Relationship between visceral adiposity and bone mineral density in korean adults

Calcified Tissue International

Volumn 87, Issue 3, 2010, Pages 218-225

  Choi, Han Seok ^a,b   Kim, Kwang Joon ^b   Kim, Kyoung Min ^b   Hur, Nam Wook ^b   Rhee, Yumie ^b   Han, Dae Suk ^b   Lee, Eun Jig ^b   Lim, Sung Kil ^b  

^a Dongguk University Ilsan Hospital   (South Korea)

^b Yonsei University College of Medicine   (South Korea)

Author keywords

Bone mineral density; Metabolic factor; Obesity; Subcutaneous adiposity; Visceral adiposity

Indexed keywords

HIGH DENSITY LIPOPROTEIN CHOLESTEROL; LOW DENSITY LIPOPROTEIN CHOLESTEROL;

ABDOMINAL OBESITY; ADULT; AGED; ARTICLE; BODY COMPOSITION; BODY FAT DISTRIBUTION; BONE DENSITY; BONE METABOLISM; COMPUTER ASSISTED TOMOGRAPHY; CONTROLLED STUDY; CROSS-SECTIONAL STUDY; DISEASE ASSOCIATION; FEMALE; FEMUR NECK; HIP; HUMAN; INTRAABDOMINAL FAT; KOREA; LUMBAR SPINE; MALE; PRIORITY JOURNAL; SEX DIFFERENCE; SUBCUTANEOUS FAT;

ADIPOSITY; ADULT; AGED; AGED, 80 AND OVER; BODY COMPOSITION; BONE DENSITY; CHOLESTEROL, HDL; CHOLESTEROL, LDL; CROSS-SECTIONAL STUDIES; FEMALE; HUMANS; MALE; MIDDLE AGED; REPUBLIC OF KOREA; SUBCUTANEOUS FAT; VISCERA;

EID: 77956183276     PISSN: 0171967X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00223-010-9398-4     Document Type: Article

References (54)

