Gender differences in the relationships between lean body mass, fat mass and peak bone mass in young adults

Osteoporosis International

Volumn 25, Issue 5, 2014, Pages 1563-1570

  Zhu, K ^a,b   Briffa, K ^c   Smith, A ^c   Mountain, J ^d   Briggs, A M ^e   Lye, S ^f   Pennell, C ^g   Straker, L ^c   Walsh, J P ^a,b  

^a SIR CHARLES GAIRDNER HOSPITAL   (Australia)

^b UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

^c CURTIN UNIVERSITY   (Australia)

^d UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

^e CURTIN UNIVERSITY   (Australia)

^f MOUNT SINAI HOSPITAL   (Canada)

^g UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

Author keywords

Fat mass; Lean body mass; Peak bone mass; Raine Study; Trunk to limb fat mass ratio; Young adults

Indexed keywords

ADULT; ARTICLE; BODY COMPOSITION; BODY HEIGHT; BODY SIZE; BONE DENSITY; BONE MASS; DUAL ENERGY X RAY ABSORPTIOMETRY; FAT MASS; FEMALE; HUMAN; HUMAN EXPERIMENT; INTRAABDOMINAL FAT; LEAN BODY WEIGHT; MALE; PRIORITY JOURNAL; SEX DIFFERENCE; YOUNG ADULT; ADIPOSE TISSUE; ANATOMY AND HISTOLOGY; ANTHROPOMETRY; BODY MASS; BODY WEIGHT; PATHOLOGY; PHOTON ABSORPTIOMETRY; PHYSIOLOGY; PROCEDURES; SEXUAL DEVELOPMENT;

ABSORPTIOMETRY, PHOTON; ADIPOSE TISSUE; ANTHROPOMETRY; BODY COMPOSITION; BODY HEIGHT; BODY MASS INDEX; BONE DENSITY; FEMALE; HUMANS; MALE; SEX CHARACTERISTICS; THINNESS; YOUNG ADULT;

EID: 84899655972     PISSN: 0937941X     EISSN: 14332965     Source Type: Journal    
DOI: 10.1007/s00198-014-2665-x     Document Type: Article

References (34)

