Role of the hippocampus in Nav1.6 (Scn8a) mediated seizure resistance

Neurobiology of Disease

Volumn 68, Issue , 2014, Pages 16-25

  Makinson, Christopher D ^a   Tanaka, Brian S ^b   Lamar, Tyra ^a   Goldin, Alan L ^b   Escayg, Andrew ^a  

^a EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Cre recombinase; Dravet syndrome; Lentivirus; Nav1.1; Scn1a; Scn8a; Voltage gated sodium channel

Indexed keywords

CRE RECOMBINASE; LENTIVIRUS VECTOR; PICROTOXIN; POTASSIUM; SODIUM CHANNEL NAV1.1; SODIUM CHANNEL NAV1.2; SODIUM CHANNEL NAV1.6; CONVULSANT AGENT; GREEN FLUORESCENT PROTEIN; SCN1A PROTEIN, MOUSE; SCN8A PROTEIN, MOUSE;

ALLELE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN SLICE; CONTROLLED STUDY; DISEASE MODEL; DISEASE RESISTANCE; EPILEPTIC DISCHARGE; EPILEPTIFORM BURST DISCHARGE ACTIVITY; FEMALE; GENE DELETION; GENE EXPRESSION; GENE MUTATION; GENE SILENCING; HETEROZYGOSITY; HIPPOCAMPUS; KNOCKOUT MOUSE; MALE; MOUSE; NERVOUS SYSTEM DEVELOPMENT; NONHUMAN; PERINATAL PERIOD; PRIORITY JOURNAL; PROTEIN DEFICIENCY; PROTEIN FUNCTION; SCN1A GENE; SCN2A GENE; SCN8A GENE; SEIZURE; SEIZURE THRESHOLD; AGE; ANIMAL; C3H MOUSE; DRUG EFFECTS; GENETICS; IN VITRO STUDY; METABOLISM; MUTATION; NERVE CELL; NEWBORN; PATHOLOGY; PHYSIOLOGY; PSYCHOMOTOR PERFORMANCE; REACTION TIME; SEIZURES; TRANSGENIC MOUSE;

AGE FACTORS; ANIMALS; ANIMALS, NEWBORN; CONVULSANTS; DISEASE MODELS, ANIMAL; GREEN FLUORESCENT PROTEINS; HIPPOCAMPUS; IN VITRO TECHNIQUES; MICE; MICE, INBRED C3H; MICE, TRANSGENIC; MUTATION; NAV1.1 VOLTAGE-GATED SODIUM CHANNEL; NAV1.6 VOLTAGE-GATED SODIUM CHANNEL; NEURONS; POTASSIUM; PSYCHOMOTOR PERFORMANCE; REACTION TIME; SEIZURES;

EID: 84899799476     PISSN: 09699961     EISSN: 1095953X     Source Type: Journal    
DOI: 10.1016/j.nbd.2014.03.014     Document Type: Article

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