1. GM Wardlaw 1996 Putting body weight and osteoporosis into perspective Am J Clin Nutr 63 433S 436S 8615336
2. SL Edelstein E Barrett-Connor 1993 Relation between body size and bone mineral density in elderly men and women Am J Epidemiol 138 160 169 8356959
3. T Kameda H Mano T Yuasa Y Mori K Miyazawa M Shiokawa Y Nakamaru E Hiroi K Hiura A Kameda NN Yang Y Hakeda M Kumegawa 1997 Estrogen inhibits bone resorption by directly inducing apoptosis of the bone-resorbing osteoclasts J Exp Med 186 489 495 10.1084/jem.186.4.489 9254647
4. YH Hsu SA Venners HA Terwedow Y Feng T Niu Z Li N Laird JD Brain SR Cummings ML Bouxsein CJ Rosen X Xu 2006 Relation of body composition, fat mass, and serum lipids to osteoporotic fractures and bone mineral density in Chinese men and women Am J Clin Nutr 83 146 154 16400063
5. LJ Zhao YJ Liu PY Liu J Hamilton RR Recker HW Deng 2007 Relationship of obesity with osteoporosis J Clin Endocrinol Metab 92 1640 1646 10.1210/jc.2006-0572 17299077
6. LJ Zhao H Jiang CJ Papasian D Maulik B Drees J Hamilton HW Deng 2008 Correlation of obesity and osteoporosis: effect of fat mass on the determination of osteoporosis J Bone Miner Res 23 17 29 10.1359/jbmr.070813 17784844
7. BL Wajchenberg 2000 Subcutaneous and visceral adipose tissue: their relation to the metabolic syndrome Endocr Rev 21 697 738 10.1210/er.21.6.697 11133069
8. CJ Heiss CF Sanborn DL Nichols SL Bonnick BB Alford 1995 Associations of body fat distribution, circulating sex hormones, and bone density in postmenopausal women J Clin Endocrinol Metab 80 1591 1596 10.1210/jc.80.5.1591 7745005
9. R Blaauw EC Albertse S Hough 1996 Body fat distribution as a risk factor for osteoporosis S Afr Med J 86 1081 1084 8888774
10. T Douchi S Yamamoto T Oki K Maruta R Kuwahata Y Nagata 2000 Relationship between body fat distribution and bone mineral density in premenopausal Japanese women Obstet Gynecol 95 722 725 10.1016/S0029-7844(99)00663-8 10775737
11. EA Jankowska E Rogucka M Medras 2001 Are general obesity and visceral adiposity in men linked to reduced bone mineral content resulting from normal ageing? A population-based study Andrologia 33 384 389 10.1046/j.1439-0272.2001. 00469.x 11736801
12. L Warming P Ravn C Christiansen 2003 Visceral fat is more important than peripheral fat for endometrial thickness and bone mass in healthy postmenopausal women Am J Obstet Gynecol 188 349 353 10.1067/mob.2003.93 12592238
13. Bonora E, Micciolo R, Ghiatas AA, Lancaster JL, Alyassin A, Muggeo M, DeFronzo RA (1995) Is it possible to derive a reliable estimate of human visceral and subcutaneous abdominal adipose tissue from simple anthropometric measurements? Metabolism 44:1617-1625
14. JL Clasey C Bouchard CD Teates JE Riblett MO Thorner ML Hartman A Weltman 1999 The use of anthropometric and dual-energy X-ray absorptiometry (DXA) measures to estimate total abdominal and abdominal visceral fat in men and women Obes Res 7 256 264 10348496
15. MB Snijder M Visser JM Dekker JC Seidell T Fuerst F Tylavsky J Cauley T Lang M Nevitt TB Harris 2002 The prediction of visceral fat by dual-energy X-ray absorptiometry in the elderly: a comparison with computed tomography and anthropometry Int J Obes Relat Metab Disord 26 984 993 10.1038/sj.ijo.0801968 12080454
16. HC Lukaski WW Bolonchuk CB Hall WA Siders 1986 Validation of tetrapolar bioelectrical impedance method to assess human body composition J Appl Physiol 60 1327 1332 3700310
17. AC Maurin PM Chavassieux L Frappart PD Delmas CM Serre PJ Meunier 2000 Influence of mature adipocytes on osteoblast proliferation in human primary cocultures Bone 26 485 489 10.1016/S8756-3282(00)00252-0 10773588
18. T Akune S Ohba S Kamekura M Yamaguchi UI Chung N Kubota Y Terauchi Y Harada Y Azuma K Nakamura T Kadowaki H Kawaguchi 2004 PPARgamma insufficiency enhances osteogenesis through osteoblast formation from bone marrow progenitors J Clin Invest 113 846 855 15067317
19. V Krishnan HU Bryant OA Macdougald 2006 Regulation of bone mass by Wnt signaling J Clin Invest 116 1202 1209 10.1172/JCI28551 16670761
