Evaluation of several routes to advanced pregabalin intermediates: Synthesis and enantioselective enzymatic reduction using ene-reductases

Organic Process Research and Development

Volumn 18, Issue 1, 2014, Pages 109-121

  Debarge, Sébastien ^a   McDaid, Paul ^a   O'Neill, Pat ^a   Frahill, James ^a   Wong, John W ^a   Carr, Donncha ^a   Burrell, Adam ^a   Davies, Simon ^a   Karmilowicz, Mike ^a   Steflik, Jeremy ^a  

^a PFIZER INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMISTRY;

ASYMMETRIC REDUCTION; ENANTIOSELECTIVE; ENZYMATIC REDUCTION; LYCOPERSICON ESCULENTUM; STEREOCENTERS; SYNTHETIC ROUTES;

ENZYME ACTIVITY;

EID: 84899817347     PISSN: 10836160     EISSN: 1520586X     Source Type: Journal    
DOI: 10.1021/op4002774     Document Type: Article

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