Circulating progenitor cells in rheumatoid arthritis: Association with inflammation and oxidative stress

Scandinavian Journal of Rheumatology

Volumn 43, Issue 3, 2014, Pages 184-193

  Lo Gullo, A ^a   Mandraffino, G ^a   Sardo, M A ^a   D'Ascola, A ^a   Mamone, F ^a   Loddo, S ^a   Alibrandi, A ^a   Imbalzano, E ^a   Mandraffino, R ^a   Mormina, E ^a   Saitta, C ^a   Lo Gullo, R ^a   David, A ^a   Saitta, A ^a  

^a UNIVERSITY OF MESSINA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MARKER; C REACTIVE PROTEIN; CATALASE; CD34 ANTIGEN; FIBRINOGEN; GLUTATHIONE PEROXIDASE; MANGANESE SUPEROXIDE DISMUTASE; MESSENGER RNA; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 2;

ADULT; ARTERIAL STIFFNESS; ARTERIAL WALL THICKNESS; ARTICLE; ATHEROSCLEROSIS; AUGMENTATION INDEX; BLOOD VESSEL PARAMETERS; CELL COUNT; CIRCULATING PROGENITOR CELL; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE ASSOCIATION; ERYTHROCYTE SEDIMENTATION RATE; FEMALE; HUMAN; HUMAN CELL; INFLAMMATION; MALE; MIDDLE AGED; OXIDATION REDUCTION STATE; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PULSE WAVE; RHEUMATOID ARTHRITIS; STEM CELL; VASCULAR LESION;

AGED; ANGIOGRAPHY; ANTIGENS, CD34; ARTHRITIS, RHEUMATOID; ATHEROSCLEROSIS; BLOOD FLOW VELOCITY; C-REACTIVE PROTEIN; CAROTID INTIMA-MEDIA THICKNESS; CASE-CONTROL STUDIES; CATALASE; CAUSALITY; COMORBIDITY; DISEASE PROGRESSION; FEMALE; HUMANS; INFLAMMATION; INFLAMMATION MEDIATORS; LINEAR MODELS; MALE; MIDDLE AGED; MULTIVARIATE ANALYSIS; OXIDATIVE STRESS; PREDICTIVE VALUE OF TESTS; PROGNOSIS; REACTIVE OXYGEN SPECIES; SEVERITY OF ILLNESS INDEX; STEM CELLS; SUPEROXIDE DISMUTASE; ULTRASONOGRAPHY, DOPPLER; VASCULAR STIFFNESS;

EID: 84899729651     PISSN: 03009742     EISSN: 15027732     Source Type: Journal    
DOI: 10.3109/03009742.2013.836564     Document Type: Article

References (57)

