis, A.12
Roth, J.A.13
Singleton, S.14
Garrick, L.M.15
-
19
-
-
0036942832
-
Consensus neuropathological diagnosis of common dementia syndromes: Testing and standardising the use of multiple diagnostic criteria
-
DOI 10.1007/s00401-002-0529-5
-
Halliday G, Ng T, Rodriguez M, Harding A, Blumbergs P, et al. (2002) Consensus neuropathological diagnosis of common dementia syndromes: testing and standardising the use of multiple diagnostic criteria. Acta Neuropathol 104: 72-78. (Pubitemid 36075361)
-
(2002)
Acta Neuropathologica
, vol.104
, Issue.1
, pp. 72-78
-
-
Halliday, G.1
Ng, T.2
Rodriguez, M.3
Harding, A.4
Blumbergs, P.5
Evans, W.6
Fabian, V.7
Fryer, J.8
Gonzales, M.9
Harper, C.10
Kalnins, R.11
Masters, C.L.12
McLean, C.13
Milder, D.G.14
Pamphlett, R.15
Scott, G.16
Tannenberg, A.17
Kril, J.18
-
20
-
-
0026629509
-
What features improve the accuracy of clinical diagnosis in Parkinson's disease: A clinicopathologic study
-
Hughes AJ, Ben-Shlomo Y, Daniel SE, Lees AJ (1992) What features improve the accuracy of clinical diagnosis in Parkinson's disease: a clinicopathologic study. Neurology 42: 1142-1146.
-
(1992)
Neurology
, vol.42
, pp. 1142-1146
-
-
Hughes, A.J.1
Ben-Shlomo, Y.2
Daniel, S.E.3
Lees, A.J.4
-
21
-
-
0037443602
-
Neurotoxicity from glutathione depletion is dependent on extracellular trace copper
-
DOI 10.1002/jnr.10537
-
White AR, Cappai R (2003) Neurotoxicity from glutathione depletion is dependent on extracellular trace copper. J Neurosci Res 71: 889-897. (Pubitemid 36293010)
-
(2003)
Journal of Neuroscience Research
, vol.71
, Issue.6
, pp. 889-897
-
-
White, A.R.1
Cappai, R.2
-
22
-
-
0023804321
-
Increased iron (III) and total iron content in post mortem substantia nigra of parkinsonian brain
-
Sofic E, Riederer P, Heinsen H, Beckmann H, Reynolds GP, et al. (1988) Increased iron (III) and total iron content in post mortem substantia nigra of parkinsonian brain. J Neural Transm 74: 199-205.
-
(1988)
J Neural Transm
, vol.74
, pp. 199-205
-
-
Sofic, E.1
Riederer, P.2
Heinsen, H.3
Beckmann, H.4
Reynolds, G.P.5
-
23
-
-
0026034279
-
Iron and aluminum increase in the substantia nigra of patients with parkinson's disease: An X-ray microanalysis
-
Hirsch EC, Brandel JP, Galle P, Javoy-Agid F, Agid Y (1991) Iron and aluminum increase in the substantia nigra of patients with Parkinson's disease: an X-ray microanalysis. J Neurochem 56: 446-451. (Pubitemid 21901982)
-
(1991)
Journal of Neurochemistry
, vol.56
, Issue.2
, pp. 446-451
-
-
Hirsch, E.C.1
Brandel, J.-P.2
Galle, P.3
Javoy-Agid, F.4
Agid, Y.5
-
24
-
-
0031716026
-
Dopamine agonists and neuroprotection in Parkinson's disease
-
Olanow CW, Jenner P, Brooks D (1998) Dopamine agonists and neuroprotection in Parkinson's disease. Ann Neurol 44: S167-174. (Pubitemid 28423845)
-
(1998)
Annals of Neurology
, vol.44
, Issue.3 SUPPL. 1
-
-
Olanow, C.W.1
Jenner, P.2
Brooks, D.3
-
25
-
-
0042433192
-
Neuromelanin associated redox-active iron is increased in the substantia nigra of patients with Parkinson's disease
-
Faucheux BA, Martin ME, Beaumont C, Hauw JJ, Agid Y, et al. (2003) Neuromelanin associated redox-active iron is increased in the substantia nigra of patients with Parkinson's disease. J Neurochem 86: 1142-1148. (Pubitemid 37022190)
-
(2003)
Journal of Neurochemistry
, vol.86
, Issue.5
, pp. 1142-1148
-
-
Faucheux, B.A.1
Martin, M.-E.2
Beaumont, C.3
Hauw, J.-J.4
Agid, Y.5
Hirsch, E.C.6
-
26
-
-
0035006792
-
Proteasome inhibition in oxidative stress neurotoxicity: Implications for heat shock proteins
-
DOI 10.1046/j.1471-4159.2001.00302.x
-
Ding Q, Keller JN (2001) Proteasome inhibition in oxidative stress neurotoxicity: implications for heat shock proteins. J Neurochem 77: 1010-1017. (Pubitemid 32467056)
-
(2001)
Journal of Neurochemistry
, vol.77
, Issue.4
, pp. 1010-1017
-
-
Ding, Q.1
Keller, J.N.2
-
27
-
-
70349736190
-
Degeneration in different parkinsonian syndromes relates to astrocyte type and astrocyte protein expression
-
Song YJ, Halliday GM, Holton JL, Lashley T, O'Sullivan SS, et al. (2009) Degeneration in different parkinsonian syndromes relates to astrocyte type and astrocyte protein expression. J Neuropathol Exp Neurol 68: 1073-1083.
