메뉴 건너뛰기




Volumn 30, Issue 5, 2014, Pages 166-172

Eculizumab: A guide to its use in atypical haemolytic uraemic syndrome

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENT; ECULIZUMAB; VON WILLEBRAND FACTOR CLEAVING PROTEINASE;

EID: 84899762902     PISSN: 11720360     EISSN: 11791977     Source Type: Journal    
DOI: 10.1007/s40267-014-0120-x     Document Type: Article
Times cited : (1)

References (29)
  • 1
    • 84860141031 scopus 로고    scopus 로고
    • A new era in the diagnosis and treatment of atypical haemolytic uraemic syndrome
    • Westra D, Wetzels JF, Volokhina EB, et al. A new era in the diagnosis and treatment of atypical haemolytic uraemic syndrome. Neth J Med. 2012;70(3):121-9.
    • (2012) Neth J Med , vol.70 , Issue.3 , pp. 121-129
    • Westra, D.1    Wetzels, J.F.2    Volokhina, E.B.3
  • 3
    • 84878589219 scopus 로고    scopus 로고
    • Terminal complement inhibitor eculizumab in atypical hemolytic-uremic syndrome
    • Legendre CM, Licht C, Muus P, et al. Terminal complement inhibitor eculizumab in atypical hemolytic-uremic syndrome. N Engl J Med. 2013;368(23):2169-81.
    • (2013) N Engl J Med , vol.368 , Issue.23 , pp. 2169-2181
    • Legendre, C.M.1    Licht, C.2    Muus, P.3
  • 4
    • 84873723582 scopus 로고    scopus 로고
    • An update for atypical haemolytic uraemic syndrome: Diagnosis and treatment: A consensus document
    • Campistol JM, Arias M, Ariceta G, et al. An update for atypical haemolytic uraemic syndrome: diagnosis and treatment: a consensus document. Nefrologia. 2013;33(1):27-45.
    • (2013) Nefrologia , vol.33 , Issue.1 , pp. 27-45
    • Campistol, J.M.1    Arias, M.2    Ariceta, G.3
  • 5
    • 79151471122 scopus 로고    scopus 로고
    • aHUS caused by complement dysregulation: New therapies on the horizon
    • Waters AM, Licht C. aHUS caused by complement dysregulation: new therapies on the horizon. Pediatr Nephrol. 2011;26(1):41-57.
    • (2011) Pediatr Nephrol , vol.26 , Issue.1 , pp. 41-57
    • Waters, A.M.1    Licht, C.2
  • 6
    • 84861618238 scopus 로고    scopus 로고
    • Clinical grand rounds: Atypical hemolytic uremic syndrome
    • Hodgkins KS, Bobrowski AE, Lane JC, et al. Clinical grand rounds: atypical hemolytic uremic syndrome. Am J Nephrol. 2012;35(5):394-400.
    • (2012) Am J Nephrol , vol.35 , Issue.5 , pp. 394-400
    • Hodgkins, K.S.1    Bobrowski, A.E.2    Lane, J.C.3
  • 7
    • 70350279315 scopus 로고    scopus 로고
    • Atypical hemolytic-uremic syndrome
    • Noris M, Remuzzi G. Atypical hemolytic-uremic syndrome. N Engl J Med. 2009;361(17):1676-87.
    • (2009) N Engl J Med , vol.361 , Issue.17 , pp. 1676-1687
    • Noris, M.1    Remuzzi, G.2
  • 8
    • 85081807847 scopus 로고    scopus 로고
    • Systemic multi-organ complications in atypical hemolytic uremic syndrome (aHUS): Retrospective study in a medical practice setting
    • abstract no. 0490
    • Langman C. Systemic multi-organ complications in atypical hemolytic uremic syndrome (aHUS): retrospective study in a medical practice setting [abstract no. 0490]. Haematologica. 2012;97(Suppl 1):195-6.
    • (2012) Haematologica , vol.97 , Issue.SUPPL. 1 , pp. 195-196
    • Langman, C.1
  • 9
    • 84867993256 scopus 로고    scopus 로고
    • Use of eculizumab for atypical haemolytic uraemic syndrome and C3 glomerulopathies
    • Zuber J, Fakhouri F, Roumenina LT, et al. Use of eculizumab for atypical haemolytic uraemic syndrome and C3 glomerulopathies. Nat Rev Nephrol. 2012;8(11):643-57.
    • (2012) Nat Rev Nephrol , vol.8 , Issue.11 , pp. 643-657
    • Zuber, J.1    Fakhouri, F.2    Roumenina, L.T.3
