Matrix rigidity-modulated cardiovascular organoid formation from embryoid bodies

PLoS ONE

Volumn 9, Issue 4, 2014, Pages

  Shkumatov, Artem ^a   Baek, Kwanghyun ^b   Kong, Hyunjoon ^a  

^a UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

^b University of Illinois at Urbana Champaign   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CARDIOVASCULAR SYSTEM; CELL ADHESION; CELL DIFFERENTIATION; CELL LINEAGE; CELL PROLIFERATION; CELL VIABILITY; CONTROLLED STUDY; CYTOPLASM; ECTODERM; EMBRYO; EMBRYOID BODY; EMBRYONIC STEM CELL; FLOW CYTOMETRY; HEART MUSCLE; HYDROGEL; MESODERM; MORPHOMETRICS; MOUSE; NONHUMAN; POLYMERIZATION; PROTEIN CROSS LINKING; RNA PURIFICATION; TISSUE REGENERATION; VISCOELASTICITY; YOUNG MODULUS; ANIMAL; BRAIN; CELL LINE; CHEMISTRY; COMPUTER PROGRAM; CULTURE TECHNIQUE; CYTOLOGY; IMMUNOHISTOCHEMISTRY; METABOLISM; PHYSIOLOGY; REGENERATION; SCANNING ELECTRON MICROSCOPY; STEM CELL;

ACRYLIC ACID RESIN; COLLAGEN; HYDROGEL; POLYACRYLAMIDE;

ACRYLIC RESINS; ANIMALS; BRAIN; CARDIOVASCULAR SYSTEM; CELL LINE; CELL PROLIFERATION; COLLAGEN; CULTURE TECHNIQUES; EMBRYOID BODIES; HYDROGELS; IMMUNOHISTOCHEMISTRY; MICE; MICROSCOPY, ELECTRON, SCANNING; MYOCARDIUM; ORGANOIDS; REGENERATION; SOFTWARE; STEM CELLS;

EID: 84899638519     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0094764     Document Type: Article

References (25)