1. Steinmetz M, Nickenig G, Werner N. Endothelial-regenerating cells: An expanding universe. Hypertension 2010;55:593-9
2. Pesce M, Burba I, Gambini E, Prandi F, Pompilio G, Capogrossi MC. Endothelial and cardiac progenitors: Boosting, conditioning and (re)programming for cardiovascular repair. Pharmacol Ther 2011;129:50-61
3. Hristov M, Weber C. Endothelial progenitor cells in vascular repair and remodeling. Pharmacol Res 2008;58:148-51
4. GrahamI, Atar D, Borch-Johnsen K, Boysen G, BurellG, Cifkova R, et al. European guidelines on cardiovascular disease prevention in clinical practice: Full text. Fourth Joint Task Force of the European Society of Cardiology and other societies on cardiovascular disease prevention in clinical practice (constituted by representatives of nine societies and by invited experts). Eur J Cardiovasc Prev Rehabil 2007;14(Suppl 2):S1-113
5. de Boer HC, Hovens MM, van Oeveren-Rietdijk AM, Snoep JD, de Koning EJ, Tamsma JT, et al. Human CD34/KDR cells are generated from circulating CD34 cells after immobilization on activated platelets. Arterioscler Thromb Vasc Biol 2011;31:408-15
6. Fadini GP, de Kreutzenberg S, Agostini C, Boscaro E, Tiengo A, Dimmeler S, et al. Low CD34 cell count and metabolic syndrome synergistically increase the risk of adverse outcomes. Atherosclerosis 2009;207:213-19
7. Werner N, Kosiol S, Schiegl T, Ahlers P, Walenta K, Link A, et al. Circulating endothelial progenitor cells and cardiovascular outcomes. N Engl J Med 2005;353:999-1007
8. Laragione T, Shah A, Gulko PS. The vitamin D receptor regulates rheumatoid arthritis synovial fibroblast invasion and morphology. Mol Med 2012;18:194-200
9. Akhavani MA, Larsen H, Paleolog E. Circulating endothelial progenitor cells as a link between synovial vascularity and cardiovascular mortality in rheumatoid arthritis. Scand J Rheumatol 2007;36:83-90
10. Sattar N, McCarey DW, Capell H, McInnes IB. Explaining how high-grade systemic inflammation accelerates vascular risk in rheumatoid arthritis. Circulation 2003;108:2957-63
11. Koivuniemi R, Paimela L, Suomalainen R, Leirisalo-Repo M. Cardiovascular diseases in patients with rheumatoid arthritis. Scand J Rheumatol 2013;42:131-5
12. Garcia-Bermudez M, Lopez-Mejias R, Gonzalez-Juanatey C, Castaneda S, Miranda-Filloy JA, Blanco R, et al. Association of the methionine sulfoxide reductase A rs10903323 gene polymorphism with cardiovascular disease in patients with rheumatoid arthritis. Scand J Rheumatol 2012;41:350-3
13. Pasceri V, Yeh ET. A tale of two diseases: Atherosclerosis and rheumatoid arthritis. Circulation 1999;100:2124-6
14. Ku IA, Imboden JB, Hsue PY, Ganz P. Rheumatoid arthritis: Model of systemic inflammation Driving atherosclerosis. Circ J 2009;73:977-85
15. E XQ, Meng HX, Cao Y, Zhang SQ, Bi ZG, Yamakawa M. Distribution of regulatory T cells and interaction with dendritic cells in the synovium of rheumatoid arthritis. Scand J Rheumatol 2012;41:413-20
16. Fan LY, He DY, Wang Q, Zong M, Zhang H, Yang L, et al. Citrullinated vimentin stimulates proliferation, pro-inflammatory cytokine secretion, and PADI4 and RANKL expression of fibroblast-like synoviocytes in rheumatoid arthritis. Scand J Rheumatol 2012;41:354-8
17. Fox DA, Gizinski A, Morgan R, Lundy SK. Cell-cell interactions in rheumatoid arthritis synovium. Rheum Dis Clin North Am 2010;36:311-23
18. Silverman MD, Haas CS, Rad AM, Arbab AS, Koch AE. The role of vascular cell adhesion molecule 1/very late activation antigen 4 in endothelial progenitor cell recruitment to rheumatoid arthritis synovium. Arthritis Rheum 2007;56:1817-26
19. Herbrig K, Haensel S, Oelschlaegel U, Pistrosch F, Foerster S, Passauer J. Endothelial dysfunction in patients with rheumatoid arthritis is associated with a reduced number and impaired function of endothelial progenitor cells. Ann Rheum Dis 2006;65:157-63
