Gain-of-function KCNH2 mutations in patients with Brugada syndrome

Journal of Cardiovascular Electrophysiology

Volumn 25, Issue 5, 2014, Pages 522-530

  Wang, Qi ^a   Ohno, Seiko ^a   Ding, Wei Guang ^a   Fukuyama, Megumi ^a   Miyamoto, Akashi ^a   Itoh, Hideki ^a   Makiyama, Takeru ^b   Wu, Jie ^a   Bai, Jiayu ^a   Hasegawa, Kanae ^a   Shinohara, Tetsuji ^c   Takahashi, Naohiko ^c   Shimizu, Akihiko ^d   Matsuura, Hiroshi ^a   Horie, Minoru ^a  

^a SHIGA UNIVERSITY OF MEDICAL SCIENCE   (Japan)

^b KYOTO UNIVERSITY   (Japan)

^c OITA UNIVERSITY   (Japan)

^d YAMAGUCHI UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

Brugada syndrome; KCNH2; mutation; patch clamp; ventricular tachycardia

Indexed keywords

POTASSIUM CHANNEL; POTASSIUM CHANNEL KCNH2; SODIUM CHANNEL NAV1.5; UNCLASSIFIED DRUG; CACNA1C PROTEIN, HUMAN; CALCIUM CHANNEL L TYPE; ERG1 POTASSIUM CHANNEL; POTASSIUM CHANNEL HERG; SCN5A PROTEIN, HUMAN;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BRUGADA SYNDROME; CASE REPORT; CHO CELL LINE; CONTROLLED STUDY; ELECTROCARDIOGRAM; ENZYME INACTIVATION; FEMALE; GAIN OF FUNCTION MUTATION; GENE; HEART VENTRICLE FIBRILLATION; HEART VENTRICLE TACHYCARDIA; HETEROZYGOTE; HUMAN; KCNH2 GENE; MALE; MIDDLE AGED; NONHUMAN; PATCH CLAMP TECHNIQUE; PHENOTYPE; PRIORITY JOURNAL; QRS COMPLEX; QT INTERVAL; ST SEGMENT ELEVATION; SUDDEN CARDIAC DEATH; ACTION POTENTIAL; ANIMAL; COMPARATIVE STUDY; CRICETULUS; ELECTROCARDIOGRAPHY; GENETIC PREDISPOSITION; GENETIC SCREENING; GENETIC TRANSFECTION; GENETICS; KINETICS; METABOLISM; MUTATION; NUCLEOTIDE SEQUENCE; PATHOPHYSIOLOGY; PROCEDURES; PROGNOSIS;

ACTION POTENTIALS; ADULT; ANIMALS; BRUGADA SYNDROME; CALCIUM CHANNELS, L-TYPE; CHO CELLS; CRICETULUS; DNA MUTATIONAL ANALYSIS; ELECTROCARDIOGRAPHY; ETHER-A-GO-GO POTASSIUM CHANNELS; GENETIC PREDISPOSITION TO DISEASE; GENETIC TESTING; HUMANS; KINETICS; MALE; MIDDLE AGED; MUTATION; NAV1.5 VOLTAGE-GATED SODIUM CHANNEL; PATCH-CLAMP TECHNIQUES; PHENOTYPE; PROGNOSIS; TRANSFECTION;

EID: 84899644025     PISSN: 10453873     EISSN: 15408167     Source Type: Journal    
DOI: 10.1111/jce.12361     Document Type: Article

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