20. T Yamaguchi T Sugimoto S Yano M Yamauchi H Sowa Q Chen K Chihara 2002 Plasma lipids and osteoporosis in postmenopausal women Endocr J 49 211 217 10.1507/endocrj.49.211 12081241
21. F Parhami AD Morrow J Balucan N Leitinger AD Watson Y Tintut JA Berliner LL Demer 1997 Lipid oxidation products have opposite effects on calcifying vascular cell and bone cell differentiation. A possible explanation for the paradox of arterial calcification in osteoporotic patients Arterioscler Thromb Vasc Biol 17 680 687 9108780
22. D Vashishth GJ Gibson JI Khoury MB Schaffler J Kimura DP Fyhrie 2001 Influence of nonenzymatic glycation on biomechanical properties of cortical bone Bone 28 195 201 10.1016/S8756-3282(00)00434-8 11182378
23. D von Muhlen S Safii SK Jassal J Svartberg E Barrett-Connor 2007 Associations between the metabolic syndrome and bone health in older men and women: the Rancho Bernardo Study Osteoporos Int 18 1337 1344 10.1007/s00198-007-0385-1
24. MC Zillikens AG Uitterlinden JP van Leeuwen AL Berends P Henneman KW van Dijk BA Oostra CM van Duijn HA Pols F Rivadeneira 2010 The role of body mass index, insulin, and adiponectin in the relation between fat distribution and bone mineral density Calcif Tissue Int 86 116 125 10.1007/s00223-009-9319-6 19957167
25. M Russell N Mendes KK Miller CJ Rosen H Lee A Klibanski M Misra 2010 Visceral fat is a negative predictor of bone density measures in obese adolescent girls J Clin Endocrinol Metab 95 1247 1255 10.1210/jc.2009-1475 20080853
26. S Adami V Braga M Zamboni D Gatti M Rossini J Bakri E Battaglia 2004 Relationship between lipids and bone mass in 2 cohorts of healthy women and men Calcif Tissue Int 74 136 142 10.1007/s00223-003-0050-4 14668965
27. DI Feig DH Kang RJ Johnson 2008 Uric acid and cardiovascular risk N Engl J Med 359 1811 1821 10.1056/NEJMra0800885 18946066
28. J Fang MH Alderman 2000 Serum uric acid and cardiovascular mortality the NHANES I epidemiologic follow-up study, 1971-1992. National Health and Nutrition Examination Survey JAMA 283 2404 2410 10.1001/jama.283.18.2404 10815083
29. Nieto FJ, Iribarren C, Gross MD, Comstock GW, Cutler RG (2000) Uric acid and serum antioxidant capacity: a reaction to atherosclerosis? Atherosclerosis 148:131-139
30. PG McTernan LA Anderson AJ Anwar MC Eggo J Crocker AH Barnett PM Stewart S Kumar 2002 Glucocorticoid regulation of p450 aromatase activity in human adipose tissue: gender and site differences J Clin Endocrinol Metab 87 1327 1336 10.1210/jc.87.3.1327 11889205
31. H Zhao Z Tian J Hao B Chen 2005 Extragonadal aromatization increases with time after ovariectomy in rats Reprod Biol Endocrinol 3 6 10.1186/1477-7827-3-6 15661083
32. I Chiodini L Tauchmanova M Torlontano C Battista G Guglielmi M Cammisa A Colao V Carnevale R Rossi S Di Lembo V Trischitta A Scillitani 2002 Bone involvement in eugonadal male patients with adrenal incidentaloma and subclinical hypercortisolism J Clin Endocrinol Metab 87 5491 5494 10.1210/jc.2002-020399 12466342
33. PM Peeke GP Chrousos 1995 Hypercortisolism and obesity Ann N Y Acad Sci 771 665 676 10.1111/j.1749-6632.1995.tb44719.x 8597440
34. E Hypponen BJ Boucher DJ Berry C Power 2008 25-Hydroxyvitamin D, IGF-1, and metabolic syndrome at 45 years of age: a cross-sectional study in the 1958 British birth cohort Diabetes 57 298 305 10.2337/db07-1122 18003755
35. L Lu Z Yu A Pan FB Hu OH Franco H Li X Li X Yang Y Chen X Lin 2009 Plasma 25-hydroxyvitamin D concentration and metabolic syndrome among middle-aged and elderly Chinese individuals Diabetes Care 32 1278 1283 10.2337/dc09-0209 19366976
36. P Ducy M Amling S Takeda M Priemel AF Schilling FT Beil J Shen C Vinson JM Rueger G Karsenty 2000 Leptin inhibits bone formation through a hypothalamic relay: a central control of bone mass Cell 100 197 207 10.1016/S0092-8674(00) 81558-5 10660043
37. S Takeda F Elefteriou R Levasseur X Liu L Zhao KL Parker D Armstrong P Ducy G Karsenty 2002 Leptin regulates bone formation via the sympathetic nervous system Cell 111 305 317 10.1016/S0092-8674(02)01049-8 12419242