20. Grisar J, Aletaha D, Steiner CW, Kapral T, Steiner S, Seidinger D, et al. Depletion of endothelial progenitor cells in the peripheral blood of patients with rheumatoid arthritis. Circulation 2005; 111:204-11
21. Cai H, Harrison DG. Endothelial dysfunction in cardiovascular diseases: The role of oxidant stress. Circ Res 2000;87:840-4
22. Hitchon CA, El-Gabalawy HS. Oxidation in rheumatoid arthritis. Arthritis Res Ther 2004;6:265-78
23. PesceM,Orlandi A, IachininotoMG, Straino S, Torella AR, RizzutiV, et al. Myoendothelial differentiation of human umbilical cord bloodderived stem cells in ischemic limb tissues. Circ Res 2003;93:e51-62
24. Dernbach E, Urbich C, Brandes RP, Hofmann WK, Zeiher AM, Dimmeler S. Antioxidative stress-Associated genes in circulating progenitor cells: Evidence for enhanced resistance against oxidative stress. Blood 2004;104:3591-7
25. Fan J, Cai H, Tan WS. Role of the plasma membrane ROSgenerating NADPH oxidase in CD34 progenitor cells preservation by hypoxia. J Biotechnol 2007;130:455-62
26. Ushio-Fukai M, Tang Y, Fukai T, Dikalov SI, Ma Y, Fujimoto M, et al. Novel role of gp91(phox)-containing NAD(P)H oxidase in vascular endothelial growth factor-induced signaling and angiogenesis. Circ Res 2002;91:1160-7
27. Hwang J, Ing MH, Salazar A, Lassegue B, GriendLing K, Navab M, et al. Pulsatile versus oscillatory shear stress regulates NADPH oxidase subunit expression: Implication for native LDL oxidation. Circ Res 2003;93:1225-32
28. Mollnau H, Wendt M, Szocs K, Lassegue B, Schulz E, Oelze M, et al. Effects of angiotensin II infusion on the expression and function of NAD(P)H oxidase and components of nitric oxide/ cGMP signaling. Circ Res 2002;90:E58-65
29. Touyz RM. Reactive oxygen species, vascular oxidative stress, and redox signaling in hypertension: What is the clinical significance?. Hypertension 2004;44:248-52
30. Mandraffino G, SardoMA, Riggio S, Loddo S, Imbalzano E,Alibrandi A, et al. Circulating progenitor cells are increased in newly diagnosed untreated hypertensive patients with arterial stiffening but normal carotid intima-media thickness. Hypertens Res 2011;34:876-83
31. Noble M, Smith J, Power J, Mayer-Proschel M. Redox state as a central modulator of precursor cell function. Ann N Y Acad Sci 2003;991:251-71
32. Rossig L, Urbich C, Dimmeler S. Endothelial progenitor cells at work: Not mature yet, but already stress-resistant. Arterioscler Thromb Vasc Biol 2004;24:1977-9
33. von Zglinicki T. Oxidative stress shortens telomeres. Trends Biochem Sci 2002;27:339-44
34. Mandraffino G, Sardo MA, Riggio S, DAscola A, Loddo S, Alibrandi A, et al. Smoke exposure and circulating progenitor cells: Evidence for modulation of antioxidant enzymes and cell count. Clin Biochem 2010;43:1436-42
35. Imanishi T, Hano T, Nishio I. Angiotensin II accelerates endothelial progenitor cell senescence through induction of oxidative stress. J Hypertens 2005;23:97-104
36. Arnett FC, Edworthy SM, Bloch DA, McShane DJ, Fries JF, Cooper NS, et al. The American Rheumatism Association 1987 revised criteria for the classification of rheumatoid arthritis. Arthritis Rheum 1988;31:315-24
37. Fransen J, van Riel PL. The Disease Activity Score and the EULAR response criteria. Clin Exp Rheumatol 2005;23: S93-9
38. LeBel CP, Ischiropoulos H, Bondy SC. Evaluation of the probe 20,70-dichlorofluorescin as an indicator of reactive oxygen species formation and oxidative stress. Chem Res Toxicol 1992;5:227-31
39. Wang YX, Fitch RM. Vascular stiffness: Measurements, mechanisms and implications. Curr Vasc Pharmacol 2004;2:379-84