-
(2009)
J Neuropathol Exp Neurol
, vol.68
, pp. 1073-1083
-
-
Song, Y.J.1
Halliday, G.M.2
Holton, J.L.3
Lashley, T.4
O'Sullivan, S.S.5
-
28
-
-
79953154057
-
Cellular upregulation of Nedd4 family interacting protein 1 (Ndfip1) using low levels of bioactive cobalt complexes
-
Schieber C, Howitt J, Putz U, White JM, Parish CL, et al. (2011) Cellular upregulation of Nedd4 family interacting protein 1 (Ndfip1) using low levels of bioactive cobalt complexes. J Biol Chem 286: 8555-8564.
-
(2011)
J Biol Chem
, vol.286
, pp. 8555-8564
-
-
Schieber, C.1
Howitt, J.2
Putz, U.3
White, J.M.4
Parish, C.L.5
-
29
-
-
19344376879
-
Hypoxia induces changes in expression of isoforms of the divalent metal transporter (DMT1) in rat pheochromocytoma (PC12) cells
-
DOI 10.1016/j.bcp.2005.03.023, PII S0006295205001772
-
Lis A, Paradkar PN, Singleton S, Kuo HC, Garrick MD, et al. (2005) Hypoxia induces changes in expression of isoforms of the divalent metal transporter (DMT1) in rat pheochromocytoma (PC12) cells. Biochem Pharmacol 69: 1647-1655. (Pubitemid 40719500)
-
(2005)
Biochemical Pharmacology
, vol.69
, Issue.11
, pp. 1647-1655
-
-
Lis, A.1
Paradkar, P.N.2
Singleton, S.3
Kuo, H.-C.4
Garrick, M.D.5
Roth, J.A.6
-
30
-
-
32944457363
-
Nitric oxide transcriptionally down-regulates specific isoforms of divalent metal transporter (DMT1) via NF-kappaB
-
DOI 10.1111/j.1471-4159.2006.03702.x
-
Paradkar PN, Roth JA (2006) Nitric oxide transcriptionally down-regulates specific isoforms of divalent metal transporter (DMT1) via NF-kappaB. J Neurochem 96: 1768-1777. (Pubitemid 43351634)
-
(2006)
Journal of Neurochemistry
, vol.96
, Issue.6
, pp. 1768-1777
-
-
Paradkar, P.N.1
Roth, J.A.2
-
31
-
-
0035941201
-
Metal-triggered structural transformations, aggregation, and fibrillation of human alpha-synuclein. A possible molecular NK between Parkinson's disease and heavy metal exposure
-
Uversky VN, Li J, Fink AL (2001) Metal-triggered structural transformations, aggregation, and fibrillation of human alpha-synuclein. A possible molecular NK between Parkinson's disease and heavy metal exposure. J Biol Chem 276: 44284-44296.
-
(2001)
J Biol Chem
, vol.276
, pp. 44284-44296
-
-
Uversky, V.N.1
Li, J.2
Fink, A.L.3
-
32
-
-
0035430788
-
Failure of the ubiquitin-proteasome system in Parkinson's disease
-
DOI 10.1038/35086067
-
McNaught KS, Olanow CW, Halliwell B, Isacson O, Jenner P (2001) Failure of the ubiquitin-proteasome system in Parkinson's disease. Nat Rev Neurosci 2: 589-594. (Pubitemid 33679832)
-
(2001)
Nature Reviews Neuroscience
, vol.2
, Issue.8
, pp. 589-594
-
-
McNaught, K.St.P.1
Olanow, C.W.2
Halliwell, B.3
Isacson, O.4
Jenner, P.5
-
33
-
-
77954914419
-
Regulation of PTEN/Akt and MAP kinase signaling pathways by the ubiquitin ligase activators Ndfip1 and Ndfip2
-
Mund T, Pelham HR (2010) Regulation of PTEN/Akt and MAP kinase signaling pathways by the ubiquitin ligase activators Ndfip1 and Ndfip2. Proc Natl Acad Sci U S A 107: 11429-11434.
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, pp. 11429-11434
-
-
Mund, T.1
Pelham, H.R.2
-
34
-
-
79951499176
-
Glia: Initiators and progressors of pathology in Parkinson's disease
-
Halliday GM, Stevens CH (2011) Glia: initiators and progressors of pathology in Parkinson's disease. Mov Disord 26: 6-17.
-
(2011)
Mov Disord
, vol.26
, pp. 6-17
-
-
Halliday, G.M.1
Stevens, C.H.2
|