  • 10
    • 84872336333 scopus 로고    scopus 로고
    • Treatment of atypical hemolytic uremic syndrome and thrombotic microangiopathies: A focus on eculizumab
    • Schmidtko J, Peine S, El-Housseini Y, et al. Treatment of atypical hemolytic uremic syndrome and thrombotic microangiopathies: a focus on eculizumab. Am J Kidney Dis. 2013;61(2):289-99.
    • (2013) Am J Kidney Dis , vol.61 , Issue.2 , pp. 289-299
    • Schmidtko, J.1    Peine, S.2    El-Housseini, Y.3
  • 11
    • 84879350647 scopus 로고    scopus 로고
    • Atypical hemolytic uremic syndrome: What is it, how is it diagnosed, and how is it treated?
    • Nester CM, Thomas CP. Atypical hemolytic uremic syndrome: what is it, how is it diagnosed, and how is it treated? Hematol Am Soc Hematol Educ Program. 2012;2012:617-25.
    • (2012) Hematol Am Soc Hematol Educ Program , vol.2012 , pp. 617-625
    • Nester, C.M.1    Thomas, C.P.2
  • 12
    • 84883558622 scopus 로고    scopus 로고
    • Atypical hemolytic uremic syndrome: From the rediscovery of complement to targeted therapy
    • Fakhouri F, Fremeaux-Bacchi V, Loirat C. Atypical hemolytic uremic syndrome: from the rediscovery of complement to targeted therapy. Eur J Intern Med. 2013;24(6):492-5.
    • (2013) Eur J Intern Med , vol.24 , Issue.6 , pp. 492-495
    • Fakhouri, F.1    Fremeaux-Bacchi, V.2    Loirat, C.3
  • 16
    • 84892579246 scopus 로고    scopus 로고
    • Eculizumab: A review of its use in atypical haemololytic uraemic syndrome
    • Keating GM. Eculizumab: a review of its use in atypical haemololytic uraemic syndrome. Drugs. 2013;73(18):2053-66.
    • (2013) Drugs , vol.73 , Issue.18 , pp. 2053-2066
    • Keating, G.M.1
  • 17
    • 85081808547 scopus 로고    scopus 로고
    • Eculizumab (ECU) inhibits thrombotic microangiopathy (TMA) and improves renal function in adult atypical hemolytic uremic syndrome (aHUS) patients (pts)
    • abstract 5-10 Nov 2013; Atlanta (GA)
    • Fakhouri F, Hourmant M, Campistol JM, et al. Eculizumab (ECU) inhibits thrombotic microangiopathy (TMA) and improves renal function in adult atypical hemolytic uremic syndrome (aHUS) patients (pts) [abstract]. In: Kidney Week 2013; 5-10 Nov 2013; Atlanta (GA).
    • (2013) Kidney Week
    • Fakhouri, F.1    Hourmant, M.2    Campistol, J.M.3
  • 18
    • 84892576159 scopus 로고    scopus 로고
    • Eculizumab (ECU) inhibits thrombotic microangiopathy (TMA) and improves renal function in pediatric atypical hemolytic uremic syndrome (aHUS) patients (pts)
    • abstract 5-10 Nov 2013; Atlanta (GA)
    • Greenbaum LA, Fila M, Tsimaratos M, et al. Eculizumab (ECU) inhibits thrombotic microangiopathy (TMA) and improves renal function in pediatric atypical hemolytic uremic syndrome (aHUS) patients (pts) [abstract]. In: Kidney Week 2013; 5-10 Nov 2013; Atlanta (GA).
    • (2013) Kidney Week
    • Greenbaum, L.A.1    Fila, M.2    Tsimaratos, M.3
  • 19
    • 85081803739 scopus 로고    scopus 로고
    • Efficacy and safety of eculizumab treatment for atypical hemolytic uremic syndrome (aHUS) in pediatric patients: Outcomes from a retrospective study
    • abstract no. 095
    • Lapeyraque A-L, Simonetti G, Vilalta R, et al. Efficacy and safety of eculizumab treatment for atypical hemolytic uremic syndrome (aHUS) in pediatric patients: outcomes from a retrospective study [abstract no. 095]. In: Canadian Society of Nephrology Annual Meeting; 25-30 Apr 2012; St. John's (NL).
    • Canadian Society of Nephrology Annual Meeting; 25-30 Apr 2012; St. John's (NL)
    • Lapeyraque, A.-L.1    Simonetti, G.2    Vilalta, R.3
  • 20
    • 84892583623 scopus 로고    scopus 로고