40. Provan SA, Angel K, Semb AG, Mowinckel P, Agewall S, Atar D, et al. Early prediction of increased arterial stiffness in patients with chronic inflammation: A 15-year followup study of 108 patients with rheumatoid arthritis. J Rheumatol 2011;38:606-12
41. Riggio S, Mandraffino G, Sardo MA, Iudicello R, Camarda N, Imbalzano E, et al. Pulse wave velocity and augmentation index, but not intima-media thickness, are early indicators of vascular damage in hypercholesterolemic children. Eur J Clin Invest 2010;40:250-7
42. Ludbrook J, DudLey H. Why permutation tests are superior to t and F tests in biomedical research. American Statistician 1998;52:127-32
43. Pesarin F, Salmaso L. Permutation tests for complex data: Theory, applications and software. Chichester,UK: John Wiley&Sons, 2010
44. Pesarin F, editor. Multivariate permutation tests with applications in biostatistics. Chichester: Wiley, 2001
45. Mancia G, De Backer G, Dominiczak A, Cifkova R, Fagard R, Germano G, et al. 2007 Guidelines for the management of arterial hypertension: The Task Force for the Management of Arterial Hypertension of the European Society of Hypertension (ESH) and of the European Society of Cardiology (ESC). J Hypertens 2007;25:1105-87
46. Ross R. The pathogenesis of atherosclerosis: A perspective for the 1990s. Nature 1993;362:801-9
47. Libby P. Role of inflammation in atherosclerosis associated with rheumatoid arthritis. Am J Med 2008;121:S21-31
48. Kaptoge S, Di Angelantonio E, Lowe G, Pepys MB, Thompson SG, Collins R, et al. C-reactive protein concentration and risk of coronary heart disease, stroke, and mortality: An individual participant meta-Analysis. Lancet 2010;375:132-40
49. He T, Peterson TE, Holmuhamedov EL, Terzic A, CapliceNM,Oberley LW, et al. Human endothelial progenitor cells tolerate oxidative stress due to intrinsically high expression of manganese superoxide dismutase. Arterioscler Thromb Vasc Biol 2004;24: 2021-7
50. Droge W. Free radicals in the physiological control of cell function. Physiol Rev 2002;82:47-95
51. Piccoli C,DAprile A, Ripoli M, Scrima R, Lecce L, Boffoli D, et al. Bone-marrow derived hematopoietic stem/progenitor cells express multiple isoforms of NADPH oxidase and produce constitutively reactive oxygen species. Biochem Biophys Res Commun 2007;353:965-72
52. Vafa O, Wade M, Kern S, Beeche M, Pandita TK, Hampton GM, et al. c-Myc can induce DNA damage, increase reactive oxygen species, and mitigate p53 function: A mechanism for oncogene-induced genetic instability. Mol Cell 2002;9: 1031-44
53. Vasa M, Fichtlscherer S, Aicher A, AdLer K, Urbich C, Martin H, et al. Number and migratory activity of circulating endothelial progenitor cells inversely correlate with risk factors for coronary artery disease. Circ Res 2001;89:E1-7
54. Tousoulis D, Andreou I, Antoniades C, Tentolouris C, Stefanadis C. Role of inflammation and oxidative stress in endothelial progenitor cell function and mobilization: Therapeutic implications for cardiovascular diseases. Atherosclerosis 2008;201: 236-47
55. Galasso G, Schiekofer S, Sato K, Shibata R, Handy DE, Ouchi N, et al. Impaired angiogenesis in glutathione peroxidase-1-deficient mice is associated with endothelial progenitor cell dysfunction. Circ Res 2006;98:254-61
56. Verma S, Kuliszewski MA, Li SH, Szmitko PE, Zucco L, Wang CH, et al. C-reactive protein attenuates endothelial progenitor cell survival, differentiation, and function: Further evidence of a mechanistic link between C-reactive protein and cardiovascular disease. Circulation 2004;109:2058-67
57. Fujii H, Li SH, Szmitko PE, Fedak PW, Verma S. C-reactive protein alters antioxidant defenses and promotes apoptosis in endothelial progenitor cells. Arterioscler Thromb Vasc Biol 2006;26:2476-82.