1. Khosla S, Atkinson EJ, Riggs BL, Melton LJ III (1996) Relationship between body composition and bone mass in women. J Bone Miner Res 11:857-863
2. Bogl LH, Latvala A, Kaprio J, Sovijarvi O, Rissanen A, Pietilainen KH (2011) An investigation into the relationship between soft tissue body composition and bone mineral density in a young adult twin sample. J Bone Miner Res 26:79-87
3. Wang MC, Bachrach LK, Van Loan M, Hudes M, Flegal KM, Crawford PB (2005) The relative contributions of lean tissue mass and fat mass to bone density in young women. Bone 37:474-481
4. Sayers A, Tobias JH (2010) Fat mass exerts a greater effect on cortical bone mass in girls than boys. J Clin Endocrinol Metab 95:699-706
5. Janicka A, Wren TA, Sanchez MM, Dorey F, Kim PS, Mittelman SD, Gilsanz V (2007) Fat mass is not beneficial to bone in adolescents and young adults. J Clin Endocrinol Metab 92:143-147
6. Baxter-Jones AD, Eisenmann JC, Mirwald RL, Faulkner RA, Bailey DA (2008) The influence of physical activity on lean mass accrual during adolescence: a longitudinal analysis. J Appl Physiol 105:734-741
7. Lu H, Fu X, Ma X, Wu Z, He W, Wang Z, Allison DB, Heymsfield SB, Zhu S (2011) Relationships of percent body fat and percent trunk fat with bone mineral density among Chinese, black, and white subjects. Osteoporos Int 22:3029-3035
8. Taes YE, Lapauw B, Vanbillemont G, Bogaert V, De Bacquer D, Zmierczak H, Goemaere S, Kaufman JM (2009) Fat mass is negatively associated with cortical bone size in young healthy male siblings. J Clin Endocrinol Metab 94:2325-2331
9. Baker JF, Davis M, Alexander R, Zemel BS, Mostoufi-Moab S, Shults J, Sulik M, Schiferl DJ, Leonard MB (2013) Associations between body composition and bone density and structure in men and women across the adult age spectrum. Bone 53:34-41
10. Hamrick MW, Ferrari SL (2008) Leptin and the sympathetic connection of fat to bone. Osteoporos Int 19:905-912
11. Reid IR (2010) Fat and bone. Arch Biochem Biophys 503:20-27
12. Braun T, Schett G (2012) Pathways for bone loss in inflammatory disease. Curr Osteoporos Rep 10:101-108
13. Heaney RP, Abrams S, Dawson-Hughes B, Looker A, Marcus R, Matkovic V, Weaver C (2000) Peak bone mass. Osteoporos Int 11:985-1009
14. WHO (March 2011) Obesity and overweight. Fact sheet N°311. World Health Organization
15. Zagarins SE, Ronnenberg AG, Gehlbach SH, Lin R, Bertone-Johnson ER (2010) The association of lean mass and fat mass with peak bone mass in young premenopausal women. J Clin Densitom 13:392-398
16. Kirchengast S (2010) Gender differences in body composition from childhood to old age: an evolutionary point of view. Journal of Life Science 2:1-10
17. Makovey J, Naganathan V, Sambrook P (2005) Gender differences in relationships between body composition components, their distribution and bone mineral density: a cross-sectional opposite sex twin study. Osteoporos Int 16:1495-1505
18. Reid IR, Plank LD, Evans MC (1992) Fat mass is an important determinant of whole body bone density in premenopausal women but not in men. J Clin Endocrinol Metab 75:779-782
19. Russell M, Mendes N, Miller KK, Rosen CJ, Lee H, Klibanski A, Misra M (2010) Visceral fat is a negative predictor of bone density measures in obese adolescent girls. J Clin Endocrinol Metab 95:1247-1255
20. Ackerman KE, Davis B, Jacoby L, Misra M (2011) DXA surrogates for visceral fat are inversely associated with bone density measures in adolescent athletes with menstrual dysfunction. J Pediatr Endocrinol Metab 24:497-504
21. Gilsanz V, Chalfant J, Mo AO, Lee DC, Dorey FJ, Mittelman SD (2009) Reciprocal relations of subcutaneous and visceral fat to bone structure and strength. J Clin Endocrinol Metab 94:3387-3393
22. Baxter-Jones AD, Faulkner RA, Forwood MR, Mirwald RL, Bailey DA (2011) Bone mineral accrual from 8 to 30 years of age: an estimation of peak bone mass. J Bone Miner Res 26:1729-1739
23. Newnham JP, Evans SF, Michael CA, Stanley FJ, Landau LI (1993) Effects of frequent ultrasound during pregnancy: a randomised controlled trial. Lancet 342:887-891
24. Robinson M, Oddy WH, McLean NJ, Jacoby P, Pennell CE, de Klerk NH, Zubrick SR, Stanley FJ, Newnham JP (2010) Low-moderate prenatal alcohol exposure and risk to child behavioural development: a prospective cohort study. BJOG 117:1139-1150
25. Savgan-Gurol E, Bredella M, Russell M, Mendes N, Klibanski A, Misra M (2010) Waist to hip ratio and trunk to extremity fat (DXA) are better surrogates for IMCL and for visceral fat respectively than for subcutaneous fat in adolescent girls. Nutr Metab (Lond) 7:86
26. Kleinbaum DG, Kupper LL, Muller KE, Nizam A (1998) Applied regression analysis and other multivariable methods. Duxbury Press, Pacific Grove
27. De Laet C, Kanis JA, Oden A et al (2005) Body mass index as a predictor of fracture risk: a meta-analysis. Osteoporos Int 16:1330-1338
28. Choi HS, Kim KJ, Kim KM, Hur NW, Rhee Y, Han DS, Lee EJ, Lim SK (2010) Relationship between visceral adiposity and bone mineral density in Korean adults. Calcif Tissue Int 87:218-225
29. Bouxsein M (2011) Biomechanics of age-related fractures. In: Marcus R, Feldman D, Kelsey J (eds) Osteoporosis, II edn. Academic, San Diego, pp 509-534
30. Pou KM, Massaro JM, Hoffmann U et al (2007) Visceral and subcutaneous adipose tissue volumes are cross-sectionally related to markers of inflammation and oxidative stress: the Framingham heart study. Circulation 116:1234-1241
31. Cartier A, Lemieux I, Almeras N, Tremblay A, Bergeron J, Despres JP (2008) Visceral obesity and plasma glucose-insulin homeostasis: contributions of interleukin-6 and tumor necrosis factor-alpha in men. J Clin Endocrinol Metab 93:1931-1938
32. Hsu YH, Venners SA, Terwedow HA et al (2006) Relation of body composition, fat mass, and serum lipids to osteoporotic fractures and bone mineral density in Chinese men and women. Am J Clin Nutr 83:146-154
33. Dimitri P, Bishop N, Walsh JS, Eastell R (2012) Obesity is a risk factor for fracture in children but is protective against fracture in adults: a paradox. Bone 50:457-466
34. Schott AM, Cormier C, Hans D et al (1998) How hip and whole-body bone mineral density predict hip fracture in elderly women: the EPIDOS prospective study. Osteoporos Int 8:247-254