38. B Burguera LC Hofbauer T Thomas F Gori GL Evans S Khosla BL Riggs RT Turner 2001 Leptin reduces ovariectomy-induced bone loss in rats Endocrinology 142 3546 3553 10.1210/en.142.8.3546 11459801
39. Y Shinoda M Yamaguchi N Ogata T Akune N Kubota T Yamauchi Y Terauchi T Kadowaki Y Takeuchi S Fukumoto T Ikeda K Hoshi UI Chung K Nakamura H Kawaguchi 2006 Regulation of bone formation by adiponectin through autocrine/paracrine and endocrine pathways J Cell Biochem 99 196 208 10.1002/jcb.20890 16598753
40. M Yamauchi T Sugimoto T Yamaguchi D Nakaoka M Kanzawa S Yano R Ozuru T Sugishita K Chihara 2001 Plasma leptin concentrations are associated with bone mineral density and the presence of vertebral fractures in postmenopausal women Clin Endocrinol (Oxf) 55 341 347 10.1046/j.1365-2265.2001.01361.x
41. JA Pasco MJ Henry MA Kotowicz GR Collier MJ Ball AM Ugoni GC Nicholson 2001 Serum leptin levels are associated with bone mass in nonobese women J Clin Endocrinol Metab 86 1884 1887 10.1210/jc.86.5.1884 11344177
42. L Lenchik TC Register FC Hsu K Lohman BJ Nicklas BI Freedman CD Langefeld JJ Carr DW Bowden 2003 Adiponectin as a novel determinant of bone mineral density and visceral fat Bone 33 646 651 10.1016/S8756-3282(03)00237-0 14555270
43. MR Araneta D von Mühlen E Barrett-Connor 2009 Sex differences in the association between adiponectin and BMD, bone loss, and fractures: the Rancho Bernardo study J Bone Miner Res 24 2016 2022 10.1359/jbmr.090519 19453256
44. M Blum SS Harris A Must EN Naumova SM Phillips WM Rand B Dawson-Hughes 2003 Leptin, body composition and bone mineral density in premenopausal women Calcif Tissue Int 73 27 32 10.1007/s00223-002-1019-4 14506951
45. MD Kontogianni UG Dafni JG Routsias FN Skopouli 2004 Blood leptin and adiponectin as possible mediators of the relation between fat mass and BMD in perimenopausal women J Bone Miner Res 19 546 551 10.1359/JBMR.040107 15005840
46. KW Oh WY Lee EJ Rhee KH Baek KH Yoon MI Kang EJ Yun CY Park SH Ihm MG Choi HJ Yoo SW Park 2005 The relationship between serum resistin, leptin, adiponectin, ghrelin levels and bone mineral density in middle-aged men Clin Endocrinol (Oxf) 63 131 138 10.1111/j.1365-2265.2005.02312.x
47. S Gonnelli C Caffarelli K Del Santo A Cadirni C Guerriero B Lucani B Franci R Nuti 2008 The relationship of ghrelin and adiponectin with bone mineral density and bone turnover markers in elderly men Calcif Tissue Int 83 55 60 10.1007/s00223-008-9149-y 18563283
48. L Fontana JC Eagon ME Trujillo PE Scherer S Klein 2007 Visceral fat adipokine secretion is associated with systemic inflammation in obese humans Diabetes 56 1010 1013 10.2337/db06-1656 17287468
49. K Fuller C Murphy B Kirstein SW Fox TJ Chambers 2002 TNFα potently activates osteoclasts, through a direct action independent of and strongly synergistic with RANKL Endocrinology 143 1108 1118 10.1210/en.143.3.1108 11861538
50. MF White 2003 Insulin signaling in health and disease Science 302 1710 1711 10.1126/science.1092952 14657487
51. AR Nawrocki PE Scherer 2004 The delicate balance between fat and muscle: adipokines in metabolic disease and musculoskeletal inflammation Curr Opin Pharmacol 4 281 289 10.1016/j.coph.2004.03.003 15140421
52. CM Steppan J Wang EL Whiteman MJ Birnbaum MA Lazar 2005 Activation of SOCS-3 by resistin Mol Cell Biol 25 1569 1575 10.1128/MCB.25.4.1569-1575.2005 15684405
53. KM Thrailkill CK Lumpkin Jr RC Bunn SF Kemp JL Fowlkes 2005 Is insulin an anabolic agent in bone? Dissecting the diabetic bone for clues Am J Physiol Endocrinol Metab 289 E735 E745 10.1152/ajpendo.00159.2005 16215165
54. N Kawamura F Kugimiya Y Oshima S Ohba T Ikeda T Saito Y Shinoda Y Kawasaki N Ogata K Hoshi T Akiyama WS Chen N Hay K Tobe T Kadowaki Y Azuma S Tanaka K Nakamura UI Chung H Kawaguchi 2007 Akt1 in osteoblasts and osteoclasts controls bone remodeling PLoS ONE 2 e1058 10.1371/journal.pone.0001058 17957242