1. Carpenedo RL, Sargent CY, McDevitt TC (2007) Rotary suspension culture enhances the efficiency, yield, and homogeneity of embryoid body differentiation. Stem Cells 25: 2224-2234. (Pubitemid 47480481)
2. Liang Y, Jeong J, DeVolder RJ, Cha C, Wang F, et al. (2011) A cell-instructive hydrogel to regulate malignancy of 3D tumor spheroids with matrix rigidity. Biomaterials 32: 9308-9315.
3. Wobus AM, Kaomei G, Shan J, Wellner MC, Rohwedel J, et al. (1997) Retinoic acid accelerates embryonic stem cell-derived cardiac differentiation and enhances development of ventricular cardiomyocytes. J Mol Cell Cardiol 29: 1525-1539. (Pubitemid 27270224)
4. McBurney MW, Jones-Villeneuve EM, Edwards MK, Anderson PJ (1982) Control of muscle and neuronal differentiation in a cultured embryonal carcinoma cell line. Nature 299: 165-167. (Pubitemid 12056794)
5. Yamashita J, Itoh H, Hirashima M, Ogawa M, Nishikawa S, et al. (2000) Flk1-positive cells derived from embryonic stem cells serve as vascular progenitors. Nature 408: 92-96.
6. Kong HJ, Boontheekul T, Mooney DJ (2006) Quantifying the relation between adhesion ligand-receptor bond formation and cell phenotype. Proc Natl Acad Sci U S A 103: 18534-18539. (Pubitemid 44913445)
7. Discher DE, Mooney DJ, Zandstra PW (2009) Growth factors, matrices, and forces combine and control stem cells. Science 324: 1673-1677.
8. Engler AJ, Carag-Krieger C, Johnson CP, Raab M, Tang HY, et al. (2008) Embryonic cardiomyocytes beat best on a matrix with heart-like elasticity: scarlike rigidity inhibits beating. J Cell Sci 121: 3794-3802.
9. ten Berge D, Koole W, Fuerer C, Fish M, Eroglu E, et al. (2008) Wnt signaling mediates self-organization and axis formation in embryoid bodies. Cell Stem Cell 3: 508-518.
10. Rust WL, Sadasivam A, Dunn NR (2006) Three-dimensional extracellular matrix stimulates gastrulation-like events in human embryoid bodies. Stem Cells Dev 15: 889-904. (Pubitemid 46147860)
11. Hsu YC (1972) Differentiation in vitro of mouse embryos beyond the implantation stage. Nature 239: 200-202.
12. Fuchs C, Scheinast M, Pasteiner W, Lagger S, Hofner M, et al. (2012) Selforganization phenomena in embryonic stem cell-derived embryoid bodies: axis formation and breaking of symmetry during cardiomyogenesis. Cells Tissues Organs 195: 377-391.
13. Kong HJ, Smith MK, Mooney DJ (2003) Designing alginate hydrogels to maintain viability of immobilized cells. Biomaterials 24: 4023-4029. (Pubitemid 36798121)
14. Nieto A, Cabrera CM, Catalina P, Cobo F, Barnie A, et al. (2007) Effect of mitomycin-C on human foreskin fibroblasts used as feeders in human embryonic stem cells: immunocytochemistry MIB1 score and DNA ploidy and apoptosis evaluated by flow cytometry. Cell Biol Int 31: 269-278.
15. Mummery C, Ward-van Oostwaard D, Doevendans P, Spijker R, van den Brink S, et al. (2003) Differentiation of human embryonic stem cells to cardiomyocytes: role of coculture with visceral endoderm-like cells. Circulation 107: 2733-2740. (Pubitemid 36667249)
16. Darabi R, Gehlbach K, Bachoo RM, Kamath S, Osawa M, et al. (2008) Functional skeletal muscle regeneration from differentiating embryonic stem cells. Nat Med 14: 134-143. (Pubitemid 351214552)
17. Galvez BG, Sampaolesi M, Barbuti A, Crespi A, Covarello D, et al. (2008) Cardiac mesoangioblasts are committed, self-renewable progenitors, associated with small vessels of juvenile mouse ventricle. Cell Death Differ 15: 1417-1428.
18. Condorelli G, Borello U, De Angelis L, Latronico M, Sirabella D, et al. (2001) Cardiomyocytes induce endothelial cells to trans-differentiate into cardiac muscle: implications for myocardium regeneration. Proc Natl Acad Sci U S A 98: 10733-10738. (Pubitemid 32878690)
19. Tuckwell DS, Humphries MJ (1993) Molecular and cellular biology of integrins. Crit Rev Oncol Hematol 15: 149-171. (Pubitemid 24013567)
20. Discher DE, Janmey P, Wang YL (2005) Tissue cells feel and respond to the stiffness of their substrate. Science 310: 1139-1143. (Pubitemid 41681732)
21. Jacot JG, Martin JC, Hunt DL (2010) Mechanobiology of cardiomyocyte development. J Biomech 43: 93-98.
22. Walsh S, Ponten A, Fleischmann BK, Jovinge S (2010) Cardiomyocyte cell cycle control and growth estimation in vivo-an analysis based on cardiomyocyte nuclei. Cardiovasc Res 86: 365-373.
23. Dang SM, Kyba M, Perlingeiro R, Daley GQ, Zandstra PW (2002) Efficiency of embryoid body formation and hematopoietic development from embryonic stem cells in different culture systems. Biotechnol Bioeng 78: 442-453. (Pubitemid 34712364)
24. Murphy CL, Polak JM (2002) Differentiating embryonic stem cells: GAPDH, but neither HPRT nor beta-tubulin is suitable as an internal standard for measuring RNA levels. Tissue Eng 8: 551-559. (Pubitemid 34857792)
25. Wobus AM, Rohwedel J, Maltsev V, Hescheler J (1995) In vitro cellular models for cardiac development and pharmacotoxicology. Toxicol In Vitro 9: 477-488.