The functional repertoire of rabbit antibodies and antibody discovery via next-generation sequencing

mAbs

Volumn 6, Issue 3, 2014, Pages 628-636

  Kodangattil, Sreekumar ^a   Huard, Christine ^a   Ross, Cindy ^a   Li, Jian ^a   Gao, Huilan ^a   Mascioni, Alessandro ^a   Hodawadekar, Santosh ^a   Naik, Snehal ^a   Min debartolo, Jessica ^a   Visintin, Alberto ^a   Almagro, Juan C ^a  

^a PFIZER INC   (United States)

Author keywords

Antibody gene usage; Antigen binding site; Immunogobulins; Therapeutic antibodies

Indexed keywords

ARGININE; GLYCINE; MONOCLONAL ANTIBODY; RABBIT ANTISERUM; SERINE; TYROSINE; ANTIBODY; COMPLEMENTARITY DETERMINING REGION; IMMUNOGLOBULIN HEAVY CHAIN; IMMUNOGLOBULIN LIGHT CHAIN; IMMUNOGLOBULIN VARIABLE REGION; PEPTIDE;

ALLELE; AMINO ACID COMPOSITION; AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ANIMAL TISSUE; ANTIBODY COMBINING SITE; ANTIBODY DETECTION; ARTICLE; BONE MARROW; COMPLEMENTARITY DETERMINING REGION; GENE MUTATION; GENETIC ENGINEERING; GENETIC PROCEDURES; HYBRIDOMA; LYMPHOCYTE; NEW ZEALAND WHITE (RABBIT); NEXT GENERATION SEQUENCING; NONHUMAN; NORMAL DISTRIBUTION; NUCLEOTIDE SEQUENCE; OPEN READING FRAME; ORYCTOLAGUS CUNICULUS; SPLEEN; ANIMAL; GENETICS; HIGH THROUGHPUT SEQUENCING; HUMAN; IMMUNIZATION; IMMUNOGLOBULIN VARIABLE REGION; IMMUNOLOGY; MOLECULAR GENETICS; MOUSE; MUTATION; PROTEIN ENGINEERING; RABBIT; SEQUENCE HOMOLOGY;

AMINO ACID SEQUENCE; ANIMALS; ANTIBODIES; ANTIBODIES, MONOCLONAL; BONE MARROW; COMPLEMENTARITY DETERMINING REGIONS; HIGH-THROUGHPUT NUCLEOTIDE SEQUENCING; HUMANS; HYBRIDOMAS; IMMUNIZATION; IMMUNOGLOBULIN HEAVY CHAINS; IMMUNOGLOBULIN LIGHT CHAINS; IMMUNOGLOBULIN VARIABLE REGION; MICE; MOLECULAR SEQUENCE DATA; MUTATION; PEPTIDES; PROTEIN ENGINEERING; RABBITS; SEQUENCE HOMOLOGY, AMINO ACID; SPLEEN;

EID: 84899730297     PISSN: 19420862     EISSN: 19420870     Source Type: Journal    
DOI: 10.4161/mabs.28059     Document Type: Article

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