Relaxed tRNA specificity of the Staphylococcus aureus aspartyl-tRNA synthetase enables RNA-dependent asparagine biosynthesis

FEBS Letters

Volumn 588, Issue 9, 2014, Pages 1808-1812

  Mladenova, Stefani R ^a   Stein, Kathryn R ^a   Bartlett, Lianne ^a   Sheppard, Kelly ^a  

^a SKIDMORE COLLEGE   (United States)

Author keywords

Asparagine biosynthesis; Aspartyl tRNA synthetase; RNA dependent; Staphylococcus aureus; tRNA

Indexed keywords

ASPARAGINE; ASPARTATE TRANSFER RNA LIGASE; GATCAB PROTEIN; TRANSFER RNA; TRANSFERASE; UNCLASSIFIED DRUG;

AMINO ACID SYNTHESIS; AMINOACYLATION; ARTICLE; AUXOTROPHY; CONTROLLED STUDY; ENZYME ACTIVITY; ESCHERICHIA COLI; IN VITRO STUDY; IN VIVO STUDY; NONHUMAN; PRIORITY JOURNAL; RNA ANALYSIS; SEQUENCE ANALYSIS; STAPHYLOCOCCUS AUREUS;

STAPHYLOCOCCUS AUREUS;

ASPARAGINE BIOSYNTHESIS; ASPARTYL-TRNA SYNTHETASE; RNA-DEPENDENT; STAPHYLOCOCCUS AUREUS; TRNA;

AMINO ACID SEQUENCE; AMINOACYLATION; ASPARAGINE; ASPARTATE-TRNA LIGASE; ESCHERICHIA COLI; KINETICS; MOLECULAR SEQUENCE DATA; RNA, BACTERIAL; RNA, TRANSFER, ASN; RNA, TRANSFER, ASP; STAPHYLOCOCCUS AUREUS; SUBSTRATE SPECIFICITY;

EID: 84899651208     PISSN: 00145793     EISSN: 18733468     Source Type: Journal    
DOI: 10.1016/j.febslet.2014.03.042     Document Type: Article

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