    • Eculizumab therapy for pediatric patients with atypical hemolytic uremic syndrome: Efficacy and safety outcomes of a retrospective study
    • abstract no. 1155
    • Vilalta R, Al-Akash SI, Davin J, et al. Eculizumab therapy for pediatric patients with atypical hemolytic uremic syndrome: efficacy and safety outcomes of a retrospective study [abstract no. 1155]. Haematologica. 2012;97(Suppl 1):479.
    • (2012) Haematologica , vol.97 , Issue.SUPPL. 1 , pp. 479
    • Vilalta, R.1    Al-Akash, S.I.2    Davin, J.3
  • 21
    • 84883555205 scopus 로고    scopus 로고
    • Eculizumab (ECU) in atypical hemolytic uremic syndrome (aHUS) patients with progressing thrombotic microangiopathy (TMA): 2-year data
    • abstract no. 2084
    • Greenbaum L, Legendre CM, Babu S, et al. Eculizumab (ECU) in atypical hemolytic uremic syndrome (aHUS) patients with progressing thrombotic microangiopathy (TMA): 2-year data [abstract no. 2084]. Blood. 2012;120.
    • (2012) Blood , vol.120
    • Greenbaum, L.1    Legendre, C.M.2    Babu, S.3
  • 22
    • 84883559551 scopus 로고    scopus 로고
    • Eculizumab (ECU) safety and efficacy in atypical hemolytic uremic syndrome (aHUS) patients with long disease duration and chronic kidney disease (CKD): 2-year results
    • abstract no. 985
    • Licht C, Muus P, Legendre CM. Eculizumab (ECU) safety and efficacy in atypical hemolytic uremic syndrome (aHUS) patients with long disease duration and chronic kidney disease (CKD): 2-year results [abstract no. 985]. Blood. 2012;(120).
    • (2012) Blood , Issue.120
    • Licht, C.1    Muus, P.2    Legendre, C.M.3
  • 25
    • 84879121370 scopus 로고    scopus 로고
    • Long-term safety and efficacy of sustained eculizumab treatment in patients with paroxysmal nocturnal haemoglobinuria
    • Hillmen P, Muus P, Roth A, et al. Long-term safety and efficacy of sustained eculizumab treatment in patients with paroxysmal nocturnal haemoglobinuria. Br J Haematol. 2013;162(1):62-73.
    • (2013) Br J Haematol , vol.162 , Issue.1 , pp. 62-73
    • Hillmen, P.1    Muus, P.2    Roth, A.3
  • 26
    • 84877919003 scopus 로고    scopus 로고
    • Eculizumab in AQP4-IgG-positive relapsing neuromyelitis optica spectrum disorders: An open-label pilot study
    • Pittock SJ, Lennon VA, McKeon A, et al. Eculizumab in AQP4-IgG-positive relapsing neuromyelitis optica spectrum disorders: an open-label pilot study. Lancet Neurol. 2013;12(6):554-62.
    • (2013) Lancet Neurol , vol.12 , Issue.6 , pp. 554-562
    • Pittock, S.J.1    Lennon, V.A.2    McKeon, A.3
  • 28
    • 85081807040 scopus 로고    scopus 로고
    • Alexion Pharmaceuticals [ClinicalTrials.gov identifier NCT01522170] US National Institutes of Health. Accessed 10 Feb 2014
    • Alexion Pharmaceuticals. aHUS observational long term follow-up (LTFU) [ClinicalTrials.gov identifier NCT01522170] US National Institutes of Health. Clinical Trials.gov. 2013. http://www.clinicaltrials.gov/ct2/show/NCT01522170. Accessed 10 Feb 2014.
    • (2013) aHUS Observational Long Term Follow-up (LTFU)
  • 29
    • 85081804584 scopus 로고    scopus 로고
    • Alexion Pharmaceuticals. [ClinicalTrials.gov identifier NCT01522183] US National Institutes of Health. Accessed 10 Feb 2014
    • Alexion Pharmaceuticals. Atypical hemolytic-uremic syndrome (aHUS) registry [ClinicalTrials.gov identifier NCT01522183] US National Institutes of Health. Clinical Trials.gov. 2014. http://www.clinicaltrials.gov/ct2/show/ NCT01522183. Accessed 10 Feb 2014.
    • (2014) Atypical Hemolytic-uremic Syndrome (aHUS) Registry


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.